Brief Information of the Compound and Protein
Compound Name
(E)-N-({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[6-((E)-2-pyridin-4-yl-vinyl)-pyridin-3-yl]-acrylamide
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PubChem ID
CID: 10371910
SID: 15385480
Canonical SMILES
CN(C(=O)CNC(=O)\C=C\c1ccc(\C=C\c2ccncc2)nc1)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl
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Compound Formula C35H29Cl2N5O3
Compound Structure
Protein Name
B2 bradykinin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Bradykinin receptor
Uniprot ID
P30411
Gene Name
BDKRB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.51 nM
   TI
   LI
   LO
   TS