Brief Information of the Compound and Protein
Compound Name
1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-yloxy)-pyridin-3-yl]-amide
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PubChem ID
CID: 24894071
SID: 53776682
Canonical SMILES
Clc1ncccc1Oc1ccc(NC(=O)c2c[nH]c3ccccc23)cn1
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Compound Formula C19H13ClN4O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS