Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

(BK) H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH

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PubChem ID

CID: 439201

SID: 15090019

Canonical SMILES	N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(O)=O Show/Hide
Compound Formula	C50H73N15O11

Compound Structure

Protein Name

Protein Info

B2 bradykinin receptor

Protein Classification

Membrane receptor

Family A G protein-coupled receptor

Peptide receptor (family A GPCR)

Short peptide receptor (family A GPCR)

Bradykinin receptor

Uniprot ID

P30411

Gene Name

BDKRB2

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000064	Chem-1 Cell Line Info	Rattus norvegicus (Rat)	2
1	IC50 = 1.8 nM	TI LI LO TS
2	Ki = 1.1 nM	TI LI LO TS
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	2
1	Ki = 0.065 nM	TI LI LO TS
2	Ki = 0.65 nM	TI LI LO TS

Biochemical Assays

1	Ki = 0.11 nM