| Compound ID |
Compound Name |
Compound Formula |
|
CP0414431
|
1-cyano-2-[4-(1H-imidazol-5-yl)butyl]-3-(2-phenylsulfanylethyl)guanidine
Show/Hide
|
C17H22N6S
|
5
|
| 1 |
Activity >= 10 nM
|
|
|
| 2 |
EC50 = 33.88 nM
|
|
|
| 3 |
EC50 = 37 nM
|
|
|
| 4 |
EC50 = 37.15 nM
|
|
|
| 5 |
Ki = 57.54 nM
|
|
|
|
CP0383241
|
4-N-[(2,6-dichlorophenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C16H20Cl2N6
|
2
|
| 1 |
EC50 = 1.122 nM
|
|
|
| 2 |
EC50 = 1.413 nM
|
|
|
|
CP0399684
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]butanamide
Show/Hide
|
C11H19N5O
|
1
|
| 1 |
EC50 = 2.57 nM
|
|
|
|
CP0386444
|
(3S)-N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]-3-phenylbutanamide
Show/Hide
|
C17H23N5O
|
1
|
| 1 |
EC50 = 2.63 nM
|
|
|
|
CP0137852
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]propanamide
Show/Hide
|
C10H17N5O
|
1
|
| 1 |
EC50 = 3.02 nM
|
|
|
|
CP0399688
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]-2-methylpropanamide
Show/Hide
|
C11H19N5O
|
1
|
| 1 |
EC50 = 3.715 nM
|
|
|
|
CP0429985
|
(3S)-3-cyclohexyl-N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]butanamide
Show/Hide
|
C17H29N5O
|
1
|
| 1 |
EC50 = 4.571 nM
|
|
|
|
CP0384449
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]acetamide
Show/Hide
|
C9H15N5O
|
1
|
| 1 |
EC50 = 4.898 nM
|
|
|
|
CP0471747
|
4-N-[(2-chlorophenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C16H21ClN6
|
2
|
| 1 |
EC50 = 6.026 nM
|
|
|
| 2 |
EC50 = 19.5 nM
|
|
|
|
CP0374090
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]-3-thiophen-2-ylbutanamide
Show/Hide
|
C15H21N5OS
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
|
CP0387498
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]-3-(1H-indol-3-yl)propanamide
Show/Hide
|
C18H22N6O
|
1
|
| 1 |
EC50 = 7.079 nM
|
|
|
|
CP0377761
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]-3,3-diphenylpropanamide
Show/Hide
|
C22H25N5O
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
EC50 = 8.6 nM
|
|
|
|
CP0036920
|
2-(1H-imidazol-4-yl)ethan-1-amine
Show/Hide
|
C5H9N3
|
10
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
EC50 = 9.12 nM
|
|
|
| 3 |
EC50 = 11 nM
|
|
|
| 4 |
EC50 = 11.6 nM
|
|
|
| 5 |
EC50 = 11.75 nM
|
|
|
| 6 |
EC50 = 12.02 nM
|
|
|
| 7 |
EC50 = 12.59 nM
|
|
|
| 8 |
EC50 = 13.8 nM
|
|
|
| 9 |
EC50 = 20.42 nM
|
|
|
| 10 |
Ki = 7.943 nM
|
|
|
|
CP0424970
|
2-[3-(1H-imidazol-5-yl)propyl]guanidine
Show/Hide
|
C7H13N5
|
1
|
| 1 |
EC50 = 8.128 nM
|
|
|
|
CP0386442
|
(3R)-3-cyclohexyl-N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]butanamide
Show/Hide
|
C17H29N5O
|
1
|
| 1 |
EC50 = 8.318 nM
|
|
|
|
CP0430901
|
4-N-[(2-methylphenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C17H24N6
|
2
|
| 1 |
EC50 = 8.511 nM
|
|
|
| 2 |
EC50 = 11.75 nM
|
|
|
|
CP0179287
|
N,N'-bis[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]decanediamide
Show/Hide
|
C24H40N10O2
|
1
|
| 1 |
EC50 = 8.511 nM
|
|
|
|
CP0413923
|
N'-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]decanediamide
Show/Hide
|
C25H42N10O2S
|
1
|
| 1 |
EC50 = 8.511 nM
|
|
|
|
CP0382883
|
1-cyano-3-[[(1S,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-2-(2-methylpropyl)guanidine
Show/Hide
|
C15H24N6
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0059545
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]-3-phenylbutanamide
Show/Hide
|
C17H23N5O
|
3
|
| 1 |
EC50 = 15.14 nM
|
|
|
| 2 |
EC50 = 15.3 nM
|
|
|
| 3 |
EC50 = 15.85 nM
|
|
|
|
CP0041262
|
5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-indole
Show/Hide
|
C14H16ClN3O
|
5
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
| 3 |
Ki = 18.62 nM
|
|
|
| 4 |
Ki = 63.1 nM
|
|
|
| 5 |
Ki = 69 nM
|
|
|
|
CP0382681
|
UR-AK51
Show/Hide
|
C16H21N5O
|
1
|
| 1 |
EC50 = 15.85 nM
|
|
|
|
CP0377446
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]-2-(1H-indol-3-yl)acetamide
Show/Hide
|
C17H20N6O
|
1
|
| 1 |
EC50 = 19.05 nM
|
|
|
|
CP0383664
|
4-N-[(4-fluorophenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C16H21FN6
|
2
|
| 1 |
EC50 = 20.89 nM
|
|
|
| 2 |
EC50 = 91.2 nM
|
|
|
|
CP0171842
|
4-N-benzyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C16H22N6
|
2
|
| 1 |
EC50 = 21.38 nM
|
|
|
| 2 |
Ki = 98 nM
|
|
|
|
CP0383470
|
(3R)-N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]-3-phenylbutanamide
Show/Hide
|
C17H23N5O
|
1
|
| 1 |
EC50 = 22.91 nM
|
|
|
|
CP0444677
|
N-[2-[[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]amino]-2-oxoethyl]-1H-indole-2-carboxamide
Show/Hide
|
C18H21N7O2
|
1
|
| 1 |
EC50 = 28.18 nM
|
|
|
|
CP0469551
|
4-N-[(4-chlorophenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C16H21ClN6
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
Ki = 71 nM
|
|
|
|
CP0398855
|
2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine
Show/Hide
|
C6H11N3
|
3
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
EC50 = 70.79 nM
|
|
|
| 3 |
Ki = 50.12 nM
|
|
|
|
CP0424971
|
N-[3-[[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]amino]-3-oxopropyl]-1H-indole-2-carboxamide
Show/Hide
|
C19H23N7O2
|
1
|
| 1 |
EC50 = 33.11 nM
|
|
|
|
CP0470095
|
4-(isoindolin-2-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C17H22N6
|
2
|
| 1 |
EC50 = 37.15 nM
|
|
|
| 2 |
Ki = 248 nM
|
|
|
|
CP0408788
|
N,N'-bis[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]octanediamide
Show/Hide
|
C22H36N10O2
|
1
|
| 1 |
EC50 = 41.69 nM
|
|
|
|
CP0469549
|
4-(3,4-Dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C18H24N6
|
2
|
| 1 |
EC50 = 43.65 nM
|
|
|
| 2 |
Ki = 146 nM
|
|
|
|
CP0509134
|
2-(diaminomethylideneamino)ethyl ethanimidothioate
Show/Hide
|
C5H12N4S
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0469550
|
4-N-[(3,4-dichlorophenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C16H20Cl2N6
|
2
|
| 1 |
EC50 = 56.23 nM
|
|
|
| 2 |
Ki = 150 nM
|
|
|
|
CP0434681
|
N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]-3-phenyl-3-(1,3-thiazol-2-yl)propanamide
Show/Hide
|
C19H22N6OS
|
1
|
| 1 |
EC50 = 66.3 nM
|
|
|
|
CP0044460
|
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
Show/Hide
|
C15H24N4S
|
8
|
| 1 |
EC50 = 70.79 nM
|
|
|
| 2 |
EC50 = 89.13 nM
|
|
|
| 3 |
EC50 = 109.65 nM
|
|
|
| 4 |
EC50 = 416.87 nM
|
|
|
| 5 |
Ki = 63.1 nM
|
|
|
| 6 |
Ki = 178 nM
|
|
|
| 7 |
Ki = 426.58 nM
|
|
|
| 8 |
Ki = 501.19 nM
|
|
|
|
CP0413890
|
N,N'-bis[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]hexanediamide
Show/Hide
|
C20H32N10O2
|
1
|
| 1 |
EC50 = 79.43 nM
|
|
|
|
CP0485831
|
4-((2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-ylamino)methyl)phenol
Show/Hide
|
C16H22N6O
|
2
|
| 1 |
EC50 = 102.33 nM
|
|
|
| 2 |
Ki = 237 nM
|
|
|
|
CP0471748
|
4-N-[(4-methylphenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C17H24N6
|
2
|
| 1 |
EC50 = 104.71 nM
|
|
|
| 2 |
Ki = 205 nM
|
|
|
|
CP0434661
|
1-cyano-3-[4-(1H-imidazol-5-yl)cyclohexyl]-2-(2-phenylsulfanylethyl)guanidine
Show/Hide
|
C19H24N6S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0421641
|
1-cyano-3-[4-(1H-imidazol-5-yl)butyl]-2-(2-methylpropyl)guanidine
Show/Hide
|
C13H22N6
|
1
|
| 1 |
EC50 = 120.23 nM
|
|
|
|
CP0377314
|
1-cyano-2-[[(1S,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-3-(3-phenylpropyl)guanidine
Show/Hide
|
C20H26N6
|
1
|
| 1 |
EC50 = 125 nM
|
|
|
|
CP0428893
|
1-cyano-2-[4-(1H-imidazol-5-yl)butyl]-3-(3-phenylbutyl)guanidine
Show/Hide
|
C19H26N6
|
1
|
| 1 |
EC50 = 141.25 nM
|
|
|
|
CP0424645
|
[(1R,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methanamine
Show/Hide
|
C9H15N3
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0384447
|
N-[3-[[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]amino]-3-oxopropyl]-N-methyl-1H-indole-2-carboxamide
Show/Hide
|
C20H25N7O2
|
1
|
| 1 |
EC50 = 151.36 nM
|
|
|
|
CP0430371
|
1-cyano-3-[4-(1H-imidazol-5-yl)butyl]-2-(3-phenylpropyl)guanidine
Show/Hide
|
C18H24N6
|
1
|
| 1 |
EC50 = 151.36 nM
|
|
|
|
CP0430370
|
1-cyano-2-[4-(1H-imidazol-5-yl)butyl]guanidine
Show/Hide
|
C9H14N6
|
1
|
| 1 |
EC50 = 169.82 nM
|
|
|
|
CP0504420
|
4-N-[(3-chlorophenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C16H21ClN6
|
2
|
| 1 |
EC50 = 199.53 nM
|
|
|
| 2 |
Ki = 290 nM
|
|
|
|
CP0382910
|
1-cyano-3-[[(1R,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-2-(2-methylpropyl)guanidine
Show/Hide
|
C15H24N6
|
1
|
| 1 |
EC50 = 202 nM
|
|
|
|
CP0398553
|
1-cyano-3-cyclopropyl-2-[[(1S,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]guanidine
Show/Hide
|
C14H20N6
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
|
CP0382882
|
1-cyano-3-cyclopropyl-2-[[(1R,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]guanidine
Show/Hide
|
C14H20N6
|
1
|
| 1 |
EC50 = 245 nM
|
|
|
|
CP0849403
|
2-Cyano-1-[4-(5-methyl-1H-imidazol-4-yl)butyl]-3-[2-(phenylthio)ethyl]guanidine
Show/Hide
|
C18H24N6S
|
1
|
| 1 |
EC50 = 245.47 nM
|
|
|
|
CP0439106
|
4-N-[(3-methylphenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C17H24N6
|
2
|
| 1 |
EC50 = 269.15 nM
|
|
|
| 2 |
Ki = 282 nM
|
|
|
|
CP0247209
|
2,4-diamino-5,6-disubstituted pyrimidine, 6
Show/Hide
|
C17H21N5
|
2
|
| 1 |
EC50 = 295.12 nM
|
|
|
| 2 |
Ki = 186.21 nM
|
|
|
|
CP0439078
|
1-cyano-2-[4-(1H-imidazol-5-yl)butyl]-3-propan-2-ylguanidine
Show/Hide
|
C12H20N6
|
1
|
| 1 |
EC50 = 331.13 nM
|
|
|
|
CP0396478
|
N,N'-bis[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]hexadecanediamide
Show/Hide
|
C30H52N10O2
|
1
|
| 1 |
EC50 = 338.84 nM
|
|
|
|
CP0382912
|
1-cyano-2-[[(1R,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-3-(3-phenylpropyl)guanidine
Show/Hide
|
C20H26N6
|
1
|
| 1 |
EC50 = 372 nM
|
|
|
|
CP0866598
|
2-Cyano-1-[3-(2-methyl-1H-imidazol-4-yl)propyl]-3-[2-(phenylthio)ethyl]guanidine
Show/Hide
|
C17H22N6S
|
1
|
| 1 |
EC50 = 467.74 nM
|
|
|
|
CP0480094
|
6-(4-Methylpiperazin-1-yl)-N4-(3-nitrobenzyl)pyrimidine-2,4-diamine
Show/Hide
|
C16H21N7O2
|
2
|
| 1 |
EC50 = 478.63 nM
|
|
|
| 2 |
Ki = 538 nM
|
|
|
|
CP0377310
|
1-cyano-2-[[(1S,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-3-(2-phenoxyethyl)guanidine
Show/Hide
|
C19H24N6O
|
1
|
| 1 |
EC50 = 524 nM
|
|
|
|
CP0382901
|
1-cyano-2-[[(1S,3R)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-3-(2-phenylsulfanylethyl)guanidine
Show/Hide
|
C19H24N6S
|
2
|
| 1 |
EC50 = 549 nM
|
|
|
| 2 |
Ki = 290 nM
|
|
|
|
CP0877422
|
2-Cyano-1-methyl-3-[3-(2-methyl-1H-imidazol-4-yl)propyl]guanidine
Show/Hide
|
C10H16N6
|
1
|
| 1 |
EC50 = 549.54 nM
|
|
|
|
CP0439077
|
1-cyano-3-[4-(1H-imidazol-5-yl)butyl]-2-(3-pyridin-2-ylpropyl)guanidine
Show/Hide
|
C17H23N7
|
1
|
| 1 |
EC50 = 575.44 nM
|
|
|
|
CP0439104
|
4-((2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-ylamino)methyl)benzonitrile
Show/Hide
|
C17H21N7
|
2
|
| 1 |
EC50 = 602.56 nM
|
|
|
| 2 |
Ki = 341 nM
|
|
|
|
CP0421640
|
1-cyano-3-ethyl-2-[4-(1H-imidazol-5-yl)butyl]guanidine
Show/Hide
|
C11H18N6
|
1
|
| 1 |
EC50 = 707.95 nM
|
|
|
|
CP0421638
|
1-cyano-3-[3-(1H-imidazol-5-yl)propyl]-2-(3-phenylpropyl)guanidine
Show/Hide
|
C17H22N6
|
1
|
| 1 |
EC50 = 758.58 nM
|
|
|
|
CP0866592
|
N1-[3-(1H-Imidazol-2-yl)propyl]-N2-[3-(thiophen-2-yl)butanoyl]guanidine
Show/Hide
|
C15H21N5OS
|
1
|
| 1 |
EC50 = 776.25 nM
|
|
|
|
CP0468341
|
N-benzyl-4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
Show/Hide
|
C22H25N5
|
2
|
| 1 |
EC50 = 912.01 nM
|
|
|
| 2 |
Ki = 954.99 nM
|
|
|
|
CP0401126
|
N-benzyl-4-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[h]quinazolin-2-amine
Show/Hide
|
C24H27N5
|
2
|
| 1 |
EC50 = 933.25 nM
|
|
|
| 2 |
Ki = 1584.89 nM
|
|
|
|
CP0223330
|
1-cyano-3-[4-(1H-imidazol-5-yl)butyl]-2-methylguanidine
Show/Hide
|
C10H16N6
|
1
|
| 1 |
EC50 = 954.99 nM
|
|
|
|
CP0677611
|
N1-[3-(1H-Imidazol-1-yl)propyl]-N2-(3-phenylbutanoyl)guanidine
Show/Hide
|
C17H23N5O
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0428890
|
1-cyano-2-[4-(1H-imidazol-5-yl)butyl]-3-(2-phenylethyl)guanidine
Show/Hide
|
C17H22N6
|
1
|
| 1 |
EC50 = 1096.48 nM
|
|
|
|
CP0382908
|
1-cyano-3-[[(1R,3R)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-2-methylguanidine
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C12H18N6
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2
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| 1 |
EC50 = 1100 nM
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| 2 |
Ki = 870 nM
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CP0439080
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1-cyano-3-[4-(1H-imidazol-5-yl)butyl]-2-(3-pyridin-3-ylpropyl)guanidine
Show/Hide
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C17H23N7
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1
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| 1 |
EC50 = 1202.26 nM
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CP0428889
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1-cyano-2-[3-(1H-imidazol-5-yl)propyl]-3-(2-phenylsulfanylethyl)guanidine
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C16H20N6S
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1
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| 1 |
EC50 = 1288.25 nM
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CP0429981
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(3S)-N-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-cyclohexylbutanamide
Show/Hide
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C18H31N5OS
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1
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| 1 |
EC50 = 1380.38 nM
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CP0204765
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2-[2-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]ethanamine
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C12H12F3N3
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2
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| 1 |
EC50 = 1584.89 nM
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| 2 |
Ki = 1258.93 nM
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CP0382909
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[(1S,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methanamine
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C9H15N3
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1
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| 1 |
EC50 = 1710 nM
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CP0430369
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1-cyano-3-[4-(1H-imidazol-5-yl)butyl]-2-(3-pyridin-4-ylpropyl)guanidine
Show/Hide
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C17H23N7
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1
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| 1 |
EC50 = 2570.4 nM
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CP0377315
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1-cyano-3-[[(1S,3R)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-2-methylguanidine
Show/Hide
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C12H18N6
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2
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| 1 |
EC50 = 2675 nM
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| 2 |
Ki = 3500 nM
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CP0732535
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N1-[3-(1H-Imidazol-2-yl)propyl]-N2-(3-phenylbutanoyl)guanidine
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C17H23N5O
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1
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| 1 |
EC50 = 2884.03 nM
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CP0768460
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2-Cyano-1-methyl-3-[4-(5-methyl-1H-imidazol-4-yl)butyl]guanidine
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C11H18N6
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1
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| 1 |
EC50 = 3630.78 nM
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CP0376703
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2-(2-methyl-1H-imidazol-4-yl)ethan-1-amine
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C6H11N3
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2
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| 1 |
EC50 = 3981.07 nM
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| 2 |
Ki = 794.33 nM
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CP0851237
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(+/-)-N-(N-(3-(2-amino-4-methylthiazol-5-yl)propyl)carbamimidoyl)-3-cyclohexylbutanamide
Show/Hide
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C18H31N5OS
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1
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| 1 |
EC50 = 6025.6 nM
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CP0421636
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1-cyano-2-(3,3-diphenylpropyl)-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
Show/Hide
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C24H28N6S
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1
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| 1 |
EC50 > 10000 nM
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CP0430374
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1-cyano-3-[2-(1H-imidazol-5-yl)ethyl]-2-(4-phenylbutyl)guanidine
Show/Hide
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C17H22N6
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1
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| 1 |
EC50 > 10000 nM
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CP0377116
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(3R)-N-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-cyclohexylbutanamide
Show/Hide
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C18H31N5OS
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1
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| 1 |
EC50 > 10000 nM
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CP0377120
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(3S)-N-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-phenylbutanamide
Show/Hide
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C18H25N5OS
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1
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| 1 |
EC50 > 10000 nM
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CP0390527
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(3R)-N-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-phenylbutanamide
Show/Hide
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C18H25N5OS
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1
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| 1 |
EC50 > 10000 nM
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CP0840778
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N-(amino(3-(2-amino-4-methylthiazol-5-yl)propylamino)methylene)-3-phenylbutanamide
Show/Hide
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C18H25N5OS
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1
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| 1 |
EC50 > 10000 nM
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CP0376704
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2-(3-Bromophenyl)histamine
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C11H12BrN3
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2
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| 1 |
EC50 = 10000 nM
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| 2 |
Ki = 1584.89 nM
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CP0428793
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1H-indol-2-yl-[4-[2-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl-methylamino]ethyl]piperazin-1-yl]methanone
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C31H38N6O2
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2
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| 1 |
EC50 > 100000 nM
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| 2 |
Ki = 8912.51 nM
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CP0391407
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N,N'-bis[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]docosanediamide
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C36H64N10O2
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1
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| 1 |
EC50 > 1000 nM
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CP0422990
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N-(2,2-dimethylpropyl)-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine;2,2,2-trifluoroacetic acid
Show/Hide
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C18H27F6N5O4
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1
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| 1 |
Ki = 3.802 nM
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CP0487568
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N-(2,2-dimethylpropyl)-4-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)pyrimidin-2-amine
Show/Hide
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C15H22N6
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1
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| 1 |
Ki = 5.012 nM
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CP0422989
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N-(2,2-dimethylpropyl)-4-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)pyrimidin-2-amine;2,2,2-trifluoroacetic acid
Show/Hide
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C19H24F6N6O4
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1
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| 1 |
Ki = 5.129 nM
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CP0098027
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2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide
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C6H10N4S
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1
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| 1 |
Ki = 6.31 nM
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CP0412799
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1-[4-(1H-imidazol-4-yl)butyl]-3-propan-2-ylthiourea
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C11H20N4S
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1
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| 1 |
Ki = 7.943 nM
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CP0437516
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Clobenprobit
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C15H19ClN4S
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1
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| 1 |
Ki = 7.943 nM
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CP0422988
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4-[(3R)-3-aminopyrrolidin-1-yl]-N-(2,2-dimethylpropyl)pyrimidin-2-amine;2,2,2-trifluoroacetic acid
Show/Hide
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C17H25F6N5O4
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1
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| 1 |
Ki = 8.511 nM
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CP0185384
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4-(1H-imidazol-5-yl)butan-1-amine
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C7H13N3
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1
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| 1 |
Ki = 10 nM
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CP0437514
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VUF 8328
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C7H12N4S
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1
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| 1 |
Ki = 10 nM
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CP0437519
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1-[4-(1H-imidazol-4-yl)butyl]-3-propylthiourea
Show/Hide
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C11H20N4S
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1
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| 1 |
Ki = 10 nM
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CP0424193
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4-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-N-(2,2-dimethylpropyl)pyrimidin-2-amine;2,2,2-trifluoroacetic acid
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C19H29F6N5O4
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1
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| 1 |
Ki = 11.75 nM
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CP0214392
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5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole
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C13H15IN2O
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1
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| 1 |
Ki = 12.59 nM
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CP0487580
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4-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-N-(2,2-dimethylpropyl)pyrimidin-2-amine
Show/Hide
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C15H27N5
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1
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| 1 |
Ki = 12.59 nM
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CP0823737
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SID50106398
Show/Hide
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C5H11Cl2N3
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2
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| 1 |
Ki = 12.59 nM
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| 2 |
Ki = 63.1 nM
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CP0867474
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4-(1H-Imidazol-4-yl)butan-1-amine bis(2,2,2-trifluoroacetate)
Show/Hide
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C11H15F6N3O4
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1
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| 1 |
Ki = 12.59 nM
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CP0423018
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4-(1,4-diazepan-1-yl)-N-(2,2-dimethylpropyl)pyrimidin-2-amine;2,2,2-trifluoroacetic acid
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C18H27F6N5O4
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1
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| 1 |
Ki = 13.18 nM
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CP0388279
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4-[(1E,3E)-4-[1-[4-(1H-imidazol-5-yl)butyl]-2,6-dimethylpyridin-1-ium-4-yl]buta-1,3-dienyl]-N,N-dimethylaniline;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
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C30H34F6N4O4
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1
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| 1 |
Ki = 14.13 nM
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CP0110239
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4-(1H-imidazol-4-ylmethyl)piperidine
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C9H15N3
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1
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| 1 |
Ki = 19.95 nM
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CP0186261
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2-[3-(1H-imidazol-5-yl)propyl]-1-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
Show/Hide
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C14H23N7S
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1
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| 1 |
Ki = 25.12 nM
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CP0380243
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3-ethyl-1-[4-(1H-imidazol-4-yl)butyl]thiourea
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C10H18N4S
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1
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| 1 |
Ki = 25.12 nM
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CP0448304
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3-ethyl-1-[5-(1H-imidazol-4-yl)pentyl]thiourea
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C11H20N4S
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1
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| 1 |
Ki = 25.12 nM
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CP0108024
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3-(1H-imidazol-5-yl)propan-1-amine
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C6H11N3
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1
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| 1 |
Ki = 31.62 nM
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CP0202795
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2-(diaminomethylideneamino)ethyl carbamimidothioate
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C4H11N5S
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1
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| 1 |
Ki = 31.62 nM
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CP0867473
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3-(1H-Imidazol-4-yl)propan-1-amine bis(2,2,2-trifluoroacetate)
Show/Hide
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C10H13F6N3O4
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1
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| 1 |
Ki = 31.62 nM
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CP0416437
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4-[(1E,3E)-4-[1-[5-(1H-imidazol-5-yl)pentyl]-2,6-dimethylpyridin-1-ium-4-yl]buta-1,3-dienyl]-N,N-dimethylaniline;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
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C31H36F6N4O4
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1
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| 1 |
Ki = 33.88 nM
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CP0444568
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4-N-(3-aminopropyl)-2-N-(2,2-dimethylpropyl)pyrimidine-2,4-diamine;2,2,2-trifluoroacetic acid
Show/Hide
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C16H25F6N5O4
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1
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| 1 |
Ki = 36.31 nM
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CP0057002
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1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea
Show/Hide
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C9H16N4S
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1
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| 1 |
Ki = 39.81 nM
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CP0270914
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6-chloro-2-(4-methylpiperazin-1-yl)-N-(thiophen-2-ylmethyl)quinazolin-4-amine
Show/Hide
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C18H20ClN5S
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1
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| 1 |
Ki = 42.66 nM
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CP0213459
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3-(1H-imidazol-4-yl)propylphenylmethyl ether
Show/Hide
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C13H16N2O
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1
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| 1 |
Ki = 50.12 nM
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CP0380240
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1-benzyl-3-[4-(1H-imidazol-4-yl)butyl]thiourea
Show/Hide
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C15H20N4S
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1
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| 1 |
Ki = 50.12 nM
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CP0041493
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Clobenpropit
Show/Hide
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C14H17ClN4S
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1
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| 1 |
Ki = 50.12 nM
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CP0437520
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3-[4-(1H-imidazol-4-yl)butyl]-1-(2-phenylethyl)thiourea
Show/Hide
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C16H22N4S
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1
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| 1 |
Ki = 63.1 nM
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CP0424196
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N-(2,2-dimethylpropyl)-4-(4-methyl-1,4-diazepan-1-yl)pyrimidin-2-amine;2,2,2-trifluoroacetic acid
Show/Hide
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C19H29F6N5O4
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1
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| 1 |
Ki = 63.1 nM
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CP0422981
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2-[(3R)-1-[2-(2,2-dimethylpropylamino)pyrimidin-4-yl]pyrrolidin-3-yl]guanidine;2,2,2-trifluoroacetic acid
Show/Hide
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C18H27F6N7O4
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1
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| 1 |
Ki = 69.18 nM
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CP0180153
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7-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
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C18H18ClN3O
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1
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| 1 |
Ki = 102.33 nM
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CP0422983
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N-(2,2-dimethylpropyl)-4-(4-methylpiperazin-1-yl)pyrimidin-2-amine;2,2,2-trifluoroacetic acid
Show/Hide
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C18H27F6N5O4
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1
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| 1 |
Ki = 114.82 nM
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CP0433666
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((S)-2-Methyl-butyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester; compound with (E)-but-2-enedioic acid
Show/Hide
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C12H21N3O2
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1
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| 1 |
Ki = 118 nM
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CP0087269
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(3-Methyl-pentyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester; compound with (E)-but-2-enedioic acid
Show/Hide
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C13H23N3O2
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2
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| 1 |
Ki = 123 nM
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| 2 |
Ki = 1230.27 nM
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CP0100890
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1-cyano-3-[[(2R,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
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C11H16N6O
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1
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| 1 |
Ki = 125.89 nM
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CP0377744
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1-[(4-chlorophenyl)methyl]-3-[5-(1H-imidazol-4-yl)pentyl]thiourea
Show/Hide
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C16H21ClN4S
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1
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| 1 |
Ki = 125.89 nM
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CP0249606
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(1H-Indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
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C14H17N3O
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1
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| 1 |
Ki = 138.04 nM
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CP0895071
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3-(1H-Imidazol-4-yl)propyl2-cyclohexylethylcarbamate hydrogenmaleate
Show/Hide
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C19H29N3O6
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1
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| 1 |
Ki = 154 nM
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CP0847652
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3-(1H-imidazol-4-yl)propyl 2-cyclopropylethylcarbamate maleate
Show/Hide
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C16H23N3O6
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1
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| 1 |
Ki = 155 nM
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CP0390721
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4-(cyclohexylmethyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C15H26N6
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1
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| 1 |
Ki = 160 nM
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CP0430405
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(2-Methyl-pentyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester; compound with (E)-but-2-enedioic acid
Show/Hide
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C13H23N3O2
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1
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| 1 |
Ki = 162 nM
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CP0430105
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4-(4-methylpiperazin-1-yl)-6-propyl-1,3,5-triazin-2-amine
Show/Hide
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C11H20N6
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1
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| 1 |
Ki = 185 nM
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CP0893591
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N-Neopentyl-4-(piperazin-1-yl)pyrimidin-2-amine Bis(2,2,2-trifluoroacetate)
Show/Hide
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C17H25F6N5O4
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1
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| 1 |
Ki = 186.21 nM
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CP0279022
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1-cyano-3-[[(2S,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
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C11H16N6O
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1
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| 1 |
Ki = 199.53 nM
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CP0209146
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4-(4-chlorophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C14H17ClN6
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1
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| 1 |
Ki = 203 nM
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CP0422980
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4-N-(2-aminoethyl)-2-N-(2,2-dimethylpropyl)pyrimidine-2,4-diamine;2,2,2-trifluoroacetic acid
Show/Hide
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C15H23F6N5O4
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1
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| 1 |
Ki = 204.17 nM
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CP0534529
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2-N-(2,2-dimethylpropyl)-4-N-[2-(1H-imidazol-5-yl)ethyl]pyrimidine-2,4-diamine;2,2,2-trifluoroacetic acid
Show/Hide
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C18H24F6N6O4
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1
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| 1 |
Ki = 204.17 nM
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CP0430107
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4-(2,2-dimethylpropyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C13H24N6
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1
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| 1 |
Ki = 247 nM
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CP0047136
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(2R)-1-(1H-imidazol-5-yl)propan-2-amine
Show/Hide
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C6H11N3
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1
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| 1 |
Ki = 251.19 nM
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CP0208579
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4( 5)-( 5-aminopenty1)-lH-imidazole
Show/Hide
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C8H15N3
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1
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| 1 |
Ki = 251.19 nM
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CP0376332
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4-(1H-imidazol-5-ylmethyl)pyridine
Show/Hide
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C9H9N3
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1
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| 1 |
Ki = 251.19 nM
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CP0224333
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4-[(E)-2-(3-chlorophenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H19ClN6
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1
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| 1 |
Ki = 253 nM
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CP0473652
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4-(4-methylpiperazin-1-yl)-6-propan-2-yl-1,3,5-triazin-2-amine
Show/Hide
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C11H20N6
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1
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| 1 |
Ki = 277 nM
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CP0459484
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(1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C13H16N4O
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1
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| 1 |
Ki = 288.4 nM
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CP0387512
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6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
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C9H16N6
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2
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| 1 |
Ki = 290 nM
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| 2 |
Ki = 530 nM
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CP0428877
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((R)-sec-Butyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester; compound with (E)-but-2-enedioic acid
Show/Hide
|
C11H19N3O2
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1
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| 1 |
Ki = 290 nM
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CP0437820
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4-[(1E,3E)-4-[2,6-dimethyl-1-[3-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)propyl]pyridin-1-ium-4-yl]buta-1,3-dienyl]-N,N-dimethylaniline;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
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C34H38F9N5O6
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1
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| 1 |
Ki = 295.12 nM
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CP0422987
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2-N-(2,2-dimethylpropyl)-4-N-pyrrolidin-3-ylpyrimidine-2,4-diamine;2,2,2-trifluoroacetic acid
Show/Hide
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C17H25F6N5O4
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1
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| 1 |
Ki = 309.03 nM
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CP0061272
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N(alpha)-Methylhistamine
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C6H11N3
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1
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| 1 |
Ki = 316.23 nM
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CP0250505
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3-(dimethylamino)propyl carbamimidothioate
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C6H15N3S
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1
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| 1 |
Ki = 316.23 nM
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CP0847653
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3-(1H-Imidazol-4-yl)propylbut-3-enylcarbamate hydrogenmaleate
Show/Hide
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C15H21N3O6
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1
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| 1 |
Ki = 378 nM
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CP0483634
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4-(4-fluorophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C14H17FN6
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1
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| 1 |
Ki = 378 nM
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CP0482188
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6-(4-fluorophenyl)-4-piperazin-1-yl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C16H17FN6
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1
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| 1 |
Ki = 390 nM
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CP0172969
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5-[(2R,5S)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
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C15H18N2O2
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1
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| 1 |
Ki = 398.11 nM
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CP0440801
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4-(3-chlorophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C14H17ClN6
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1
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| 1 |
Ki = 408 nM
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CP0508788
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N-benzyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-amine
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C16H21N5
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1
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| 1 |
Ki = 417 nM
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CP0931008
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3-(1H-imidazol-4-yl)propyl pent-4-enylcarbamate hydrogenmalate
Show/Hide
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C16H23N3O6
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1
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| 1 |
Ki = 421 nM
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CP0470022
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((R)-1-Methyl-pentyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester; compound with (E)-but-2-enedioic acid
Show/Hide
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C13H23N3O2
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1
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| 1 |
Ki = 426 nM
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CP0541967
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4-(4-methylphenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
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C15H20N6
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1
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| 1 |
Ki = 431 nM
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CP0534528
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2-N-(2,2-dimethylpropyl)-4-N-[3-(1H-imidazol-5-yl)propyl]pyrimidine-2,4-diamine;2,2,2-trifluoroacetic acid
Show/Hide
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C19H26F6N6O4
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1
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| 1 |
Ki = 446.68 nM
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CP0847654
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3-(1H-Imidazol-4-yl)propyl2-cyclohexylpropylcarbamate hydrogenmaleate
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C20H31N3O6
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1
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| 1 |
Ki = 447 nM
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CP0536493
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4-(4-methylpiperazin-1-yl)-6-(2-methylprop-1-enyl)-1,3,5-triazin-2-amine
Show/Hide
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C12H20N6
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1
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| 1 |
Ki = 470 nM
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CP0919184
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3-(1H-Imidazol-4-yl)propyl2-cyclohexylbutylcarbamate hydrogenmaleate
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C21H33N3O6
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1
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| 1 |
Ki = 500 nM
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CP0319491
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4-(4-bromophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C14H17BrN6
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1
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| 1 |
Ki = 524 nM
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CP0490651
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4-(4-Methylpiperazin-1-yl)-6-(2-methylpropyl)-1,3,5-triazin-2-amine (10)
Show/Hide
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C12H22N6
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1
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| 1 |
Ki = 529 nM
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CP0528502
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4-N-[(4-methoxyphenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
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C17H24N6O
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1
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| 1 |
Ki = 542 nM
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CP0388257
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4-[(1E,3E)-4-[1-[3-(1H-imidazol-5-yl)propyl]-2,6-dimethylpyridin-1-ium-4-yl]buta-1,3-dienyl]-N,N-dimethylaniline;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
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C29H32F6N4O4
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1
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| 1 |
Ki = 588.84 nM
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CP0422984
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4-[2-(2,2-dimethylpropylamino)pyrimidin-4-yl]piperazine-1-carboximidamide;2,2,2-trifluoroacetic acid
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C18H27F6N7O4
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1
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| 1 |
Ki = 616.6 nM
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CP0955838
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5-(1H-imidazol-4-yl)pentan-1-amine dihydrobromide
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C8H17Br2N3
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1
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| 1 |
Ki = 630.96 nM
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CP0430403
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((R)-1-Methyl-hexyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester; compound with (E)-but-2-enedioic acid
Show/Hide
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C14H25N3O2
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1
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| 1 |
Ki = 636 nM
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CP0447780
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(1-Methyl-pentyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester; compound with (E)-but-2-enedioic acid
Show/Hide
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C13H23N3O2
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1
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| 1 |
Ki = 695 nM
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CP0919479
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(E)-3-(1H-Imidazol-4-yl)propylhex-2-enylcarbamatehydrogen maleate
Show/Hide
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C17H25N3O6
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1
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| 1 |
Ki = 703 nM
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CP0411849
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4-[(E)-2-(3-methylphenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C17H22N6
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1
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| 1 |
Ki = 703 nM
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CP0534051
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6-(4-methylpiperazin-1-yl)-4-N-[(4-phenylphenyl)methyl]pyrimidine-2,4-diamine
Show/Hide
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C22H26N6
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1
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| 1 |
Ki = 716 nM
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CP0542157
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4-butan-2-yl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C12H22N6
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1
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| 1 |
Ki = 725 nM
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CP0430406
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(R,S)-3-(1H-imidazol-4-yl)propyl 2-ethylhexylcarbamate
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C15H27N3O2
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1
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| 1 |
Ki = 779 nM
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CP0440803
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4-(3,4-dichlorophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C14H16Cl2N6
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1
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| 1 |
Ki = 790 nM
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CP0130853
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Imifuramine
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C8H13N3O
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1
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| 1 |
Ki = 794.33 nM
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CP0550759
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4-ethyl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C10H18N6
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1
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| 1 |
Ki = 812 nM
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CP0461089
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4-(3,4-dimethylphenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H22N6
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1
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| 1 |
Ki = 834 nM
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CP0416402
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4-[(1E,3E)-4-[1-[3-[2-(1H-imidazol-5-yl)ethylamino]propyl]-2,6-dimethylpyridin-1-ium-4-yl]buta-1,3-dienyl]-N,N-dimethylaniline;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
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C33H38F9N5O6
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1
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| 1 |
Ki = 933.25 nM
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CP0433900
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4-[(3S)-3-aminopyrrolidin-1-yl]-6-(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C16H17FN6
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1
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| 1 |
Ki = 980 nM
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CP0348117
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5-[(2R,5R)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
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C15H18N2O2
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1
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| 1 |
Ki = 1000 nM
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CP0377318
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1-cyano-2-[[(1R,3R)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-3-(2-phenylsulfanylethyl)guanidine
Show/Hide
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C19H24N6S
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1
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| 1 |
Ki = 1050 nM
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CP0919185
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(E/Z)-3-(1H-Imidazol-4-yl)propylbut-2-enylcarbamate hydrogenmaleate
Show/Hide
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C15H21N3O6
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1
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| 1 |
Ki = 1053 nM
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CP0462563
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4-tert-butyl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C12H22N6
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1
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| 1 |
Ki = 1081 nM
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CP0487007
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4-(4-methylpiperazin-1-yl)-6-phenyl-1,3,5-triazin-2-amine
Show/Hide
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C14H18N6
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1
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| 1 |
Ki = 1099 nM
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CP0411853
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4-[(E)-2-(3-bromophenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H19BrN6
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1
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| 1 |
Ki = 1140 nM
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CP0541968
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4-(3,5-difluorophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C14H16F2N6
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1
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| 1 |
Ki = 1191 nM
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CP0506455
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6-(4-Methylpiperazin-1-yl)-N4-(4-(trifluoromethyl)benzyl)pyrimidine-2,4-diamine
Show/Hide
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C17H21F3N6
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1
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| 1 |
Ki = 1200 nM
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CP0572758
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4-(2-chlorophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C14H17ClN6
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1
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| 1 |
Ki = 1261 nM
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CP0895069
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(E)-3-(1H-Imidazol-4-yl)propylhex-3-enylcarbamatehydrogenmaleate
Show/Hide
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C17H25N3O6
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1
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| 1 |
Ki = 1326 nM
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CP0576946
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4-(4-methylpiperazin-1-yl)-6-pentan-3-yl-1,3,5-triazin-2-amine
Show/Hide
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C13H24N6
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1
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| 1 |
Ki = 1331 nM
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CP0482189
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6-phenyl-4-piperazin-1-yl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C16H18N6
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1
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| 1 |
Ki = 1410 nM
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CP0535488
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4-(4-methyl-1,4-diazepan-1-yl)-6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C18H22N6
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1
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| 1 |
Ki = 1410 nM
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CP0552737
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4-[(1E,3E)-4-[1-[3-[4-(5-fluoro-4-methyl-1H-benzimidazol-2-yl)-3-methylphenoxy]propyl]-2,6-dimethylpyridin-1-ium-4-yl]buta-1,3-dienyl]-N,N-dimethylaniline;2,2,2-trifluoroacetate
Show/Hide
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C39H40F4N4O3
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1
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| 1 |
Ki = 1412.54 nM
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CP0421634
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((S)-1-Methyl-hexyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester; compound with (E)-but-2-enedioic acid
Show/Hide
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C14H25N3O2
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1
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| 1 |
Ki = 1460 nM
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CP0572759
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4-(3-chloro-4-methoxyphenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C15H19ClN6O
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1
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| 1 |
Ki = 1472 nM
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CP0336668
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3-(1H-imidazol-4-yl)propyl 2-cyclopropylethylcarbamate maleate
Show/Hide
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C12H19N3O2
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1
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| 1 |
Ki = 1548.82 nM
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CP0397244
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3-(1H-Imidazol-4-yl)propyl2-cyclohexylethylcarbamate hydrogenmaleate
Show/Hide
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C15H25N3O2
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1
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| 1 |
Ki = 1548.82 nM
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CP0433901
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4-[(3R)-3-aminopyrrolidin-1-yl]-6-(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C16H17FN6
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1
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| 1 |
Ki = 1710 nM
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CP0404438
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N-[(4-methoxyphenyl)methyl]-4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
Show/Hide
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C23H27N5O
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1
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| 1 |
Ki = 1737.8 nM
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CP0447103
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4-(3-methylphenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C15H20N6
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1
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| 1 |
Ki = 1747 nM
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CP0422960
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4-[(E)-2-(3,4-dichlorophenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H18Cl2N6
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1
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| 1 |
Ki = 1780 nM
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CP0443160
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4-(4-methylpiperazin-1-yl)-6-(3,4,5-trifluorophenyl)-1,3,5-triazin-2-amine
Show/Hide
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C14H15F3N6
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1
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| 1 |
Ki = 1787 nM
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CP0527202
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6-[[2-[4-[(E)-2-[2,2-difluoro-12-(1H-pyrrol-2-yl)-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl]ethenyl]phenoxy]acetyl]amino]-N-[3-[4-(5-fluoro-4-methyl-1H-benzimidazol-2-yl)-3-methylphenoxy]propyl]hexanamide
Show/Hide
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C47H47BF3N7O4
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1
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| 1 |
Ki = 1819.7 nM
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CP0422986
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2-N-(2,2-dimethylpropyl)-4-N-piperidin-4-ylpyrimidine-2,4-diamine;2,2,2-trifluoroacetic acid
Show/Hide
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C18H27F6N5O4
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1
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| 1 |
Ki = 1905.46 nM
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CP0416435
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4-[(1E,3E)-4-[1-[2-(1H-imidazol-5-yl)ethyl]-2,6-dimethylpyridin-1-ium-4-yl]buta-1,3-dienyl]-N,N-dimethylaniline;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
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C28H30F6N4O4
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1
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| 1 |
Ki = 1949.84 nM
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CP0376707
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4-(1H-imidazol-5-ylmethyl)-1-methylpiperidine
Show/Hide
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C10H17N3
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1
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| 1 |
Ki = 1995.26 nM
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CP0542717
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6-(4-methylpiperazin-1-yl)-4-N-[(4-propan-2-ylphenyl)methyl]pyrimidine-2,4-diamine
Show/Hide
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C19H28N6
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1
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| 1 |
Ki = 2200 nM
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CP0573273
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4-[(E)-2-(2-methylphenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C17H22N6
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1
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| 1 |
Ki = 2230 nM
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CP0445576
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4-[4-amino-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-yl]benzonitrile
Show/Hide
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C15H17N7
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1
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| 1 |
Ki = 2358 nM
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CP0440802
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4-(4-iodophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C14H17IN6
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1
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| 1 |
Ki = 2391 nM
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CP0406438
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4-(4-methylpiperazin-1-yl)-6-[(E)-2-[3-(trifluoromethyl)phenyl]ethenyl]-1,3,5-triazin-2-amine
Show/Hide
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C17H19F3N6
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1
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| 1 |
Ki = 2450 nM
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CP0452270
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4-(Benzyloxy)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
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C16H21N5O
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1
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| 1 |
Ki = 2500 nM
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CP0182141
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[(2S,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methanamine
Show/Hide
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C8H13N3O
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1
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| 1 |
Ki = 2511.89 nM
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CP0439322
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2-amino-5(2-aminoethyl)-4-methyl-1,3-selenazole
Show/Hide
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C6H11N3Se
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1
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| 1 |
Ki = 2511.89 nM
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CP0468546
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4-[(E)-2-(1H-indol-3-yl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C18H21N7
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1
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| 1 |
Ki = 2525 nM
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CP0411852
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4-(4-methylpiperazin-1-yl)-6-[(E)-2-(3-nitrophenyl)ethenyl]-1,3,5-triazin-2-amine
Show/Hide
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C16H19N7O2
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1
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| 1 |
Ki = 2570 nM
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CP0422982
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N-[(3R)-1-[2-(2,2-dimethylpropylamino)pyrimidin-4-yl]pyrrolidin-3-yl]propanamide;2,2,2-trifluoroacetic acid
Show/Hide
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C18H28F3N5O3
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1
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| 1 |
Ki = 2630.27 nM
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CP0433905
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6-(4-fluorophenyl)-4-(4-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C17H19FN6
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1
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| 1 |
Ki = 2640 nM
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CP0570477
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3-[(E)-2-[4-amino-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-yl]ethenyl]benzonitrile
Show/Hide
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C17H19N7
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1
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| 1 |
Ki = 2640 nM
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CP0559387
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4-methyl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C9H16N6
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1
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| 1 |
Ki = 2664 nM
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CP0433906
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6-methyl-4-piperazin-1-yl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C11H16N6
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1
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| 1 |
Ki = 2670 nM
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CP0422985
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4-[2-(2,2-dimethylpropylamino)pyrimidin-4-yl]-1,4-diazepane-1-carboximidamide;2,2,2-trifluoroacetic acid
Show/Hide
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C19H29F6N7O4
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1
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| 1 |
Ki = 2691.53 nM
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CP0542937
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4-(2-cyclohexylethyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H28N6
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1
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| 1 |
Ki = 2847 nM
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CP0433902
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6-(4-fluorophenyl)-4-(4-methyl-1,4-diazepan-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C18H21FN6
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1
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| 1 |
Ki = 2930 nM
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CP0535491
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6-(4-chlorophenyl)-4-(4-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C17H19ClN6
|
1
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| 1 |
Ki = 3280 nM
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CP0425617
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6-(4-methoxyphenyl)-4-(4-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C18H22N6O
|
1
|
| 1 |
Ki = 3320 nM
|
|
|
|
CP0490921
|
4-N-[(4-tert-butylphenyl)methyl]-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C20H30N6
|
1
|
| 1 |
Ki = 3400 nM
|
|
|
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CP0477260
|
3-(4-chlorobenzyl)-7-(4-methylpiperazin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
Show/Hide
|
C16H18ClN7
|
1
|
| 1 |
Ki = 3500 nM
|
|
|
|
CP0566076
|
4-[(E)-2-(3-fluorophenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H19FN6
|
1
|
| 1 |
Ki = 3520 nM
|
|
|
|
CP0535490
|
6-(4-methylphenyl)-4-(4-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C18H22N6
|
1
|
| 1 |
Ki = 3730 nM
|
|
|
|
CP0411968
|
4-(4-methylpiperazin-1-yl)-6-[(E)-2-naphthalen-2-ylethenyl]-1,3,5-triazin-2-amine
Show/Hide
|
C20H22N6
|
1
|
| 1 |
Ki = 3794 nM
|
|
|
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CP0538963
|
3-(1H-Imidazol-4-yl)propylbut-3-enylcarbamate hydrogenmaleate
Show/Hide
|
C11H17N3O2
|
1
|
| 1 |
Ki = 3801.89 nM
|
|
|
|
CP0376706
|
(2S)-1-(1H-imidazol-5-yl)propan-2-amine
Show/Hide
|
C6H11N3
|
1
|
| 1 |
Ki = 3981.07 nM
|
|
|
|
CP0517987
|
4-(4-ethylpiperazin-1-yl)-6-(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C18H21FN6
|
1
|
| 1 |
Ki = 4070 nM
|
|
|
|
CP0531322
|
4-[(E)-2-(4-chlorophenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H19ClN6
|
1
|
| 1 |
Ki = 4210 nM
|
|
|
|
CP0554860
|
4-(4-methylpiperazin-1-yl)-6-[4-(trifluoromethyl)phenyl]-1,3,5-triazin-2-amine
Show/Hide
|
C15H17F3N6
|
1
|
| 1 |
Ki = 4239 nM
|
|
|
|
CP0392527
|
N-[(4-methoxyphenyl)methyl]-4-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[h]quinazolin-2-amine
Show/Hide
|
C25H29N5O
|
1
|
| 1 |
Ki = 4265.8 nM
|
|
|
|
CP0454159
|
3-(1H-Imidazol-4-yl)propyl2-cyclohexylpropylcarbamate hydrogenmaleate
Show/Hide
|
C16H27N3O2
|
1
|
| 1 |
Ki = 4466.84 nM
|
|
|
|
CP0403382
|
4-[(E)-2-(2-chlorophenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H19ClN6
|
1
|
| 1 |
Ki = 4860 nM
|
|
|
|
CP0076342
|
5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine
Show/Hide
|
C6H11N3S
|
1
|
| 1 |
Ki = 5011.87 nM
|
|
|
|
CP0195311
|
3-(1H-Imidazol-4-yl)propyl2-cyclohexylbutylcarbamate hydrogenmaleate
Show/Hide
|
C17H29N3O2
|
1
|
| 1 |
Ki = 5011.87 nM
|
|
|
|
CP0447104
|
4-(2,6-difluorophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C14H16F2N6
|
1
|
| 1 |
Ki = 5077 nM
|
|
|
|
CP0483635
|
3-[4-amino-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-yl]benzonitrile
Show/Hide
|
C15H17N7
|
1
|
| 1 |
Ki = 5161 nM
|
|
|
|
CP0406439
|
4-(4-methylpiperazin-1-yl)-6-[(E)-2-phenylethenyl]-1,3,5-triazin-2-amine
Show/Hide
|
C16H20N6
|
1
|
| 1 |
Ki = 5210 nM
|
|
|
|
CP0535492
|
4-(4-methylpiperazin-1-yl)-6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C17H20N6
|
1
|
| 1 |
Ki = 5400 nM
|
|
|
|
CP0476256
|
1H-indol-2-yl-[4-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]piperazin-1-yl]methanone
Show/Hide
|
C28H31N5O2
|
1
|
| 1 |
Ki = 5888.44 nM
|
|
|
|
CP0517985
|
6-(4-fluorophenyl)-4-N-[(3S)-pyrrolidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
Show/Hide
|
C16H17FN6
|
1
|
| 1 |
Ki = 5950 nM
|
|
|
|
CP0570922
|
4-(5-chloro-2-methoxyphenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H19ClN6O
|
1
|
| 1 |
Ki = 6007 nM
|
|
|
|
CP0097151
|
[(2R,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methanamine
Show/Hide
|
C8H13N3O
|
1
|
| 1 |
Ki = 6309.57 nM
|
|
|
|
CP0188175
|
6-ethyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine
Show/Hide
|
C13H18N4S
|
1
|
| 1 |
Ki = 6600 nM
|
|
|
|
CP0400195
|
(5-chloro-1H-indol-2-yl)-[4-[2-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl-methylamino]ethyl]piperazin-1-yl]methanone
Show/Hide
|
C31H37ClN6O2
|
1
|
| 1 |
Ki = 6760.83 nM
|
|
|
|
CP0199146
|
3-(1H-imidazol-5-yl)propyl N-[2-(4-chlorophenyl)ethyl]carbamate
Show/Hide
|
C15H18ClN3O2
|
1
|
| 1 |
Ki = 6760.83 nM
|
|
|
|
CP0385343
|
1-(4-methylpiperazin-1-yl)-N-(2-phenylethyl)-5,6-dihydrobenzo[f]quinazolin-3-amine
Show/Hide
|
C25H29N5
|
1
|
| 1 |
Ki = 6760.83 nM
|
|
|
|
CP0375971
|
(E)-3-(1H-Imidazol-4-yl)propylhex-2-enylcarbamatehydrogen maleate
Show/Hide
|
C13H21N3O2
|
1
|
| 1 |
Ki = 7079.46 nM
|
|
|
|
CP0575150
|
4-[(2E)-2-[(2E,4E)-5-[1-[6-[3-[4-(5-fluoro-4-methyl-1H-benzimidazol-2-yl)-3-methylphenoxy]propylamino]-6-oxohexyl]-3,3-dimethylindol-1-ium-2-yl]penta-2,4-dienylidene]-3,3-dimethylindol-1-yl]butane-1-sulfonate
Show/Hide
|
C53H62FN5O5S
|
1
|
| 1 |
Ki = 7079.46 nM
|
|
|
|
CP0433904
|
4-[2-amino-4-(4-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]benzonitrile
Show/Hide
|
C18H19N7
|
1
|
| 1 |
Ki = 7320 nM
|
|
|
|
CP0468977
|
4-Benzyl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine (13)
Show/Hide
|
C15H20N6
|
1
|
| 1 |
Ki = 7499 nM
|
|
|
|
CP0542029
|
1,3-bis(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[f]quinazoline
Show/Hide
|
C22H30N6
|
1
|
| 1 |
Ki = 7762.47 nM
|
|
|
|
CP0099909
|
1-cyano-3-[[(2R,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
|
C11H16N6O
|
1
|
| 1 |
Ki = 7943.28 nM
|
|
|
|
CP0040184
|
1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-1,3-benzodiazol-2-amine
Show/Hide
|
C28H31FN4O
|
1
|
| 1 |
Ki = 7943.28 nM
|
|
|
|
CP0542715
|
9-Benzyl-6-(4-methylpiperazin-1-yl)-9H-purin-2-amine
Show/Hide
|
C17H21N7
|
1
|
| 1 |
Ki = 8100 nM
|
|
|
|
CP0476589
|
7-butyl-4-piperazin-1-ylpyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C14H22N6
|
1
|
| 1 |
Ki = 8130 nM
|
|
|
|
CP0433903
|
4-(4-methyl-1,4-diazepan-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C12H18N6
|
1
|
| 1 |
Ki = 8720 nM
|
|
|
|
CP0535489
|
6-(4-bromophenyl)-4-(4-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C17H19BrN6
|
1
|
| 1 |
Ki = 8990 nM
|
|
|
|
CP0385107
|
4-[(E)-2-(2,4-dichlorophenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H18Cl2N6
|
1
|
| 1 |
Ki = 9040 nM
|
|
|
|
CP0401124
|
4-(4-methylpiperazin-1-yl)-N-(2-phenylethyl)-5,6-dihydrobenzo[h]quinazolin-2-amine
Show/Hide
|
C25H29N5
|
1
|
| 1 |
Ki = 9120.11 nM
|
|
|
|
CP0411110
|
5,5-diphenyl-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]imidazolidine-2,4-dione
Show/Hide
|
C30H33N3O3
|
1
|
| 1 |
Ki = 9332.54 nM
|
|
|
|
CP0456894
|
4-(4-methylpiperazin-1-yl)-6-phenyl-N-(2-phenylethyl)pyrimidin-2-amine
Show/Hide
|
C23H27N5
|
1
|
| 1 |
Ki = 9772.37 nM
|
|
|
|
CP0381527
|
1-[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]-N,N-dimethylmethanamine
Show/Hide
|
C25H31N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391962
|
1-(2-methoxyphenyl)-4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]piperazine
Show/Hide
|
C34H40N4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0413872
|
1-(2-methoxyphenyl)-4-[[3-[(4-methylpiperazin-1-yl)methyl]azulen-1-yl]methyl]piperazine
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0419187
|
[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methanol
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0428802
|
4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]morpholine
Show/Hide
|
C27H33N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0488643
|
1-(2-methoxyphenyl)-4-[[3-(piperidin-1-ylmethyl)azulen-1-yl]methyl]piperazine
Show/Hide
|
C28H35N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0119048
|
1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine
Show/Hide
|
C17H26ClNO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0424192
|
4-[4-(2-aminoethyl)piperazin-1-yl]-N-(2,2-dimethylpropyl)pyrimidin-2-amine;2,2,2-trifluoroacetic acid
Show/Hide
|
C21H31F9N6O6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0476577
|
2-N-(2,2-dimethylpropyl)-4-N-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]pyrimidine-2,4-diamine;2,2,2-trifluoroacetic acid
Show/Hide
|
C20H28F6N6O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391412
|
7-(2-morpholin-4-ylethyl)-4-(4-morpholin-4-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C21H33N7O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391415
|
4-[2-[4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]ethyl]morpholine
Show/Hide
|
C22H34N6O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0397748
|
4-[1-[2-chloro-7-(2-morpholin-4-ylethyl)pyrrolo[2,3-d]pyrimidin-4-yl]piperidin-4-yl]morpholine
Show/Hide
|
C21H31ClN6O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0397749
|
4-[1-[7-(2-morpholin-4-ylethyl)pyrrolo[2,3-d]pyrimidin-4-yl]piperidin-4-yl]morpholine
Show/Hide
|
C21H32N6O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435627
|
2-chloro-7-[(4-chlorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H27Cl2N5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435629
|
7-(2-morpholin-4-ylethyl)-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C22H35N7O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435630
|
2-chloro-7-[(4-fluorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H27ClFN5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0444572
|
4-[[4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methyl]benzonitrile
Show/Hide
|
C24H28N6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0470493
|
4-[2-[2-chloro-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]ethyl]morpholine
Show/Hide
|
C22H33ClN6O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0470494
|
7-[(4-fluorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H28FN5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0477179
|
2-chloro-7-[(2,6-dichlorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H26Cl3N5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0520073
|
4-[[2-chloro-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methyl]benzonitrile
Show/Hide
|
C24H27ClN6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0551447
|
7-[(4-chlorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H28ClN5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0575410
|
7-[(2,6-dichlorophenyl)methyl]-4-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[2,3-d]pyrimidine
Show/Hide
|
C23H27Cl2N5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0415459
|
4-(methoxymethyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C10H18N6O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0430106
|
4-(3-cyclohexylpropyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C17H30N6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0544075
|
2-amino-4-phenyl-8-(3-piperidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0544077
|
4-phenyl-8-(3-pyrrolidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0482186
|
6-(4-fluorophenyl)-N,N-dimethyl-4-(4-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C19H23FN6
|
1
|
| 1 |
Ki = 10450 nM
|
|
|
|
CP0523667
|
[4-[2-[4-[[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C34H38FN7O
|
1
|
| 1 |
Ki = 10471.29 nM
|
|
|
|
CP0541969
|
4-(3,5-dimethylphenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H22N6
|
1
|
| 1 |
Ki = 10567 nM
|
|
|
|
CP0468338
|
N-[(4-fluorophenyl)methyl]-4-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[h]quinazolin-2-amine
Show/Hide
|
C24H26FN5
|
1
|
| 1 |
Ki = 10964.78 nM
|
|
|
|
CP0122622
|
5-[(2S,5R)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
|
C15H18N2O2
|
1
|
| 1 |
Ki = 12589.25 nM
|
|
|
|
CP0154610
|
[(2S,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methanamine
Show/Hide
|
C8H13N3O
|
1
|
| 1 |
Ki = 12589.25 nM
|
|
|
|
CP0087268
|
(E)-3-(1H-Imidazol-4-yl)propylhex-3-enylcarbamatehydrogenmaleate
Show/Hide
|
C13H21N3O2
|
1
|
| 1 |
Ki = 13182.57 nM
|
|
|
|
CP0542716
|
4-(Benzylthio)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C16H21N5S
|
1
|
| 1 |
Ki = 13700 nM
|
|
|
|
CP0456893
|
N-[(4-methoxyphenyl)methyl]-1-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[f]quinazolin-3-amine
Show/Hide
|
C25H29N5O
|
1
|
| 1 |
Ki = 13803.84 nM
|
|
|
|
CP0399983
|
[5-[1-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl-methylamino]propan-2-ylamino]-1H-indol-2-yl]-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C33H43N7O2
|
1
|
| 1 |
Ki = 14125.38 nM
|
|
|
|
CP0477261
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9-benzyl-6-(4-methylpiperazin-1-yl)-9H-purine
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C17H20N6
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1
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| 1 |
Ki = 14300 nM
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CP0531384
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N-benzyl-2-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[h]quinazolin-4-amine
Show/Hide
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C24H27N5
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1
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| 1 |
Ki = 14454.4 nM
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CP0468339
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2-(4-methylpiperazin-1-yl)-N-(2-phenylethyl)-5,6-dihydrobenzo[h]quinazolin-4-amine
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C25H29N5
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1
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| 1 |
Ki = 15135.61 nM
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CP0528503
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6-(4-Methylpiperazin-1-yl)-9H-purin-2-amine
Show/Hide
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C10H15N7
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1
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| 1 |
Ki = 15600 nM
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CP0439979
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(5-chloro-1H-indol-2-yl)-[4-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]piperazin-1-yl]methanone
Show/Hide
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C28H30ClN5O2
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1
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| 1 |
Ki = 15848.93 nM
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CP0087267
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3-(1H-imidazol-5-yl)propyl N-[2-(2-chlorophenoxy)ethyl]carbamate
Show/Hide
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C15H18ClN3O3
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1
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| 1 |
Ki = 16218.1 nM
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CP0400194
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[4-(2-benzhydryloxyethyl)piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
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C28H29N3O2
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1
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| 1 |
Ki = 17782.79 nM
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CP0412118
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6-(4-methylpiperazin-1-yl)-9Hpurine
Show/Hide
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C10H14N6
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1
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| 1 |
Ki = 18400 nM
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CP0468340
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N-[[3-(4-chlorophenyl)-4-methoxyphenyl]methyl]-2-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[h]quinazolin-4-amine
Show/Hide
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C31H32ClN5O
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1
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| 1 |
Ki = 19498.45 nM
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CP0195654
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1-cyano-3-[[(2S,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
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C11H16N6O
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1
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| 1 |
Ki = 19952.62 nM
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CP0309840
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5-[(2S,5S)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
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C15H18N2O2
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1
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| 1 |
Ki = 19952.62 nM
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CP0490419
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N-[(4-methylphenyl)methyl]-4-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[h]quinazolin-2-amine
Show/Hide
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C25H29N5
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1
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| 1 |
Ki = 19952.62 nM
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CP0442834
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1-[3-[4-(3,5-dimethyl-1,2,4-triazol-4-yl)phenoxy]propyl]piperidine
Show/Hide
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C18H26N4O
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1
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| 1 |
Ki = 20417.38 nM
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CP0506688
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1H-benzimidazol-2-yl-[4-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]piperazin-1-yl]methanone
Show/Hide
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C27H30N6O2
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1
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| 1 |
Ki = 22387.21 nM
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CP0392413
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7-benzyl-4-piperazin-1-ylpyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C17H20N6
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1
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| 1 |
Ki = 25220 nM
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CP0456859
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N-benzyl-1-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[f]quinazolin-3-amine
Show/Hide
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C24H27N5
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1
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| 1 |
Ki = 26302.68 nM
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CP0524540
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1H-indol-2-yl-[(3S)-3-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethylamino]pyrrolidin-1-yl]methanone
Show/Hide
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C28H31N5O2
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1
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| 1 |
Ki = 27542.29 nM
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CP0388255
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7-[(E)-2-[1-[3-[4-(5-fluoro-4-methyl-1H-benzimidazol-2-yl)-3-methylphenoxy]propyl]-2,6-dimethylpyridin-1-ium-4-yl]ethenyl]-1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-triene;2,2,2-trifluoroacetate
Show/Hide
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C41H42F4N4O3
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1
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| 1 |
Ki = 28183.83 nM
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CP0566075
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4-(4-methylpiperazin-1-yl)-6-[(E)-2-naphthalen-1-ylethenyl]-1,3,5-triazin-2-amine
Show/Hide
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C20H22N6
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1
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| 1 |
Ki = 29985 nM
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CP0490418
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N-benzyl-2-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-4-amine
Show/Hide
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C22H25N5
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1
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| 1 |
Ki = 31622.78 nM
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CP0490920
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1-((1-Benzyl-1H-1,2,3-triazol-4-yl)methyl)-4-methylpiperazine
Show/Hide
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C15H21N5
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1
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| 1 |
Ki = 35000 nM
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CP0499265
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6-(3,4-dichlorophenyl)-4-(4-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C17H18Cl2N6
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1
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| 1 |
Ki = 36120 nM
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CP0531385
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2-(4-methylpiperazin-1-yl)-6-phenyl-N-(2-phenylethyl)pyrimidin-4-amine
Show/Hide
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C23H27N5
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1
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| 1 |
Ki = 36307.81 nM
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CP0476590
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7-methyl-4-piperazin-1-ylpyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C11H16N6
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1
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| 1 |
Ki = 36350 nM
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CP0422959
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4-[(E)-2-(4-methylphenyl)ethenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C17H22N6
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1
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| 1 |
Ki = 37400 nM
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CP0199147
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3-(1H-imidazol-4-yl)propyl pent-4-enylcarbamate hydrogenmalate
Show/Hide
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C12H19N3O2
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1
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| 1 |
Ki = 41686.94 nM
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CP0056899
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(2-Benzhydryloxy-ethyl)-dimethyl-amine
Show/Hide
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C17H21NO
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1
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| 1 |
Ki = 42657.95 nM
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CP0470618
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6-(4-fluorophenyl)-7-methyl-4-piperazin-1-ylpyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C17H19FN6
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1
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| 1 |
Ki = 44150 nM
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CP0497481
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4-piperazin-1-yl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C10H14N6
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1
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| 1 |
Ki = 45920 nM
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CP0476591
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6-(4-fluorophenyl)-4-(4-propan-2-ylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C19H23FN6
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1
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| 1 |
Ki = 48010 nM
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CP0554862
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4-[4-(dimethylamino)phenyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H23N7
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1
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| 1 |
Ki = 64490 nM
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CP0535487
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6-(4-fluorophenyl)-7-methyl-4-(4-methylpiperazin-1-yl)pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C18H21FN6
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1
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| 1 |
Ki = 67870 nM
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CP0401125
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N-[(4-methoxyphenyl)methyl]-2-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-4-amine
Show/Hide
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C23H27N5O
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1
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| 1 |
Ki = 72443.6 nM
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CP0443294
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6-(4-fluorophenyl)-N,7-dimethyl-4-(4-methylpiperazin-1-yl)pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
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C19H23FN6
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1
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| 1 |
Ki > 100000 nM
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CP0375970
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3-(1H-imidazol-5-yl)propyl N-(4-phenoxybutyl)carbamate
Show/Hide
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C17H23N3O3
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1
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| 1 |
Ki > 100000 nM
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CP0397243
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3-(1H-imidazol-5-yl)propyl N-(3-phenoxypropyl)carbamate
Show/Hide
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C16H21N3O3
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1
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| 1 |
Ki > 100000 nM
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CP0379917
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1-(4-chlorophenyl)-4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]piperazine
Show/Hide
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C33H37ClN4O
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1
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| 1 |
Ki > 1000 nM
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