Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-benzyl-1-methyl-3-phenylpyrazolo[3,4-d]pyridazin-7-amine
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 PubChem ID
CID: 168289948
Canonical SMILES
Cn1nc(-c2ccccc2)c2cnnc(NCc3ccccc3)c12
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Compound Formula C19H17N5
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A3
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Nucleotide-like receptor (family A GPCR)
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Adenosine receptor
Uniprot ID
P0DMS8
Gene Name
ADORA3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000386 Flp-In-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 15.85 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Kd = 54.95 nM
   TI
   LI
   LO
   TS
2
Ki = 12.88 nM
   TI
   LI
   LO
   TS