| Compound ID |
Compound Name |
Compound Formula |
|
CP0017043
|
(2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Show/Hide
|
C18H18ClIN6O4
|
5
|
| 1 |
EC50 = 4.1 nM
|
|
|
| 2 |
ED50 = 100 nM
|
|
|
| 3 |
Ki = 0.33 nM
|
|
|
| 4 |
Ki = 0.637 nM
|
|
|
| 5 |
Ki = 1.1 nM
|
|
|
|
CP0570120
|
(1S,2R,3S,4R,5S)-4-[2-[2-(5-fluorothiophen-2-yl)ethynyl]-6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C28H27FN6O5S
|
2
|
| 1 |
EC50 = 23.7 nM
|
|
|
| 2 |
EC50 = 24.9 nM
|
|
|
|
CP0543701
|
(1S,2R,3S,4R,5S)-4-[2-(cyclopropylmethoxy)-6-[2-(3-hydroxy-4-methoxyphenyl)ethylamino]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C26H32N6O6
|
2
|
| 1 |
EC50 = 31.3 nM
|
|
|
| 2 |
EC50 = 37.1 nM
|
|
|
|
CP0550445
|
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-[(4-hydroxy-3-methoxyphenyl)methylamino]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C27H25ClN6O5S
|
2
|
| 1 |
EC50 = 35 nM
|
|
|
| 2 |
EC50 = 36 nM
|
|
|
|
CP0543700
|
(1S,2R,3S,4R,5S)-2,3-dihydroxy-4-[6-[2-(3-hydroxy-4-methoxyphenyl)ethylamino]-2-methoxypurin-9-yl]-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C23H28N6O6
|
2
|
| 1 |
EC50 = 38.5 nM
|
|
|
| 2 |
EC50 = 50.2 nM
|
|
|
|
CP0575564
|
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C28H27ClN6O5S
|
2
|
| 1 |
EC50 = 39.7 nM
|
|
|
| 2 |
EC50 = 43.9 nM
|
|
|
|
CP0552075
|
(1S,2R,3S,4R,5S)-2,3-dihydroxy-4-[6-[2-(3-hydroxy-4-methoxyphenyl)ethylamino]-2-(2-methylpropoxy)purin-9-yl]-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C26H34N6O6
|
2
|
| 1 |
EC50 = 45.9 nM
|
|
|
| 2 |
EC50 = 51.5 nM
|
|
|
|
CP0568779
|
(1S,2R,3S,4R,5S)-2,3-dihydroxy-4-[6-[2-(3-hydroxy-4-methoxyphenyl)ethylamino]-2-(3-methylbutoxy)purin-9-yl]-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C27H36N6O6
|
2
|
| 1 |
EC50 = 49.4 nM
|
|
|
| 2 |
EC50 = 69.2 nM
|
|
|
|
CP0547240
|
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(2-phenylethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C27H25ClN6O3S
|
2
|
| 1 |
EC50 = 64 nM
|
|
|
| 2 |
EC50 = 64.9 nM
|
|
|
|
CP0579110
|
(1S,2R,3S,4R,5S)-4-[6-[2-(3,4-dimethoxyphenyl)ethylamino]-2-iodopurin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C23H27IN6O5
|
2
|
| 1 |
EC50 = 66.4 nM
|
|
|
| 2 |
EC50 = 73.6 nM
|
|
|
|
CP0039348
|
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C12H16N6O4
|
8
|
| 1 |
EC50 = 154 nM
|
|
|
| 2 |
EC50 = 177 nM
|
|
|
| 3 |
Ki = 10.2 nM
|
|
|
| 4 |
Ki = 10.6 nM
|
|
|
| 5 |
Ki = 11 nM
|
|
|
| 6 |
Ki = 19.6 nM
|
|
|
| 7 |
Ki = 44.1 nM
|
|
|
| 8 |
Ki = 89.13 nM
|
|
|
|
CP0228686
|
(1R,2R,3S,4R,5S)-4-[6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C28H27N5O4
|
2
|
| 1 |
EC50 = 158 nM
|
|
|
| 2 |
Ki = 10.9 nM
|
|
|
|
CP0418017
|
(1R,2R,3S,4R,5S)-4-[2-[2-(5-bromothiophen-2-yl)ethynyl]-6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C26H24BrN5O4S
|
2
|
| 1 |
EC50 = 692 nM
|
|
|
| 2 |
Ki = 3.24 nM
|
|
|
|
CP0543862
|
(1S,2R,3S,4R,5S)-4-[2-(3-cyclohexylpropoxy)-6-[2-(3-hydroxy-4-methoxyphenyl)ethylamino]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C31H42N6O6
|
2
|
| 1 |
EC50 = 841 nM
|
|
|
| 2 |
EC50 = 1430 nM
|
|
|
|
CP0169100
|
(1R,2R,3S,4R,5S)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C18H22ClN5O2
|
1
|
| 1 |
EC50 = 1370 nM
|
|
|
|
CP0418004
|
(1R,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(2-phenylethylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C25H22ClN5O2S
|
2
|
| 1 |
EC50 = 2410 nM
|
|
|
| 2 |
Ki = 8.17 nM
|
|
|
|
CP0018686
|
(2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
Show/Hide
|
C18H19IN6O4
|
9
|
| 1 |
ED50 = 28 nM
|
|
|
| 2 |
IC50 = 0.6 nM
|
|
|
| 3 |
IC50 = 1.2 nM
|
|
|
| 4 |
Ki = 0.215 nM
|
|
|
| 5 |
Ki = 0.37 nM
|
|
|
| 6 |
Ki = 0.84 nM
|
|
|
| 7 |
Ki = 0.96 nM
|
|
|
| 8 |
Ki = 1.1 nM
|
|
|
| 9 |
Ki = 1.2 nM
|
|
|
|
CP0408095
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-(2-(4-methoxyphenyl)ethynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C23H26N6O5
|
2
|
| 1 |
ED50 = 125 nM
|
|
|
| 2 |
Ki = 0.748 nM
|
|
|
|
CP0106716
|
5-Butyl-8-(4-methoxy-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C17H18N6O
|
2
|
| 1 |
IC50 < 0.1 nM
|
|
|
| 2 |
Ki = 0.18 nM
|
|
|
|
CP0037138
|
5-Butyl-8-(4-ethoxy-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C18H20N6O
|
2
|
| 1 |
IC50 = 0.21 nM
|
|
|
| 2 |
Ki = 0.9 nM
|
|
|
|
CP0186843
|
5-Butyl-8-(3-methoxy-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C17H18N6O
|
1
|
| 1 |
IC50 = 0.22 nM
|
|
|
|
CP0079106
|
8-Phenyl-5-propyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C15H14N6
|
1
|
| 1 |
IC50 = 0.23 nM
|
|
|
|
CP0044678
|
5-Butyl-8-(4-fluoro-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C16H15FN6
|
1
|
| 1 |
IC50 = 0.25 nM
|
|
|
|
CP0163517
|
5-Butyl-8-phenyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C16H16N6
|
1
|
| 1 |
IC50 = 0.25 nM
|
|
|
|
CP0195839
|
5-Butyl-8-m-tolyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C17H18N6
|
1
|
| 1 |
IC50 = 0.27 nM
|
|
|
|
CP0170975
|
5-Butyl-8-(2-chloro-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C16H15ClN6
|
1
|
| 1 |
IC50 = 0.29 nM
|
|
|
|
CP0229698
|
5-Pentyl-8-phenyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C17H18N6
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0288431
|
5-Butyl-8-(4-propoxy-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C19H22N6O
|
2
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
Ki = 0.51 nM
|
|
|
|
CP0298635
|
5-Butyl-8-p-tolyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C17H18N6
|
1
|
| 1 |
IC50 = 0.33 nM
|
|
|
|
CP0171066
|
5,8-Diphenyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C18H12N6
|
1
|
| 1 |
IC50 = 0.41 nM
|
|
|
|
CP0306273
|
5-Butyl-8-(4-chloro-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C16H15ClN6
|
1
|
| 1 |
IC50 = 0.41 nM
|
|
|
|
CP0035888
|
5-Ethyl-8-phenyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C14H12N6
|
1
|
| 1 |
IC50 = 0.45 nM
|
|
|
|
CP0045100
|
5-Hexyl-8-phenyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C18H20N6
|
1
|
| 1 |
IC50 = 0.61 nM
|
|
|
|
CP0306274
|
5-Butyl-8-(4-trifluoromethyl-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C17H15F3N6
|
2
|
| 1 |
IC50 = 0.61 nM
|
|
|
| 2 |
Ki = 0.95 nM
|
|
|
|
CP0311179
|
4-(5-butyl-1H-[1,2,4]triazolo[5,1-f]purin-8-yl)-N,N-dimethylaniline
Show/Hide
|
C18H21N7
|
2
|
| 1 |
IC50 = 0.67 nM
|
|
|
| 2 |
Ki = 1.25 nM
|
|
|
|
CP0447721
|
8-Biphenyl-4-yl-5-(2-methoxy-ethyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C21H18N6O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0056273
|
5-Methyl-8-phenyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C13H10N6
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0795225
|
1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
Show/Hide
|
C19H16N2O2S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0163764
|
5-Butyl-8-(3-chloro-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C16H15ClN6
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0371451
|
5-Butyl-8-(3,4,5-trimethoxy-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C19H22N6O3
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0059697
|
5-Butyl-8-pyridin-3-yl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C15H15N7
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0309913
|
5-Butyl-8-(4-tert-butyl-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C20H24N6
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0104551
|
4-(5-Butyl-3H-[1,2,4]triazolo[5,1-i]purin-8-yl)-phenol
Show/Hide
|
C16H16N6O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0259454
|
8-(4-Bromo-phenyl)-5-butyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C16H15BrN6
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0399728
|
5-Butyl-2-(4-fluoro-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H15FN6
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0488154
|
5-Butyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H16N6
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0330212
|
5-Butyl-8-(4-methylsulfanyl-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C17H18N6S
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0399696
|
5-Butyl-2-p-tolyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H18N6
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0447991
|
2-Phenyl-5-propyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C15H14N6
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0471941
|
5-Butyl-2-(4-chloro-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H15ClN6
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0337596
|
8-Biphenyl-4-yl-5-butyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C22H20N6
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0488144
|
4-[8-(4-Chloro-phenyl)-3H-[1,2,4]triazolo[5,1-i]purin-5-yl]-butyric acid
Show/Hide
|
C16H13ClN6O2
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0330211
|
5-Butyl-8-furan-2-yl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C14H14N6O
|
1
|
| 1 |
IC50 = 5.9 nM
|
|
|
|
CP0409696
|
5-Ethyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C14H12N6
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0376682
|
2-(4-Bromo-phenyl)-5-butyl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H17BrN4
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0509127
|
4-(8-Biphenyl-4-yl-3H-[1,2,4]triazolo[5,1-i]purin-5-yl)-butyric acid
Show/Hide
|
C22H18N6O2
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0399680
|
5-(8-Biphenyl-4-yl-3H-[1,2,4]triazolo[5,1-i]purin-5-yl)-pentanoic acid
Show/Hide
|
C23H20N6O2
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0399729
|
4-(5-Butyl-[1,2,4]triazolo[1,5-c]quinazolin-2-yl)-phenol
Show/Hide
|
C19H18N4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0432913
|
5-Butyl-2-(4-methoxy-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H18N6O
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0451750
|
5-Butyl-2-(4-ethoxy-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C18H20N6O
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0492267
|
5-Butyl-2-(2-chloro-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H15ClN6
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0527672
|
5-Butyl-2-(3-chloro-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H15ClN6
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0494587
|
5-Butyl-2-(4-ethyl-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C18H20N6
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0448274
|
3-(8-Biphenyl-4-yl-3H-[1,2,4]triazolo[5,1-i]purin-5-yl)-propionic acid
Show/Hide
|
C21H16N6O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0409500
|
2-(4-Bromo-phenyl)-5-butyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H15BrN6
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0498250
|
2-(4-Bromo-phenyl)-5-butyl-9-chloro-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H16BrClN4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0447720
|
5-Butyl-2-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H17ClN4
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0374666
|
5-Butyl-2-(4-fluoro-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H17FN4
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0383693
|
5-Butyl-9-chloro-2-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H16Cl2N4
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0403741
|
5-Butyl-9-chloro-2-(4-methoxy-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C20H19ClN4O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0467086
|
5-Butyl-8-chloro-2-(4-methoxy-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C20H19ClN4O
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0492838
|
5-Butyl-2-p-tolyl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C20H20N4
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0415011
|
5-Butyl-2-(4-ethoxy-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C21H22N4O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0405939
|
5-Butyl-2-(4-propyl-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C19H22N6
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0375149
|
5-Butyl-9-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H17ClN4
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0383677
|
5-Butyl-8-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H17ClN4
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0497284
|
5-Butyl-8-methyl-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C20H20N4
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0492338
|
5-Butyl-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C17H16N4O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0461870
|
5-Butyl-2-(4-trifluoromethyl-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H15F3N6
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0502421
|
2-Biphenyl-4-yl-5-butyl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C25H22N4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0504196
|
5-Butyl-2-(4-tert-butyl-phenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C20H24N6
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0496700
|
5-Butyl-2-(4-methoxy-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C20H20N4O
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0372284
|
5-Butyl-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H18N4
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0453503
|
5-Butyl-8-chloro-2-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H16Cl2N4
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0495165
|
8-cyclopentyl-2-(3-methoxyphenoxy)-1-propyl-7H-purin-6-one
Show/Hide
|
C20H24N4O3
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0373629
|
2-Biphenyl-4-yl-5-butyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
|
C22H20N6
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0409161
|
5-Butyl-2-(4-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C20H17F3N4
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0646059
|
5-Butyl-8-methyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C11H14N6
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0720062
|
8-Benzyl-5-butyl-3H-[1,2,4]triazolo[5,1-i]purine
Show/Hide
|
C17H18N6
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0493534
|
5-Butyl-10-chloro-2-phenyl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C19H17ClN4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0572048
|
5-[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-8-yl]-1-methylpyridin-2-one
Show/Hide
|
C15H12N6O2
|
1
|
| 1 |
IC50 = 2023 nM
|
|
|
|
CP0201120
|
8-cyclopentyl-2-(3,4-difluorophenoxy)-1-propyl-7H-purin-6-one
Show/Hide
|
C19H20F2N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0039042
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2-phenylacetamide
Show/Hide
|
C21H14ClN5O2
|
5
|
| 1 |
Kd = 0.07762 nM
|
|
|
| 2 |
Ki = 0.1148 nM
|
|
|
| 3 |
Ki = 0.65 nM
|
|
|
| 4 |
Ki = 2.97 nM
|
|
|
| 5 |
Ki = 3.24 nM
|
|
|
|
CP0944878
|
N-[4-(3,5-dimethylphenyl)-5-(4-pyridyl)thiazol-2-yl]-5-tritio-pyridine-3-carboxamide
Show/Hide
|
C22H18N4OS
|
1
|
| 1 |
Kd = 0.55 nM
|
|
|
|
CP0543063
|
3-phenyl-7-(3,4,5-trimethoxyanilino)-1H-pyrazolo[3,4-c]pyridine-5-carbonitrile
Show/Hide
|
C22H19N5O3
|
1
|
| 1 |
Kd = 10 nM
|
|
|
|
CP0544746
|
7-anilino-3-phenyl-1H-pyrazolo[3,4-c]pyridine-5-carbonitrile
Show/Hide
|
C19H13N5
|
1
|
| 1 |
Kd = 26.3 nM
|
|
|
|
CP0550419
|
N-benzyl-1-methyl-3-phenylpyrazolo[3,4-d]pyridazin-7-amine
Show/Hide
|
C19H17N5
|
2
|
| 1 |
Kd = 54.95 nM
|
|
|
| 2 |
Ki = 12.88 nM
|
|
|
|
CP0543064
|
3-phenyl-N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-7-amine
Show/Hide
|
C21H20N4O3
|
1
|
| 1 |
Kd = 74.13 nM
|
|
|
|
CP0551633
|
2-anilino-N-(5-anilino-1-methylpyrazolo[3,4-c]pyridin-3-yl)acetamide
Show/Hide
|
C21H20N6O
|
1
|
| 1 |
Kd = 77.62 nM
|
|
|
|
CP0537767
|
5-chloro-3-phenyl-N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-7-amine
Show/Hide
|
C21H19ClN4O3
|
1
|
| 1 |
Kd = 85.11 nM
|
|
|
|
CP0537770
|
3-phenyl-5-[(pyridin-3-ylmethylamino)methyl]-N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-7-amine
Show/Hide
|
C28H28N6O3
|
1
|
| 1 |
Kd = 100 nM
|
|
|
|
CP0546190
|
5-[(benzylamino)methyl]-3-phenyl-N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-7-amine
Show/Hide
|
C29H29N5O3
|
1
|
| 1 |
Kd = 186.21 nM
|
|
|
|
CP0544745
|
5-(aminomethyl)-3-phenyl-N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-7-amine
Show/Hide
|
C22H23N5O3
|
1
|
| 1 |
Kd = 257.04 nM
|
|
|
|
CP0546210
|
5-[[(1-methylpiperidin-4-yl)methylamino]methyl]-3-phenyl-N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-7-amine
Show/Hide
|
C29H36N6O3
|
1
|
| 1 |
Kd = 275.42 nM
|
|
|
|
CP0546191
|
2-anilino-N-(5-anilino-1H-pyrazolo[3,4-c]pyridin-3-yl)acetamide
Show/Hide
|
C20H18N6O
|
1
|
| 1 |
Kd = 354.81 nM
|
|
|
|
CP0849514
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(pyridin-4-yl)urea hydrochloride
Show/Hide
|
C17H14ClN9O2
|
1
|
| 1 |
Ki = 0.014 nM
|
|
|
|
CP0713932
|
2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester
Show/Hide
|
C31H27NO4
|
2
|
| 1 |
Ki = 0.0314 nM
|
|
|
| 2 |
Ki = 22.2 nM
|
|
|
|
CP0376341
|
1-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-pyridin-4-yl-urea
Show/Hide
|
C17H13N9O2
|
1
|
| 1 |
Ki = 0.046 nM
|
|
|
|
CP0864089
|
7-Methyl-2-phenyl-4-((E)-styryl)-1,4-dihydro-quinoline-3,6-dicarboxylic acid diethyl ester
Show/Hide
|
C30H29NO4
|
1
|
| 1 |
Ki = 0.11 nM
|
|
|
|
CP0047375
|
1-(8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-p-tolyl-urea
Show/Hide
|
C20H18N8O2
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0437409
|
1-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
|
C21H15ClN6O3
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0333052
|
1-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-phenylurea
Show/Hide
|
C20H18N8O2
|
1
|
| 1 |
Ki = 0.15 nM
|
|
|
|
CP0273529
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-phenylurea
Show/Hide
|
C18H14N8O2
|
1
|
| 1 |
Ki = 0.16 nM
|
|
|
|
CP0348520
|
1-(8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-phenyl-urea
Show/Hide
|
C19H16N8O2
|
1
|
| 1 |
Ki = 0.18 nM
|
|
|
|
CP0047376
|
1-(4-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C19H15ClN8O2
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0282756
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C19H16N8O3
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0079503
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-phenyl-urea
Show/Hide
|
C21H20N8O2
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0079506
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-p-tolyl-urea
Show/Hide
|
C22H22N8O2
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0348518
|
1-(benzo[d][1,3]dioxol-5-yl)-3-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea
Show/Hide
|
C19H14N8O4
|
1
|
| 1 |
Ki = 0.24 nM
|
|
|
|
CP0079483
|
1-(benzo[d][1,3]dioxol-5-yl)-3-(8-ethyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea
Show/Hide
|
C20H16N8O4
|
1
|
| 1 |
Ki = 0.27 nM
|
|
|
|
CP0308558
|
1-(8-ethyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C20H18N8O3
|
2
|
| 1 |
Ki = 0.28 nM
|
|
|
| 2 |
Ki = 0.6 nM
|
|
|
|
CP0053428
|
1-[4-(furan-2-yl)-11-propyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
|
C21H20N8O3
|
2
|
| 1 |
Ki = 0.29 nM
|
|
|
| 2 |
Ki = 0.8 nM
|
|
|
|
CP0047377
|
1-(4-Fluoro-phenyl)-3-(2-furan-2-yl-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C20H17FN8O2
|
1
|
| 1 |
Ki = 0.29 nM
|
|
|
|
CP0210735
|
1-(4-Chloro-phenyl)-3-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C18H13ClN8O2
|
1
|
| 1 |
Ki = 0.29 nM
|
|
|
|
CP0250680
|
1-(benzo[d][1,3]dioxol-5-yl)-3-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea
Show/Hide
|
C21H18N8O4
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0291713
|
1-(2-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C19H15ClN8O2
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0333051
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-p-tolylurea
Show/Hide
|
C19H16N8O2
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0220980
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
|
C22H22N8O3
|
1
|
| 1 |
Ki = 0.32 nM
|
|
|
|
CP0448655
|
2-[(2R,3R,4S)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]-N-methylacetamide
Show/Hide
|
C19H20ClIN6O4
|
1
|
| 1 |
Ki = 0.33 nM
|
|
|
|
CP0047382
|
1-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(2-methoxyphenyl)urea
Show/Hide
|
C21H20N8O3
|
1
|
| 1 |
Ki = 0.34 nM
|
|
|
|
CP0133195
|
1-(4-Fluoro-phenyl)-3-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C18H13FN8O2
|
1
|
| 1 |
Ki = 0.34 nM
|
|
|
|
CP0248930
|
1-(4-Chloro-phenyl)-3-(2-furan-2-yl-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C20H17ClN8O2
|
1
|
| 1 |
Ki = 0.34 nM
|
|
|
|
CP0390573
|
5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H13N9O2
|
1
|
| 1 |
Ki = 0.35 nM
|
|
|
|
CP0048970
|
(S)-N-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-2-phenyl-propionamide
Show/Hide
|
C22H16ClN5O2
|
1
|
| 1 |
Ki = 0.362 nM
|
|
|
|
CP0258307
|
1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C19H15BrN8O2
|
1
|
| 1 |
Ki = 0.37 nM
|
|
|
|
CP0113085
|
1-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-p-tolylurea
Show/Hide
|
C21H20N8O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0237635
|
1-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-methoxyphenyl)urea
Show/Hide
|
C21H20N8O3
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0264646
|
1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C18H13ClN8O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0079507
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-chloro-phenyl)-urea
Show/Hide
|
C21H19ClN8O2
|
1
|
| 1 |
Ki = 0.43 nM
|
|
|
|
CP0390571
|
5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H13N9O2
|
1
|
| 1 |
Ki = 0.44 nM
|
|
|
|
CP0187298
|
1-(4-Bromo-phenyl)-3-(2-furan-2-yl-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C20H17BrN8O2
|
1
|
| 1 |
Ki = 0.45 nM
|
|
|
|
CP0116392
|
1-(4-Bromo-phenyl)-3-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C18H13BrN8O2
|
1
|
| 1 |
Ki = 0.46 nM
|
|
|
|
CP0182270
|
(R)-N-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-2-phenyl-propionamide
Show/Hide
|
C22H16ClN5O2
|
1
|
| 1 |
Ki = 0.468 nM
|
|
|
|
CP0248931
|
1-(3-chlorophenyl)-3-[2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]urea
Show/Hide
|
C20H17ClN8O2
|
2
|
| 1 |
Ki = 0.49 nM
|
|
|
| 2 |
Ki = 0.91 nM
|
|
|
|
CP0277666
|
1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea
Show/Hide
|
C22H20N8O4
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0871056
|
5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine hydrochloride
Show/Hide
|
C17H14ClN9O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0277567
|
1-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-(trifluoromethyl)phenyl)urea
Show/Hide
|
C21H17F3N8O2
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0381502
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((S)-3-hydroxyoct-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C22H32N6O5
|
1
|
| 1 |
Ki = 0.542 nM
|
|
|
|
CP0881058
|
5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine hydrochloride
Show/Hide
|
C17H14ClN9O2
|
1
|
| 1 |
Ki = 0.55 nM
|
|
|
|
CP0237628
|
1-(8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(2-methoxy-phenyl)-urea
Show/Hide
|
C20H18N8O3
|
1
|
| 1 |
Ki = 0.56 nM
|
|
|
|
CP0133191
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(2-methoxy-phenyl)-urea
Show/Hide
|
C22H22N8O3
|
1
|
| 1 |
Ki = 0.57 nM
|
|
|
|
CP0185816
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2,2-diphenylacetamide
Show/Hide
|
C27H18ClN5O2
|
1
|
| 1 |
Ki = 0.586 nM
|
|
|
|
CP0092135
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-chloro-phenyl)-urea
Show/Hide
|
C21H19ClN8O2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0187296
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-methoxy-phenyl)-urea
Show/Hide
|
C22H22N8O3
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0079480
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(2-methoxyphenyl)urea
Show/Hide
|
C19H16N8O3
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0453295
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((R)-3-hydroxyoct-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C22H32N6O5
|
1
|
| 1 |
Ki = 0.709 nM
|
|
|
|
CP0333031
|
1-(2-Chloro-phenyl)-3-(2-furan-2-yl-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C20H17ClN8O2
|
1
|
| 1 |
Ki = 0.71 nM
|
|
|
|
CP0116391
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-trifluoromethyl-phenyl)-urea
Show/Hide
|
C22H19F3N8O2
|
1
|
| 1 |
Ki = 0.72 nM
|
|
|
|
CP0237626
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-(trifluoromethyl)phenyl)urea
Show/Hide
|
C19H13F3N8O2
|
1
|
| 1 |
Ki = 0.74 nM
|
|
|
|
CP0451808
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((R,S)-3-hydroxy-3-(4-methoxyphenyl)prop-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C24H28N6O6
|
1
|
| 1 |
Ki = 0.754 nM
|
|
|
|
CP0435534
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((R,S)-3-hydroxy-3-phenylprop-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C23H26N6O5
|
1
|
| 1 |
Ki = 0.763 nM
|
|
|
|
CP0133194
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-methoxyphenyl)urea
Show/Hide
|
C19H16N8O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0290657
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-fluoro-phenyl)-urea
Show/Hide
|
C21H19FN8O2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0258311
|
N-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C19H15N7O2
|
1
|
| 1 |
Ki = 0.81 nM
|
|
|
|
CP0053427
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(2-chloro-phenyl)-urea
Show/Hide
|
C21H19ClN8O2
|
1
|
| 1 |
Ki = 0.86 nM
|
|
|
|
CP0210713
|
1-(8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-fluoro-phenyl)-urea
Show/Hide
|
C19H15FN8O2
|
1
|
| 1 |
Ki = 0.86 nM
|
|
|
|
CP0291712
|
1-(8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-methoxy-phenyl)-urea
Show/Hide
|
C20H18N8O3
|
1
|
| 1 |
Ki = 0.86 nM
|
|
|
|
CP0047373
|
1-(2-Chloro-phenyl)-3-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C18H13ClN8O2
|
1
|
| 1 |
Ki = 0.91 nM
|
|
|
|
CP0143977
|
1-(4-Bromo-phenyl)-3-(8-butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C21H19BrN8O2
|
1
|
| 1 |
Ki = 0.91 nM
|
|
|
|
CP0187299
|
1-(8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-trifluoromethyl-phenyl)-urea
Show/Hide
|
C20H15F3N8O2
|
1
|
| 1 |
Ki = 0.97 nM
|
|
|
|
CP0053426
|
N-[4-(furan-2-yl)-11-propyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C21H19N7O2
|
1
|
| 1 |
Ki = 1.01 nM
|
|
|
|
CP0432709
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-(hex-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C20H28N6O4
|
1
|
| 1 |
Ki = 1.02 nM
|
|
|
|
CP0487550
|
2-[(2R,3R,4S)-3,4-dihydroxy-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]oxolan-2-yl]-N-methylacetamide
Show/Hide
|
C19H21IN6O4
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0079509
|
N-[11-butyl-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C22H21N7O2
|
1
|
| 1 |
Ki = 1.11 nM
|
|
|
|
CP0376070
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((R,S)-3-hydroxy-3-(3-methoxyphenyl)prop-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C24H28N6O6
|
1
|
| 1 |
Ki = 1.17 nM
|
|
|
|
CP0441884
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-(6-hydroxyhex-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C20H28N6O5
|
1
|
| 1 |
Ki = 1.28 nM
|
|
|
|
CP0424936
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((R,S)-3-hydroxy-3-(2-nitrophenyl)prop-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C23H25N7O7
|
1
|
| 1 |
Ki = 1.29 nM
|
|
|
|
CP0849513
|
2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]-N-methylpyridinium iodide
Show/Hide
|
C18H16IN9O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0376071
|
(2S,3S,4R,5R)-5-(2-((R,S)-3-cyclohexyl-3-hydroxyprop-1-ynyl)-6-(ethylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C23H32N6O5
|
1
|
| 1 |
Ki = 1.31 nM
|
|
|
|
CP0381503
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-(3-phenylprop-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C23H26N6O4
|
1
|
| 1 |
Ki = 1.35 nM
|
|
|
|
CP0045165
|
1-(2-(furan-2-yl)-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C26H22N8O3
|
1
|
| 1 |
Ki = 1.47 nM
|
|
|
|
CP0376135
|
N-(1-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)benzamide
Show/Hide
|
C22H15N5O2
|
1
|
| 1 |
Ki = 1.47 nM
|
|
|
|
CP0395496
|
5-[6-(4-Amino-3-iodo-benzylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid methylamide
Show/Hide
|
C18H20IN7O4
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0222481
|
1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C19H15ClN8O2
|
2
|
| 1 |
Ki = 1.6 nM
|
|
|
| 2 |
Ki = 2.09 nM
|
|
|
|
CP0432711
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((R)-3-hydroxybut-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C18H24N6O5
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0259712
|
N-[4-(3,5-dimethylphenyl)-5-pyridin-4-yl-1,3-thiazol-2-yl]pyridine-3-carboxamide
Show/Hide
|
C22H18N4OS
|
1
|
| 1 |
Ki = 1.65 nM
|
|
|
|
CP0381594
|
(2S,3S,4R,5R)-5-(2-((R,S)-3-cyclopentyl-3-hydroxyprop-1-ynyl)-6-(ethylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C22H30N6O5
|
1
|
| 1 |
Ki = 1.84 nM
|
|
|
|
CP0503048
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-(2-(1-hydroxycyclohexyl)ethynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C22H30N6O5
|
1
|
| 1 |
Ki = 1.91 nM
|
|
|
|
CP0436562
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((R,S)-3-hydroxy-3-(2-methoxyphenyl)prop-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C24H28N6O6
|
1
|
| 1 |
Ki = 1.98 nM
|
|
|
|
CP0174169
|
N-(1-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)acetamide
Show/Hide
|
C17H13N5O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0435426
|
2-[2-(4-Benzooxazol-2-yl-pyrazol-1-yl)-6-methylamino-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C21H20N8O5
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0440382
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(methylamino)-2-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)-9H-purin-9-yl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C19H20N8O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0485139
|
2-Hydroxymethyl-5-[6-methylamino-2-(4-pyridin-3-yl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H20N8O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0293183
|
2-(furan-2-yl)-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C18H15N7O
|
2
|
| 1 |
Ki = 2.03 nM
|
|
|
| 2 |
Ki = 2785 nM
|
|
|
|
CP0453292
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-(2-(1-hydroxycyclopentyl)ethynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C21H28N6O5
|
1
|
| 1 |
Ki = 2.03 nM
|
|
|
|
CP0432710
|
(R,S)-methyl 3-(3-(6-(ethylamino)-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl)-9H-purin-2-yl)-1-hydroxyprop-2-ynyl)benzoate
Show/Hide
|
C25H28N6O7
|
1
|
| 1 |
Ki = 2.13 nM
|
|
|
|
CP0376072
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((S)-3-hydroxybut-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C18H24N6O5
|
1
|
| 1 |
Ki = 2.22 nM
|
|
|
|
CP0103764
|
(1R,2R,3S,4R,5S)-4-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-1-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C19H19ClIN5O3
|
1
|
| 1 |
Ki = 2.24 nM
|
|
|
|
CP0734534
|
(R)-4-methyl-8-ethyl-2-phenyl-4,5,7,8-tetrahydro-1H-imidazo[2,1-i]purin-5-one
Show/Hide
|
C16H17N5O
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0408090
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-(4-hydroxybut-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C18H24N6O5
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0376044
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-(5-phenylpent-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C25H30N6O4
|
1
|
| 1 |
Ki = 2.42 nM
|
|
|
|
CP0079484
|
1-(3,4-Dichloro-phenyl)-3-(2-furan-2-yl-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C20H16Cl2N8O2
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0730689
|
3-ethyl 5-(4-nitrobenzyl)2-methyl-6-phenyl-4-(phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C31H26N2O6
|
1
|
| 1 |
Ki = 2.69 nM
|
|
|
|
CP0079482
|
1-(3,4-Dichloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C19H14Cl2N8O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0442194
|
2-Hydroxymethyl-5-[6-methylamino-2-(4-quinolin-2-yl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C23H22N8O4
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0453033
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]benzamide
Show/Hide
|
C20H12ClN5O2
|
1
|
| 1 |
Ki = 3.03 nM
|
|
|
|
CP0774802
|
2-Ethoxymethyl-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H22IN5O4
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0047372
|
1-(3,4-Dichloro-phenyl)-3-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C18H12Cl2N8O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0270742
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(methylamino)-2-(phenylethynyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
Show/Hide
|
C19H19N5O4
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0376069
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((R,S)-3-hydroxy-3-(3-nitrophenyl)prop-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C23H25N7O7
|
1
|
| 1 |
Ki = 3.45 nM
|
|
|
|
CP0382460
|
5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H14N8O2S
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0382462
|
2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]pyridinium N-oxide
Show/Hide
|
C17H13N9O3
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0213333
|
2-(4-Amino-phenyl)-N-(9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-acetamide
Show/Hide
|
C21H15ClN6O2
|
1
|
| 1 |
Ki = 3.56 nM
|
|
|
|
CP0079505
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3,4-dichloro-phenyl)-urea
Show/Hide
|
C21H18Cl2N8O2
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0539797
|
N-(1-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-2-phenylacetamide
Show/Hide
|
C23H17N5O2
|
1
|
| 1 |
Ki = 3.75 nM
|
|
|
|
CP0459773
|
(2S,3S,4R,5R)-5-(2-(2-cyclohexenylethynyl)-6-(ethylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C22H28N6O4
|
1
|
| 1 |
Ki = 3.77 nM
|
|
|
|
CP0324288
|
1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-quinazolin-4-yl)-urea
Show/Hide
|
C21H17N5O2
|
2
|
| 1 |
Ki = 4 nM
|
|
|
| 2 |
Ki = 4030 nM
|
|
|
|
CP0404822
|
1-Benzyl-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C19H18N4O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0420524
|
2-(4-methoxyphenyl)-6-phenyl-9H-purine
Show/Hide
|
C18H14N4O
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0376073
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-iodo-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C14H19IN6O4
|
1
|
| 1 |
Ki = 4.03 nM
|
|
|
|
CP0163656
|
(1R,2R,3S,4R,5S)-1-Hydroxymethyl-4-[6-(3-iodo-benzylamino)-purin-9-yl]-bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C19H20IN5O3
|
1
|
| 1 |
Ki = 4.13 nM
|
|
|
|
CP0675753
|
2-[6-(3-Iodo-benzylamino)-purin-9-yl]-5-methoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H20IN5O4
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0453968
|
1-Benzyl-3-cyclopropylmethyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C20H18N4O2
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0500293
|
4,6-Diethyl-5-ethylsulfanylcarbonyl-2-phenyl-nicotinic acid 2-fluoro-ethyl ester
Show/Hide
|
C21H24FNO3S
|
1
|
| 1 |
Ki = 4.22 nM
|
|
|
|
CP0442091
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-((R,S)-4-hydroxypent-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C19H26N6O5
|
1
|
| 1 |
Ki = 4.58 nM
|
|
|
|
CP0529959
|
(1R,2R,3S,4R,5S)-4-[2-[2-(3-fluorophenyl)ethynyl]-6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C28H26FN5O4
|
1
|
| 1 |
Ki = 4.63 nM
|
|
|
|
CP0431496
|
3-Allyl-1-benzyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C19H16N4O2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0853216
|
3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]-N-methylpyridinium iodide
Show/Hide
|
C18H16IN9O2
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0418019
|
(1R,2R,3S,4R,5S)-4-[2-[2-(2-fluorophenyl)ethynyl]-6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C28H26FN5O4
|
1
|
| 1 |
Ki = 5.42 nM
|
|
|
|
CP0435425
|
2-Hydroxymethyl-5-[6-methylamino-2-(4-pyridin-4-yl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H20N8O4
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0408091
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(ethylamino)-2-(oct-1-ynyl)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C22H32N6O4
|
1
|
| 1 |
Ki = 6.05 nM
|
|
|
|
CP0543930
|
N-[4-(3-iodo-5-methylphenyl)-5-pyridin-4-yl-1,3-thiazol-2-yl]pyridine-3-carboxamide
Show/Hide
|
C21H15IN4OS
|
1
|
| 1 |
Ki = 6.12 nM
|
|
|
|
CP0408163
|
(2S,3S,4R,5R)-5-(2-(dec-1-ynyl)-6-(ethylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C24H36N6O4
|
1
|
| 1 |
Ki = 6.2 nM
|
|
|
|
CP0384104
|
1-Benzyl-3-isobutyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0532493
|
N-[4-(3-bromo-5-methylphenyl)-5-pyridin-4-yl-1,3-thiazol-2-yl]pyridine-3-carboxamide
Show/Hide
|
C21H15BrN4OS
|
1
|
| 1 |
Ki = 6.34 nM
|
|
|
|
CP0217091
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Show/Hide
|
C11H14N6O4
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0571147
|
3-O-ethyl 5-O-[(3-nitrophenyl)methyl] 2-methyl-6-phenyl-4-(2-phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C31H26N2O6
|
2
|
| 1 |
Ki = 6.49 nM
|
|
|
| 2 |
Ki = 10.6 nM
|
|
|
|
CP0542587
|
(1R,2R,3S,4R,5S)-4-[2-[2-(4-fluorophenyl)ethynyl]-6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C28H26FN5O4
|
1
|
| 1 |
Ki = 6.51 nM
|
|
|
|
CP0529957
|
(1R,2R,3S,4R,5S)-4-[6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]-2-(2-pyridin-3-ylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C27H26N6O4
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0554683
|
tert-butyl N-[3-[[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]amino]-3-oxopropyl]carbamate
Show/Hide
|
C21H21ClN6O4
|
1
|
| 1 |
Ki = 6.71 nM
|
|
|
|
CP0438038
|
(1R,2R,3S,4R,5S)-4-[6-[2-(3-hydroxy-4-methoxyphenyl)ethylamino]-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C28H27N5O4
|
1
|
| 1 |
Ki = 6.85 nM
|
|
|
|
CP0386106
|
N-(2,6-diphenylpyrimidin-4-yl)acetamide
Show/Hide
|
C18H15N3O
|
1
|
| 1 |
Ki = 6.88 nM
|
|
|
|
CP0037176
|
(2R,3R,4S,5R)-2-(6-(3-iodobenzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C17H18IN5O4
|
3
|
| 1 |
Ki = 6.9 nM
|
|
|
| 2 |
Ki = 27.7 nM
|
|
|
| 3 |
Ki = 28 nM
|
|
|
|
CP0102094
|
(2R,3R,4S,5R)-2-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C17H17ClIN5O4
|
1
|
| 1 |
Ki = 7.2 nM
|
|
|
|
CP0378817
|
2-[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]-N-[(2-chloro-3-iodophenyl)methyl]acetamide
Show/Hide
|
C18H18ClIN6O4
|
1
|
| 1 |
Ki = 7.2 nM
|
|
|
|
CP0817451
|
2-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-5-methoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H19ClIN5O4
|
1
|
| 1 |
Ki = 7.3 nM
|
|
|
|
CP0837761
|
2-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-5-ethoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H21ClIN5O4
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0403014
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]propanamide
Show/Hide
|
C16H12ClN5O2
|
1
|
| 1 |
Ki = 7.66 nM
|
|
|
|
CP0508088
|
(2R,3R,4S,5R)-2-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-5-isoxazol-3-yl-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H16ClIN6O4
|
1
|
| 1 |
Ki = 7.8 nM
|
|
|
|
CP0514407
|
(3S,4R,5R)-2-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-5-(1,2-oxazol-3-yl)oxolane-3,4-diol
Show/Hide
|
C19H16ClIN6O4
|
1
|
| 1 |
Ki = 7.8 nM
|
|
|
|
CP0047864
|
4,6-Diethyl-5-ethylsulfanylcarbonyl-2-phenyl-nicotinic acid propyl ester
Show/Hide
|
C22H27NO3S
|
1
|
| 1 |
Ki = 8.29 nM
|
|
|
|
CP0376879
|
1-(4-Methoxy-benzyl)-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C20H20N4O3
|
1
|
| 1 |
Ki = 8.3 nM
|
|
|
|
CP0856068
|
2-[6-(3-Iodo-benzylamino)-purin-9-yl]-5-methylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H20IN5O3S
|
1
|
| 1 |
Ki = 8.78 nM
|
|
|
|
CP0438039
|
(1R,2R,3S,4R,5S)-4-[6-[2-(3-fluoro-4-hydroxyphenyl)ethylamino]-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C27H24FN5O3
|
1
|
| 1 |
Ki = 9.03 nM
|
|
|
|
CP0836852
|
2-Cyclopropoxymethyl-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H22IN5O4
|
1
|
| 1 |
Ki = 9.1 nM
|
|
|
|
CP0418018
|
(1R,2R,3S,4R,5S)-4-[6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]-2-iodopurin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C20H22IN5O4
|
1
|
| 1 |
Ki = 9.1 nM
|
|
|
|
CP0442576
|
2,6-bis(4-tolyl)-9H-purine
Show/Hide
|
C19H16N4
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
|
CP0467287
|
2-tolyl-6-phenyl-9H-purine
Show/Hide
|
C18H14N4
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0464716
|
8-isopropyl-2,6-diphenyl-9H-purine
Show/Hide
|
C20H18N4
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0470973
|
(1R,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C26H24ClN5O4S
|
1
|
| 1 |
Ki = 9.52 nM
|
|
|
|
CP0409365
|
6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid 3-fluoro-propyl ester
Show/Hide
|
C23H28FNO3S
|
1
|
| 1 |
Ki = 9.67 nM
|
|
|
|
CP0573405
|
2-[(2R,3R,4S)-3,4-dihydroxy-5-[6-[2-(4-sulfamoylphenyl)hydrazinyl]purin-9-yl]oxolan-2-yl]-N-ethylacetamide
Show/Hide
|
C19H24N8O6S
|
1
|
| 1 |
Ki = 9.73 nM
|
|
|
|
CP0415097
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[7-[(3-iodophenyl)methylamino]-5-nitroimidazo[4,5-b]pyridin-3-yl]oxolane-3,4-diol
Show/Hide
|
C18H18IN5O6
|
1
|
| 1 |
Ki = 9.8 nM
|
|
|
|
CP0935338
|
7-Ethyl-4-methyl-2-phenyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one
Show/Hide
|
C16H17N5O
|
1
|
| 1 |
Ki = 9.8 nM
|
|
|
|
CP0376533
|
1-Benzyl-7-methoxy-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C20H20N4O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0382461
|
5-[[(5-methyl-thiophen-2-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H14N8O2S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0382463
|
3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]pyridinium N-oxide
Show/Hide
|
C17H13N9O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0485968
|
2-{2-[4-(4-Chloro-phenyl)-pyrazol-1-yl]-6-methylamino-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H20ClN7O4
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0386629
|
5-[[(3-furyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H12N8O3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0432956
|
5-Oxo-2-phenyl-4-propyl-7,8-dihydro-5H-thiopyrano[4,3-b]pyridine-3-carboxylic acid ethyl ester
Show/Hide
|
C20H21NO3S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0500276
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[(3-iodophenyl)methylamino]-2-nitropurin-9-yl]oxolane-3,4-diol
Show/Hide
|
C17H17IN6O6
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0475229
|
5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C20H14N8O3
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0529960
|
(1R,2R,3S,4R,5S)-4-[2-[2-(3,4-difluorophenyl)ethynyl]-6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C28H25F2N5O4
|
1
|
| 1 |
Ki = 12.8 nM
|
|
|
|
CP0258379
|
9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]triazolo[5,1-a][2,7]naphthyridine-6-carboxylic acid methyl ester
Show/Hide
|
C18H16N4O2
|
2
|
| 1 |
Ki = 13 nM
|
|
|
| 2 |
Ki = 170 nM
|
|
|
|
CP0333181
|
1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C25H19ClN8O2
|
1
|
| 1 |
Ki = 13.28 nM
|
|
|
|
CP0044275
|
9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine
Show/Hide
|
C13H8ClN5O
|
4
|
| 1 |
Ki = 13.8 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
| 3 |
Ki = 140 nM
|
|
|
| 4 |
Ki = 143 nM
|
|
|
|
CP0448307
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]acetamide
Show/Hide
|
C15H10ClN5O2
|
1
|
| 1 |
Ki = 13.9 nM
|
|
|
|
CP0490671
|
1-Benzyl-3-prop-2-ynyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C19H14N4O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0470989
|
(1R,2R,3S,4R,5S)-4-[6-[2-(4-aminophenyl)ethylamino]-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C27H26N6O2
|
1
|
| 1 |
Ki = 14.2 nM
|
|
|
|
CP0190102
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2-(4-methoxyphenyl)acetamide
Show/Hide
|
C22H16ClN5O3
|
1
|
| 1 |
Ki = 14.4 nM
|
|
|
|
CP0850123
|
2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-methylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C17H23N5O3S
|
1
|
| 1 |
Ki = 14.5 nM
|
|
|
|
CP0501112
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]butanamide
Show/Hide
|
C17H14ClN5O2
|
1
|
| 1 |
Ki = 14.6 nM
|
|
|
|
CP0442189
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(2-(4-(4-methoxyphenyl)-1H-pyrazol-1-yl)-6-(methylamino)-9H-purin-9-yl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C21H23N7O5
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0661276
|
2-(6-Amino-2-chloro-purin-9-yl)-5-ethoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C12H16ClN5O4
|
1
|
| 1 |
Ki = 15.1 nM
|
|
|
|
CP0375610
|
N-(1-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)propanamide
Show/Hide
|
C18H15N5O2
|
1
|
| 1 |
Ki = 15.8 nM
|
|
|
|
CP0464616
|
2-(4-Methoxy-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C16H12N4O3
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0390572
|
5-[[(2-furyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H12N8O3
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0270772
|
(2R,3R,4S,5R)-2-(6-amino-2-(phenylethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Show/Hide
|
C18H17N5O4
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0470988
|
(1R,2R,3S,4R,5S)-4-[6-[2-(3,4-dimethoxyphenyl)ethylamino]-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C29H29N5O4
|
1
|
| 1 |
Ki = 16.3 nM
|
|
|
|
CP0199236
|
(2R,3R,4S,5R)-2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C16H21N5O4
|
1
|
| 1 |
Ki = 16.9 nM
|
|
|
|
CP0405061
|
4-Methoxy-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
Show/Hide
|
C22H17N3O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0467289
|
8-propyl-2,6-diphenyl-9H-purine
Show/Hide
|
C20H18N4
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0935446
|
2-Ethylsulfanylmethyl-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H22IN5O3S
|
1
|
| 1 |
Ki = 17.5 nM
|
|
|
|
CP0356282
|
5-Amino-3-(4-methoxy-phenyl)-thiazolo[3,2-a]pyrimidin-7-one
Show/Hide
|
C13H11N3O2S
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0918853
|
3-Ethyl-10-oxo-1-propyl-10H-9-oxa-4-aza-phenanthrene-2-carbothioic acid S-(2,2,2-trifluoro-ethyl) ester
Show/Hide
|
C23H26F3NO3S
|
1
|
| 1 |
Ki = 18.1 nM
|
|
|
|
CP0210711
|
6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid propyl ester
Show/Hide
|
C23H29NO3S
|
2
|
| 1 |
Ki = 18.9 nM
|
|
|
| 2 |
Ki = 43.9 nM
|
|
|
|
CP0533723
|
methyl (E)-3-[3-methyl-5-[2-(pyridine-3-carbonylamino)-5-pyridin-4-yl-1,3-thiazol-4-yl]phenyl]prop-2-enoate
Show/Hide
|
C25H20N4O3S
|
1
|
| 1 |
Ki = 18.9 nM
|
|
|
|
CP0485548
|
1-[9-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-methylamino-9H-purin-2-yl]-1H-pyrazole-4-carboxylic acid propylamide
Show/Hide
|
C18H24N8O5
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0250678
|
1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C27H24N8O3
|
1
|
| 1 |
Ki = 19.81 nM
|
|
|
|
CP0415082
|
(2R,3R,4S,5R)-2-(2-Chloro-6-methoxyamino-purin-9-yl)-5-vinyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C12H14ClN5O4
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0184463
|
4,6-Diethyl-5-ethylsulfanylcarbonyl-2-phenyl-nicotinic acid ethyl ester
Show/Hide
|
C21H25NO3S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0407653
|
(1R,2R,3S,4R,5S)-4-[6-(2-phenylethylamino)-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C27H25N5O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0381593
|
(R,S)-3-(3-(6-(ethylamino)-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl)-9H-purin-2-yl)-1-hydroxyprop-2-ynyl)benzoic acid
Show/Hide
|
C24H26N6O7
|
1
|
| 1 |
Ki = 20.1 nM
|
|
|
|
CP0684553
|
2-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-5-cyclopropoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H21ClIN5O4
|
1
|
| 1 |
Ki = 20.5 nM
|
|
|
|
CP0390570
|
4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]pyridinium N-oxide
Show/Hide
|
C17H13N9O3
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0942196
|
(S)-2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester
Show/Hide
|
C31H27NO4
|
1
|
| 1 |
Ki = 21.3 nM
|
|
|
|
CP0374207
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]pentanamide
Show/Hide
|
C18H16ClN5O2
|
1
|
| 1 |
Ki = 21.5 nM
|
|
|
|
CP0183373
|
tert-butyl N-[5-[[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]amino]-5-oxopentyl]carbamate
Show/Hide
|
C23H25ClN6O4
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0395969
|
N-(2,6-diphenylpyrimidin-4-yl)propanamide
Show/Hide
|
C19H17N3O
|
1
|
| 1 |
Ki = 22.4 nM
|
|
|
|
CP0461141
|
3-O-benzyl 5-O-ethyl 2-cyclobutyl-6-methyl-4-(2-phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C29H29NO4
|
1
|
| 1 |
Ki = 22.5 nM
|
|
|
|
CP0378308
|
6-Ethyl-5-ethylsulfanylcarbonyl-2-(2-fluoro-phenyl)-4-propyl-nicotinic acid propyl ester
Show/Hide
|
C23H28FNO3S
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0211418
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-cyclobutyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C14H18N6O4
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0798185
|
2-(6-Amino-purin-9-yl)-5-ethoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C12H17N5O4
|
1
|
| 1 |
Ki = 23.3 nM
|
|
|
|
CP0197846
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-3-phenylpropanamide
Show/Hide
|
C22H16ClN5O2
|
1
|
| 1 |
Ki = 23.6 nM
|
|
|
|
CP0410536
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-3-iodobenzamide
Show/Hide
|
C20H11ClIN5O2
|
1
|
| 1 |
Ki = 23.8 nM
|
|
|
|
CP0309505
|
2-((1H-imidazol-2-yl)methylthio)-6-amino-4-(4-methoxyphenyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C18H14N6OS
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0430482
|
2-p-Tolyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C16H12N4O2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0401492
|
4-(3-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)ureido)benzenesulfonic acid
Show/Hide
|
C18H14N8O5S
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0385992
|
N-(2,6-diphenylpyrimidin-4-yl)cyclopropanecarboxamide
Show/Hide
|
C20H17N3O
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0104008
|
N-(2-aminoethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
Show/Hide
|
C21H28N6O4
|
2
|
| 1 |
Ki = 25.6 nM
|
|
|
| 2 |
Ki = 110 nM
|
|
|
|
CP0559862
|
(2R,3R,4S,5S)-2-(2-Chloro-6-methoxyamino-purin-9-yl)-5-chloromethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C11H13Cl2N5O4
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0570386
|
5-bromo-N-[4-(3,5-dimethylphenyl)-5-pyridin-4-yl-1,3-thiazol-2-yl]pyridine-3-carboxamide
Show/Hide
|
C22H17BrN4OS
|
1
|
| 1 |
Ki = 26.6 nM
|
|
|
|
CP0805930
|
2-(6-Amino-2-chloro-purin-9-yl)-5-cyclopropoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C13H16ClN5O4
|
1
|
| 1 |
Ki = 26.7 nM
|
|
|
|
CP0530353
|
4-Methoxy-N-(2-phenyl-quinazolin-4-yl)-benzamide
Show/Hide
|
C22H17N3O2
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0381591
|
(2S,3S,4R,5R)-5-(2-(2-(1-aminocyclohexyl)ethynyl)-6-(ethylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C22H31N7O4
|
1
|
| 1 |
Ki = 27.2 nM
|
|
|
|
CP0405558
|
4-(cyclopentylamino)-2-m-tolyl-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one
Show/Hide
|
C21H21N5O
|
1
|
| 1 |
Ki = 27.5 nM
|
|
|
|
CP0410707
|
3-O-benzyl 5-O-ethyl 2-cyclopropyl-6-methyl-4-(2-phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C28H27NO4
|
1
|
| 1 |
Ki = 27.7 nM
|
|
|
|
CP0847039
|
4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]-N-methylpyridinium iodide
Show/Hide
|
C18H16IN9O2
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0661365
|
2-(6-Amino-2-chloro-purin-9-yl)-5-methoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C11H14ClN5O4
|
1
|
| 1 |
Ki = 28.3 nM
|
|
|
|
CP0436594
|
4-Amino-2-m-tolyl-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C16H13N5O
|
1
|
| 1 |
Ki = 28.5 nM
|
|
|
|
CP0449300
|
6-Ethyl-5-ethylsulfanylcarbonyl-2-(3-fluoro-phenyl)-4-propyl-nicotinic acid propyl ester
Show/Hide
|
C23H28FNO3S
|
1
|
| 1 |
Ki = 28.9 nM
|
|
|
|
CP0040261
|
BW-A1433
Show/Hide
|
C20H22N4O4
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0382067
|
4-(3-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)ureido)benzenesulfonic acid
Show/Hide
|
C20H18N8O5S
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0511411
|
N-[6-(1,3-benzodioxol-5-yl)-2-phenylpyrimidin-4-yl]cyclopropanecarboxamide
Show/Hide
|
C21H17N3O3
|
1
|
| 1 |
Ki = 30.7 nM
|
|
|
|
CP0508444
|
(2R,3R,4S,5R)-2-(2-Chloro-6-methoxyamino-purin-9-yl)-5-isoxazol-3-yl-tetrahydro-furan-3,4-diol
Show/Hide
|
C13H13ClN6O5
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0498528
|
(3S,4R,5R)-2-[2-chloro-6-[(3-methoxyphenyl)methylamino]purin-9-yl]-5-(1,2-oxazol-3-yl)oxolane-3,4-diol
Show/Hide
|
C20H19ClN6O5
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0856049
|
N-(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-3-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl]-acrylamide
Show/Hide
|
C26H28N6O5
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0394117
|
6-Ethyl-5-ethylsulfanylcarbonyl-2-(4-fluoro-phenyl)-4-propyl-nicotinic acid propyl ester
Show/Hide
|
C23H28FNO3S
|
1
|
| 1 |
Ki = 31.1 nM
|
|
|
|
CP0379088
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-cyclopentyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C15H20N6O4
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0148209
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2-(3-chlorophenyl)acetamide
Show/Hide
|
C21H13Cl2N5O2
|
1
|
| 1 |
Ki = 32.1 nM
|
|
|
|
CP0773499
|
2-(6-Cyclopentylamino-purin-9-yl)-5-ethoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C17H25N5O4
|
1
|
| 1 |
Ki = 32.3 nM
|
|
|
|
CP0894506
|
2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-ethylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H25N5O3S
|
1
|
| 1 |
Ki = 32.3 nM
|
|
|
|
CP0358127
|
tert-butyl N-[4-[[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]amino]-4-oxobutyl]carbamate
Show/Hide
|
C22H23ClN6O4
|
1
|
| 1 |
Ki = 32.9 nM
|
|
|
|
CP0223184
|
tert-butyl N-[6-[[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]amino]-6-oxohexyl]carbamate
Show/Hide
|
C24H27ClN6O4
|
1
|
| 1 |
Ki = 33.8 nM
|
|
|
|
CP0441204
|
1-Benzyl-7-phenyl-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C25H22N4O2
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0451651
|
8-cyclopentyl-2,6-diphenyl-9H-purine
Show/Hide
|
C22H20N4
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0535446
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methoxyamino)-2-nitropurin-9-yl]oxolane-3,4-diol
Show/Hide
|
C11H14N6O7
|
1
|
| 1 |
Ki = 35.8 nM
|
|
|
|
CP0529956
|
(1R,2R,3S,4R,5S)-4-[6-[2-(3-fluorophenyl)ethylamino]-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C27H24FN5O2
|
1
|
| 1 |
Ki = 35.9 nM
|
|
|
|
CP0431290
|
1-Benzyl-3-ethyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C18H16N4O2
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0520921
|
5-Methyl-2-phenyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C16H12N4O2
|
1
|
| 1 |
Ki = 36.6 nM
|
|
|
|
CP0424017
|
(1R,2R,3S,4R,5S)-4-[2-[2-(2-chlorophenyl)ethynyl]-6-(2-phenylethylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C27H24ClN5O2
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0420523
|
2,6-diphenyl-9H-purine
Show/Hide
|
C17H12N4
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0720635
|
2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C15H23N7O4
|
1
|
| 1 |
Ki = 38.3 nM
|
|
|
|
CP0441668
|
4-(3-(8-ethyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)ureido)benzenesulfonic acid
Show/Hide
|
C19H16N8O5S
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0377526
|
N-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenoxyacetamide
Show/Hide
|
C27H23N7O3
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0685375
|
5'-O-methyladenosine
Show/Hide
|
C11H15N5O4
|
1
|
| 1 |
Ki = 40.3 nM
|
|
|
|
CP0496791
|
2-Phenyl-4-(3-phenyl-propylamino)-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C24H21N5O
|
1
|
| 1 |
Ki = 40.9 nM
|
|
|
|
CP0367826
|
(2S,3S,4R,5R)-5-(6-Benzylamino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid methylamide
Show/Hide
|
C18H20N6O4
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0520150
|
2-[(2R,3R,4S)-5-[6-(benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]-N-methylacetamide
Show/Hide
|
C19H22N6O4
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0372680
|
(2R,3R,4S,5R)-2-(6-(ethylamino)-2-(4-(4-methoxyphenyl)-1H-pyrazol-1-yl)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C22H25N7O5
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0470978
|
(1R,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-[2-(3-fluorophenyl)ethylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C25H21ClFN5O2S
|
1
|
| 1 |
Ki = 42.2 nM
|
|
|
|
CP0077413
|
(2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C15H20ClN5O4
|
2
|
| 1 |
Ki = 42.3 nM
|
|
|
| 2 |
Ki = 204 nM
|
|
|
|
CP0036755
|
Benzyl-(9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-amine
Show/Hide
|
C20H14ClN5O
|
1
|
| 1 |
Ki = 42.5 nM
|
|
|
|
CP0047370
|
1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea
Show/Hide
|
C26H21ClN8O2
|
1
|
| 1 |
Ki = 42.65 nM
|
|
|
|
CP0198141
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-N-propyloxolane-2-carboxamide
Show/Hide
|
C13H18N6O4
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0391273
|
4-(cyclohexylamino)-2-(3-fluorophenyl)-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one
Show/Hide
|
C21H20FN5O
|
1
|
| 1 |
Ki = 44.2 nM
|
|
|
|
CP0845030
|
2-[6-(3-Iodo-benzylamino)-purin-9-yl]-5-propylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H24IN5O3S
|
1
|
| 1 |
Ki = 44.3 nM
|
|
|
|
CP0178133
|
5-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-pentanoic acid benzyl ester
Show/Hide
|
C26H22ClN5O4
|
1
|
| 1 |
Ki = 44.7 nM
|
|
|
|
CP0761597
|
2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-methoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C16H22ClN5O4
|
1
|
| 1 |
Ki = 44.9 nM
|
|
|
|
CP0431005
|
N-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C26H21N7O2
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0428540
|
4-Amino-2-(4-methoxy-phenyl)-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C16H13N5O2
|
1
|
| 1 |
Ki = 45.3 nM
|
|
|
|
CP0768892
|
2-(6-Amino-purin-9-yl)-5-cyclopropoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C13H17N5O4
|
1
|
| 1 |
Ki = 45.6 nM
|
|
|
|
CP0543967
|
(1R,2R,3S,4R,5S)-4-[6-[2-(4-hydroxyphenyl)ethylamino]-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C27H25N5O3
|
1
|
| 1 |
Ki = 45.6 nM
|
|
|
|
CP0310362
|
tert-butyl N-[(2R)-1-[[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]amino]-1-oxopropan-2-yl]carbamate
Show/Hide
|
C21H21ClN6O4
|
1
|
| 1 |
Ki = 46.3 nM
|
|
|
|
CP0885799
|
2-[6-(3-Iodo-benzylamino)-purin-9-yl]-5-isopropylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H24IN5O3S
|
1
|
| 1 |
Ki = 46.3 nM
|
|
|
|
CP0496583
|
1-Methyl-2-phenyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one
Show/Hide
|
C14H13N5O
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0398582
|
4-(3-(8-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)ureido)benzenesulfonic acid
Show/Hide
|
C21H20N8O5S
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0529965
|
(1R,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-[2-(3,4-difluorophenyl)ethylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C25H20ClF2N5O2S
|
1
|
| 1 |
Ki = 47.1 nM
|
|
|
|
CP0392585
|
4-Amino-2-p-tolyl-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C16H13N5O
|
1
|
| 1 |
Ki = 48.3 nM
|
|
|
|
CP0529958
|
(1R,2R,3S,4R,5S)-4-[6-[2-(3,4-dihydroxyphenyl)ethylamino]-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C27H25N5O4
|
1
|
| 1 |
Ki = 48.8 nM
|
|
|
|
CP0435423
|
1-[9-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-methylamino-9H-purin-2-yl]-1H-pyrazole-4-carboxylic acid ethylamide
Show/Hide
|
C17H22N8O5
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0451652
|
2,6,8-triphenyl-9H-purine
Show/Hide
|
C23H16N4
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0301619
|
2-(4-Amino-3-iodo-phenyl)-N-(9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-acetamide
Show/Hide
|
C21H14ClIN6O2
|
1
|
| 1 |
Ki = 49.3 nM
|
|
|
|
CP0448140
|
N-[4-(furan-2-yl)-11-(3-methylbutyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenoxyacetamide
Show/Hide
|
C23H23N7O3
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0404253
|
3-O-benzyl 5-O-ethyl 2-cyclopentyl-6-methyl-4-(2-phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C30H31NO4
|
1
|
| 1 |
Ki = 50.5 nM
|
|
|
|
CP0374665
|
6-Ethyl-5-(2-hydroxy-ethylsulfanylcarbonyl)-2-phenyl-4-propyl-nicotinic acid propyl ester
Show/Hide
|
C23H29NO4S
|
1
|
| 1 |
Ki = 51.1 nM
|
|
|
|
CP0100535
|
tert-butyl N-[7-[[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]amino]-7-oxoheptyl]carbamate
Show/Hide
|
C25H29ClN6O4
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0433705
|
N-[6-(1,3-benzodioxol-5-yl)-2-phenylpyrimidin-4-yl]butanamide
Show/Hide
|
C21H19N3O3
|
1
|
| 1 |
Ki = 53.9 nM
|
|
|
|
CP0100378
|
methyl 4-[[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]amino]-4-oxobutanoate
Show/Hide
|
C18H14ClN5O4
|
1
|
| 1 |
Ki = 55.1 nM
|
|
|
|
CP0538001
|
6-Ethyl-5-(2-fluoro-ethylsulfanylcarbonyl)-2-phenyl-4-propyl-nicotinic acid propyl ester
Show/Hide
|
C23H28FNO3S
|
1
|
| 1 |
Ki = 55.1 nM
|
|
|
|
CP0430486
|
4-(cyclopentylamino)-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one
Show/Hide
|
C20H19N5O
|
1
|
| 1 |
Ki = 55.4 nM
|
|
|
|
CP0438037
|
(1R,2R,3S,4R,5S)-4-[6-[2-(3-fluorophenyl)ethylamino]-2-[2-(5-fluorothiophen-2-yl)ethynyl]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C25H21F2N5O2S
|
1
|
| 1 |
Ki = 55.8 nM
|
|
|
|
CP0520922
|
2-(4-Chloro-phenyl)-4-cyclohexylamino-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C21H20ClN5O
|
1
|
| 1 |
Ki = 56.1 nM
|
|
|
|
CP0505895
|
5-Amino-pentanoic acid (9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-amide
Show/Hide
|
C18H17ClN6O2
|
1
|
| 1 |
Ki = 57.9 nM
|
|
|
|
CP0915260
|
2-Methyl-6-phenyl-4-((E)-styryl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester
Show/Hide
|
C31H29NO4
|
1
|
| 1 |
Ki = 58.3 nM
|
|
|
|
CP0529962
|
(1R,2R,3S,4R,5S)-4-[6-[2-(3-chlorophenyl)ethylamino]-2-[2-(5-chlorothiophen-2-yl)ethynyl]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C25H21Cl2N5O2S
|
1
|
| 1 |
Ki = 58.4 nM
|
|
|
|
CP0084597
|
7-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-heptanoic acid methyl ester
Show/Hide
|
C22H22ClN5O4
|
1
|
| 1 |
Ki = 59 nM
|
|
|
|
CP0453737
|
6-Ethyl-5-ethylsulfanylcarbonyl-4-(3-fluoro-propyl)-2-phenyl-nicotinic acid propyl ester
Show/Hide
|
C23H28FNO3S
|
1
|
| 1 |
Ki = 59.9 nM
|
|
|
|
CP0372682
|
2-Hydroxymethyl-5-{2-[4-(4-methoxy-phenyl)-pyrazol-1-yl]-6-propylamino-purin-9-yl}-tetrahydro-furan-3,4-diol
Show/Hide
|
C23H27N7O5
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0397463
|
N-(2-acetylphenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
Show/Hide
|
C27H29N5O5
|
1
|
| 1 |
Ki = 61.9 nM
|
|
|
|
CP0148208
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2-(4-iodophenyl)acetamide
Show/Hide
|
C21H13ClIN5O2
|
1
|
| 1 |
Ki = 62.9 nM
|
|
|
|
CP0506675
|
2-(3-Fluoro-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C15H9FN4O2
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0138000
|
2-(5-Bromo-furan-2-yl)-9-chloro-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine
Show/Hide
|
C13H7BrClN5O
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0773644
|
2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-ethoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C17H24ClN5O4
|
1
|
| 1 |
Ki = 67 nM
|
|
|
|
CP0041258
|
(CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmethyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-ylamino]-ethyl}-phenyl)-propionic acid
Show/Hide
|
C23H29N7O6
|
2
|
| 1 |
Ki = 67.1 nM
|
|
|
| 2 |
Ki = 584 nM
|
|
|
|
CP0437678
|
1-(3-Methyl-benzyl)-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0442578
|
2,6-bis(4-chlorophenyl)-9H-purine
Show/Hide
|
C17H10Cl2N4
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0549783
|
N-[4-(3-fluoro-5-methylphenyl)-5-pyridin-4-yl-1,3-thiazol-2-yl]pyridine-3-carboxamide
Show/Hide
|
C21H15FN4OS
|
1
|
| 1 |
Ki = 69.2 nM
|
|
|
|
CP0356445
|
(E)-N-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-3-phenyl-acrylamide
Show/Hide
|
C22H14ClN5O2
|
1
|
| 1 |
Ki = 72.1 nM
|
|
|
|
CP0441716
|
1-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-6-(methylamino)-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide
Show/Hide
|
C16H20N8O5
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0420494
|
5'-Methylthio Adenosine
Show/Hide
|
C16H23N5O3S
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0444120
|
2-Amino-6-(1H-imidazol-2-ylmethylsulfanyl)-4-(3-methoxy-phenyl)-pyridine-3,5-dicarbonitrile
Show/Hide
|
C18H14N6OS
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0739501
|
2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C26H25NO4
|
2
|
| 1 |
Ki = 75 nM
|
|
|
| 2 |
Ki = 76.6 nM
|
|
|
|
CP0854012
|
2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-isopropylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H27N5O3S
|
1
|
| 1 |
Ki = 75.4 nM
|
|
|
|
CP0449390
|
1-Phenyl-3-(3-pyridin-2-yl-isoquinolin-1-yl)-urea
Show/Hide
|
C21H16N4O
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0415060
|
1,3-Dibenzyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C23H18N4O2
|
1
|
| 1 |
Ki = 77 nM
|
|
|
|
CP0439672
|
4-Methoxy-N-(3-phenyl-isoquinolin-1-yl)-benzamide
Show/Hide
|
C23H18N2O2
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0776123
|
2-(6-Cyclopentylamino-purin-9-yl)-5-methoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C16H23N5O4
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0154687
|
N-benzyl-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
Show/Hide
|
C26H29N5O4
|
1
|
| 1 |
Ki = 79.2 nM
|
|
|
|
CP0373207
|
2-Phenyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C15H10N4O2
|
1
|
| 1 |
Ki = 80 nM
|
|
|
|
CP0543988
|
(1R,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-[[(1S,2R)-2-phenylcyclopropyl]amino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C26H22ClN5O2S
|
1
|
| 1 |
Ki = 80.5 nM
|
|
|
|
CP0494971
|
N-[4-[3-[2-(5-chlorothiophen-2-yl)ethynyl]-5-methylphenyl]-5-pyridin-4-yl-1,3-thiazol-2-yl]pyridine-3-carboxamide
Show/Hide
|
C27H17ClN4OS2
|
1
|
| 1 |
Ki = 80.7 nM
|
|
|
|
CP0228719
|
4-Amino-N-(9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-butyramide
Show/Hide
|
C17H15ClN6O2
|
1
|
| 1 |
Ki = 80.8 nM
|
|
|
|
CP0392343
|
N-[4-(furan-2-yl)-11-(3-methylbutyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C23H23N7O2
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0175598
|
4-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-butyric acid
Show/Hide
|
C18H14ClN5O4
|
1
|
| 1 |
Ki = 81.3 nM
|
|
|
|
CP0192113
|
4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide
Show/Hide
|
C16H13N3O2S
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0403839
|
(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-carbamic acid tert-butyl ester
Show/Hide
|
C18H16ClN5O3
|
1
|
| 1 |
Ki = 82.5 nM
|
|
|
|
CP0445180
|
6-Ethyl-5-(3-fluoro-propylsulfanylcarbonyl)-2-phenyl-4-propyl-nicotinic acid propyl ester
Show/Hide
|
C24H30FNO3S
|
1
|
| 1 |
Ki = 82.8 nM
|
|
|
|
CP0348944
|
tert-butyl N-[1-[[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]amino]-1-oxopropan-2-yl]carbamate;methanol
Show/Hide
|
C21H21ClN6O4
|
1
|
| 1 |
Ki = 82.9 nM
|
|
|
|
CP0392406
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-N-methoxyoxolane-2-carboxamide
Show/Hide
|
C11H14N6O5
|
1
|
| 1 |
Ki = 85.3 nM
|
|
|
|
CP0773402
|
2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-cyclopropoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H24ClN5O4
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0918920
|
2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-propylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H27N5O3S
|
1
|
| 1 |
Ki = 88.3 nM
|
|
|
|
CP0405199
|
(2R,3R,4S,5S)-2-[6-(cyclopentylamino)purin-9-yl]-5-(ethylsulfanylmethyl)oxolane-3,4-diol
Show/Hide
|
C17H25N5O3S
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0397632
|
2-[4-(1,3-dibutyl-2,6-dioxo-7H-purin-8-yl)phenoxy]acetic acid
Show/Hide
|
C21H26N4O5
|
1
|
| 1 |
Ki = 90.3 nM
|
|
|
|
CP0521927
|
2-m-Tolyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C16H12N4O2
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0483334
|
2-(4-chlorophenyl)-6-phenyl-9H-purine
Show/Hide
|
C17H11ClN4
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0469564
|
2-[2-(1-Benzyl-1H-pyrazol-4-yl)-6-methylamino-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C21H23N7O4
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0773647
|
2-(6-Cyclopentylamino-purin-9-yl)-5-cyclopropoxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H25N5O4
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0106489
|
2-Amino-4-(3-hydroxy-phenyl)-6-(1H-imidazol-2-ylmethylsulfanyl)-pyridine-3,5-dicarbonitrile
Show/Hide
|
C17H12N6OS
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0438040
|
(1R,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-[2-(3-methylphenyl)ethylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C26H24ClN5O2S
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0435634
|
(2R,3R,4S,5R)-2-(6-(ethylamino)-2-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C20H22N8O4
|
1
|
| 1 |
Ki = 107 nM
|
|
|
|
CP0829636
|
2-Methyl-6-phenyl-4-((E)-styryl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C26H27NO4
|
2
|
| 1 |
Ki = 108 nM
|
|
|
| 2 |
Ki = 110 nM
|
|
|
|
CP0039632
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-cyclopropyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C13H16N6O4
|
1
|
| 1 |
Ki = 108 nM
|
|
|
|
CP0404151
|
(2-Amino-ethyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxymethyl ester
Show/Hide
|
C21H28N6O5
|
1
|
| 1 |
Ki = 108 nM
|
|
|
|
CP0502370
|
6-(2-Benzyloxy-ethyl)-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid propyl ester
Show/Hide
|
C30H35NO4S
|
1
|
| 1 |
Ki = 109 nM
|
|
|
|
CP0485486
|
2-Hydroxymethyl-5-[6-(3-iodo-benzylamino)-2-(4-isoquinolin-1-yl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C29H25IN8O4
|
1
|
| 1 |
Ki = 109 nM
|
|
|
|
CP0376622
|
5-[[(quinolin-2-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C21H15N9O2
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0520140
|
2-(4-Chloro-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C15H9ClN4O2
|
1
|
| 1 |
Ki = 114 nM
|
|
|
|
CP0378502
|
1-Benzyl-3-cyclohexylmethyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
Ki = 114 nM
|
|
|
|
CP0049200
|
(2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C15H21N5O4
|
3
|
| 1 |
Ki = 120 nM
|
|
|
| 2 |
Ki = 280 nM
|
|
|
| 3 |
Ki = 281 nM
|
|
|
|
CP0454450
|
N-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-naphthalen-1-ylacetamide
Show/Hide
|
C30H23N7O2
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0885574
|
N-(2-Acetyl-phenyl)-3-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl]-acrylamide
Show/Hide
|
C28H29N5O4
|
1
|
| 1 |
Ki = 121 nM
|
|
|
|
CP0395252
|
N-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C27H23N7O2
|
1
|
| 1 |
Ki = 121 nM
|
|
|
|
CP0397869
|
4-(2-Acetylsulfanyl-ethyl)-6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-nicotinic acid propyl ester
Show/Hide
|
C24H29NO4S2
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0913593
|
2-(6-Benzylamino-purin-9-yl)-5-methylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H21N5O3S
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0511131
|
4-Hydroxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide(LUF5437)
Show/Hide
|
C15H11N3O2S
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0913589
|
2-(6-Cyclopentylamino-purin-9-yl)-5-isopropylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H27N5O3S
|
1
|
| 1 |
Ki = 137 nM
|
|
|
|
CP0466895
|
2-(4-Chloro-phenyl)-5-methyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C16H11ClN4O2
|
1
|
| 1 |
Ki = 137 nM
|
|
|
|
CP0132091
|
2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)-N-phenylacetamide
Show/Hide
|
C25H27N5O4
|
1
|
| 1 |
Ki = 137 nM
|
|
|
|
CP0453330
|
2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-N-(4-nitro-phenyl)-acetamide (0.43CH3OH)
Show/Hide
|
C25H26N6O6
|
1
|
| 1 |
Ki = 138 nM
|
|
|
|
CP0442579
|
8-cyclohexyl-6-(4-methoxyphenyl)-2-phenyl-9H-purine
Show/Hide
|
C24H24N4O
|
1
|
| 1 |
Ki = 138 nM
|
|
|
|
CP0383695
|
4-Methyl-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide
Show/Hide
|
C16H13N3OS
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0925119
|
2-Methyl-6-phenyl-4-((E)-styryl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-benzyl ester 5-ethyl ester
Show/Hide
|
C31H29NO4
|
1
|
| 1 |
Ki = 142 nM
|
|
|
|
CP0385993
|
N-(2,6-diphenylpyrimidin-4-yl)-2-methylbutanamide
Show/Hide
|
C21H21N3O
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0485957
|
2-[2-(1-Benzyl-1H-pyrazol-4-yl)-6-propylamino-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C23H27N7O4
|
1
|
| 1 |
Ki = 148 nM
|
|
|
|
CP0521929
|
4-Amino-2-(3-fluoro-phenyl)-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C15H10FN5O
|
1
|
| 1 |
Ki = 157 nM
|
|
|
|
CP0430087
|
1-[9-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-methylamino-9H-purin-2-yl]-1H-pyrazole-4-carboxylic acid 4-chloro-benzylamide
Show/Hide
|
C22H23ClN8O5
|
1
|
| 1 |
Ki = 157 nM
|
|
|
|
CP0951060
|
2-(6-Benzylamino-purin-9-yl)-5-ethylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H23N5O3S
|
1
|
| 1 |
Ki = 159 nM
|
|
|
|
CP0515797
|
(2R,3R,4S,5R)-2-[6-(benzylamino)-2-nitropurin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C17H18N6O6
|
1
|
| 1 |
Ki = 163 nM
|
|
|
|
CP0442577
|
2,6-bis(4-methoxyphenyl)-9H-purine
Show/Hide
|
C19H16N4O2
|
1
|
| 1 |
Ki = 165 nM
|
|
|
|
CP0395859
|
N-(2,6-diphenylpyrimidin-4-yl)butanamide
Show/Hide
|
C20H19N3O
|
1
|
| 1 |
Ki = 167 nM
|
|
|
|
CP0841734
|
2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-benzyl ester 5-ethyl ester
Show/Hide
|
C31H27NO4
|
1
|
| 1 |
Ki = 169 nM
|
|
|
|
CP0451630
|
6-Ethyl-5-ethylsulfanylcarbonyl-4-(3-hydroxy-propyl)-2-phenyl-nicotinic acid propyl ester
Show/Hide
|
C23H29NO4S
|
1
|
| 1 |
Ki = 169 nM
|
|
|
|
CP0091562
|
(1R,2R,3S,4R,5S)-4-(6-Cyclopentylamino-purin-9-yl)-1-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C17H23N5O3
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0442192
|
2-Hydroxymethyl-5-[6-(3-iodo-benzylamino)-2-(4-pyridin-2-yl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C25H23IN8O4
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0432967
|
N-(2,6-diphenylpyrimidin-4-yl)cyclopentanecarboxamide
Show/Hide
|
C22H21N3O
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0137011
|
2-((1H-imidazol-2-yl)methylthio)-6-amino-4-phenylpyridine-3,5-dicarbonitrile
Show/Hide
|
C17H12N6S
|
1
|
| 1 |
Ki = 171 nM
|
|
|
|
CP0448565
|
9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]triazolo[5,1-a]isoquinoline-6-carboxylic acid methyl ester
Show/Hide
|
C19H17N3O2
|
1
|
| 1 |
Ki = 172 nM
|
|
|
|
CP0428542
|
4-(cyclopentylamino)-2-(3-fluorophenyl)-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one
Show/Hide
|
C20H18FN5O
|
1
|
| 1 |
Ki = 173 nM
|
|
|
|
CP0405705
|
N-(2,6-diphenylpyrimidin-4-yl)cyclobutanecarboxamide
Show/Hide
|
C21H19N3O
|
1
|
| 1 |
Ki = 178 nM
|
|
|
|
CP0441727
|
2-Cyclohexyl-N-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-ethylamino-9H-purin-2-yl]-acetamide
Show/Hide
|
C20H30N6O5
|
1
|
| 1 |
Ki = 181 nM
|
|
|
|
CP0432044
|
N-[6-(1,3-benzodioxol-5-yl)-2-phenylpyrimidin-4-yl]cyclopentanecarboxamide
Show/Hide
|
C23H21N3O3
|
1
|
| 1 |
Ki = 186 nM
|
|
|
|
CP0890782
|
2-Chloromethyl-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C17H17ClIN5O3
|
1
|
| 1 |
Ki = 188 nM
|
|
|
|
CP0445225
|
6-(2-Acetylsulfanyl-ethyl)-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid ethyl ester
Show/Hide
|
C24H29NO4S2
|
1
|
| 1 |
Ki = 193 nM
|
|
|
|
CP0492429
|
(2R,3R,4S,5S)-2-[6-(cyclopentylamino)purin-9-yl]-5-(propylsulfanylmethyl)oxolane-3,4-diol
Show/Hide
|
C18H27N5O3S
|
1
|
| 1 |
Ki = 193 nM
|
|
|
|
CP0189552
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2,2-diphenylpropanamide
Show/Hide
|
C28H20ClN5O2
|
1
|
| 1 |
Ki = 194 nM
|
|
|
|
CP0498661
|
2-p-Tolyl-1,2-dihydro-5H-[1,2,4]triazolo[4,3-a]quinoxalin-4-one
Show/Hide
|
C16H14N4O
|
1
|
| 1 |
Ki = 197 nM
|
|
|
|
CP0448312
|
N-(3-pyridin-2-ylisoquinolin-1-yl)benzamide
Show/Hide
|
C21H15N3O
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0404844
|
1-Benzyl-7-phenyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C22H16N4O2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0318841
|
8-cyclohexyl-2,6-diphenyl-9H-purine
Show/Hide
|
C23H22N4
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0501139
|
4-Phenethylamino-2-phenyl-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C23H19N5O
|
1
|
| 1 |
Ki = 201 nM
|
|
|
|
CP0457140
|
(2R,3R,4S,5R)-2-(6-amino-2-nitropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C10H12N6O6
|
1
|
| 1 |
Ki = 202 nM
|
|
|
|
CP0378259
|
1-Benzyl-7-methoxy-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C17H14N4O3
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0885034
|
2-(6-Benzylamino-purin-9-yl)-5-isopropylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H25N5O3S
|
1
|
| 1 |
Ki = 211 nM
|
|
|
|
CP0421040
|
(2S,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-N-propan-2-yloxolane-2-carboxamide
Show/Hide
|
C13H18N6O4
|
1
|
| 1 |
Ki = 211 nM
|
|
|
|
CP0084237
|
6-Amino-hexanoic acid (9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-amide
Show/Hide
|
C19H19ClN6O2
|
1
|
| 1 |
Ki = 213 nM
|
|
|
|
CP0397722
|
2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-N-(4-trifluoromethyl-phenyl)-acetamide
Show/Hide
|
C26H26F3N5O4
|
1
|
| 1 |
Ki = 213 nM
|
|
|
|
CP0440491
|
1-Benzyl-3-(4-methoxy-benzyl)-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C24H20N4O3
|
1
|
| 1 |
Ki = 213 nM
|
|
|
|
CP0453144
|
N-[4-(furan-2-yl)-11-(3-methylbutyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-naphthalen-1-ylacetamide
Show/Hide
|
C27H25N7O2
|
1
|
| 1 |
Ki = 215 nM
|
|
|
|
CP0515798
|
(2R,3R,4S,5R)-2-(7-amino-5-nitroimidazo[4,5-b]pyridin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C11H13N5O6
|
1
|
| 1 |
Ki = 216 nM
|
|
|
|
CP0894054
|
3-Ethoxycarbonyl-4,6-diethyl-5-ethylsulfanylcarbonyl-1-methyl-2-phenyl-pyridinium iodide
Show/Hide
|
C22H28INO3S
|
1
|
| 1 |
Ki = 219 nM
|
|
|
|
CP0449313
|
2-(3-Chloro-phenyl)-4,6-diethyl-5-hexylsulfanylcarbonyl-nicotinic acid propyl ester
Show/Hide
|
C26H34ClNO3S
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0490054
|
(2R,3R,4S,5R)-2-[6-(cyclopentylamino)-2-nitropurin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C15H20N6O6
|
1
|
| 1 |
Ki = 222 nM
|
|
|
|
CP0453281
|
(2,5-dioxopyrrolidin-1-yl) 2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetate
Show/Hide
|
C23H25N5O7
|
1
|
| 1 |
Ki = 227 nM
|
|
|
|
CP0448241
|
3-O-benzyl 5-O-ethyl 2-cyclohexyl-6-methyl-4-(2-phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C31H33NO4
|
1
|
| 1 |
Ki = 229 nM
|
|
|
|
CP0308003
|
N-(4-acetylphenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
Show/Hide
|
C27H29N5O5
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0443793
|
N-(2-pyridin-2-ylquinazolin-4-yl)benzamide
Show/Hide
|
C20H14N4O
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0432960
|
N-(4,6-diphenylpyrimidin-2-yl)acetamide
Show/Hide
|
C18H15N3O
|
1
|
| 1 |
Ki = 237 nM
|
|
|
|
CP0395159
|
N-(2-phenylquinazolin-4-yl)benzamide
Show/Hide
|
C21H15N3O
|
1
|
| 1 |
Ki = 240 nM
|
|
|
|
CP0429168
|
4-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-nicotinic acid ethyl ester
Show/Hide
|
C29H28N2O5S
|
1
|
| 1 |
Ki = 243 nM
|
|
|
|
CP0368224
|
8-cyclohexyl-6-(4-chlorophenyl)-2-phenyl-9H-purine
Show/Hide
|
C23H21ClN4
|
1
|
| 1 |
Ki = 243 nM
|
|
|
|
CP0374164
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2,2-dimethylpropanamide
Show/Hide
|
C18H16ClN5O2
|
1
|
| 1 |
Ki = 244 nM
|
|
|
|
CP0443785
|
8-Ethyl-1-oxo-6-phenyl-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carboxylic acid propyl ester
Show/Hide
|
C20H21NO3S
|
1
|
| 1 |
Ki = 248 nM
|
|
|
|
CP0858897
|
2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-methylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C16H25N7O3S
|
1
|
| 1 |
Ki = 253 nM
|
|
|
|
CP0878828
|
(2R,3R,4S,5S)-2-(6-amino-2-iodo-9H-purin-9-yl)-5-(methylthiomethyl)tetrahydrofuran-3,4-diol
Show/Hide
|
C11H14IN5O3S
|
1
|
| 1 |
Ki = 257 nM
|
|
|
|
CP0393717
|
9-Chloro-2-furan-2-yl-6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one
Show/Hide
|
C13H7ClN4O2
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0479887
|
6-Ethyl-5-ethylsulfanylcarbonyl-4-(2-hydroxy-ethyl)-2-phenyl-nicotinic acid propyl ester
Show/Hide
|
C22H27NO4S
|
1
|
| 1 |
Ki = 262 nM
|
|
|
|
CP0432961
|
N-(2,6-diphenylpyrimidin-4-yl)-2-methylpropanamide
Show/Hide
|
C20H19N3O
|
1
|
| 1 |
Ki = 267 nM
|
|
|
|
CP0503433
|
1-(1-Oxo-2-phenyl-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-3-phenyl-urea
Show/Hide
|
C22H16N6O2
|
1
|
| 1 |
Ki = 276 nM
|
|
|
|
CP0403028
|
N,N-dibenzyl-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
Show/Hide
|
C33H35N5O4
|
1
|
| 1 |
Ki = 284 nM
|
|
|
|
CP0853973
|
2-(6-Amino-2-iodo-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C10H12IN5O4
|
1
|
| 1 |
Ki = 297 nM
|
|
|
|
CP0069170
|
N-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-naphthalen-1-ylacetamide
Show/Hide
|
C31H25N7O2
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0397573
|
N-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenoxyacetamide
Show/Hide
|
C26H21N7O3
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0206176
|
2-Phenyl-3,5,7-tripropoxy-chromen-4-one
Show/Hide
|
C24H28O5
|
1
|
| 1 |
Ki = 317 nM
|
|
|
|
CP0372683
|
2-Hydroxymethyl-5-{6-(3-iodo-benzylamino)-2-[4-(4-methoxy-phenyl)-pyrazol-1-yl]-purin-9-yl}-tetrahydro-furan-3,4-diol
Show/Hide
|
C27H26IN7O5
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0435131
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-(2-chloroethyl)-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C12H15ClN6O4
|
1
|
| 1 |
Ki = 322 nM
|
|
|
|
CP0512418
|
4-Amino-2-(4-chloro-phenyl)-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C15H10ClN5O
|
1
|
| 1 |
Ki = 329 nM
|
|
|
|
CP0383165
|
1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2-yl]-3-ethyl-pent-1-yn-3-ol
Show/Hide
|
C19H20FN5O
|
1
|
| 1 |
Ki = 330 nM
|
|
|
|
CP0538303
|
(2R,3R,4S,5R)-2-[7-(cyclopentylamino)-5-nitroimidazo[4,5-b]pyridin-3-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C16H21N5O6
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0217073
|
7-Amino-heptanoic acid (9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-amide
Show/Hide
|
C20H21ClN6O2
|
1
|
| 1 |
Ki = 346 nM
|
|
|
|
CP0856372
|
2-(2-Benzyloxy-ethyl)-3-ethylsulfanylcarbonyl-1-methyl-6-phenyl-5-propoxycarbonyl-4-propyl-pyridinium iodide
Show/Hide
|
C31H38INO4S
|
1
|
| 1 |
Ki = 348 nM
|
|
|
|
CP0448990
|
N-(3-acetylphenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
Show/Hide
|
C27H29N5O5
|
1
|
| 1 |
Ki = 352 nM
|
|
|
|
CP0443759
|
4-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetylamino}-benzoic acid methyl ester
Show/Hide
|
C27H29N5O6
|
1
|
| 1 |
Ki = 363 nM
|
|
|
|
CP0546942
|
4-(2-methyl-3-phenylpyrazolo[3,4-d]pyridazin-7-yl)morpholine
Show/Hide
|
C16H17N5O
|
1
|
| 1 |
Ki = 363.08 nM
|
|
|
|
CP0080112
|
3,5,7-Triethoxy-2-phenyl-chromen-4-one
Show/Hide
|
C21H22O5
|
1
|
| 1 |
Ki = 364 nM
|
|
|
|
CP0943581
|
2,4-Diethyl-3-ethylsulfanylcarbonyl-5-(2-fluoro-ethoxycarbonyl)-1-methyl-6-phenyl-pyridinium iodide
Show/Hide
|
C22H27FINO3S
|
1
|
| 1 |
Ki = 364 nM
|
|
|
|
CP0499506
|
1-Benzyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C16H12N4O2
|
1
|
| 1 |
Ki = 370 nM
|
|
|
|
CP0942104
|
3-Ethoxycarbonyl-4-ethyl-5-ethylsulfanylcarbonyl-1,6-dimethyl-2-phenyl-pyridinium iodide
Show/Hide
|
C21H26INO3S
|
1
|
| 1 |
Ki = 379 nM
|
|
|
|
CP0575929
|
N-benzyl-1-methyl-3-propan-2-ylpyrazolo[3,4-d]pyridazin-7-amine
Show/Hide
|
C16H19N5
|
1
|
| 1 |
Ki = 380.19 nM
|
|
|
|
CP0437765
|
2-Amino-4-benzo[1,3]dioxol-5-yl-6-furan-2-yl-nicotinonitrile
Show/Hide
|
C17H11N3O3
|
1
|
| 1 |
Ki = 390 nM
|
|
|
|
CP0109688
|
2-(4-(2,4-dioxo-1,3-dipropyl-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy)-N-(4-fluorophenyl)acetamide
Show/Hide
|
C25H26FN5O4
|
1
|
| 1 |
Ki = 391 nM
|
|
|
|
CP0432963
|
N-(2,6-diphenylpyrimidin-4-yl)pentanamide
Show/Hide
|
C21H21N3O
|
1
|
| 1 |
Ki = 392 nM
|
|
|
|
CP0869547
|
2-(6-Amino-2-iodo-purin-9-yl)-5-ethylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C12H16IN5O3S
|
1
|
| 1 |
Ki = 395 nM
|
|
|
|
CP0083160
|
2-(4-fluorophenoxy)-N-(7-methoxy-4-morpholin-4-yl-[1,3]thiazolo[5,4-c]pyridin-2-yl)-2-methylpropanamide
Show/Hide
|
C21H23FN4O4S
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0383270
|
(1R,2R,3S,4R,5S)-4-(6-Amino-purin-9-yl)-1-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C12H15N5O3
|
1
|
| 1 |
Ki = 404 nM
|
|
|
|
CP0847469
|
2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-isopropylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H29N7O3S
|
1
|
| 1 |
Ki = 409 nM
|
|
|
|
CP0468117
|
N-(3-phenyl-1,2,4-thiadiazol-5-yl)benzamide
Show/Hide
|
C15H11N3OS
|
1
|
| 1 |
Ki = 410 nM
|
|
|
|
CP0899648
|
(R)-2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-((R)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl) ester 5-ethyl ester
Show/Hide
|
C30H31NO6
|
1
|
| 1 |
Ki = 426 nM
|
|
|
|
CP0845729
|
2-Butyl-5-ethoxycarbonyl-4-ethyl-3-ethylsulfanylcarbonyl-1-methyl-6-phenyl-pyridinium iodide
Show/Hide
|
C24H32INO3S
|
1
|
| 1 |
Ki = 436 nM
|
|
|
|
CP0476881
|
2-(4-amino-6-phenyl-1,3,5-triazin-2-yl)phenol
Show/Hide
|
C15H12N4O
|
1
|
| 1 |
Ki = 440 nM
|
|
|
|
CP0496382
|
6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid 2,2,3,3,3-pentafluoro-propyl ester
Show/Hide
|
C23H24F5NO3S
|
1
|
| 1 |
Ki = 446 nM
|
|
|
|
CP0461821
|
N-(2,6-diphenylpyrimidin-4-yl)-3-methylbutanamide
Show/Hide
|
C21H21N3O
|
1
|
| 1 |
Ki = 447 nM
|
|
|
|
CP0882938
|
2-Ethyl-3-(3-fluoro-propylsulfanylcarbonyl)-1-methyl-6-phenyl-5-propoxycarbonyl-4-propyl-pyridinium iodide
Show/Hide
|
C25H33FINO3S
|
1
|
| 1 |
Ki = 465 nM
|
|
|
|
CP0051345
|
(1R,2R,3S,4R,5S)-4-(2-Chloro-6-cyclopentylamino-purin-9-yl)-1-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C17H22ClN5O3
|
1
|
| 1 |
Ki = 466 nM
|
|
|
|
CP0512422
|
2-Phenyl-5-prop-2-ynyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C18H12N4O2
|
1
|
| 1 |
Ki = 479 nM
|
|
|
|
CP0941728
|
2,4-Diethyl-3-ethylsulfanylcarbonyl-1-methyl-6-phenyl-5-propoxycarbonyl-pyridinium iodide
Show/Hide
|
C23H30INO3S
|
1
|
| 1 |
Ki = 483 nM
|
|
|
|
CP0330093
|
2-(3,4-difluorophenoxy)-N-(4-methoxy-7-morpholin-4-yl-1,3-benzothiazol-2-yl)-2-methylpropanamide
Show/Hide
|
C22H23F2N3O4S
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0430531
|
5-Methyl-2-p-tolyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C17H14N4O2
|
1
|
| 1 |
Ki = 504 nM
|
|
|
|
CP0510067
|
4-(cyclohexylamino)-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one
Show/Hide
|
C21H21N5O
|
1
|
| 1 |
Ki = 506 nM
|
|
|
|
CP0453493
|
6-Ethyl-2-phenyl-4-propyl-5-[2-(tetrahydro-pyran-2-yloxy)-ethylsulfanylcarbonyl]-nicotinic acid propyl ester
Show/Hide
|
C28H37NO5S
|
1
|
| 1 |
Ki = 517 nM
|
|
|
|
CP0853676
|
2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C27H27NO6
|
1
|
| 1 |
Ki = 520 nM
|
|
|
|
CP0378361
|
4-Chloro-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide
Show/Hide
|
C15H10ClN3OS
|
1
|
| 1 |
Ki = 520 nM
|
|
|
|
CP0942122
|
4-(2-Acetylsulfanyl-ethyl)-2-ethyl-3-ethylsulfanylcarbonyl-1-methyl-6-phenyl-5-propoxycarbonyl-pyridinium iodide
Show/Hide
|
C25H32INO4S2
|
1
|
| 1 |
Ki = 538 nM
|
|
|
|
CP0106488
|
2-Amino-4-(4-hydroxy-phenyl)-6-(1H-imidazol-2-ylmethylsulfanyl)-pyridine-3,5-dicarbonitrile
Show/Hide
|
C17H12N6OS
|
1
|
| 1 |
Ki = 538 nM
|
|
|
|
CP0497001
|
1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2-ylethynyl]-cyclohexanol
Show/Hide
|
C20H20FN5O
|
1
|
| 1 |
Ki = 540 nM
|
|
|
|
CP0847368
|
2-(6-Amino-2-iodo-purin-9-yl)-5-isopropylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C13H18IN5O3S
|
1
|
| 1 |
Ki = 546 nM
|
|
|
|
CP0395863
|
N-(4,6-diphenylpyrimidin-2-yl)propanamide
Show/Hide
|
C19H17N3O
|
1
|
| 1 |
Ki = 547 nM
|
|
|
|
CP0425093
|
4-(cyclohexylamino)-2-m-tolyl-[1,2,4]triazolo[4,3-a]quinoxalin-1(2H)-one
Show/Hide
|
C22H23N5O
|
1
|
| 1 |
Ki = 548 nM
|
|
|
|
CP0047889
|
(2R,3R,4S,5R)-2-(6-(benzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C17H19N5O4
|
1
|
| 1 |
Ki = 550 nM
|
|
|
|
CP0421140
|
1-Benzyl-7-tert-butyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
Ki = 555 nM
|
|
|
|
CP0853472
|
2-(6-Amino-2-iodo-purin-9-yl)-5-propylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C13H18IN5O3S
|
1
|
| 1 |
Ki = 558 nM
|
|
|
|
CP0375209
|
3,6-Dichloro-2-(2-isobutoxy-4-methyl-phenyl)-chromen-4-one
Show/Hide
|
C20H18Cl2O3
|
1
|
| 1 |
Ki = 561 nM
|
|
|
|
CP0847738
|
5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carbothioic acid ethylamide
Show/Hide
|
C12H16N6O3S
|
1
|
| 1 |
Ki = 569 nM
|
|
|
|
CP0069838
|
(4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl ester
Show/Hide
|
C26H26N6O4
|
1
|
| 1 |
Ki = 570 nM
|
|
|
|
CP0892628
|
3-Ethoxycarbonyl-1,4,6-triethyl-5-ethylsulfanylcarbonyl-2-phenyl-pyridinium iodide
Show/Hide
|
C23H30INO3S
|
1
|
| 1 |
Ki = 577 nM
|
|
|
|
CP0501349
|
4-Methoxy-3-methyl-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide
Show/Hide
|
C17H15N3O2S
|
1
|
| 1 |
Ki = 580 nM
|
|
|
|
CP0222480
|
2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C13H13N7O
|
1
|
| 1 |
Ki = 613 nM
|
|
|
|
CP0433704
|
N-[6-(1,3-benzodioxol-5-yl)-2-phenylpyrimidin-4-yl]-2-ethylbutanamide
Show/Hide
|
C23H23N3O3
|
1
|
| 1 |
Ki = 634 nM
|
|
|
|
CP0870839
|
7-Ethyl-4-methyl-2-styryl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one
Show/Hide
|
C18H19N5O
|
1
|
| 1 |
Ki = 640 nM
|
|
|
|
CP0885743
|
2-(6-Benzylamino-purin-9-yl)-5-propylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H25N5O3S
|
1
|
| 1 |
Ki = 647 nM
|
|
|
|
CP0918277
|
2-Methyl-6-phenyl-4-styryl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C27H27NO6
|
1
|
| 1 |
Ki = 650 nM
|
|
|
|
CP0866817
|
2-(4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7yl)propyl)phenoxy)-N-(5-aminopentyl)acetamide
Show/Hide
|
C26H31N9O3
|
1
|
| 1 |
Ki = 656 nM
|
|
|
|
CP0491710
|
1-Phenyl-2-(3-pyridin-2-yl-isoquinolin-1-yl)-ethanone
Show/Hide
|
C22H16N2O
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0271478
|
5-O-ethyl 3-O-methyl 2,6-dimethyl-4-[(E)-2-phenylethenyl]-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C20H23NO4
|
1
|
| 1 |
Ki = 670 nM
|
|
|
|
CP0377525
|
N-(3,4-dimethyl-2,5-dioxopyrrol-1-yl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
Show/Hide
|
C25H28N6O6
|
1
|
| 1 |
Ki = 670 nM
|
|
|
|
CP0043633
|
4-Methoxy-N-(4-phenyl-thiazol-2-yl)-benzamide
Show/Hide
|
C17H14N2O2S
|
1
|
| 1 |
Ki = 670 nM
|
|
|
|
CP0432962
|
N-(4,6-diphenylpyrimidin-2-yl)cyclopropanecarboxamide
Show/Hide
|
C20H17N3O
|
1
|
| 1 |
Ki = 676 nM
|
|
|
|
CP0858074
|
2-Cyclopentyl-3-ethoxycarbonyl-4,6-diethyl-5-ethylsulfanylcarbonyl-1-methyl-pyridinium iodide
Show/Hide
|
C21H32INO3S
|
1
|
| 1 |
Ki = 695 nM
|
|
|
|
CP0916473
|
2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-propylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H29N7O3S
|
1
|
| 1 |
Ki = 697 nM
|
|
|
|
CP0917467
|
5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid (3,3,3-trifluoro-propyl)-amide
Show/Hide
|
C13H15F3N6O4
|
1
|
| 1 |
Ki = 719 nM
|
|
|
|
CP0430859
|
N'-(3-pyridin-2-ylisoquinolin-1-yl)benzenecarboximidamide
Show/Hide
|
C21H16N4
|
1
|
| 1 |
Ki = 730 nM
|
|
|
|
CP0081090
|
3,6-Dichloro-2-phenyl-chromen-4-one
Show/Hide
|
C15H8Cl2O2
|
1
|
| 1 |
Ki = 741 nM
|
|
|
|
CP0299735
|
3,7-Diethoxy-5-hydroxy-2-phenyl-chromen-4-one
Show/Hide
|
C19H18O5
|
1
|
| 1 |
Ki = 748 nM
|
|
|
|
CP0856106
|
(R)-2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester
Show/Hide
|
C31H27NO4
|
1
|
| 1 |
Ki = 750 nM
|
|
|
|
CP0015755
|
9-Methyl-2-pentyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine
Show/Hide
|
C13H18N8
|
1
|
| 1 |
Ki = 760 nM
|
|
|
|
CP0542862
|
4-Methoxy-N-(6-phenyl-pyrimidin-4-yl)-benzamide
Show/Hide
|
C18H15N3O2
|
1
|
| 1 |
Ki = 800 nM
|
|
|
|
CP0847369
|
2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-ethylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C17H27N7O3S
|
1
|
| 1 |
Ki = 814 nM
|
|
|
|
CP0448382
|
2-[4-[2,6-dioxo-1,3-bis(prop-2-enyl)-7H-purin-8-yl]phenoxy]acetic acid
Show/Hide
|
C19H18N4O5
|
1
|
| 1 |
Ki = 816 nM
|
|
|
|
CP0407269
|
N-[2-(5-bromofuran-2-yl)-9-chloro-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]benzamide
Show/Hide
|
C20H11BrClN5O2
|
1
|
| 1 |
Ki = 856 nM
|
|
|
|
CP0182221
|
3-Amino-N-(9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-propionamide
Show/Hide
|
C16H13ClN6O2
|
1
|
| 1 |
Ki = 874 nM
|
|
|
|
CP0061180
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2-(3-iodophenyl)acetamide
Show/Hide
|
C21H13ClIN5O2
|
1
|
| 1 |
Ki = 882 nM
|
|
|
|
CP0471937
|
(E)-N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-3-phenylprop-2-enamide
Show/Hide
|
C19H20N6O5
|
1
|
| 1 |
Ki = 900 nM
|
|
|
|
CP0894597
|
3-[4-(1,3-Bis-cyclohexylmethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl]-acrylic acid
Show/Hide
|
C28H34N4O4
|
1
|
| 1 |
Ki = 922 nM
|
|
|
|
CP0201127
|
5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(2-phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C20H21NO4
|
1
|
| 1 |
Ki = 940 nM
|
|
|
|
CP0406245
|
1-Benzyl-7-tert-butyl-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
Ki = 950 nM
|
|
|
|
CP0380418
|
1-(4-Methoxy-phenyl)-3-(1-oxo-2-phenyl-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-urea
Show/Hide
|
C23H18N6O3
|
1
|
| 1 |
Ki = 960 nM
|
|
|
|
CP0496305
|
(2S,3S,4R,5R)-5-[6-Amino-2-(3-cyclopentyl-propionylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide
Show/Hide
|
C20H29N7O5
|
1
|
| 1 |
Ki = 1010 nM
|
|
|
|
CP0464144
|
4-(2,2-Diphenyl-ethylamino)-2-phenyl-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C29H23N5O
|
1
|
| 1 |
Ki = 1020 nM
|
|
|
|
CP0448945
|
N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-3-cyclopentylpropanamide
Show/Hide
|
C18H26N6O5
|
1
|
| 1 |
Ki = 1040 nM
|
|
|
|
CP0429360
|
N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-4-cyclohexylbutanamide
Show/Hide
|
C20H30N6O5
|
1
|
| 1 |
Ki = 1060 nM
|
|
|
|
CP0374780
|
4-Iodo-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide
Show/Hide
|
C15H10IN3OS
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0377249
|
1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2-ylethynyl]-cyclopentanol
Show/Hide
|
C19H18FN5O
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0421036
|
4-(1-Benzyl-2,4-dioxo-1,4-dihydro-2H-1,3,4b,9-tetraaza-fluoren-3-yl)-but-2-enoic acid methyl ester
Show/Hide
|
C21H18N4O4
|
1
|
| 1 |
Ki = 1125 nM
|
|
|
|
CP0357363
|
(2R)-2-amino-N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]propanamide
Show/Hide
|
C16H13ClN6O2
|
1
|
| 1 |
Ki = 1140 nM
|
|
|
|
CP0162577
|
4-Ethoxy-7-((E)-styryl)-furo[3,2-g]chromen-5-one
Show/Hide
|
C21H16O4
|
1
|
| 1 |
Ki = 1160 nM
|
|
|
|
CP0405723
|
N-(2,6-diphenylpyrimidin-4-yl)-4-methoxybenzamide
Show/Hide
|
C24H19N3O2
|
1
|
| 1 |
Ki = 1170 nM
|
|
|
|
CP0257420
|
(2S)-2-amino-N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]propanamide
Show/Hide
|
C16H13ClN6O2
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0448218
|
2-[4-[(3-phenyl-1,2,4-thiadiazol-5-yl)carbamoyl]phenoxy]acetic acid
Show/Hide
|
C17H13N3O4S
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0521145
|
N-(3-phenylisoquinolin-1-yl)benzamide
Show/Hide
|
C22H16N2O
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0042738
|
3,5,7-Trimethoxy-2-phenyl-chromen-4-one
Show/Hide
|
C18H16O5
|
1
|
| 1 |
Ki = 1210 nM
|
|
|
|
CP0504146
|
N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-2-cyclohexylacetamide
Show/Hide
|
C18H26N6O5
|
1
|
| 1 |
Ki = 1230 nM
|
|
|
|
CP0573093
|
2-Phenyl-5-propyl-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione
Show/Hide
|
C18H16N4O2
|
1
|
| 1 |
Ki = 1246 nM
|
|
|
|
CP0884297
|
4-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-3-ethoxycarbonyl-6-ethyl-5-ethylsulfanylcarbonyl-1-methyl-2-phenyl-pyridinium iodide
Show/Hide
|
C30H31IN2O5S
|
1
|
| 1 |
Ki = 1250 nM
|
|
|
|
CP0441634
|
N-[6-(cyclopentylamino)-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-3-phenylpropanamide
Show/Hide
|
C24H30N6O5
|
1
|
| 1 |
Ki = 1250 nM
|
|
|
|
CP0057624
|
2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)-N-(4-iodophenyl)acetamide
Show/Hide
|
C25H26IN5O4
|
1
|
| 1 |
Ki = 1270 nM
|
|
|
|
CP0399699
|
(2S,3S,4R,5R)-2-(chloromethyl)-5-[6-(cyclopentylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C15H20ClN5O3
|
1
|
| 1 |
Ki = 1290 nM
|
|
|
|
CP0293834
|
8-Cyclopentyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C12H16N4O2
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0458807
|
N-(2,6-diphenylpyrimidin-4-yl)benzamide
Show/Hide
|
C23H17N3O
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0920630
|
(S)-2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-((R)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl) ester 5-ethyl ester
Show/Hide
|
C30H31NO6
|
1
|
| 1 |
Ki = 1310 nM
|
|
|
|
CP0944981
|
3-Ethoxycarbonyl-4,6-diethyl-5-ethylsulfanylcarbonyl-2-phenyl-1-propyl-pyridinium iodide
Show/Hide
|
C24H32INO3S
|
1
|
| 1 |
Ki = 1350 nM
|
|
|
|
CP0186712
|
2-(3,4-Dihydroxy-phenyl)-3-hydroxy-7-methoxy-chromen-4-one
Show/Hide
|
C16H12O6
|
1
|
| 1 |
Ki = 1380 nM
|
|
|
|
CP0916297
|
2-Cyclobutyl-5-ethoxycarbonyl-4-ethyl-3-ethylsulfanylcarbonyl-1-methyl-6-phenyl-pyridinium iodide
Show/Hide
|
C24H30INO3S
|
1
|
| 1 |
Ki = 1410 nM
|
|
|
|
CP0494164
|
3-Cyclopentyl-N-[6-cyclopentylamino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-yl]-propionamide
Show/Hide
|
C23H34N6O5
|
1
|
| 1 |
Ki = 1410 nM
|
|
|
|
CP0886421
|
4-(2,2-Diphenyl-vinyl)-2-methyl-6-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C32H31NO4
|
1
|
| 1 |
Ki = 1420 nM
|
|
|
|
CP0546925
|
N-benzyl-2-methyl-3-propan-2-ylpyrazolo[3,4-d]pyridazin-7-amine
Show/Hide
|
C16H19N5
|
1
|
| 1 |
Ki = 1698.24 nM
|
|
|
|
CP0510880
|
4-Benzylamino-2-phenyl-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C22H17N5O
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0919017
|
7-Ethyl-1,4-dimethyl-2-styryl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one
Show/Hide
|
C19H21N5O
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0058033
|
1,3-dipropyl-8-cyclopentylxanthine
Show/Hide
|
C16H24N4O2
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0145442
|
5,4'-Dihydroxy-6,7-dimethoxyflavone
Show/Hide
|
C17H14O6
|
1
|
| 1 |
Ki = 1720 nM
|
|
|
|
CP0461092
|
4-Methoxy-N-(4-pyridin-2-yl-thiazol-2-yl)-benzamide
Show/Hide
|
C16H13N3O2S
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0402571
|
9-Chloro-2-furan-2-yl-6-propyl-6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one
Show/Hide
|
C16H13ClN4O2
|
1
|
| 1 |
Ki = 1813 nM
|
|
|
|
CP0910323
|
2-(6-Benzylamino-purin-9-yl)-5-chloromethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C17H18ClN5O3
|
1
|
| 1 |
Ki = 1860 nM
|
|
|
|
CP0520148
|
(1S,2R,3S,4R,5S)-4-(1,3-Dibutyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)-2,3-dihydroxy-bicyclo[3.1.0]hexane-1-carboxylic acid methylamide
Show/Hide
|
C21H31N5O5
|
1
|
| 1 |
Ki = 1860 nM
|
|
|
|
CP0273477
|
N-(4-chlorophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
Show/Hide
|
C25H26ClN5O4
|
1
|
| 1 |
Ki = 1870 nM
|
|
|
|
CP0654265
|
Dexniguldipine
Show/Hide
|
C36H39N3O6
|
1
|
| 1 |
Ki = 1900 nM
|
|
|
|
CP0058124
|
3-Hydroxymethyl-5-[6-(3-iodo-benzylamino)-purin-9-yl]-cyclopentane-1,2-diol
Show/Hide
|
C18H20IN5O3
|
1
|
| 1 |
Ki = 1960 nM
|
|
|
|
CP0429169
|
1-Ethyl-9-oxo-3-phenyl-6,7,8,9-tetrahydro-5H-pyrido[3,4-c]azepine-4-carboxylic acid ethyl ester
Show/Hide
|
C20H22N2O3
|
1
|
| 1 |
Ki = 1990 nM
|
|
|
|
CP0855037
|
2-Ethyl-3-ethylsulfanylcarbonyl-1-methyl-6-phenyl-5-propoxycarbonyl-4-propyl-pyridinium iodide
Show/Hide
|
C24H32INO3S
|
1
|
| 1 |
Ki = 2020 nM
|
|
|
|
CP0903161
|
2-(4-(3-(5-Amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7yl)propyl)phenoxy)-N-(6-aminohexyl)acetamide
Show/Hide
|
C27H33N9O3
|
1
|
| 1 |
Ki = 2070 nM
|
|
|
|
CP0460452
|
N-(4-pyridin-2-yl-1,3-thiazol-2-yl)cyclopentanecarboxamide
Show/Hide
|
C14H15N3OS
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0377242
|
4-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2-yl]-2-methyl-but-3-yn-2-ol
Show/Hide
|
C17H16FN5O
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0907056
|
2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-propyl ester
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 2110 nM
|
|
|
|
CP0866827
|
2-(4-(3-(5-Amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7yl)propyl)phenoxy)-N-(3-aminopropyl)acetamide
Show/Hide
|
C24H27N9O3
|
1
|
| 1 |
Ki = 2170 nM
|
|
|
|
CP0264364
|
diethyl 4-ethyl-2-methyl-6-phenyl-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 2270 nM
|
|
|
|
CP0907773
|
5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carbothioic acid cyclopropylamide
Show/Hide
|
C13H16N6O3S
|
1
|
| 1 |
Ki = 2280 nM
|
|
|
|
CP0944437
|
2,6-Dimethyl-4-phenethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0161793
|
N-(4-bromophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
Show/Hide
|
C25H26BrN5O4
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0433188
|
2-Cyclobutyl-6-methyl-4-phenylethynyl-pyridine-3,5-dicarboxylic acid 3-benzyl ester 5-ethyl ester
Show/Hide
|
C29H27NO4
|
1
|
| 1 |
Ki = 2410 nM
|
|
|
|
CP0448758
|
3,4-Dichloro-N-(4-pyridin-2-yl-thiazol-2-yl)-benzamide
Show/Hide
|
C15H9Cl2N3OS
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0466523
|
8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C22H28N4O4
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0052752
|
diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C19H22N2O6
|
1
|
| 1 |
Ki = 2510 nM
|
|
|
|
CP0453736
|
5-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethylsulfanylcarbonyl)-6-ethyl-2-phenyl-4-propyl-nicotinic acid propyl ester
Show/Hide
|
C27H35NO5S
|
1
|
| 1 |
Ki = 2640 nM
|
|
|
|
CP0055377
|
2-(2,4-Dimethoxy-phenyl)-3,5,7-trimethoxy-chromen-4-one
Show/Hide
|
C20H20O7
|
1
|
| 1 |
Ki = 2650 nM
|
|
|
|
CP0851744
|
4-((4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)phenoxy)methyl)benzenesulfonic acid, ammonia salt
Show/Hide
|
C26H26N8O5S
|
1
|
| 1 |
Ki = 2660 nM
|
|
|
|
CP0116393
|
2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C19H17N7O
|
1
|
| 1 |
Ki = 2666 nM
|
|
|
|
CP0405780
|
N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-3-phenylpropanamide
Show/Hide
|
C19H22N6O5
|
1
|
| 1 |
Ki = 2710 nM
|
|
|
|
CP0398623
|
N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]cyclohexanecarboxamide
Show/Hide
|
C17H24N6O5
|
1
|
| 1 |
Ki = 2760 nM
|
|
|
|
CP0648338
|
2,6-Dimethyl-5-nitro-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid methyl ester
Show/Hide
|
C16H15F3N2O4
|
1
|
| 1 |
Ki = 2770 nM
|
|
|
|
CP0925882
|
2,4,6-Trimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-benzyl ester 5-methyl ester
Show/Hide
|
C18H21NO4
|
1
|
| 1 |
Ki = 2780 nM
|
|
|
|
CP0087323
|
Niguldipine
Show/Hide
|
C36H39N3O6
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0383229
|
2-Methyl-6-phenyl-4-((E)-styryl)-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C26H25NO4
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0496493
|
4-Iodo-N-(4-pyridin-2-yl-thiazol-2-yl)-benzamide
Show/Hide
|
C15H10IN3OS
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0168163
|
(E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(2-phenyl-pyrazolo[1,5-a]pyridin-3-yl)-propenone
Show/Hide
|
C23H25N3O2
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0885862
|
2-Ethyl-4-methyl-6-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 2830 nM
|
|
|
|
CP0499511
|
1-Methyl-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C13H14N4O2
|
1
|
| 1 |
Ki = 3020 nM
|
|
|
|
CP0022329
|
3,5,7-Trihydroxyflavone
Show/Hide
|
C15H10O5
|
1
|
| 1 |
Ki = 3150 nM
|
|
|
|
CP0395257
|
4-Chloro-N-(4-pyridin-2-yl-thiazol-2-yl)-benzamide
Show/Hide
|
C15H10ClN3OS
|
1
|
| 1 |
Ki = 3200 nM
|
|
|
|
CP0410677
|
4-Methyl-N-(4-pyridin-2-yl-thiazol-2-yl)-benzamide
Show/Hide
|
C16H13N3OS
|
1
|
| 1 |
Ki = 3200 nM
|
|
|
|
CP0055461
|
CHEBI:7550
Show/Hide
|
C26H29N3O6
|
1
|
| 1 |
Ki = 3250 nM
|
|
|
|
CP0405722
|
4-chloro-N-(4,6-diphenylpyrimidin-2-yl)benzamide
Show/Hide
|
C23H16ClN3O
|
1
|
| 1 |
Ki = 3280 nM
|
|
|
|
CP0463157
|
1-(4-Methoxy-phenyl)-3-(3-phenyl-[1,2,4]thiadiazol-5-yl)-urea
Show/Hide
|
C16H14N4O2S
|
1
|
| 1 |
Ki = 3300 nM
|
|
|
|
CP0453086
|
1,4-Dimethyl-2-phenyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one
Show/Hide
|
C15H15N5O
|
1
|
| 1 |
Ki = 3330 nM
|
|
|
|
CP0171259
|
3,5,7-Trimethoxy-2-(4-methoxy-phenyl)-chromen-4-one
Show/Hide
|
C19H18O6
|
1
|
| 1 |
Ki = 3370 nM
|
|
|
|
CP0147544
|
5,4'-Dihydroxy-7-o-methoxyflavanone
Show/Hide
|
C16H14O5
|
1
|
| 1 |
Ki = 3400 nM
|
|
|
|
CP0133321
|
N-(4-pyridin-2-yl-1,3-thiazol-2-yl)benzamide
Show/Hide
|
C15H11N3OS
|
1
|
| 1 |
Ki = 3400 nM
|
|
|
|
CP0465410
|
4-Nitro-N-(4-pyridin-2-yl-thiazol-2-yl)-benzamide
Show/Hide
|
C15H10N4O3S
|
1
|
| 1 |
Ki = 3500 nM
|
|
|
|
CP0258378
|
8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
|
C12H11N7O
|
1
|
| 1 |
Ki = 3579 nM
|
|
|
|
CP0530046
|
4-Isopropoxy-N-(4-pyridin-2-yl-thiazol-2-yl)-benzamide
Show/Hide
|
C18H17N3O2S
|
1
|
| 1 |
Ki = 3700 nM
|
|
|
|
CP0373039
|
2-Cyclopentyl-6-methyl-4-phenylethynyl-pyridine-3,5-dicarboxylic acid 3-benzyl ester 5-ethyl ester
Show/Hide
|
C30H29NO4
|
1
|
| 1 |
Ki = 3850 nM
|
|
|
|
CP0057629
|
2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetic acid
Show/Hide
|
C19H22N4O5
|
1
|
| 1 |
Ki = 3910 nM
|
|
|
|
CP0099739
|
4-Propoxy-7-((E)-styryl)-furo[3,2-g]chromen-5-one
Show/Hide
|
C22H18O4
|
1
|
| 1 |
Ki = 3950 nM
|
|
|
|
CP0534887
|
1-Phenyl-3-(3-phenyl-[1,2,4]thiadiazol-5-yl)-urea
Show/Hide
|
C15H12N4OS
|
1
|
| 1 |
Ki = 4000 nM
|
|
|
|
CP0946027
|
4-(4-Methoxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Show/Hide
|
C19H23NO5
|
1
|
| 1 |
Ki = 4100 nM
|
|
|
|
CP0493353
|
1,3-Dibutyl-7-((1S,2R,3S,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-bicyclo[3.1.0]hex-2-yl)-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C20H30N4O5
|
1
|
| 1 |
Ki = 4350 nM
|
|
|
|
CP0386543
|
3-noradamantyl-1,3-dipropylxanthine
Show/Hide
|
C20H28N4O2
|
1
|
| 1 |
Ki = 4390 nM
|
|
|
|
CP0449387
|
2,4-Dimethyl-6-phenyl-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C19H21NO4
|
1
|
| 1 |
Ki = 4470 nM
|
|
|
|
CP0504869
|
5,6,7-Trimethyl-2-p-tolyl-chromen-4-one
Show/Hide
|
C19H18O2
|
1
|
| 1 |
Ki = 4480 nM
|
|
|
|
CP0869436
|
4-Benzo[1,3]dioxol-5-yl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Show/Hide
|
C19H21NO6
|
1
|
| 1 |
Ki = 4580 nM
|
|
|
|
CP0812277
|
2-(2,4-Dihydroxy-phenyl)-5-hydroxy-7-methoxy-6-((E)-3-methyl-but-1-enyl)-3-(3-methyl-but-2-enyl)-chromen-4-one
Show/Hide
|
C26H28O6
|
1
|
| 1 |
Ki = 4590 nM
|
|
|
|
CP0448196
|
3-Chloro-N-(4-pyridin-2-yl-thiazol-2-yl)-benzamide
Show/Hide
|
C15H10ClN3OS
|
1
|
| 1 |
Ki = 4600 nM
|
|
|
|
CP0428069
|
1,3-dipropyl-8-[2-(5,6-exo-epoxy-(1S,2S)-norborn-2-yl)]-xanthine
Show/Hide
|
C18H24N4O3
|
1
|
| 1 |
Ki = 4810 nM
|
|
|
|
CP0056016
|
2-(2,4-Diethoxy-phenyl)-3,7-diethoxy-5-hydroxy-chromen-4-one
Show/Hide
|
C23H26O7
|
1
|
| 1 |
Ki = 4830 nM
|
|
|
|
CP0448856
|
1-Phenyl-3-(4-pyridin-2-yl-thiazol-2-yl)-urea
Show/Hide
|
C15H12N4OS
|
1
|
| 1 |
Ki = 5000 nM
|
|
|
|
CP0234129
|
A2A
Show/Hide
|
C19H26N4O4S
|
1
|
| 1 |
Ki = 5000 nM
|
|
|
|
CP0323463
|
2-(4-fluorophenoxy)-N-(4-methoxy-7-morpholin-4-yl-1,3-benzothiazol-2-yl)-2-methylpropanamide
Show/Hide
|
C22H24FN3O4S
|
1
|
| 1 |
Ki = 5000 nM
|
|
|
|
CP0471806
|
3,6-Dichloro-2-(2,4,6-trimethyl-phenyl)-chromen-4-one
Show/Hide
|
C18H14Cl2O2
|
1
|
| 1 |
Ki = 5240 nM
|
|
|
|
CP0724391
|
2,4,6-Trimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(2-phenylsulfanyl-ethyl) ester
Show/Hide
|
C20H25NO4S
|
1
|
| 1 |
Ki = 5560 nM
|
|
|
|
CP0886781
|
2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Show/Hide
|
C18H20N2O6
|
1
|
| 1 |
Ki = 5900 nM
|
|
|
|
CP0905099
|
2-(4-(3-(5-Amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7yl)propyl)phenoxy)-N-(4-aminobutyl)acetamide
Show/Hide
|
C25H29N9O3
|
1
|
| 1 |
Ki = 5990 nM
|
|
|
|
CP0042218
|
2'-Hydroxyflavanone
Show/Hide
|
C15H12O3
|
1
|
| 1 |
Ki = 6070 nM
|
|
|
|
CP0920619
|
2,6-Dimethyl-4-propyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Show/Hide
|
C15H23NO4
|
1
|
| 1 |
Ki = 6510 nM
|
|
|
|
CP0081164
|
5-Hydroxy-2-(4-methoxy-phenyl)-7-methyl-chromen-4-one
Show/Hide
|
C17H14O4
|
1
|
| 1 |
Ki = 6700 nM
|
|
|
|
CP0441857
|
CHEMBL424908
Show/Hide
|
C23H33N5O5
|
1
|
| 1 |
Ki = 6700 nM
|
|
|
|
CP0653550
|
2,4-Dimethyl-6-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C19H23NO4
|
1
|
| 1 |
Ki = 7240 nM
|
|
|
|
CP0192841
|
2-(2,4-Diethoxy-phenyl)-3,5,7-triethoxy-chromen-4-one
Show/Hide
|
C25H30O7
|
1
|
| 1 |
Ki = 7270 nM
|
|
|
|
CP0892060
|
4-(2,6-Dimethyl-hept-5-enyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Show/Hide
|
C21H33NO4
|
1
|
| 1 |
Ki = 7900 nM
|
|
|
|
CP0056658
|
4-Methoxy-7-((E)-styryl)-furo[3,2-g]chromen-5-one
Show/Hide
|
C20H14O4
|
1
|
| 1 |
Ki = 8280 nM
|
|
|
|
CP0046619
|
Adalat
Show/Hide
|
C17H18N2O6
|
1
|
| 1 |
Ki = 8290 nM
|
|
|
|
CP0072374
|
BAY-E-5009
Show/Hide
|
C18H20N2O6
|
1
|
| 1 |
Ki = 8300 nM
|
|
|
|
CP0015320
|
BAY-E-9736
Show/Hide
|
C21H26N2O7
|
1
|
| 1 |
Ki = 8470 nM
|
|
|
|
CP0437806
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-tert-butyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C14H20N6O4
|
1
|
| 1 |
Ki = 8500 nM
|
|
|
|
CP0451324
|
4-Methoxy-N-(6-phenyl-pyridin-2-yl)-benzamide
Show/Hide
|
C19H16N2O2
|
1
|
| 1 |
Ki = 8700 nM
|
|
|
|
CP0859369
|
2-Methyl-4-((E)-styryl)-6-p-tolyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C27H29NO4
|
1
|
| 1 |
Ki = 9130 nM
|
|
|
|
CP0258199
|
4-Methoxy-7-[(E)-phenyliminomethyl]-furo[3,2-g]chromen-5-one
Show/Hide
|
C19H13NO4
|
1
|
| 1 |
Ki = 9180 nM
|
|
|
|
CP0404399
|
1-Phenyl-3-(4-phenyl-thiazol-2-yl)-urea
Show/Hide
|
C16H13N3OS
|
1
|
| 1 |
Ki = 9900 nM
|
|
|
|
CP0216911
|
N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2-(2-iodophenyl)acetamide
Show/Hide
|
C21H13ClIN5O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0054097
|
2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C18H15N7O
|
2
|
| 1 |
Ki > 10000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0393327
|
2-(furan-2-yl)-7-(3-phenylpropyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C19H17N7O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0403353
|
4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)phenol
Show/Hide
|
C19H17N7O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0405161
|
7-(4-Benzyloxy-benzyl)-2-furan-2-yl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
|
C24H19N7O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0405188
|
7-(3-(benzo[d][1,3]dioxol-5-yl)propyl)-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C20H17N7O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0419179
|
7-(3-(3,4-dimethoxyphenyl)propyl)-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C21H21N7O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0424440
|
4-[2-(5-Amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-ethyl]-phenol
Show/Hide
|
C18H15N7O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0429950
|
4-(5-Amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-ylmethyl)-phenol
Show/Hide
|
C17H13N7O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0441968
|
7-[2-(4-Benzyloxy-phenyl)-ethyl]-2-furan-2-yl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
|
C25H21N7O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0505359
|
7-[3-(4-Benzyloxy-phenyl)-propyl]-2-furan-2-yl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
|
C26H23N7O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0559504
|
4-[3-(5-Amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-propyl]-benzene-1,2-diol
Show/Hide
|
C19H17N7O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0377961
|
4-methoxy-N-(3-phenylphenyl)benzamide
Show/Hide
|
C20H17NO2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0428185
|
3-{[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-bicyclo[2.2.2]octane-1-carbonyl]-amino}-propionic acid methy lester
Show/Hide
|
C24H35N5O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0499917
|
3-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-bicyclo[2.2.2]oct-1-yl]-propionic acid
Show/Hide
|
C22H32N4O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0488532
|
8-(5-oxo-4-oxatricyclo[4.2.1.03,7]nonan-9-yl)-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C19H24N4O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0415983
|
3-ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4-dione
Show/Hide
|
C18H22F3N3O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0545475
|
4-(1-methyl-3-phenylpyrazolo[3,4-d]pyridazin-7-yl)morpholine
Show/Hide
|
C16H17N5O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0569089
|
N-benzyl-2-methyl-3-phenylpyrazolo[3,4-d]pyridazin-7-amine
Show/Hide
|
C19H17N5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0503348
|
(R)-Phosphoric acid mono-[(S)-(1S,3R,6R)-2,3-dihydroxy-4-(6-hydroxy-purin-9-yl)-bicyclo[3.1.0]hex-1-ylmethyl] ester
Show/Hide
|
C12H15N4O7P
|
1
|
| 1 |
Ki = 11000 nM
|
|
|
|
CP0045955
|
3-Chloro-2-phenyl-chromen-4-one
Show/Hide
|
C15H9ClO2
|
1
|
| 1 |
Ki = 11500 nM
|
|
|
|
CP0927010
|
2,6-Dimethyl-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Show/Hide
|
C19H20F3NO4
|
1
|
| 1 |
Ki = 11600 nM
|
|
|
|
CP0496969
|
5-O-ethyl 3-O-methyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate
Show/Hide
|
C18H21NO4
|
1
|
| 1 |
Ki = 12000 nM
|
|
|
|
CP0448323
|
3-Methylsulfanyl-6,7-dihydro-benzo[c]thiophene-1-carboxylic acid hydrazide
Show/Hide
|
C10H12N2OS2
|
1
|
| 1 |
Ki = 13000 nM
|
|
|
|
CP0043620
|
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Show/Hide
|
C8H10N4O2
|
1
|
| 1 |
Ki = 13300 nM
|
|
|
|
CP0724409
|
4-Ethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Show/Hide
|
C14H21NO4
|
1
|
| 1 |
Ki = 13600 nM
|
|
|
|
CP0403805
|
N-(3-phenyl-1,2,4-thiadiazol-5-yl)cyclohexanecarboxamide
Show/Hide
|
C15H17N3OS
|
1
|
| 1 |
Ki = 16000 nM
|
|
|
|
CP0245886
|
3,5,7-Trimethoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one
Show/Hide
|
C21H22O8
|
1
|
| 1 |
Ki = 16200 nM
|
|
|
|
CP0081624
|
2-phenylchromen-4-one
Show/Hide
|
C15H10O2
|
1
|
| 1 |
Ki = 16900 nM
|
|
|
|
CP0039135
|
Acetic acid 5,7-diacetoxy-4-oxo-2-phenyl-4H-chromen-3-yl ester
Show/Hide
|
C21H16O8
|
1
|
| 1 |
Ki = 17500 nM
|
|
|
|
CP0465005
|
2-[{6-[Bis-(2-hydroxy-ethyl)-amino]-4,8-di-piperidin-1-yl-1,4-dihydro-pyrimido[5,4-d]pyrimidin-2-yl}-(2-hydroxy-ethyl)-amino]-ethanol
Show/Hide
|
C24H42N8O4
|
1
|
| 1 |
Ki = 19000 nM
|
|
|
|
CP0449888
|
(2R,4S)-4-(2-Amino-6-hydroxy-purin-9-yl)-1-((R)-(R)-1-hydroxymethyl)-bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C12H15N5O4
|
1
|
| 1 |
Ki = 20500 nM
|
|
|
|
CP0727407
|
3-Hydroxy-6-methoxy-2-((E)-styryl)-chroman-4-one
Show/Hide
|
C18H16O4
|
1
|
| 1 |
Ki = 21100 nM
|
|
|
|
CP0526742
|
[[(1R,2R,3S,4R,5S)-2,3-dihydroxy-4-(6-oxo-1H-purin-9-yl)-1-bicyclo[3.1.0]hexanyl]methoxy-hydroxyphosphoryl] [(1R,2R,3S,4R,5S)-2,3-dihydroxy-4-(6-oxo-1H-purin-9-yl)-1-bicyclo[3.1.0]hexanyl]methyl hydrogen phosphate
Show/Hide
|
C24H28N8O13P2
|
1
|
| 1 |
Ki = 21600 nM
|
|
|
|
CP0535302
|
1,2,3,4-Tetrahydro-carbazol-4a-ol
Show/Hide
|
C12H13NO
|
1
|
| 1 |
Ki = 22000 nM
|
|
|
|
CP0379373
|
Acetic acid (3Z,9E)-16-benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylene-18-oxo-17-aza-tricyclo[9.7.0.0*1,15*]octadeca-3,9-dien-2-yl ester
Show/Hide
|
C30H39NO5
|
1
|
| 1 |
Ki = 23000 nM
|
|
|
|
CP0653739
|
SID124879353
Show/Hide
|
C16H15F3N2O4
|
1
|
| 1 |
Ki = 23500 nM
|
|
|
|
CP0407035
|
1-(2-Pyridin-3-yl-quinazolin-4-yl)-3-o-tolyl-urea
Show/Hide
|
C21H17N5O
|
1
|
| 1 |
Ki = 23900 nM
|
|
|
|
CP0112143
|
5-(piperazine-1-sulfonyl)isoquinoline
Show/Hide
|
C13H15N3O2S
|
1
|
| 1 |
Ki = 25000 nM
|
|
|
|
CP0507007
|
2-{4-[(2-Amino-4-oxo-1,4-dihydro-pteridin-6-ylamino)-methyl]-benzoylamino}-pentanedioic acid
Show/Hide
|
C19H19N7O6
|
1
|
| 1 |
Ki = 28000 nM
|
|
|
|
CP0453110
|
1-(2-Methoxy-phenyl)-3-(2-pyridin-2-yl-quinazolin-4-yl)-urea
Show/Hide
|
C21H17N5O2
|
1
|
| 1 |
Ki = 28200 nM
|
|
|
|
CP0374273
|
(1S,2R,6S)-2,3-Dihydroxy-4-(6-hydroxy-purin-9-yl)-bicyclo[3.1.0]hexane-1-carboxylic acid (S,R)-methylamide
Show/Hide
|
C13H15N5O4
|
1
|
| 1 |
Ki = 28800 nM
|
|
|
|
CP0020849
|
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
Show/Hide
|
C15H10O7
|
1
|
| 1 |
Ki = 30000 nM
|
|
|
|
CP0518508
|
(1S,2R,3R,6R)-1-((S)-Hydroxymethyl)-4-(6-hydroxy-purin-9-yl)-bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C12H14N4O4
|
1
|
| 1 |
Ki = 30000 nM
|
|
|
|
CP0858084
|
7-Ethyl-1,4-dimethyl-2-styryl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one
Show/Hide
|
C19H21N5O
|
1
|
| 1 |
Ki = 30600 nM
|
|
|
|
CP0340419
|
6-Chloro-2-phenyl-chromen-4-one
Show/Hide
|
C15H9ClO2
|
1
|
| 1 |
Ki = 32000 nM
|
|
|
|
CP0920565
|
4-(4-Hydroxy-3-methoxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Show/Hide
|
C19H23NO6
|
1
|
| 1 |
Ki = 32100 nM
|
|
|
|
CP0040161
|
2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopyran-4-one
Show/Hide
|
C15H10O7
|
1
|
| 1 |
Ki = 34000 nM
|
|
|
|
CP0068119
|
cmdc.202100576, 15
Show/Hide
|
C15H12O7
|
1
|
| 1 |
Ki = 34100 nM
|
|
|
|
CP0530044
|
4-Hydroxy-3-methylsulfanyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid ethyl ester
Show/Hide
|
C12H16O3S2
|
1
|
| 1 |
Ki = 35800 nM
|
|
|
|
CP0041792
|
2,3-Dihydro-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Show/Hide
|
C15H12O3
|
1
|
| 1 |
Ki = 42800 nM
|
|
|
|
CP0162579
|
4-Ethoxy-7-((1E,3E)-4-phenyl-buta-1,3-dienyl)-furo[3,2-g]chromen-5-one
Show/Hide
|
C23H18O4
|
1
|
| 1 |
Ki = 45500 nM
|
|
|
|
CP0879815
|
2-Butyl-4,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
Show/Hide
|
C17H27NO4
|
1
|
| 1 |
Ki = 47100 nM
|
|
|
|
CP0381043
|
pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C8H6N2O
|
1
|
| 1 |
Ki = 48000 nM
|
|
|
|
CP0080649
|
3-Hydroxy-2-(2,4,6-trimethoxy-phenyl)-chromen-4-one
Show/Hide
|
C18H16O6
|
1
|
| 1 |
Ki = 50100 nM
|
|
|
|
CP0122605
|
2,3-Dihydroflavone
Show/Hide
|
C15H12O2
|
1
|
| 1 |
Ki = 50100 nM
|
|
|
|
CP0503654
|
1-Phenyl-3-(2-pyridin-3-yl-quinazolin-4-yl)-urea
Show/Hide
|
C20H15N5O
|
1
|
| 1 |
Ki = 50900 nM
|
|
|
|
CP0064158
|
4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one
Show/Hide
|
C13H10O4
|
1
|
| 1 |
Ki = 60000 nM
|
|
|
|
CP0921976
|
2,4,6-Trimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-methoxy-ethyl) ester 5-methyl ester
Show/Hide
|
C14H21NO5
|
1
|
| 1 |
Ki = 62300 nM
|
|
|
|
CP0845658
|
1-(6-Amino-purin-9-yl)-4-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol
Show/Hide
|
C12H15N5O3
|
1
|
| 1 |
Ki = 62500 nM
|
|
|
|
CP0422258
|
1-Phenyl-3-(2-pyrrolidin-1-yl-quinazolin-4-yl)-urea
Show/Hide
|
C19H19N5O
|
1
|
| 1 |
Ki = 82300 nM
|
|
|
|
CP0042654
|
1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Show/Hide
|
C7H8N4O2
|
1
|
| 1 |
Ki = 86000 nM
|
|
|
|
CP0554903
|
1-(2-Methoxy-phenyl)-3-(2-phenyl-quinazolin-4-yl)-urea
Show/Hide
|
C22H18N4O2
|
1
|
| 1 |
Ki = 87300 nM
|
|
|
|
CP0257983
|
4-Methoxy-5-oxo-5H-furo[3,2-g]chromene-7-carbaldehyde
Show/Hide
|
C13H8O5
|
1
|
| 1 |
Ki = 88900 nM
|
|
|
|
CP0202130
|
(2R,3R,4S,5R)-2-{6-Amino-2-[4-(4-methoxy-phenyl)-pyrazol-1-yl]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H21N7O5
|
1
|
| 1 |
Ki > 6 nM
|
|
|
|
CP0054092
|
1-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-yl]-1H-pyrazole-4-carboxylic acid methylamide
Show/Hide
|
C15H18N8O5
|
1
|
| 1 |
Ki > 10 nM
|
|
|
|
CP0076042
|
(2R,3R,4S,5R)-2-[6-Amino-2-(1-benzyl-1H-pyrazol-4-yl)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H21N7O4
|
1
|
| 1 |
Ki > 10 nM
|
|
|
|
CP0028721
|
2-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine
Show/Hide
|
C12H16N8
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0395301
|
4-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetylamino}-benzamide
Show/Hide
|
C26H28N6O5
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0404077
|
4-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetylamino}-benzoic acid (0.60CH2CL2)
Show/Hide
|
C26H27N5O6
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0916219
|
4-(4-Methoxy-phenyl)-1,4-dihydro-pyridine
Show/Hide
|
C12H13NO
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
