Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
    Show/Hide
 PubChem ID
CID: 11014188
SID: 16075819
Canonical SMILES
Cn1cc2c(n1)nc(NC(=O)Cc1ccccc1)n1nc(nc21)-c1ccco1
    Show/Hide
Compound Formula C19H15N7O2
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P0DMS8
Gene Name
ADORA3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 6.4 nM
   TI
   LI
   LO
   TS
2
Ki = 0.81 nM
   TI
   LI
   LO
   TS
3
Ki = 812.83 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.81 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.8091 nM
2 Ki = 0.81 nM