Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01366 , D(3) dopamine receptor
Gene Name DRD3
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P19020
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT01366
 
Compound ID Compound Name Compound Formula
CP0380255
2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-[2-[4-(7-chloro-1H-indol-6-yl)piperazin-1-yl]ethyl]amino]acetonitrile;2,2,2-trifluoroacetic acid
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C25H29ClF3N7O2S
 1
1
Ki = 0.145 nM
   TI
   LI
   LO
   TS
CP0249245
4-[5-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]pentyl]benzene-1,2-diol
   Show/Hide
C24H33NO3
 1
1
Ki = 0.493 nM
   TI
   LI
   LO
   TS
CP0463479
4-[6-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]hexyl]-2-methoxyphenol
   Show/Hide
C23H35N3O2S
 1
1
Ki = 0.675 nM
   TI
   LI
   LO
   TS
CP0901812
(S)-(-)-6-((2-(4-(3'-Hydroxybiphenyl-4-yl)piperazin-1-yl)ethyl)-(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C31H39N3O2
 1
1
Ki = 0.77 nM
   TI
   LI
   LO
   TS
CP0463477
2-[5-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]pentyl]benzene-1,4-diol
   Show/Hide
C21H31N3O2S
 1
1
Ki = 0.78 nM
   TI
   LI
   LO
   TS
CP0376400
(-)-(S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C25H35N3O
 2
1
Ki = 0.825 nM
   TI
   LI
   LO
   TS
2
Ki = 0.83 nM
   TI
   LI
   LO
   TS
CP0413891
(6S)-6-N-[2-[4-(5-chloro-1H-indol-4-yl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
   Show/Hide
C26H34ClF3N6O2S
 1
1
Ki = 0.87 nM
   TI
   LI
   LO
   TS
CP0397619
(6S)-6-[9-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]nonyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C35H54N2O2
 1
1
Ki = 0.9 nM
   TI
   LI
   LO
   TS
CP0422698
(-)-N6-(2-(4-(Biphenyl-4-yl)piperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
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C28H37N5S
 1
1
Ki = 0.92 nM
   TI
   LI
   LO
   TS
CP0402710
(S)-N*6*-[2-(4-Biphenyl-4-yl-piperazin-1-yl)-ethyl]-N*6*-propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine
   Show/Hide
C28H37N5S
 2
1
Ki = 0.92 nM
   TI
   LI
   LO
   TS
2
Ki = 0.925 nM
   TI
   LI
   LO
   TS
CP0530227
2-[5-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]pentyl]benzene-1,4-diol
   Show/Hide
C21H31N3O2S
 1
1
Ki = 1.01 nM
   TI
   LI
   LO
   TS
CP0381603
[4-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]-(1H-indol-3-yl)methanone
   Show/Hide
C25H34N6OS
 1
1
Ki = 1.09 nM
   TI
   LI
   LO
   TS
CP0493577
(6S)-6-[7-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]heptyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C33H50N2O2
 1
1
Ki = 1.1 nM
   TI
   LI
   LO
   TS
CP0499443
(6S)-6-[2-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]ethyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C28H40N2O2
 1
1
Ki = 1.1 nM
   TI
   LI
   LO
   TS
CP0451725
(6S)-6-N-[2-[4-(7-chloro-1H-indol-6-yl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
   Show/Hide
C26H34ClF3N6O2S
 1
1
Ki = 1.15 nM
   TI
   LI
   LO
   TS
CP0869968
rac-4'-(4-(2-((2-Amino-4,5,6,7-tetrahydrobenzo[d]-thiazol-6-yl)(propyl)amino)ethyl)piperazin-1-yl)-[1,1'-biphenyl]-4-ol
   Show/Hide
C28H37N5OS
 1
1
Ki = 1.17 nM
   TI
   LI
   LO
   TS
CP0911721
rac-4'-(4-(2-((2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)-(propyl)amino)-ethyl)piperazin-1-yl)-[1,1'-biphenyl]-3-ol
   Show/Hide
C28H37N5OS
 1
1
Ki = 1.2 nM
   TI
   LI
   LO
   TS
CP0103545
(-)-5-hydroxy-2-(dipropylamino)tetralin
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C16H25NO
 2
1
Ki = 1.36 nM
   TI
   LI
   LO
   TS
2
Ki = 2.07 nM
   TI
   LI
   LO
   TS
CP0413983
(2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
   Show/Hide
C16H25NO
 3
1
Ki = 1.36 nM
   TI
   LI
   LO
   TS
2
Ki = 1.4 nM
   TI
   LI
   LO
   TS
3
Ki = 2.07 nM
   TI
   LI
   LO
   TS
CP0445313
[4-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]-(1H-indol-5-yl)methanone
   Show/Hide
C25H34N6OS
 1
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS
CP0869969
rac-N6-(2-(4-(4'-Methoxybiphenyl-4-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
   Show/Hide
C29H39N5OS
 1
1
Ki = 1.41 nM
   TI
   LI
   LO
   TS
CP0249244
4-[5-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]pentyl]benzene-1,2-diol
   Show/Hide
C21H31N3O2S
 1
1
Ki = 1.42 nM
   TI
   LI
   LO
   TS
CP0428450
(-)-6-(propyl(2-(4-(4-(pyridin-4-yl)-phenyl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C30H38N4O
 1
1
Ki = 1.53 nM
   TI
   LI
   LO
   TS
CP0378423
7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C25H35N3O
 1
1
Ki = 1.56 nM
   TI
   LI
   LO
   TS
CP0482680
4-[5-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]pentyl]-2-methoxyphenol
   Show/Hide
C22H33N3O2S
 1
1
Ki = 1.57 nM
   TI
   LI
   LO
   TS
CP0373906
(4-{2-[(7-hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-5-yl)-methanone
   Show/Hide
C28H36N4O2
 1
1
Ki = 1.67 nM
   TI
   LI
   LO
   TS
CP0431182
Benzo[b]thiophen-2-yl-(4-{2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-methanone
   Show/Hide
C28H35N3O2S
 1
1
Ki = 1.69 nM
   TI
   LI
   LO
   TS
CP0381126
3-[4-[4-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]phenyl]phenol
   Show/Hide
C28H37N5OS
 1
1
Ki = 1.73 nM
   TI
   LI
   LO
   TS
CP0514098
[4-[4-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]butyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
   Show/Hide
C27H38N6OS
 1
1
Ki = 1.74 nM
   TI
   LI
   LO
   TS
CP0439502
(+)-(R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C25H35N3O
 1
1
Ki = 1.77 nM
   TI
   LI
   LO
   TS
CP0452782
(6S)-6-[10-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]decyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C36H56N2O2
 1
1
Ki = 1.8 nM
   TI
   LI
   LO
   TS
CP0869967
rac-4'-(4-(2-((2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)-(propyl)amino)ethyl)-piperazin-1-yl)biphenyl-2-ol
   Show/Hide
C28H37N5OS
 1
1
Ki = 1.8 nM
   TI
   LI
   LO
   TS
CP0413985
[4-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
   Show/Hide
C25H34N6OS
 1
1
Ki = 1.84 nM
   TI
   LI
   LO
   TS
CP0375066
[4-[2-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
   Show/Hide
C25H34N6OS
 2
1
Ki = 1.84 nM
   TI
   LI
   LO
   TS
2
Ki = 4.59 nM
   TI
   LI
   LO
   TS
CP0445265
6-N-[2-[4-(1H-indol-5-yl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
   Show/Hide
C24H34N6S
 1
1
Ki = 1.92 nM
   TI
   LI
   LO
   TS
CP0497190
7-(propyl(2-(4-(pyridin-2-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C24H34N4O
 1
1
Ki = 1.96 nM
   TI
   LI
   LO
   TS
CP0510543
7-((2-(4-(1H-indol-5-yl)piperazin-1-yl)ethyl)(propyl)-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
   Show/Hide
C27H36N4O
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0918373
rac-N6-(2-(4-(3'-Methoxybiphenyl-4-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
   Show/Hide
C29H39N5OS
 1
1
Ki = 2.11 nM
   TI
   LI
   LO
   TS
CP0499931
(6S)-6-N-[2-[4-(1H-indol-5-yl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
   Show/Hide
C24H34N6S
 1
1
Ki = 2.19 nM
   TI
   LI
   LO
   TS
CP0482388
(6S)-6-[6-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]hexyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C32H48N2O2
 1
1
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CP0906080
(+/-)-4-Methoxy-N-(7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-yl)benzenesulfonamide
   Show/Hide
C32H42N4O3S
 1
1
Ki = 2.22 nM
   TI
   LI
   LO
   TS
CP0411950
(-)-(S)-N6-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine
   Show/Hide
C25H34N6S
 1
1
Ki = 2.23 nM
   TI
   LI
   LO
   TS
CP0388069
(S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-5-yl)-methanone
   Show/Hide
C28H36N4O2
 1
1
Ki = 2.27 nM
   TI
   LI
   LO
   TS
CP0912856
(+)-(R)-4-Methoxy-N-(7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-yl)benzenesulfonamide
   Show/Hide
C32H42N4O3S
 1
1
Ki = 2.32 nM
   TI
   LI
   LO
   TS
CP0469127
(6S)-6-N-[2-[4-[4-(3-methoxyphenyl)phenyl]piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
   Show/Hide
C29H39N5OS
 1
1
Ki = 2.33 nM
   TI
   LI
   LO
   TS
CP0162854
(+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C16H25NO
 2
1
Ki = 2.35 nM
   TI
   LI
   LO
   TS
2
Ki = 6.19 nM
   TI
   LI
   LO
   TS
CP0957297
rac-4-(4-(2-((2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)-(propyl)amino)ethyl)-piperazin-1-yl)-[1,1'-biphenyl]-3-ol
   Show/Hide
C28H37N5OS
 1
1
Ki = 2.35 nM
   TI
   LI
   LO
   TS
CP0374106
(-)-6-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C31H39N3O
 1
1
Ki = 2.36 nM
   TI
   LI
   LO
   TS
CP0460586
4-[5-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]pentyl]benzene-1,2-diol
   Show/Hide
C21H31N3O2S
 1
1
Ki = 2.59 nM
   TI
   LI
   LO
   TS
CP0446347
[4-[3-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]propyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
   Show/Hide
C26H36N6OS
 1
1
Ki = 2.78 nM
   TI
   LI
   LO
   TS
CP0510542
(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indazol-3-yl)-methanone
   Show/Hide
C27H35N5O2
 1
1
Ki = 2.83 nM
   TI
   LI
   LO
   TS
CP0477528
7-(propyl(2-(4-(pyridin-3-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C24H34N4O
 1
1
Ki = 2.89 nM
   TI
   LI
   LO
   TS
CP0406226
7-[propyl-[2-[4-(4-pyridin-3-ylphenyl)piperazin-1-yl]ethyl]amino]-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C30H38N4O
 1
1
Ki = 3.01 nM
   TI
   LI
   LO
   TS
CP0514068
6-[2-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]ethyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C28H38N4O
 1
1
Ki = 3.2 nM
   TI
   LI
   LO
   TS
CP0957868
rac-N6-(2-(4-(2'-Methoxybiphenyl-4-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
   Show/Hide
C29H39N5OS
 1
1
Ki = 3.57 nM
   TI
   LI
   LO
   TS
CP0499442
(6S)-6-[5-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]pentyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C31H46N2O2
 1
1
Ki = 3.6 nM
   TI
   LI
   LO
   TS
CP0407603
(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-3-yl)-methanone
   Show/Hide
C28H36N4O2
 1
1
Ki = 3.62 nM
   TI
   LI
   LO
   TS
CP0564705
4-[5-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]pentyl]-2-methoxyphenol
   Show/Hide
C22H33N3O2S
 1
1
Ki = 3.62 nM
   TI
   LI
   LO
   TS
CP0967238
rac-N6-(2-(4-([1,1'-Biphenyl]-4-yl)piperazin-1-yl)-ethyl)-N6-propyl-5,6,7,8-tetrahydroquinazoline-2,6-diamine
   Show/Hide
C29H38N6
 1
1
Ki = 3.65 nM
   TI
   LI
   LO
   TS
CP0463041
(6S)-6-N-[2-[4-(7-fluoro-1H-indol-5-yl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
   Show/Hide
C26H34F4N6O2S
 1
1
Ki = 3.66 nM
   TI
   LI
   LO
   TS
CP0938645
4-Methyl-N-(7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-yl)benzenesulfonamide
   Show/Hide
C32H42N4O2S
 1
1
Ki = 3.69 nM
   TI
   LI
   LO
   TS
CP0431181
(4-{2-[(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone
   Show/Hide
C28H36N4O2
 1
1
Ki = 3.72 nM
   TI
   LI
   LO
   TS
CP0508124
7-({2-[4-(1H-Indol-5-ylmethyl)-piperazin-1-yl]-ethyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
   Show/Hide
C28H38N4O
 1
1
Ki = 3.87 nM
   TI
   LI
   LO
   TS
CP0397621
(6S)-6-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C30H44N2O2
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0413984
[4-[2-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]ethyl]piperazin-1-yl]-(1H-indol-5-yl)methanone
   Show/Hide
C25H34N6OS
 1
1
Ki = 4.1 nM
   TI
   LI
   LO
   TS
CP0891588
4-Chloro-N-(7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-yl)benzenesulfonamide
   Show/Hide
C31H39ClN4O2S
 1
1
Ki = 4.13 nM
   TI
   LI
   LO
   TS
CP0514195
(S)-N6-(2-(4-phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
   Show/Hide
C22H33N5S
 1
1
Ki = 4.15 nM
   TI
   LI
   LO
   TS
CP0435906
[4-[2-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]ethyl]piperazin-1-yl]-(1H-indol-3-yl)methanone
   Show/Hide
C25H34N6OS
 1
1
Ki = 4.17 nM
   TI
   LI
   LO
   TS
CP0460982
6-[2-[4-(1H-indol-5-ylmethyl)piperazin-1-yl]ethyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C28H38N4O
 1
1
Ki = 4.17 nM
   TI
   LI
   LO
   TS
CP0530228
4-[(E)-5-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]pent-1-enyl]-2-methoxyphenol
   Show/Hide
C22H31N3O2S
 1
1
Ki = 4.24 nM
   TI
   LI
   LO
   TS
CP0791662
6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
   Show/Hide
C17H27NO
 1
1
Ki = 4.73 nM
   TI
   LI
   LO
   TS
CP0521182
7-({2-[4-(1H-Indol-2-ylmethyl)-piperazin-1-yl]-ethyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
   Show/Hide
C28H38N4O
 1
1
Ki = 4.82 nM
   TI
   LI
   LO
   TS
CP0439503
(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-quinolin-3-ylmethanone
   Show/Hide
C29H36N4O2
 1
1
Ki = 5.18 nM
   TI
   LI
   LO
   TS
CP0388068
Benzofuran-2-yl-(4-{2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-methanone
   Show/Hide
C28H35N3O3
 1
1
Ki = 5.23 nM
   TI
   LI
   LO
   TS
CP0435908
6-[2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]ethyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C28H38N4O
 1
1
Ki = 5.48 nM
   TI
   LI
   LO
   TS
CP0386478
7-(propyl(2-(4-(pyrimidin-2-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C23H33N5O
 1
1
Ki = 6.84 nM
   TI
   LI
   LO
   TS
CP0436355
6-N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-6-N-prop-2-ynyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
   Show/Hide
C22H27Cl2N5S
 1
1
Ki = 7.1 nM
   TI
   LI
   LO
   TS
CP0381261
(6S)-6-[nonyl(propyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C22H37NO
 1
1
Ki = 7.3 nM
   TI
   LI
   LO
   TS
CP0386479
7-((2-(4-(4-iodophenyl)piperazin-1-yl)-ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C25H34IN3O
 1
1
Ki = 7.66 nM
   TI
   LI
   LO
   TS
CP0435907
6-N-[2-[4-(1H-indol-5-ylmethyl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
   Show/Hide
C25H36N6S
 1
1
Ki = 8.07 nM
   TI
   LI
   LO
   TS
CP0912857
N-(7-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-yl)-4-(trifluoromethyl)benzenesulfonamide
   Show/Hide
C32H39F3N4O2S
 1
1
Ki = 8.64 nM
   TI
   LI
   LO
   TS
CP0380254
6-N-[2-[4-[(4-fluoro-1H-indol-3-yl)methyl]piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
   Show/Hide
C27H36F4N6O2S
 1
1
Ki = 8.87 nM
   TI
   LI
   LO
   TS
CP0893977
rac-4'-(4-(4-((2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)-(propyl)amino)-butyl)piperazin-1-yl)-[1,1'-biphenyl]-3-ol
   Show/Hide
C30H41N5OS
 1
1
Ki = 9.43 nM
   TI
   LI
   LO
   TS
CP0913101
rac-(4-(2-((2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)-(propyl)amino)ethyl)-piperazin-1-yl)(biphenyl-4-yl)-methanone
   Show/Hide
C29H37N5OS
 1
1
Ki = 9.58 nM
   TI
   LI
   LO
   TS
CP0499441
(6S)-6-[12-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]dodecyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C38H60N2O2
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0523646
6-[2-[4-(1H-indol-5-yl)piperazin-1-yl]ethyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C27H36N4O
 1
1
Ki = 10.4 nM
   TI
   LI
   LO
   TS
CP0917515
N-(2-(4-Phenylpiperazin-1-yl)ethyl)-N-propyl-5,6,7,8-tetrahydro-1H-benzo[f]indol-7-amine
   Show/Hide
C27H36N4
 1
1
Ki = 10.7 nM
   TI
   LI
   LO
   TS
CP0460588
4-[3-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]propyl]benzene-1,2-diol
   Show/Hide
C19H27N3O2S
 1
1
Ki = 11.9 nM
   TI
   LI
   LO
   TS
CP0474382
6-N-[2-[4-[(5-fluoro-1H-indol-3-yl)methyl]piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
   Show/Hide
C27H36F4N6O2S
 1
1
Ki = 12.1 nM
   TI
   LI
   LO
   TS
CP0428163
6-N-[4-(4-phenylpiperazin-1-yl)butyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
   Show/Hide
C24H37N5S
 1
1
Ki = 12.4 nM
   TI
   LI
   LO
   TS
CP0388834
6-N-[2-[4-[(5-bromo-1H-indol-3-yl)methyl]piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
   Show/Hide
C27H36BrF3N6O2S
 1
1
Ki = 12.9 nM
   TI
   LI
   LO
   TS
CP0420648
6-N-[2-[4-[(4-chloro-1H-indol-3-yl)methyl]piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
   Show/Hide
C27H36ClF3N6O2S
 1
1
Ki = 13.8 nM
   TI
   LI
   LO
   TS
CP0411949
7-(propyl(2-(4-(pyridin-4-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C24H34N4O
 1
1
Ki = 14.1 nM
   TI
   LI
   LO
   TS
CP0385333
2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-[2-[4-(4-chloro-1H-indol-5-yl)piperazin-1-yl]ethyl]amino]acetonitrile;2,2,2-trifluoroacetic acid
   Show/Hide
C25H29ClF3N7O2S
 1
1
Ki = 14.4 nM
   TI
   LI
   LO
   TS
CP0482678
4-[3-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]propyl]-2-methoxyphenol
   Show/Hide
C20H29N3O2S
 1
1
Ki = 15.8 nM
   TI
   LI
   LO
   TS
CP0381602
(6R)-6-N-[2-[4-(1H-indol-5-yl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
   Show/Hide
C24H34N6S
 1
1
Ki = 15.9 nM
   TI
   LI
   LO
   TS
CP0564082
6-N-[2-[4-[(5-methoxy-1H-indol-3-yl)methyl]piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
   Show/Hide
C28H39F3N6O3S
 1
1
Ki = 15.9 nM
   TI
   LI
   LO
   TS
CP0445267
[4-[2-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]ethyl]piperazin-1-yl]-(5-hydroxy-1H-indol-3-yl)methanone
   Show/Hide
C25H34N6O2S
 1
1
Ki = 16.8 nM
   TI
   LI
   LO
   TS
CP0891590
(-)-(S)-6-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-yl 4-methoxybenzenesulfonate
   Show/Hide
C32H41N3O4S
 1
1
Ki = 17.6 nM
   TI
   LI
   LO
   TS
CP0452361
(R)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C25H35N3O
 1
1
Ki = 18.4 nM
   TI
   LI
   LO
   TS
CP0912859
N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-propyl-5,6,7,8-tetrahydro-1H-naphtho[2,3-d]imidazol-6-amine
   Show/Hide
C27H37N5O
 1
1
Ki = 19.7 nM
   TI
   LI
   LO
   TS
CP0913100
(R)-(+)-4'-(4-(2-((2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)(propyl)amino)ethyl)piperazin-1-yl)biphenyl-3-ol
   Show/Hide
C28H37N5OS
 1
1
Ki = 19.7 nM
   TI
   LI
   LO
   TS
CP0380694
(2R)-2-N-[2-(4-phenylpiperazin-1-yl)ethyl]-2-N-propyl-1,2,3,4-tetrahydronaphthalene-2,7-diamine
   Show/Hide
C25H36N4
 1
1
Ki = 20.2 nM
   TI
   LI
   LO
   TS
CP0434347
2-N-[2-(4-phenylpiperazin-1-yl)ethyl]-2-N-propyl-1,2,3,4-tetrahydronaphthalene-2,7-diamine
   Show/Hide
C25H36N4
 1
1
Ki = 22.2 nM
   TI
   LI
   LO
   TS
CP0460585
4-[(E)-5-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]pent-1-enyl]-2-methoxyphenol
   Show/Hide
C22H31N3O2S
 1
1
Ki = 22.3 nM
   TI
   LI
   LO
   TS
CP0476542
(6S)-6-[9-phenylnonyl(propyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C28H41NO
 1
1
Ki = 23 nM
   TI
   LI
   LO
   TS
CP0531726
4-[(Z)-5-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]pent-1-enyl]-2-methoxyphenol
   Show/Hide
C22H31N3O2S
 1
1
Ki = 23.3 nM
   TI
   LI
   LO
   TS
CP0564083
6-N-[2-[4-[(4-methoxy-1H-indol-3-yl)methyl]piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
   Show/Hide
C28H39F3N6O3S
 1
1
Ki = 25 nM
   TI
   LI
   LO
   TS
CP0935414
(R)-7-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-yl 4-methoxybenzenesulfonate
   Show/Hide
C32H41N3O4S
 1
1
Ki = 26.9 nM
   TI
   LI
   LO
   TS
CP0078778
4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one
   Show/Hide
C16H24N2O
 1
1
Ki = 29.3 nM
   TI
   LI
   LO
   TS
CP0499440
(6S)-6-[14-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]tetradecyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
   Show/Hide
C40H64N2O2
 1
1
Ki = 31 nM
   TI
   LI
   LO
   TS
CP0955872
(S)-6-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-yl 4-methylbenzenesulfonate
   Show/Hide
C32H41N3O3S
 1
1
Ki = 32 nM
   TI
   LI
   LO
   TS
CP0453132
6-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-6-N-prop-2-ynyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
   Show/Hide
C23H31N5OS
 1
1
Ki = 34.8 nM
   TI
   LI
   LO
   TS
CP0491811
(S)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
   Show/Hide
C25H35N3O
 1
1
Ki = 38.6 nM
   TI
   LI
   LO
   TS
CP0482679
4-[(E)-3-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]prop-1-enyl]-2-methoxyphenol
   Show/Hide
C20H27N3O2S
 1
1
Ki = 39.1 nM
   TI
   LI
   LO
   TS
CP0428160
N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-propyl-4,5,6,7-tetrahydro-1,2,3-benzoselenadiazol-6-amine
   Show/Hide
C21H31N5Se
 1
1
Ki = 40.7 nM
   TI
   LI
   LO
   TS
CP0491809
(R)-N6-(2-(4-phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
   Show/Hide
C22H33N5S
 1
1
Ki = 44 nM
   TI
   LI
   LO
   TS
CP0891592
(-)-(S)-N2-(2-(4-Phenylpiperazin-1-yl)ethyl)-N2-propyl-1,2,3,4-tetrahydronaphthalene-2,7-diamine
   Show/Hide
C25H36N4
 1
1
Ki = 45.5 nM
   TI
   LI
   LO
   TS
CP0434973
N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-propyl-4,5,6,7-tetrahydro-1H-indazol-5-amine
   Show/Hide
C22H33N5
 1
1
Ki = 46.7 nM
   TI
   LI
   LO
   TS
CP0513305
[4-[2-[[(6R)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]-(1H-indol-3-yl)methanone
   Show/Hide
C25H34N6OS
 1
1
Ki = 48.2 nM
   TI
   LI
   LO
   TS
CP0461028
[4-[2-[[(6R)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]-(1H-indol-5-yl)methanone
   Show/Hide
C25H34N6OS
 1
1
Ki = 52.8 nM
   TI
   LI
   LO
   TS
CP0435909
[4-[2-[[(6R)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
   Show/Hide
C25H34N6OS
 1
1
Ki = 54.1 nM
   TI
   LI
   LO
   TS
CP0955877
N-(2-(4-Phenylpiperazin-1-yl)ethyl)-N-propyl-6,7,8,9-tetrahydro-1H-naphtho[1,2-d]imidazol-8-amine
   Show/Hide
C26H35N5
 1
1
Ki = 54.1 nM
   TI
   LI
   LO
   TS
CP0912858
N-(2-(4-Phenylpiperazin-1-yl)ethyl)-N-propyl-5,6,7,8-tetrahydro-1H-naphtho[2,3-d]imidazol-6-amine
   Show/Hide
C26H35N5
 1
1
Ki = 60 nM
   TI
   LI
   LO
   TS
CP0848876
rac-4'-(4-(2-((2-Amino-5,6,7,8-tetrahydroquinazolin-6-yl)-(propyl)amino)ethyl)piperazin-1-yl)-[1,1'-biphenyl]-3-ol
   Show/Hide
C29H38N6O
 1
1
Ki = 67 nM
   TI
   LI
   LO
   TS
CP0491810
(4aS,10bS)-4-(2-(4-phenylpiperazin-1-yl)ethyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-9-ol
   Show/Hide
C25H33N3O
 1
1
Ki = 72.2 nM
   TI
   LI
   LO
   TS
CP0491812
(+)-(4aR,10aR)-trans-4-(2-(4-Phenylpiperazin-1-yl)ethyl)-1,2,3,4,4a,5,6,10b-octa-hydrobenzo[f]quinolin-7-ol
   Show/Hide
C25H33N3O
 1
1
Ki = 89.3 nM
   TI
   LI
   LO
   TS
CP0310336
(+/-)-trans-4-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-7-ol
   Show/Hide
C16H23NO
 1
1
Ki = 96 nM
   TI
   LI
   LO
   TS
CP0036921
3-HYDROXYTYRAMINE HYDROCHLORIDE
   Show/Hide
C8H11NO2
 1
1
Ki = 101 nM
   TI
   LI
   LO
   TS
CP0491807
(+/-)-trans-1-[4-(4-Phenylpiperazin-1-yl)butyl]-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol
   Show/Hide
C27H37N3O
 1
1
Ki = 102 nM
   TI
   LI
   LO
   TS
CP0935413
N-(7-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-yl)benzamide
   Show/Hide
C32H40N4O
 1
1
Ki = 109 nM
   TI
   LI
   LO
   TS
CP0906081
6-((2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydro-1H-naphtho-[2,3-d]imidazole-2(3H)-thione
   Show/Hide
C27H37N5OS
 1
1
Ki = 112 nM
   TI
   LI
   LO
   TS
CP0431899
N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-propyl-4,5,6,7-tetrahydro-1,2-benzoxazol-5-amine
   Show/Hide
C22H32N4O
 1
1
Ki = 155 nM
   TI
   LI
   LO
   TS
CP0428162
N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-propyl-4,5,6,7-tetrahydro-1,2,3-benzothiadiazol-6-amine
   Show/Hide
C21H31N5S
 1
1
Ki = 160 nM
   TI
   LI
   LO
   TS
CP0374537
(+/-)-trans-1-{2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl}-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-ol
   Show/Hide
C25H31Cl2N3O
 1
1
Ki = 168 nM
   TI
   LI
   LO
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CP0891587
N-(7-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-yl)-acetamide
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C27H38N4O
 1
1
Ki = 174 nM
   TI
   LI
   LO
   TS
CP0372791
(+/-)-cis-1-{2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl}-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol
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C25H31Cl2N3O
 1
1
Ki = 187 nM
   TI
   LI
   LO
   TS
CP0428159
N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-propyl-4,5,6,7-tetrahydro-1H-indazol-6-amine
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C22H33N5
 1
1
Ki = 188 nM
   TI
   LI
   LO
   TS
CP0848663
6-((2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydro-1H-naphtho-[2,3-d]imidazol-2(3H)-one
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C27H37N5O2
 1
1
Ki = 195 nM
   TI
   LI
   LO
   TS
CP0431900
N-[2-(4-phenylpiperazin-1-yl)ethyl]-N-propyl-4,5,6,7-tetrahydro-2,1-benzoxazol-5-amine
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C22H32N4O
 1
1
Ki = 254 nM
   TI
   LI
   LO
   TS
CP0491813
(+/-)-trans-1-{2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl}-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol
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C25H31Cl2N3O
 1
1
Ki = 256 nM
   TI
   LI
   LO
   TS
CP0504116
(+/-)-trans-1-Propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-ol
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C16H23NO
 1
1
Ki = 395 nM
   TI
   LI
   LO
   TS
CP0372792
(+/-)-cis-1-[2-(4-Phenylpiperazin-1-yl)ethyl]-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol
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C25H33N3O
 1
1
Ki = 419 nM
   TI
   LI
   LO
   TS
CP0517511
(+/-)-trans-1-[2-(4-Phenylpiperazin-1-yl)ethyl]-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol
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C25H33N3O
 1
1
Ki = 473 nM
   TI
   LI
   LO
   TS
CP0372788
(+/-)-trans-1-[2-(4-Phenylpiperazin-1-yl)ethyl]-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-ol
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C25H33N3O
 1
1
Ki = 736 nM
   TI
   LI
   LO
   TS
CP0891591
N6-(2-(4-Phenylpiperazin-1-yl)ethyl)-N6-propyl-5,6,7,8-tetrahydro-1H-naphtho[2,3-d]imidazole-2,6-diamine
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C26H38N6
 1
1
Ki = 1790 nM
   TI
   LI
   LO
   TS