Brief Information of the Compound and Protein
Compound Name
(+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
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PubChem ID
CID: 1219
SID: 14847634
Canonical SMILES
CCCN(CCC)C1CCc2ccc(O)cc2C1
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Compound Formula C16H25NO
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P19020
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  2
1
IC50 = 1.11 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.25 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 2.35 nM
   TI
   LI
   LO
   TS
2
Ki = 6.19 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 1.18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 0.67 nM
2 Ki = 2.9 nM