Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
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 PubChem ID
CID: 25070582
SID: 56408830
Canonical SMILES
C(c1ccccc1)c1ncc2CCNCCc2n1
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Compound Formula C15H17N3
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 4.5 nM
   TI
   LI
   LO
   TS
2
EC50 = 190 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  4
1
EC50 = 4.5 nM
   TI
   LI
   LO
   TS
2
EC50 = 190 nM
   TI
   LI
   LO
   TS
3
Ki = 160 nM
   TI
   LI
   LO
   TS
4
Ki = 180 nM
   TI
   LI
   LO
   TS