Brief Information of the Compound and Protein
Compound Name
N-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
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PubChem ID
CID: 11014188
SID: 16075819
Canonical SMILES
Cn1cc2c(n1)nc(NC(=O)Cc1ccccc1)n1nc(nc21)-c1ccco1
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Compound Formula C19H15N7O2
Compound Structure
Protein Name
Adenosine receptor A3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Nucleotide-like receptor (family A GPCR)
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Adenosine receptor
Uniprot ID
P0DMS8
Gene Name
ADORA3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
IC50 = 6.4 nM
   TI
   LI
   LO
   TS
2
Ki = 0.81 nM
   TI
   LI
   LO
   TS
3
Ki = 812.83 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 0.81 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.8091 nM
2 Ki = 0.81 nM