Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-anilino-N-(5-anilino-1H-pyrazolo[3,4-c]pyridin-3-yl)acetamide
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 PubChem ID
CID: 168291120
Canonical SMILES
O=C(CNc1ccccc1)Nc1n[nH]c2cnc(Nc3ccccc3)cc12
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Compound Formula C20H18N6O
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Nucleotide-like receptor (family A GPCR)
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Adenosine receptor
Uniprot ID
P0DMS8
Gene Name
ADORA3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000386 Flp-In-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 3.02 nM
   TI
   LI
   LO
   TS
2
Kd = 489.78 nM
   TI
   LI
   LO
   TS
3
Ki = 0.1148 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Kd = 354.81 nM
   TI
   LI
   LO
   TS