| Compound ID |
Compound Name |
Compound Formula |
|
CP0910722
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-pyrazol-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide dihydrochloride
Show/Hide
|
C34H34Cl6N6O4
|
1
|
| 1 |
IC50 = 0.17 nM
|
|
|
|
CP0916697
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-pyrazol-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide hydrochloride
Show/Hide
|
C35H33Cl3N6O4
|
1
|
| 1 |
IC50 = 0.18 nM
|
|
|
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CP0902835
|
4-[3-({[2,4-Dichloro-3-(4-imidazol-1-yl-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-ureido]-N-pyridin-4-yl-benzamide; trihydrochloride
Show/Hide
|
C36H31Cl3N8O4
|
1
|
| 1 |
IC50 = 0.23 nM
|
|
|
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CP0918770
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-[1,2,4]triazol-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide dihydrochloride
Show/Hide
|
C33H33Cl6N7O4
|
1
|
| 1 |
IC50 = 0.23 nM
|
|
|
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CP0874688
|
4-[(E)-2-({1-[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-1H-pyrrol-2-ylmethyl}-carbamoyl)-vinyl]-N-methyl-benzamide hydrochloride
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|
C33H29Cl3N4O3
|
1
|
| 1 |
IC50 = 0.26 nM
|
|
|
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CP0859312
|
4-[(E)-2-({1-[2,4-Dichloro-3-(4-imidazol-1-yl-2-methyl-quinolin-8-yloxymethyl)-phenyl]-1H-pyrrol-2-ylmethyl}-carbamoyl)-vinyl]-N,N-dimethyl-benzamide dihydrochloride
Show/Hide
|
C37H36Cl6N6O3
|
1
|
| 1 |
IC50 = 0.26 nM
|
|
|
|
CP0916369
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-[1,2,3]triazol-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide hydrochloride
Show/Hide
|
C34H32Cl3N7O4
|
1
|
| 1 |
IC50 = 0.28 nM
|
|
|
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CP0932655
|
4-{(E)-2-[({[2,4-Dichloro-3-(4-imidazol-1-yl-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide dihydrochloride
Show/Hide
|
C34H34Cl6N6O4
|
1
|
| 1 |
IC50 = 0.28 nM
|
|
|
|
CP0860790
|
4-{(E)-2-[({[2,4-Dichloro-3-(4-imidazol-1-yl-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide dihydrochloride
Show/Hide
|
C35H36Cl6N6O4
|
1
|
| 1 |
IC50 = 0.35 nM
|
|
|
|
CP0357474
|
5-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-pyridine-2-carboxylic acid ((E)-2-pyridin-4-yl-vinyl)-amide
Show/Hide
|
C42H35Cl2N7O5
|
1
|
| 1 |
IC50 = 0.36 nM
|
|
|
|
CP0914678
|
3-(6-Acetylamino-pyridin-3-yl)-N-{1-[2,4-bis-acetylamino-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-1H-pyrrol-2-ylmethyl}-acrylamide
Show/Hide
|
C36H37Cl2N7O5
|
1
|
| 1 |
IC50 = 0.37 nM
|
|
|
|
CP0230250
|
4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-pyridin-4-yl-benzamide
Show/Hide
|
C41H34Cl2N6O5
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0874405
|
4-(2-{[(E)-3-(4-Dimethylcarbamoyl-phenyl)-acryloylamino]-methyl}-pyrrol-1-yl)-N*1*,N*1*,N*3*,N*3*-tetramethyl-2-(2-methyl-quinolin-8-yloxymethyl)-isophthalamide hydrochloride
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|
C40H43ClN6O5
|
1
|
| 1 |
IC50 = 0.41 nM
|
|
|
|
CP0935598
|
(E)-N-{1-[3-(2-Methyl-quinolin-8-yloxymethyl)-2,4-bis-(2-oxo-pyrrolidin-1-yl)-phenyl]-1H-pyrrol-2-ylmethyl}-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide hydrochloride
Show/Hide
|
C43H43ClN6O5
|
1
|
| 1 |
IC50 = 0.41 nM
|
|
|
|
CP0304790
|
4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide
Show/Hide
|
C37H33Cl2N5O5
|
1
|
| 1 |
IC50 = 0.41 nM
|
|
|
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CP0860696
|
4-{(E)-2-[({[2,4-Dichloro-3-(4-imidazol-1-yl-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-4-yl-benzamide; trihydrochloride
Show/Hide
|
C38H32Cl3N7O4
|
1
|
| 1 |
IC50 = 0.42 nM
|
|
|
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CP0889421
|
4-[(E)-2-({1-[2,4-Dichloro-3-(4-imidazol-1-yl-2-methyl-quinolin-8-yloxymethyl)-phenyl]-1H-pyrrol-2-ylmethyl}-carbamoyl)-vinyl]-N-pyridin-2-ylmethyl-benzamide; trihydrochloride
Show/Hide
|
C41H34Cl3N7O3
|
1
|
| 1 |
IC50 = 0.43 nM
|
|
|
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CP0919158
|
N-(4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-phenyl)-isonicotinamide; Trihydrochloride
Show/Hide
|
C37H35Cl3N6O4
|
1
|
| 1 |
IC50 = 0.47 nM
|
|
|
|
CP0404246
|
Firazyr
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|
C59H89N19O13S
|
3
|
| 1 |
IC50 = 0.49 nM
|
|
|
| 2 |
Ki = 0.06 nM
|
|
|
| 3 |
Ki = 0.064 nM
|
|
|
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CP0905326
|
Arg-Arg-Pro-Hyp-Gly-Thi-Cys-Tic-Oic-Arg
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|
C59H83N19O12S2
|
1
|
| 1 |
IC50 = 0.49 nM
|
|
|
|
CP0392561
|
(E)-N-({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[6-((E)-2-pyridin-4-yl-vinyl)-pyridin-3-yl]-acrylamide
Show/Hide
|
C35H29Cl2N5O3
|
1
|
| 1 |
IC50 = 0.51 nM
|
|
|
|
CP0467095
|
(E)-N-({Methyl-[3-(2-methyl-quinolin-8-yloxymethyl)-2,4-bis-((E)-2-pyridin-4-yl-vinyl)-phenyl]-carbamoyl}-methyl)-3-[6-((E)-2-pyridin-4-yl-vinyl)-pyridin-3-yl]-acrylamide
Show/Hide
|
C49H41N7O3
|
1
|
| 1 |
IC50 = 0.51 nM
|
|
|
|
CP0897106
|
N-{1-[3-(2-Methyl-quinolin-8-yloxymethyl)-2,4-bis-(2-pyridin-4-yl-vinyl)-phenyl]-1H-pyrrol-2-ylmethyl}-3-[6-(2-pyridin-4-yl-vinyl)-pyridin-3-yl]-acrylamide
Show/Hide
|
C51H44Cl3N7O2
|
1
|
| 1 |
IC50 = 0.52 nM
|
|
|
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CP0878952
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-piperidin-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-4-yl-benzamide; Trihydrochloride
Show/Hide
|
C40H39Cl3N6O4
|
1
|
| 1 |
IC50 = 0.52 nM
|
|
|
|
CP0399449
|
N-[4-[(E)-3-[[2-[2,4-dichloro-N-methyl-3-[[2-methyl-4-(pyridin-2-ylmethoxy)quinolin-8-yl]oxymethyl]anilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]phenyl]pyridine-4-carboxamide
Show/Hide
|
C41H34Cl2N6O5
|
1
|
| 1 |
IC50 = 0.56 nM
|
|
|
|
CP0946870
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-morpholin-4-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-4-yl-benzamide; Trihydrochloride
Show/Hide
|
C39H37Cl3N6O5
|
1
|
| 1 |
IC50 = 0.64 nM
|
|
|
|
CP0335342
|
(E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichloro-3-(2-methoxy-1-pyridin-2-ylmethyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide
Show/Hide
|
C34H31Cl2N7O5
|
1
|
| 1 |
IC50 = 0.68 nM
|
|
|
|
CP0135118
|
4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-2-methoxy-N-methyl-benzamide
Show/Hide
|
C38H35Cl2N5O6
|
1
|
| 1 |
IC50 = 0.69 nM
|
|
|
|
CP0918917
|
4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-4-yl-benzamide; Trihydrochloride
Show/Hide
|
C37H35Cl3N6O4
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0915790
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-piperidin-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide; Dihydrochloride
Show/Hide
|
C37H43Cl6N5O4
|
1
|
| 1 |
IC50 = 0.76 nM
|
|
|
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CP0293423
|
(E)-N-[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide
Show/Hide
|
C39H35Cl2N5O5
|
1
|
| 1 |
IC50 = 0.83 nM
|
|
|
|
CP0885928
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-morpholin-4-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide; Dihydrochloride
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|
C36H41Cl6N5O5
|
1
|
| 1 |
IC50 = 0.88 nM
|
|
|
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CP0306104
|
ethyl 2-[4-[[3-[[2-[[(E)-3-(6-acetamidopyridin-3-yl)prop-2-enoyl]amino]acetyl]-methylamino]-2,6-dichlorophenyl]methoxy]-2-methoxybenzimidazol-1-yl]acetate
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|
C32H32Cl2N6O7
|
1
|
| 1 |
IC50 = 0.91 nM
|
|
|
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CP0902376
|
N-(4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-morpholin-4-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-phenyl)-isonicotinamide; Trihydrochloride
Show/Hide
|
C39H37Cl3N6O5
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
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CP0916074
|
4-{(E)-2-[({[2,4-Dimethyl-3-(2-methyl-4-phenyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
|
C39H39ClN4O4
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
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CP0847066
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
|
C31H29Cl3N4O4
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0855339
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-piperidin-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; Dihydrochloride
Show/Hide
|
C36H41Cl6N5O4
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0878976
|
5-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-morpholin-4-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid methylamide; Trihydrochloride
Show/Hide
|
C34H35Cl3N6O5
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0403065
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; hydrochloride
Show/Hide
|
C31H28Cl2N4O4
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0918860
|
(E)-N-({[2,4-Dichloro-3-(2-methyl-4-piperidin-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide; Dihydrochloride
Show/Hide
|
C38H43Cl6N5O4
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
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CP0150906
|
(E)-3-(6-Acetylamino-pyridin-3-yl)-N-[({2,4-dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-acrylamide
Show/Hide
|
C36H32Cl2N6O5
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
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CP0373173
|
(E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide
Show/Hide
|
C30H27Cl2N5O4
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
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CP0245429
|
5-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-pyridine-2-carboxylic acid methylamide
Show/Hide
|
C36H32Cl2N6O5
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
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CP0267244
|
4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N,N-dimethyl-benzamide
Show/Hide
|
C38H35Cl2N5O5
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
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CP0901926
|
N*1*,N*3*-Dimethyl-4-(2-{[3-(6-methylcarbamoyl-pyridin-3-yl)-acryloylamino]-methyl}-pyrrol-1-yl)-2-(2-methyl-quinolin-8-yloxymethyl)-isophthalamide
Show/Hide
|
C36H37Cl2N7O5
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
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CP0892952
|
N-(4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-piperidin-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-phenyl)-isonicotinamide; Trihydrochloride
Show/Hide
|
C40H39Cl3N6O4
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
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CP0895617
|
5-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid methylamide; Trihydrochloride
Show/Hide
|
C32H33Cl3N6O4
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
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CP0912576
|
4-{2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-4-yl-benzamide dihydrochloride
Show/Hide
|
C35H31Cl4N5O4
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
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CP0402257
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(E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichloro-3-(2-methyl-4-morpholin-4-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide
Show/Hide
|
C34H34Cl2N6O5
|
1
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| 1 |
IC50 = 1.8 nM
|
|
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CP0869698
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(E)-N-({[2,4-Dichloro-3-(2-methyl-4-morpholin-4-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide; Dihydrochloride
Show/Hide
|
C37H41Cl6N5O5
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
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CP0941738
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(E)-3-(4-Acetylamino-phenyl)-N-({[2,4-dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide hydrochloride
Show/Hide
|
C31H29Cl3N4O4
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
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CP0957143
|
4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-2-methoxy-N-methyl-benzamide; Dihydrochloride
Show/Hide
|
C34H39Cl6N5O5
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
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CP0887400
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4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide; Dihydrochloride
Show/Hide
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C34H37Cl4N5O4
|
1
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| 1 |
IC50 = 2.1 nM
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|
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CP0534108
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4-{(E)-2-[({[2,4-Dichloro-3-(2-methoxy-1-methyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C30H29Cl2N5O5
|
1
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| 1 |
IC50 = 2.2 nM
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|
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CP0943579
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4-{(E)-2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide hydrochloride
Show/Hide
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C30H29BrCl3N5O4
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
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CP0921609
|
3-[3-({[2,4-Dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-ureido]-N-pyridin-4-yl-benzamide; Trihydrochloride
Show/Hide
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C35H34Cl3N7O4
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
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CP0212766
|
(E)-N-[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-3-[6-(2-pyridin-4-yl-acetylamino)-pyridin-3-yl]-acrylamide
Show/Hide
|
C41H35Cl2N7O5
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
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CP0847286
|
5-{2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid pyridin-4-ylamide; trihydrochloride
Show/Hide
|
C34H31Cl5N6O4
|
1
|
| 1 |
IC50 = 2.5 nM
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|
|
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CP0894257
|
(E)-3-(4-Acetylamino-phenyl)-N-({[2,4-dichloro-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide hydrochloride
Show/Hide
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C30H28Cl3N5O4
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
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CP0957195
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-piperidin-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-2-ylmethyl-benzamide; Trihydrochloride
Show/Hide
|
C41H41Cl3N6O4
|
1
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| 1 |
IC50 = 2.5 nM
|
|
|
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CP0321601
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(E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[3-(1-benzyl-2-methoxy-1H-benzoimidazol-4-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-acrylamide
Show/Hide
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C35H32Cl2N6O5
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1
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| 1 |
IC50 = 2.5 nM
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CP0512120
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4-((E)-2-{[2',4'-Dimethyl-3'-(2-methyl-quinolin-8-yloxymethyl)-biphenyl-2-ylmethyl]-carbamoyl}-vinyl)-N-methyl-benzamide
Show/Hide
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C37H35N3O3
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1
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| 1 |
IC50 = 2.6 nM
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CP0785209
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{8-[2,6-Dichloro-3-(methyl-{2-[(E)-3-(4-methylcarbamoyl-phenyl)-acryloylamino]-acetyl}-amino)-benzyloxy]-2-methyl-quinolin-4-yloxy}-acetic acid ethyl ester hydrochloride
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C35H35Cl3N4O7
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1
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| 1 |
IC50 = 2.6 nM
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CP0869938
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4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-morpholin-4-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; Dihydrochloride
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C35H39Cl6N5O5
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1
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| 1 |
IC50 = 2.7 nM
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CP0946244
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N-(5-{2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridin-2-yl)-isonicotinamide; trihydrochloride
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C34H31Cl5N6O4
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1
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| 1 |
IC50 = 2.8 nM
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CP0889520
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(E)-N-({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide hydrochloride
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C33H31Cl3N4O4
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1
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| 1 |
IC50 = 3.2 nM
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CP0914295
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(E)-N-({Methyl-[3-(2-methyl-quinolin-8-yloxymethyl)-2,4-bis-(2-oxo-pyrrolidin-1-yl)-phenyl]-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide hydrochloride
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C41H43ClN6O6
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1
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| 1 |
IC50 = 3.2 nM
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CP0862913
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4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; Dihydrochloride
Show/Hide
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C33H35Cl4N5O4
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1
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| 1 |
IC50 = 3.2 nM
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CP0317111
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(E)-3-(6-Acetylamino-pyridin-3-yl)-N-[({2,4-dichloro-3-[2-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazol-4-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-acrylamide
Show/Hide
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C31H32Cl2N6O6
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1
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| 1 |
IC50 = 3.5 nM
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CP0738946
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4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylcarbamoylmethoxy-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C35H36Cl3N5O6
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1
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| 1 |
IC50 = 3.7 nM
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CP0919762
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4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide hydrochloride
Show/Hide
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C32H31Cl3N4O4
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1
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| 1 |
IC50 = 3.9 nM
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CP0950982
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4-({2-[(E)-3-(4-Dimethylcarbamoyl-phenyl)-acryloylamino]-acetyl}-methyl-amino)-N*1*,N*1*,N*3*,N*3*-tetramethyl-2-(2-methyl-quinolin-8-yloxymethyl)-isophthalamide hydrochloride
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C38H43ClN6O6
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1
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| 1 |
IC50 = 3.9 nM
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CP0946906
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5-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid dimethylamide; Dihydrochloride
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C33H38Cl6N6O4
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1
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| 1 |
IC50 = 4 nM
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CP0182960
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(E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichloro-3-(2-methoxy-1-methyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide
Show/Hide
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C29H28Cl2N6O5
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1
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| 1 |
IC50 = 4.2 nM
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CP0957259
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(E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide; Trihydrochloride
Show/Hide
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C32H33Cl3N6O4
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1
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| 1 |
IC50 = 4.2 nM
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CP0900277
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5-{2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid methylamide dihydrochloride
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C30H29Cl4N5O4
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1
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| 1 |
IC50 = 4.6 nM
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CP0907760
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N*1*,N*3*-Dimethyl-4-(methyl-{2-[3-(6-methylcarbamoyl-pyridin-3-yl)-acryloylamino]-acetyl}-amino)-2-(2-methyl-quinolin-8-yloxymethyl)-isophthalamide
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C34H37Cl2N7O6
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1
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| 1 |
IC50 = 4.6 nM
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CP0895137
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4-{(E)-2-[({[2,4-Dimethyl-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C33H35ClN4O4
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1
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| 1 |
IC50 = 4.8 nM
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CP0453533
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4-{(E)-2-[({[2,4-Dimethyl-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; hydrochloride
Show/Hide
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C33H34N4O4
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1
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| 1 |
IC50 = 4.8 nM
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CP0898595
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(E)-3-(4-Acetylamino-3-methyl-phenyl)-N-({[2,4-dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide; Dihydrochloride
Show/Hide
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C34H39Cl6N5O4
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1
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| 1 |
IC50 = 4.8 nM
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CP0885377
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4-{(E)-2-[({[2,4-Dichloro-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C30H28Cl3N5O4
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1
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| 1 |
IC50 = 5.2 nM
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CP0892998
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N-({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[6-(2-oxo-pyrrolidin-1-yl)-pyridin-3-yl]-acrylamide dihydrochloride
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C32H31Cl4N5O4
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1
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| 1 |
IC50 = 5.2 nM
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CP0492313
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4-[(E)-2-({3-[2,4-Dimethyl-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-thiophen-2-ylmethyl}-carbamoyl)-vinyl]-N-methyl-benzamide
Show/Hide
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C35H33N3O3S
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1
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| 1 |
IC50 = 5.8 nM
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CP0922549
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4-{(E)-2-[({[2,4-Dichloro-3-(4-dimethylamino-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-2-ylmethyl-benzamide; Trihydrochloride
Show/Hide
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C38H37Cl3N6O4
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1
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| 1 |
IC50 = 5.9 nM
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CP0372265
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4-{(E)-2-[({[3-(2-Methoxy-1-methyl-1H-benzoimidazol-4-yloxymethyl)-2,4-dimethyl-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C32H35N5O5
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1
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| 1 |
IC50 = 7.2 nM
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CP0850151
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4-{2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-3-yl-benzamide dihydrochloride
Show/Hide
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C35H31Cl4N5O4
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1
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| 1 |
IC50 = 7.5 nM
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CP0773582
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4-{(E)-2-[({[2,4-Dichloro-3-(4-methoxy-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C32H31Cl3N4O5
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1
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| 1 |
IC50 = 8.1 nM
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CP0488931
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(E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[3-(2-methoxy-1-methyl-1H-benzoimidazol-4-yloxymethyl)-2,4-dimethyl-phenyl]-methyl-carbamoyl}-methyl)-acrylamide
Show/Hide
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C31H34N6O5
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1
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| 1 |
IC50 = 8.5 nM
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CP0942235
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3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dimethyl-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide dihydrochloride
Show/Hide
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C32H35Cl2N5O4
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1
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| 1 |
IC50 = 8.5 nM
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CP0885378
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4-{(E)-2-[({[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C29H27BrCl3N5O4
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1
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| 1 |
IC50 = 9 nM
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CP0892997
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(E)-N-({[2,4-Dimethyl-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide hydrochloride
Show/Hide
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C35H37ClN4O4
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1
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| 1 |
IC50 = 9.3 nM
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CP0451454
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4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-phenyl-benzamide
Show/Hide
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C36H30Cl2N4O4
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1
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| 1 |
IC50 = 11 nM
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CP0691220
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4-{(E)-2-[({[2,4-Dichloro-3-(4-isopropoxy-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C34H35Cl3N4O5
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1
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| 1 |
IC50 = 13 nM
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CP0449168
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4-{(E)-2-[({[2,4-Dichloro-3-(2-methoxy-1-methyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide
Show/Hide
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C31H31Cl2N5O5
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1
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| 1 |
IC50 = 14 nM
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CP0384195
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4-((E)-2-{(Z)-3-[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-allylcarbamoyl}-vinyl)-N-methyl-benzamide
Show/Hide
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C31H27Cl2N3O3
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1
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| 1 |
IC50 = 14 nM
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CP0128813
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(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,4R)-1-[(2S)-1-[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Show/Hide
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C60H87N19O13
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1
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| 1 |
IC50 = 14 nM
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CP0461162
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4-{(E)-2-[({[2,4-Dimethyl-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C32H33N5O4
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1
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| 1 |
IC50 = 17 nM
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CP0881767
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4-[(E)-2-({[(3-{4-[Bis-(2-methoxy-ethyl)-amino]-2-methyl-quinolin-8-yloxymethyl}-2,4-dichloro-phenyl)-methyl-carbamoyl]-methyl}-carbamoyl)-vinyl]-N-methyl-benzamide; Dihydrochloride
Show/Hide
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C37H45Cl6N5O6
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1
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| 1 |
IC50 = 19 nM
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CP0918455
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4-{(E)-2-[({[2,4-Dichloro-3-(2-ethyl-1-methyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C31H32Cl3N5O4
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1
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| 1 |
IC50 = 22 nM
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CP0451624
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(E)-N-({[2,4-Dichloro-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide
Show/Hide
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C32H29Cl2N5O4
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1
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| 1 |
IC50 = 26 nM
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CP0458907
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4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-pyridin-2-yl-benzamide
Show/Hide
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C35H29Cl2N5O4
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1
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| 1 |
IC50 = 30 nM
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CP0837237
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4-{(E)-2-[({[2,4-Dichloro-3-(4-ethoxy-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C33H33Cl3N4O5
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1
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| 1 |
IC50 = 34 nM
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CP0879008
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4-{(E)-2-[({[3-(4-Azepan-1-yl-2-methyl-quinolin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; Dihydrochloride
Show/Hide
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C37H43Cl6N5O4
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1
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| 1 |
IC50 = 37 nM
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CP0893009
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N-({[2,4-Dimethyl-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[6-(2-oxo-pyrrolidin-1-yl)-pyridin-3-yl]-acrylamide dihydrochloride
Show/Hide
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C34H37Cl2N5O4
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1
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| 1 |
IC50 = 39 nM
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CP0895186
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4-((E)-2-{[({2,4-Dichloro-3-[4-(2-methoxy-ethylamino)-2-methyl-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide; Dihydrochloride
Show/Hide
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C34H39Cl6N5O5
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1
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| 1 |
IC50 = 41 nM
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CP0409922
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4-{(E)-2-[({[2,4-Dichloro-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide
Show/Hide
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C31H29Cl2N5O4
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1
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| 1 |
IC50 = 44 nM
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CP0445201
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(E)-N-({[2,4-Dimethyl-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide
Show/Hide
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C34H35N5O4
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1
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| 1 |
IC50 = 46 nM
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CP0402496
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4-{(E)-2-[({[2,4-Dichloro-3-(1-ethyl-2-methyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C31H31Cl2N5O4
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1
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| 1 |
IC50 = 48 nM
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CP0465050
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4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinazolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C30H27Cl2N5O4
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1
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| 1 |
IC50 = 56 nM
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CP0847567
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5-{2-[({[2,4-Dimethyl-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid methylamide dihydrochloride
Show/Hide
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C32H35Cl2N5O4
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1
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| 1 |
IC50 = 58 nM
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CP0755295
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4-{(E)-2-[({[2,4-Dichloro-3-(4-cyclopentyloxy-2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C36H37Cl3N4O5
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1
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| 1 |
IC50 = 61 nM
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CP0392560
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4-{(E)-2-[({[2,4-Dichloro-3-(1,2-dimethyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C30H29Cl2N5O4
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1
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| 1 |
IC50 = 67 nM
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CP0825869
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4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-propoxy-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide hydrochloride
Show/Hide
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C34H35Cl3N4O5
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1
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| 1 |
IC50 = 77 nM
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CP0472190
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4-{(E)-2-[({[2,4-Dimethyl-3-(1-methyl-2-methylsulfanyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C32H35N5O4S
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1
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| 1 |
IC50 = 79 nM
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CP0894584
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4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-pyrrolidin-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; Dihydrochloride
Show/Hide
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C35H39Cl6N5O4
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1
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| 1 |
IC50 = 87 nM
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CP0881004
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4-{(E)-2-[({[3-(2-Acetyl-1-methyl-1H-benzoimidazol-4-yloxymethyl)-2,4-dimethyl-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C33H35N5O5
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1
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| 1 |
IC50 = 94 nM
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CP0931927
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4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(4-methyl-piperazin-1-yl)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide; Dihydrochloride
Show/Hide
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C36H42Cl6N6O4
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1
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| 1 |
IC50 = 98 nM
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CP0503147
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4-{(E)-2-[({[4-Chloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C31H29ClN4O4
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1
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| 1 |
IC50 = 110 nM
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CP0470706
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4-{(E)-2-[({[2,4-Dimethyl-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N,N-dimethyl-benzamide
Show/Hide
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C33H35N5O4
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1
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| 1 |
IC50 = 130 nM
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CP0517897
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(E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dimethyl-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-acrylamide
Show/Hide
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C31H32N6O4
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1
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| 1 |
IC50 = 130 nM
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CP0524326
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4-[(E)-3-[[2-[N,2-dimethyl-3-[(2-methylquinolin-8-yl)oxymethyl]anilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]-N-methylbenzamide
Show/Hide
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C32H32N4O4
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1
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| 1 |
IC50 = 150 nM
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CP0406330
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4-{(E)-2-[({[3-(2-Dimethylamino-1-methyl-1H-benzoimidazol-4-yloxymethyl)-2,4-dimethyl-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C33H38N6O4
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1
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| 1 |
IC50 = 160 nM
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CP0431701
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4-{(E)-2-[({[2,4-Dimethoxy-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C33H34N4O6
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1
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| 1 |
IC50 = 210 nM
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CP0423967
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4-{(E)-2-[({[2,4-Dichloro-3-(2,3-dimethyl-benzofuran-7-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
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C31H29Cl2N3O5
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1
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| 1 |
IC50 = 270 nM
|
|
|
|
CP0931123
|
(E)-N-({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-phenyl-acrylamide hydrochloride
Show/Hide
|
C29H26Cl3N3O3
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0941844
|
N-({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-pyridin-3-yl-acrylamide dihydrochloride
Show/Hide
|
C28H26Cl4N4O3
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0543226
|
5-{(E)-2-[({[2,4-Dimethyl-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-pyridine-2-carboxylic acid methylamide
Show/Hide
|
C31H32N6O4
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0497813
|
4-{(E)-2-[({[2,4-Dimethyl-3-(1-methyl-2-methylamino-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
|
C32H36N6O4
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0437581
|
4-[(E)-3-[[(E)-3-[2,4-dichloro-3-[(2-methylquinolin-8-yl)oxymethyl]phenyl]prop-2-enyl]amino]-3-oxoprop-1-enyl]-N-methylbenzamide
Show/Hide
|
C31H27Cl2N3O3
|
1
|
| 1 |
IC50 = 710 nM
|
|
|
|
CP0440487
|
4-{(E)-2-[({[3-(2-Ethoxy-1-methyl-1H-benzoimidazol-4-yloxymethyl)-2,4-dimethyl-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
|
C33H37N5O5
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0494786
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-benzooxazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
|
C29H26Cl2N4O5
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0511276
|
4-((E)-2-{[({2,4-Dichloro-3-[2-(2,5-dimethyl-pyrrol-1-yl)-pyridin-3-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide
Show/Hide
|
C32H31Cl2N5O4
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0874525
|
4-((E)-2-{[({2,4-Dichloro-3-[4-(2-dimethylamino-ethylamino)-2-methyl-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide; Trihydrochloride
Show/Hide
|
C35H39Cl3N6O4
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0383199
|
4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
|
C30H27Cl2N5O4
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0406360
|
(E)-3-(6-Acetylamino-pyridin-3-yl)-N-{[2,4-dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenylcarbamoyl]-methyl}-acrylamide
Show/Hide
|
C29H25Cl2N5O4
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0488806
|
ethyl 2-[4-[[2,6-dimethyl-3-[methyl-[2-[[(E)-3-[4-(methylcarbamoyl)phenyl]prop-2-enoyl]amino]acetyl]amino]phenyl]methoxy]-1-methylbenzimidazol-2-yl]acetate
Show/Hide
|
C35H39N5O6
|
1
|
| 1 |
IC50 = 8400 nM
|
|
|
|
CP0483071
|
4-{(E)-2-[({[3-(2-Methoxymethyl-1-methyl-1H-benzoimidazol-4-yloxymethyl)-2,4-dimethyl-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
|
C33H37N5O5
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0377942
|
4-{(E)-2-[({[2,4-Dichloro-3-(6-methyl-pyridin-2-ylmethoxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
|
C28H28Cl2N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0537258
|
4-{(E)-2-[2',4'-Dimethyl-3'-(2-methyl-quinolin-8-yloxymethyl)-biphenyl-3-ylcarbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
|
C36H33N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0795225
|
1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
Show/Hide
|
C19H16N2O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0403695
|
(E)-3-[4-[(1R,3R)-6-hydroxy-3-methyl-2-(2-methylpropyl)-3,4-dihydro-1H-isoquinolin-1-yl]phenyl]prop-2-enoic acid
Show/Hide
|
C23H27NO3
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0460861
|
4-{(E)-2-[({[2,4-Dichloro-3-(1-methyl-2-phenyl-1H-benzoimidazol-4-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide
Show/Hide
|
C35H31Cl2N5O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0279530
|
2-[8-[[2,6-dichloro-3-[methyl-[2-[[(E)-3-[4-(methylcarbamoyl)phenyl]prop-2-enoyl]amino]acetyl]amino]phenyl]methoxy]-2-methylquinolin-4-yl]oxyacetic acid
Show/Hide
|
C33H30Cl2N4O7
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0720693
|
N-{2-[4-((S)-2-amino-5-(dimethylamino)pentanoyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-2,4-dichloro-3-(2,4-dimethylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C33H44Cl2N6O5S
|
2
|
| 1 |
Kd = 0.7943 nM
|
|
|
| 2 |
Ki = 0.3981 nM
|
|
|
|
CP0682483
|
N-{2-[4-((S)-3-amino-6-(dimethylamino)hexanoyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-2,4-dichloro-3-(2,4-dimethylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C34H46Cl2N6O5S
|
2
|
| 1 |
Kd = 2.512 nM
|
|
|
| 2 |
Ki = 0.631 nM
|
|
|
|
CP0844040
|
N-{2-[4-((S)-3-amino-7-(dimethylamino)heptanoyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-2,4-dichloro-3-(2,4-dimethylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C35H48Cl2N6O5S
|
2
|
| 1 |
Kd = 2.512 nM
|
|
|
| 2 |
Ki = 0.5012 nM
|
|
|
|
CP0844041
|
N-(3-aminopropyl)-4-{2-[2,4-dichloro-3-(2,4-dimethylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionyl}-piperazine-1-carboxamidine
Show/Hide
|
C30H39Cl2N7O4S
|
2
|
| 1 |
Kd = 2.512 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0800203
|
N-{2-[4-((S)-2-amino-6-(dimethylamino)hexanoyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-2,4-dichloro-3-(2,4-dimethylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C34H46Cl2N6O5S
|
2
|
| 1 |
Kd = 3.162 nM
|
|
|
| 2 |
Ki = 0.631 nM
|
|
|
|
CP0671501
|
N-{2-[4-((S)-3-amino-7-guanidinoheptanoyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C33H44Cl2N8O5S
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 1.259 nM
|
|
|
|
CP0728270
|
2,4-dichloro-N-{2-[4-(6-guanidinohexyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C32H43Cl2N7O4S
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
|
CP0881036
|
N-(6-aminohexyl)-4-{2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionyl}-piperazine-1-carboxamidine
Show/Hide
|
C32H43Cl2N7O4S
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0782060
|
N-(3-aminopropyl)-4-{2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionyl}-piperazine-1-carboxamidine
Show/Hide
|
C29H37Cl2N7O4S
|
2
|
| 1 |
Kd = 10.96 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
|
CP0823762
|
N-{2-[4-((S)-2-amino-6-(dimethylamino)hexanoyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C33H44Cl2N6O5S
|
2
|
| 1 |
Kd = 11.22 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0767076
|
N-[(S)-1-(4-{2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionyl}piperazine-1-carbonyl)-5-(dimethylamino)pentyl]acetamide
Show/Hide
|
C35H46Cl2N6O6S
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0943586
|
N-2-[4-(6-aminohexyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl-2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C31H41Cl2N5O4S
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0767077
|
N-{2-[4-((S)-2-amino-5-(dimethylamino)pentanoyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C32H42Cl2N6O5S
|
2
|
| 1 |
Kd = 25.12 nM
|
|
|
| 2 |
Ki = 0.3981 nM
|
|
|
|
CP0794016
|
2,4-dichloro-N-{1,1-dimethyl-2-oxo-2-[4-(2-piperazin-1-ylacetyl)piperazin-1-yl]ethyl}-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C31H38Cl2N6O5S
|
2
|
| 1 |
Kd = 25.12 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0717330
|
4-{2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionyl}piperazine-1-carboxamidine
Show/Hide
|
C26H30Cl2N6O4S
|
2
|
| 1 |
Kd = 39.81 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0767078
|
N-{2-[4-((S)-3-amino-6-(dimethylamino)hexanoyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C33H44Cl2N6O5S
|
2
|
| 1 |
Kd = 39.81 nM
|
|
|
| 2 |
Ki = 0.7943 nM
|
|
|
|
CP0860016
|
N-{2-[4-((S)-3-amino-7-(dimethylamino)heptanoyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C34H46Cl2N6O5S
|
2
|
| 1 |
Kd = 39.81 nM
|
|
|
| 2 |
Ki = 0.631 nM
|
|
|
|
CP0881233
|
2,4-dichloro-N-{2-[4-(2-guanidinoethyl)piperazin-1-yl]-1,1-dimethyl-2-oxoethyl}-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
|
C28H35Cl2N7O4S
|
2
|
| 1 |
Kd = 39.81 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0372893
|
N-[[(3S,13S,16S,19S,22S,25R)-16-(4-aminobutyl)-13-(aminomethyl)-2,12,15,18,21,24-hexaoxo-19-phenyl-1,11,14,17,20,23-hexazapentacyclo[23.8.0.03,11.05,10.027,32]tritriaconta-27,29,31-trien-22-yl]methyl]-2-phenylacetamide
Show/Hide
|
C47H59N9O7
|
1
|
| 1 |
Kd = 200 nM
|
|
|
|
CP0424013
|
N-[(3S,14S,20R,25R)-14-[3-(diaminomethylideneamino)propyl]-2,12,15,19,24-pentaoxo-1,11,13,16,23-pentazapentacyclo[23.8.0.03,11.05,10.027,32]tritriaconta-27,29,31-trien-20-yl]-3-phenylpropanamide
Show/Hide
|
C41H55N9O6
|
1
|
| 1 |
Kd = 200 nM
|
|
|
|
CP0506051
|
3-Aminomethyl-1-(3-amino-propyl)-7-dibenzylamino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one
Show/Hide
|
C33H35N5O
|
1
|
| 1 |
Kd = 4300 nM
|
|
|
|
CP0514496
|
2-[3-[3-[2-(diaminomethylideneamino)ethyl]-7-(dibenzylamino)-2-oxo-5-phenyl-3H-1,4-benzodiazepin-1-yl]propyl]guanidine
Show/Hide
|
C36H41N9O
|
1
|
| 1 |
Kd = 4500 nM
|
|
|
|
CP0392244
|
N-[(1S)-1-(4-butylpyridin-2-yl)-2-cyclohexylethyl]-4-[(diaminomethylideneamino)methyl]benzamide
Show/Hide
|
C26H37N5O
|
1
|
| 1 |
Kd = 5000 nM
|
|
|
|
CP0438958
|
4-Aminomethyl-N-[(S)-1-(4-butyl-pyridin-2-yl)-2-cyclohexyl-ethyl]-benzamide
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Kd = 7400 nM
|
|
|
|
CP0392245
|
1-(3-Aminomethyl-benzyl)-6,6-dibenzyl-1,4,5,6-tetrahydro-indol-7-one
Show/Hide
|
C30H30N2O
|
1
|
| 1 |
Kd = 7600 nM
|
|
|
|
CP0532449
|
2-[3-[3-[(diaminomethylideneamino)methyl]-7-(dibenzylamino)-2-oxo-5-phenyl-3H-1,4-benzodiazepin-1-yl]propyl]guanidine
Show/Hide
|
C35H39N9O
|
1
|
| 1 |
Kd = 12000 nM
|
|
|
|
CP0534571
|
4-Aminomethyl-N-(2,2-dibutyl-benzo[1,3]dioxol-4-yl)-benzamide
Show/Hide
|
C23H30N2O3
|
1
|
| 1 |
Kd = 13000 nM
|
|
|
|
CP0545213
|
4-Aminomethyl-N-(3-amino-propyl)-N-(2,2-dibutyl-benzo[1,3]dioxol-4-yl)-benzamide
Show/Hide
|
C26H37N3O3
|
1
|
| 1 |
Kd = 14000 nM
|
|
|
|
CP0391730
|
2-[[(2R,4R)-1-(naphthalene-2-carbonyl)-4-phenylmethoxypyrrolidin-2-yl]methyl]guanidine
Show/Hide
|
C24H26N4O2
|
1
|
| 1 |
Kd = 15000 nM
|
|
|
|
CP0438947
|
3-(2-Amino-ethyl)-1-(3-amino-propyl)-7-dibenzylamino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one
Show/Hide
|
C34H37N5O
|
1
|
| 1 |
Kd = 15000 nM
|
|
|
|
CP0458730
|
(R)-3-Amino-N-(4-aminomethyl-benzyl)-2-{2-[(2-cyclohexyl-2-phenyl-acetylamino)-methyl]-pyrrol-1-yl}-propionamide
Show/Hide
|
C30H39N5O2
|
1
|
| 1 |
Kd = 17000 nM
|
|
|
|
CP0573185
|
5-Dibutylamino-pentanoic acid [(S)-1-(4-butyl-pyridin-2-yl)-2-cyclohexyl-ethyl]-amide
Show/Hide
|
C30H53N3O
|
1
|
| 1 |
Kd = 23000 nM
|
|
|
|
CP0492216
|
1-[(R)-5-Amino-1-(4-aminomethyl-benzylcarbamoyl)-pentyl]-1H-pyrrole-2-carboxylic acid (1,2-diphenyl-ethyl)-amide
Show/Hide
|
C33H39N5O2
|
1
|
| 1 |
Kd = 28000 nM
|
|
|
|
CP0376103
|
5-Amino-pentanoic acid [(S)-1-(4-butyl-pyridin-2-yl)-2-cyclohexyl-ethyl]-amide
Show/Hide
|
C22H37N3O
|
1
|
| 1 |
Kd = 62000 nM
|
|
|
|
CP0497817
|
((2R,4R)-2-Aminomethyl-4-benzyloxy-pyrrolidin-1-yl)-naphthalen-2-yl-methanone
Show/Hide
|
C23H24N2O2
|
1
|
| 1 |
Kd = 66000 nM
|
|
|
|
CP0874519
|
4-(4-(2,4-Dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)phenylsulfonamido)tetrahydro-2H-pyran-4-carbonyl)-1-methyl-1-(6-(trimethylammonio)hexyl)piperazin-1-ium trifluoroacetate salt
Show/Hide
|
C42H55Cl2F6N5O9S
|
1
|
| 1 |
Ki = 0.03981 nM
|
|
|
|
CP0172614
|
(S)-4-amino-5-(4-(4-(2,4-dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)phenylsulfonamido)tetrahydro-2H-pyran-4-carbonyl)piperazin-1-yl)-N,N,N-trimethyl-5-oxopentan-1-aminium chloride
Show/Hide
|
C36H49Cl2N6O6S+
|
1
|
| 1 |
Ki = 0.05012 nM
|
|
|
|
CP0682478
|
[(S)-4-amino-5-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazin-1-yl)-5-oxo-pentyl]-trimethyl-ammonium
Show/Hide
|
C36H49Cl2N6O5S+
|
1
|
| 1 |
Ki = 0.05012 nM
|
|
|
|
CP0839078
|
[(S)-4-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-thiopyran-4-carbonyl}-piperazin-1-yl)-5-oxo-pentyl]-trimethyl-ammonium
Show/Hide
|
C36H49Cl2N6O5S2+
|
1
|
| 1 |
Ki = 0.05012 nM
|
|
|
|
CP0847134
|
4-(4-(2,4-Dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)phenylsulfonamido)tetrahydro-2H-pyran-4-carbonyl)-1-methyl-1-(5-(trimethylammonio)pentyl)piperazin-1-ium trifluoroacetate salt
Show/Hide
|
C41H53Cl2F6N5O9S
|
1
|
| 1 |
Ki = 0.05012 nM
|
|
|
|
CP0851981
|
2,4-Dichloro-N-{4-[4-((S)-2,5-diamino-pentanoyl)-piperazine-1-carbonyl]-tetrahydro-pyran-4-yl}-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide trifluoroacetate salt
Show/Hide
|
C35H43Cl2F3N6O8S
|
1
|
| 1 |
Ki = 0.05012 nM
|
|
|
|
CP0892092
|
(S)-N-(4-(4-(2-amino-5-(dimethylamino)pentanoyl)piperazine-1-carbonyl)tetrahydro-2H-pyran-4-yl)-2,4-dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)benzenesulfonamide trifluoroacetate salt
Show/Hide
|
C37H47Cl2F3N6O8S
|
1
|
| 1 |
Ki = 0.05012 nM
|
|
|
|
CP0892093
|
{4-[(1-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperidin-4-ylmethyl)-amino]-butyl}-trimethylammonium trifluoroacetate salt
Show/Hide
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C39H52Cl2F3N5O7S
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1
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| 1 |
Ki = 0.05012 nM
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CP0847104
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N-{4-[4-((S)-2-Amino-6-dimethylamino-hexanoyl)-piperazine-1-carbonyl]-tetrahydro-pyran-4-yl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide trifluoroacetate salt
Show/Hide
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C38H49Cl2F3N6O8S
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1
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| 1 |
Ki = 0.0631 nM
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CP0847132
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[6-(4-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperazin-1-yl)-hexyl]-trimethyl-ammonium trifluoroacetate salt
Show/Hide
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C39H52Cl2F3N5O7S
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1
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| 1 |
Ki = 0.0631 nM
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CP0868558
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N-{4-[4-((S)-2-Amino-6-guanidino-hexanoyl)-piperazine-1-carbonyl]-tetrahydro-pyran-4-yl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide trifluoroacetate salt
Show/Hide
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C37H47Cl2F3N8O8S
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1
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| 1 |
Ki = 0.0631 nM
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CP0299612
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(BK) H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH
Show/Hide
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C50H73N15O11
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2
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| 1 |
Ki = 0.065 nM
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| 2 |
Ki = 0.65 nM
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CP0495436
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(3-(Ser-Thi-Gly-Hyp-Pro-Arg-Lys-H)-4-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazepin-5-yl)-acetyl-(Arg-OH)
Show/Hide
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C51H77N17O13S2
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1
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| 1 |
Ki = 0.07 nM
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CP0839077
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[(S)-4-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-1-methyl-piperidine-4-carbonyl}-piperazin-1-yl)-5-oxo-pentyl]-trimethyl-ammonium
Show/Hide
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C37H52Cl2N7O5S+
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1
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| 1 |
Ki = 0.07943 nM
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CP0847133
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4-(4-(2,4-dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)phenylsulfonamido)tetrahydro-2H-pyran-4-carbonyl)-1-methyl-1-(4-(trimethylammonio)butyl)piperazin-1-ium 2,2,2-trifluoroacetate
Show/Hide
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C40H51Cl2F6N5O9S
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1
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| 1 |
Ki = 0.07943 nM
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CP0851983
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[2-(4-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperazin-1-yl)-2-oxo-ethyl]-trimethylammonium trifluoroacetate salt
Show/Hide
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C35H42Cl2F3N5O8S
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1
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| 1 |
Ki = 0.07943 nM
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CP0893994
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[5-(4-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperazin-1-yl)-5-oxo-pentyl]-trimethyl-ammonium trifluoroacetate salt
Show/Hide
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C38H48Cl2F3N5O8S
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1
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| 1 |
Ki = 0.07943 nM
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CP0916503
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N-{4-[4-(5-Amino-pentanoyl)-piperazine-1-carbonyl]-tetrahydro-pyran-4-yl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide trifluoroacetate salt
Show/Hide
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C35H42Cl2F3N5O8S
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1
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| 1 |
Ki = 0.07943 nM
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CP0829543
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[(S)-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazine-1-carbonyl)-5-guanidino-pentyl]-trimethyl-ammonium
Show/Hide
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C38H53Cl2N8O5S+
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1
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| 1 |
Ki = 0.1 nM
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CP0892090
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4-(4-(2,4-Dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)phenylsulfonamido)tetrahydro-2H-pyran-4-carbonyl)-1-methyl-1-(3-(trimethylammonio)propyl)piperazin-1-ium trifluoroacetate salt
Show/Hide
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C39H49Cl2F6N5O9S
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1
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| 1 |
Ki = 0.1 nM
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CP0896456
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(S)-2,4-dichloro-N-(4-(4-(2,6-diaminohexanoyl)piperazine-1-carbonyl)tetrahydro-2H-pyran-4-yl)-3-((2,4-dimethylquinolin-8-yloxy)methyl)benzenesulfonamide trifluoroacetate salt
Show/Hide
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C36H45Cl2F3N6O8S
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1
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| 1 |
Ki = 0.1 nM
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CP0917488
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2,4-Dichloro-N-{4-[4-(5-dimethylamino-pentanoyl)-piperazine-1-carbonyl]-tetrahydro-pyran-4-yl}-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide trifluoroacetate salt
Show/Hide
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C37H46Cl2F3N5O8S
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1
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| 1 |
Ki = 0.1 nM
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CP0779070
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{(S)-4-amino-1-[2-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazin-1-yl)-2-oxo-ethyl]-butyl}-trimethyl-ammonium
Show/Hide
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C37H51Cl2N6O5S+
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1
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| 1 |
Ki = 0.1259 nM
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CP0829542
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[(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium
Show/Hide
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C37H51Cl2N6O5S+
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1
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| 1 |
Ki = 0.1259 nM
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CP0851980
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[4-(4-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperazin-1-yl)-4-oxo-butyl]-trimethyl-ammonium trifluoroacetate salt
Show/Hide
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C37H46Cl2F3N5O8S
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1
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| 1 |
Ki = 0.1259 nM
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CP0853240
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[6-(4-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperazin-1-yl)-6-oxo-hexyl]-trimethyl-ammonium trifluoroacetate salt
Show/Hide
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C39H50Cl2F3N5O8S
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1
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| 1 |
Ki = 0.1259 nM
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CP0919238
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N-{4-[4-((S)-2-Amino-5-guanidino-pentanoyl)-piperazine-1-carbonyl]-tetrahydro-pyran-4-yl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide trifluoroacetate salt
Show/Hide
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C36H45Cl2F3N8O8S
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1
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| 1 |
Ki = 0.1259 nM
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CP0512348
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8-Methyl-3-(2-oxo-propyl)-1-phenethyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
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C19H27N3O2
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1
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| 1 |
Ki = 0.15 nM
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CP0789362
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[(S)-5-(4-{1-acetyl-4-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-piperidine-4-carbonyl}-piperazin-1-yl)-4-amino-5-oxo-pentyl]-trimethyl-ammonium
Show/Hide
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C38H52Cl2N7O6S+
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1
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| 1 |
Ki = 0.1585 nM
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CP0853852
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{3-[(1-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperidin-4-ylmethyl)-amino]-propyl}-trimethylammonium trifluoroacetate salt
Show/Hide
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C38H50Cl2F3N5O7S
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1
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| 1 |
Ki = 0.1585 nM
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CP0702267
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[5-(4-(1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl]-piperazin-1-yl)-4(S)-trimethylammonio-5-oxo-pentyl]trimethyl-ammonium
Show/Hide
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C39H56Cl2N6O5S+2
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1
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| 1 |
Ki = 0.1995 nM
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CP0702268
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N-[1-[4-(2-(S)-trimethylammonium-6-trimethylammoniumhexanoyl)-piperazin-1-yl]-cyclopentyl]-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide
Show/Hide
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C40H58Cl2N6O5S+2
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1
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| 1 |
Ki = 0.1995 nM
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CP0711141
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[(S)-4-amino-6-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazin-1-yl)-6-oxo-hexyl]-trimethyl-ammonium
Show/Hide
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C37H51Cl2N6O5S+
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1
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| 1 |
Ki = 0.1995 nM
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CP0800202
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N-{1-[4-((S)-2,6-bis-dimethylamino-hexanoyl)-piperazine-1-carbonyl]-cyclopentyl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide
Show/Hide
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C38H52Cl2N6O5S
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1
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| 1 |
Ki = 0.1995 nM
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CP0916501
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{2-[(1-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperidin-4-ylmethyl)-amino]-ethyl}-trimethylammonium trifluoroacetate salt
Show/Hide
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C37H48Cl2F3N5O7S
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1
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| 1 |
Ki = 0.1995 nM
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CP0917487
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7-(4-(4-(2,4-dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)phenylsulfonamido)tetrahydro-2H-pyran-4-carbonyl)piperazin-1-yl)-N,N,N-trimethyl-7-oxoheptan-1-aminium trifluoroacetate salt
Show/Hide
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C40H52Cl2F3N5O8S
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1
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| 1 |
Ki = 0.1995 nM
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CP0682476
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[(S)-4-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazine-1-carbonyl)-butyl]-trimethyl-ammonium
Show/Hide
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C36H49Cl2N6O5S+
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1
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| 1 |
Ki = 0.2512 nM
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CP0829540
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[5-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazin-1-yl)-5-oxo-pentyl]-trimethyl-ammonium
Show/Hide
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C36H48Cl2N5O5S+
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1
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| 1 |
Ki = 0.2512 nM
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CP0847105
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4-(4-(2,4-Dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)phenylsulfonamido)tetrahydro-2H-pyran-4-carbonyl)-1-methyl-1-(2-(trimethylammonio)ethyl)piperazin-1-ium trifluoroacetate salt
Show/Hide
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C38H47Cl2F6N5O9S
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1
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| 1 |
Ki = 0.2512 nM
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CP0853853
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9-(4-(2,4-Dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)phenylsulfonamido)tetrahydro-2H-pyran-4-carbonyl)-3,3-dimethyl-9-aza-3,6-diazoniaspiro[5.5]undecane trifluoroacetate salt
Show/Hide
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C38H45Cl2F6N5O9S
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1
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| 1 |
Ki = 0.2512 nM
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CP0867622
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(S)-5-Amino-6-(4-(4-(2,4-dichloro-3-((2,4-dimethylquinolin-8-yloxy)methyl)phenylsulfonamido)tetrahydro-2Hpyran-4-carbonyl)piperazin-1-yl)-N,N,N-trimethyl-6-oxohexan-1-aminium trifluoroacetate salt
Show/Hide
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C39H51Cl2F3N6O8S
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1
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| 1 |
Ki = 0.2512 nM
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CP0711142
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2,4-dichloro-N-{1-[4-((S)-2,6-diamino-hexanoyl)-piperazine-1-carbonyl]-cyclopentyl}-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide
Show/Hide
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C34H44Cl2N6O5S
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1
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| 1 |
Ki = 0.3162 nM
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CP0829541
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[(S)-3-amino-4-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazin-1-yl)-4-oxo-butyl]-trimethyl-ammonium
Show/Hide
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C35H47Cl2N6O5S+
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1
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| 1 |
Ki = 0.3162 nM
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CP0894501
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[3-(4-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperazin-1-yl)-propyl]-trimethyl-ammonium trifluoroacetate salt
Show/Hide
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C36H46Cl2F3N5O7S
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1
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| 1 |
Ki = 0.3162 nM
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CP0711137
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{3-[(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazine-1-carboximidoyl)-amino]-propyl}-trimethyl-ammonium
Show/Hide
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C35H48Cl2N7O4S+
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1
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| 1 |
Ki = 0.3981 nM
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CP0711139
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[2-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazin-1-yl)-2-oxo-ethyl]-trimethyl-ammonium
Show/Hide
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C33H42Cl2N5O5S+
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1
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| 1 |
Ki = 0.3981 nM
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CP0789361
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LF16-0687
Show/Hide
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C34H36Cl2N6O5S
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2
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| 1 |
Ki = 0.3981 nM
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| 2 |
Ki = 0.7943 nM
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CP0860944
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[4-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazin-1-yl)-4-oxo-butyl]-trimethyl-ammonium
Show/Hide
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C35H46Cl2N5O5S+
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1
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| 1 |
Ki = 0.3981 nM
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CP0847138
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3-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-3-aza-6-azonia-spiro[5.5]undecane trifluoroacetate salt
Show/Hide
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C35H41Cl2F3N4O7S
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1
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| 1 |
Ki = 0.3981 nM
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CP0894500
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(1-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperidin-4-ylmethyl)-trimethyl-ammonium trifluoroacetate salt
Show/Hide
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C35H43Cl2F3N4O7S
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1
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| 1 |
Ki = 0.3981 nM
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CP0789363
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[(S)-4-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-piperidine-4-carbonyl}-piperazin-1-yl)-5-oxo-pentyl]-trimethyl-ammonium
Show/Hide
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C36H50Cl2N7O5S+
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1
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| 1 |
Ki = 0.5012 nM
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CP0800199
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[6-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazin-1-yl)-6-oxo-hexyl]-trimethyl-ammonium
Show/Hide
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C37H50Cl2N5O5S+
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1
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| 1 |
Ki = 0.5012 nM
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CP0847137
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[3-(1-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperidin-4-yl)-propyl]-trimethyl-ammonium trilfuoroacetate salt
Show/Hide
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C37H47Cl2F3N4O7S
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1
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| 1 |
Ki = 0.5012 nM
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CP0450266
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1-Cyclohexyl-8-methyl-3-(2-oxo-propyl)-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
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C17H29N3O2
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1
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| 1 |
Ki = 0.57 nM
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CP0682481
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2,4-dichloro-N-{1-[4-((S)-3,6-diamino-hexanoyl)-piperazine-1-carbonyl]-cyclopentyl}-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide
Show/Hide
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C34H44Cl2N6O5S
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1
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| 1 |
Ki = 0.631 nM
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CP0789364
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4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-N-(3-dimethylamino-propyl)-piperazine-1-carboxamidine
Show/Hide
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C34H45Cl2N7O4S
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1
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| 1 |
Ki = 0.631 nM
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CP0800201
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[(S)-5-amino-6-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazin-1-yl)-6-oxo-hexyl]-trimethyl-ammonium
Show/Hide
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C37H51Cl2N6O5S+
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1
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| 1 |
Ki = 0.631 nM
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CP0829544
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N-{1-[4-((S)-3-amino-6-dimethylamino-hexanoyl)-piperazine-1-carbonyl]-cyclopentyl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide
Show/Hide
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C36H48Cl2N6O5S
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1
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| 1 |
Ki = 0.631 nM
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CP0829545
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N-{2-[4-((S)-2-amino-6-guanidino-hexanoyl)-piperazin-1-yl]-1,1-dimethyl-2-oxo-ethyl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide
Show/Hide
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C33H44Cl2N8O5S
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1
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| 1 |
Ki = 0.631 nM
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CP0847135
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8-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-8-aza-5-azonia-spiro[4.5]decane trifluoroacetate salt
Show/Hide
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C34H39Cl2F3N4O7S
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1
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| 1 |
Ki = 0.631 nM
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CP0859150
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[4-(1-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperidin-4-yl)-butyl]-trimethyl-ammonium trilfuoroacetate salt
Show/Hide
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C38H49Cl2F3N4O7S
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1
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| 1 |
Ki = 0.631 nM
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CP0453331
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(2S)-2-[[2-[(3S)-3-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-thiophen-2-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl]acetyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Show/Hide
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C51H77N19O13S2
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1
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| 1 |
Ki = 0.7 nM
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CP0441003
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(JMV 1116) H-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-BT-Arg-OH
Show/Hide
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C51H77N19O13S2
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1
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| 1 |
Ki = 0.7 nM
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CP0682479
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N-{1-[4-((S)-3-amino-6-guanidino-hexanoyl)-piperazine-1-carbonyl]-cyclopentyl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide
Show/Hide
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C35H46Cl2N8O5S
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1
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| 1 |
Ki = 0.7943 nM
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CP0847136
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[2-(1-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperidin-4-yl)-ethyl]-trimethyl-ammonium trilfuoroacetate salt
Show/Hide
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C36H45Cl2F3N4O7S
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1
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| 1 |
Ki = 0.7943 nM
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CP0893995
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[2-(4-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-piperazin-1-yl)-ethyl]-trimethyl-ammonium trifluoroacetate salt
Show/Hide
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C35H44Cl2F3N5O7S
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1
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| 1 |
Ki = 0.7943 nM
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CP0789365
|
N-{1-[4-((S)-2-amino-6-guanidino-hexanoyl)-piperazine-1-carbonyl]-cyclopentyl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide
Show/Hide
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C35H46Cl2N8O5S
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1
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| 1 |
Ki = 1 nM
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CP0847106
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3-{4-[2,4-Dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-tetrahydro-pyran-4-carbonyl}-9-methyl-3,9-diaza-6-azonia-spiro[5.5]undecane trifluoroacetate salt
Show/Hide
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C35H42Cl2F3N5O7S
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1
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| 1 |
Ki = 1 nM
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CP0800200
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2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-N-{1-[4-(6-guanidino-hexanoyl)-piperazine-1-carbonyl]-cyclopentyl}-benzenesulfonamide
Show/Hide
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C35H45Cl2N7O5S
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1
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| 1 |
Ki = 1.259 nM
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CP0871079
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N-{1-[4-((S)-2-amino-6-dimethylamino-hexanoyl)-piperazine-1-carbonyl]-cyclopentyl}-2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonamide
Show/Hide
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C36H48Cl2N6O5S
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1
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| 1 |
Ki = 1.585 nM
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CP0503621
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(3-(Ser-Thi-Gly-Hyp-Pro-Arg-D-Arg-H)-4-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazepin-5-yl)-acetyl-(Arg-OH)
Show/Hide
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C51H77N19O14S
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1
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| 1 |
Ki = 2.5 nM
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CP0540254
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(3-(Ser-Thi-Gly-Hyp-Pro-Arg-D-Arg-H),-8-methyl-4-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazepin-5-yl)-acetyl-(Arg-OH)
Show/Hide
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C52H79N19O13S2
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1
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| 1 |
Ki = 6 nM
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CP0402469
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8-Methyl-3-(2-oxo-propyl)-1-p-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
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C18H25N3O2
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1
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| 1 |
Ki = 6.3 nM
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CP0502232
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1-Cyclohexylmethyl-8-methyl-3-(2-oxo-propyl)-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
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C18H31N3O2
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1
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| 1 |
Ki = 6.8 nM
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CP0401193
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8-Methyl-3-(2-oxo-propyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
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C17H23N3O2
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1
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| 1 |
Ki = 7.7 nM
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CP0720552
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N-[3-(4-carbamimidoylphenylamino)propyl]-2-[2,4-dichloro-3-(2,4-dimethylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionamide
Show/Hide
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C32H36Cl2N6O4S
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1
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| 1 |
Ki = 7.943 nM
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CP0498021
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(2R)-2-[[2-[3-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl]acetyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Show/Hide
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C47H67N15O12S
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1
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| 1 |
Ki = 13 nM
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CP0382358
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(3-(Ser-Thi-Gly-Hyp-Pro-Arg-D-Arg-H)-3,5-dibenzyl-2,4-dioxo-pyrrolidin-1-yl)-acetyl-(Arg-OH)
Show/Hide
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C60H85N19O14S
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1
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| 1 |
Ki = 14 nM
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CP0885436
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LABRADIMIL
Show/Hide
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C49H75N15O12S
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1
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| 1 |
Ki = 19 nM
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CP0868775
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(RMP-7) H-Arg-Pro-Hyp-Gly-Thi-Ser-Pro-4-Me-Tyr(CH2NH)-Arg-OH
Show/Hide
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C49H75N15O11S
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1
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| 1 |
Ki = 19 nM
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CP0697684
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-(2-guanidinoethyl)-2-methylpropionamide
Show/Hide
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C24H28Cl2N6O4S
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1
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| 1 |
Ki = 19.95 nM
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CP0889523
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N-[3-(4-carbamimidoylphenylamino)propyl]-2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionamide
Show/Hide
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C31H34Cl2N6O4S
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1
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| 1 |
Ki = 19.95 nM
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CP0714600
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2,4-dichloro-N-(2-[1,4]diazepan-1-yl-1,1-dimethyl-2-oxoethyl)-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
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C26H30Cl2N4O4S
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1
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| 1 |
Ki = 25.12 nM
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CP0741508
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2,4-dichloro-N-[1,1-dimethyl-2-(4-methylpiperazin-1-yl)-2-oxoethyl]-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
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C25H28Cl2N4O4S
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1
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| 1 |
Ki = 25.12 nM
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CP0938800
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N-(3-aminopropyl)-2-[2,4-dichloro-3-(2,4-dimethylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionamide
Show/Hide
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C25H30Cl2N4O4S
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1
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| 1 |
Ki = 25.12 nM
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CP0509495
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8-Methyl-3-(2-oxo-propyl)-1-propyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
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C14H25N3O2
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1
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| 1 |
Ki = 27 nM
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CP0728064
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-(3-guanidinopropyl)-2-methylpropionamide
Show/Hide
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C25H30Cl2N6O4S
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1
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| 1 |
Ki = 39.81 nM
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CP0805582
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-{3-[(pyridin-2-ylmethyl)amino]-propyl}propionamide
Show/Hide
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C30H33Cl2N5O4S
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1
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| 1 |
Ki = 39.81 nM
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CP0734160
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2,4-dichloro-N-(2-guanidino-1,1-dimethyl-2-oxoethyl)-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
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C22H23Cl2N5O4S
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1
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| 1 |
Ki = 63.1 nM
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CP0697683
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-[3-(4-methanesulfonylbenzylamino)propyl]-2-methylpropionamide
Show/Hide
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C32H36Cl2N4O6S2
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1
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| 1 |
Ki = 79.43 nM
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CP0741203
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-piperidin-4-ylpropionamide
Show/Hide
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C26H30Cl2N4O4S
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1
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| 1 |
Ki = 79.43 nM
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CP0855223
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-[3-(4-hydroxybenzylamino)propyl]-2-methylpropionamide
Show/Hide
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C31H34Cl2N4O5S
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1
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| 1 |
Ki = 79.43 nM
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CP0714601
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N-(2-azepan-1-yl-1,1-dimethyl-2-oxoethyl)-2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonamide
Show/Hide
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C27H32Cl2N4O4S
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1
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| 1 |
Ki = 100 nM
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CP0741205
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N-(2-aminoethyl)-2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionamide
Show/Hide
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C23H26Cl2N4O4S
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1
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| 1 |
Ki = 100 nM
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CP0655985
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4-[(3-{2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)-benzenesulfonylamino]-2-methylpropionylamino}propylamino)-methyl]benzamide
Show/Hide
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C32H35Cl2N5O5S
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1
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| 1 |
Ki = 125.89 nM
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CP0380892
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(2R)-2-[[(2R,11R)-11-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-thiophen-2-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-12-oxo-1-azatricyclo[6.4.1.04,13]trideca-4,6,8(13)-triene-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Show/Hide
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C53H79N19O13S
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1
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| 1 |
Ki = 140 nM
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CP0655988
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-piperidin-4-ylmethyl-ropionamide
Show/Hide
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C27H32Cl2N4O4S
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1
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| 1 |
Ki = 158.49 nM
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CP0711276
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-[3-(4-(dimethylamino)benzylamino)propyl]-2-methylpropionamide
Show/Hide
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C33H39Cl2N5O4S
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1
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| 1 |
Ki = 158.49 nM
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CP0794022
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-{3-[(1H-imidazol-4-ylmethyl)amino]propyl}-2-methylpropionamide
Show/Hide
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C28H32Cl2N6O4S
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1
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| 1 |
Ki = 158.49 nM
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CP0826746
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N-(3-aminopropyl)-2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionamide
Show/Hide
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C24H28Cl2N4O4S
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1
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| 1 |
Ki = 158.49 nM
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CP0467544
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(2R)-2-[[(2R,11S)-11-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-thiophen-2-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-12-oxo-1-azatricyclo[6.4.1.04,13]trideca-4,6,8(13)-triene-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Show/Hide
|
C53H79N19O13S
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1
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| 1 |
Ki = 160 nM
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CP0429351
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(2S)-2-[[2-[(3R)-3-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-thiophen-2-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl]acetyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Show/Hide
|
C51H77N19O13S2
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1
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| 1 |
Ki = 162 nM
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CP0711277
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-[3-(4-methoxybenzylamino)propyl]-2-methylpropionamide
Show/Hide
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C32H36Cl2N4O5S
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1
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| 1 |
Ki = 199.53 nM
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CP0717344
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N-(3-benzylaminopropyl)-2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionamide
Show/Hide
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C31H34Cl2N4O4S
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1
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| 1 |
Ki = 199.53 nM
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CP0741204
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-(3-(dimethylamino)propyl)-2-methylpropionamide
Show/Hide
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C26H32Cl2N4O4S
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1
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| 1 |
Ki = 199.53 nM
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CP0794023
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-[3-(4-methylbenzylamino)propyl]-propionamide
Show/Hide
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C32H36Cl2N4O4S
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1
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| 1 |
Ki = 199.53 nM
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CP0826744
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N-(4-aminobutyl)-2-[2,4-dichloro-3-(2,4-dimethylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionamide
Show/Hide
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C25H30Cl2N4O4S
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1
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| 1 |
Ki = 199.53 nM
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|
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CP0714602
|
2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-[3-(4-methylpiperazin-1-yl)propyl]-propionamide
Show/Hide
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C29H37Cl2N5O4S
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1
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| 1 |
Ki = 251.19 nM
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CP0708285
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-{3-[(furan-3-ylmethyl)amino]propyl}-2-methylpropionamide
Show/Hide
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C29H32Cl2N4O5S
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1
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| 1 |
Ki = 316.23 nM
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CP0711280
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-(2-piperidin-1-yl-ethyl)propionamide
Show/Hide
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C28H34Cl2N4O4S
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1
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| 1 |
Ki = 316.23 nM
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CP0711278
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-[3-(4-fluorobenzylamino)propyl]-2-methylpropionamide
Show/Hide
|
C31H33Cl2FN4O4S
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1
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| 1 |
Ki = 398.11 nM
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CP0839545
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-(3-methoxypropyl)-2-methylpropionamide
Show/Hide
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C25H29Cl2N3O5S
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1
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| 1 |
Ki = 398.11 nM
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CP0405160
|
(3-(Ser-Thi-Gly-Hyp-Pro-Arg-D-Arg-H)-2-oxo-azepan-1-yl)-acetyl(Arg-OH)
Show/Hide
|
C48H79N19O13S
|
1
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| 1 |
Ki = 520 nM
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CP0655987
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-(3-morpholin-4-yl-propyl)propionamide
Show/Hide
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C28H34Cl2N4O5S
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1
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| 1 |
Ki = 630.96 nM
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CP0460852
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(3-(Ser-Thi-Gly-Hyp-Pro-Arg-D-Arg-H)-2-oxo-azepan-1-yl)-acetyl(Arg-OH)
Show/Hide
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C48H79N19O13S
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1
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| 1 |
Ki = 770 nM
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CP0655986
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2N-[3-(4-chlorobenzylamino)propyl]-2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methylpropionamide
Show/Hide
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C31H33Cl3N4O4S
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1
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| 1 |
Ki = 794.33 nM
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CP0496721
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(3-(Ser-Thi-Gly-Hyp-Pro-Arg-D-Arg-H),-2-oxo-pyrrolidin-1-yl)-acetyl-(Arg-OH)
Show/Hide
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C46H75N19O13S
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1
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| 1 |
Ki = 1030 nM
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CP0449428
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2-(3-(Ser-Thi-Gly-Hyp-Pro-Arg-D-Arg-H),-2-oxo-pyrrolidin-1-yl)-3-phenyl-propionyl(Arg-OH)
Show/Hide
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C53H81N19O13S
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1
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| 1 |
Ki = 2070 nM
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CP0711279
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2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-(2-morpholin-4-ylethyl)propionamide
Show/Hide
|
C27H32Cl2N4O5S
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1
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| 1 |
Ki = 2511.89 nM
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CP0403148
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(3-(Ser-Thi-Gly-Hyp-Pro-Arg-D-Arg-H),-2-oxo-pyrrolidin-1-yl)-acetyl-(Arg-OH)
Show/Hide
|
C46H75N19O13S
|
1
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| 1 |
Ki = 4900 nM
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CP0684116
|
2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-phenylpropionamide
Show/Hide
|
C27H25Cl2N3O4S
|
1
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| 1 |
Ki = 7943.28 nM
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CP0949151
|
2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-N-(2-methoxyethyl)-2-methylpropionamide
Show/Hide
|
C24H27Cl2N3O5S
|
1
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| 1 |
Ki = 7943.28 nM
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CP0484248
|
4'-{(R)-1-[3-(2-cyano-acetylamino)-4-methyl-pyridin-2-ylamino]-ethyl}-5-methyl-biphenyl-2-carboxylic acid methyl ester
Show/Hide
|
C26H26N4O3
|
1
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| 1 |
Ki > 10000 nM
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CP0445479
|
(3-(Ser-Thi-Gly-Hyp-Pro-Arg-D-Arg-H)-2-oxo-piperdine-1-yl)-acetyl(Arg-OH)
Show/Hide
|
C47H77N19O13S
|
1
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| 1 |
Ki = 18600 nM
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CP0794024
|
2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-(3-phenylpropyl)propionamide
Show/Hide
|
C30H31Cl2N3O4S
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1
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| 1 |
Ki < 10000 nM
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CP0794025
|
N-benzyl-2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)-benzenesulfonylamino]-2-methylpropionamide
Show/Hide
|
C28H27Cl2N3O4S
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1
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| 1 |
Ki < 10000 nM
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CP0826025
|
2-[2,4-dichloro-3-(2-methylquinolin-8-yloxymethyl)benzenesulfonylamino]-2-methyl-N-phenethylpropionamide
Show/Hide
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C29H29Cl2N3O4S
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1
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| 1 |
Ki < 10000 nM
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