Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-cyano-2-[4-(1H-imidazol-5-yl)butyl]-3-(2-phenylsulfanylethyl)guanidine
    Show/Hide
 PubChem ID
CID: 44478385
SID: 85762083
Canonical SMILES
N#CNC(NCCSc1ccccc1)=NCCCCc1cnc[nH]1
    Show/Hide
Compound Formula C17H22N6S
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  5
1
Activity >= 10 nM
   TI
   LI
   LO
   TS
2
EC50 = 33.88 nM
   TI
   LI
   LO
   TS
3
EC50 = 37 nM
   TI
   LI
   LO
   TS
4
EC50 = 37.15 nM
   TI
   LI
   LO
   TS
5
Ki = 57.54 nM
   TI
   LI
   LO
   TS