Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Methyl-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
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 PubChem ID
CID: 443391
SID: 14929825
Canonical SMILES
Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1C(F)(F)F
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Compound Formula C22H19F3N4O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.7 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1 nM