General Information of the Compound
Compound ID
CP0399729
Compound Name
4-(5-Butyl-[1,2,4]triazolo[1,5-c]quinazolin-2-yl)-phenol
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Structure
Formula
C19H18N4O
Molecular Weight
318.38
Canonical SMILES
CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(O)cc1
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InChI
InChI=1S/C19H18N4O/c1-2-3-8-17-20-16-7-5-4-6-15(16)19-21-18(22-23(17)19)13-9-11-14(24)12-10-13/h4-7,9-12,24H,2-3,8H2,1H3
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InChIKey
LNTJHSDODUWPHB-UHFFFAOYSA-N
Physicochemical Property
logP
3.9927
Rotatable Bonds
4
Heavy Atom Count
24
Polar Areas
63.31
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 135738656
ChEMBL ID
CHEMBL338057
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 5300 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS