Brief Information of the Cell Line and Protein
Cell Line ID: CL000013 , Sf9
Synonyms
SF9
sf9
SF-9
Sf-9
sf-9
Sf 9
Spodoptera frugiperda clone 9
Sf clone 9
IPLB-Sf-9AE
IPLB-SF-9AE
IPLB-SF-9
IPLB-Sf-9
IPLB-Sf9
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0549
Protein ID: PT03652 , Mitogen-activated protein kinase kinase kinase 14
Gene Name MAP3K14
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q99558
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000013  Protein ID: PT03652
 
Compound ID Compound Name Compound Formula
CP0231830
4-[1-(2-amino-5-chloropyrimidin-4-yl)-2,3-dihydroindol-6-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H16ClN5OS
 1
1
IC50 = 3.981 nM
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CP0533534
3-[2-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-fluorophenyl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
   Show/Hide
C19H16FN5O2
 1
1
IC50 = 5.9 nM
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   LI
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   TS
CP0459477
(2R)-4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H14FN5OS
 1
1
IC50 = 9.1 nM
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CP0390947
6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-4-methoxypyridine-2-carboxamide
   Show/Hide
C20H19N3O4
 1
1
IC50 = 10 nM
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   TS
CP0536766
(2R)-4-[1-(2-amino-5-chloropyrimidin-4-yl)-2,3-dihydroindol-6-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H16ClN5OS
 1
1
IC50 = 15.1 nM
   TI
   LI
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   TS
CP0533530
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C18H14N6OS
 1
1
IC50 = 22.4 nM
   TI
   LI
   LO
   TS
CP0472095
3-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpiperidin-2-one
   Show/Hide
C19H18N6O2
 1
1
IC50 = 25.7 nM
   TI
   LI
   LO
   TS
CP0459476
3-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
   Show/Hide
C18H16N6O2
 1
1
IC50 = 26.1 nM
   TI
   LI
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   TS
CP0184914
4-[3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl]-2-methylbut-3-yn-2-ol
   Show/Hide
C20H22N4O3
 2
1
IC50 = 39.81 nM
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2
IC50 = 70 nM
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   TS
CP0564419
3-[2-[4-(2-amino-4-methylpyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
   Show/Hide
C19H18N6O2
 1
1
IC50 = 85.2 nM
   TI
   LI
   LO
   TS
CP0536712
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H14FN5OS
 1
1
IC50 = 85.5 nM
   TI
   LI
   LO
   TS
CP0521573
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-fluoropyridin-2-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C18H13FN6OS
 1
1
IC50 = 87.3 nM
   TI
   LI
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   TS
CP0548749
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-2-(5-methyl-1,2-oxazol-3-yl)but-3-yn-2-ol
   Show/Hide
C19H16N6O2
 1
1
IC50 = 120 nM
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   LI
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   TS
CP0548751
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-methoxyphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C20H17N5O2S
 1
1
IC50 = 120 nM
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CP0550872
3-[2-[4-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
   Show/Hide
C20H20N6O2
 1
1
IC50 = 189.8 nM
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CP0579800
4-[6-[2-(4-ethynylpyrimidin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C19H11N7
 1
1
IC50 = 199.53 nM
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   LI
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   TS
CP0416712
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H14FN5OS
 1
1
IC50 = 204 nM
   TI
   LI
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   TS
CP0543831
4-[3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H14FN5OS
 1
1
IC50 = 215 nM
   TI
   LI
   LO
   TS
CP0467967
4-[3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-methoxyphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C20H17N5O2S
 1
1
IC50 = 216 nM
   TI
   LI
   LO
   TS
CP0548750
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H15N5OS
 1
1
IC50 = 218 nM
   TI
   LI
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   TS
CP0533528
4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-[3-hydroxy-3-(1,3-thiazol-2-yl)but-1-ynyl]benzonitrile
   Show/Hide
C20H14N6OS
 1
1
IC50 = 219 nM
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CP0564418
1-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]cyclopentan-1-ol
   Show/Hide
C18H17N5O
 1
1
IC50 = 234 nM
   TI
   LI
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CP0547303
4-(6-ethynylbenzimidazol-1-yl)pyrimidin-2-amine
   Show/Hide
C13H9N5
 1
1
IC50 = 251.19 nM
   TI
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   TS
CP0533533
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-methoxyphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C20H17N5O2S
 1
1
IC50 = 290 nM
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   LI
   LO
   TS
CP0540938
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-(5-methyl-1,2-oxazol-3-yl)but-3-yn-2-ol
   Show/Hide
C20H17N5O2
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0557770
4-[3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H15N5OS
 1
1
IC50 = 303 nM
   TI
   LI
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   TS
CP0577157
4-[6-[2-(4-ethynylpyridin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C20H12N6
 1
1
IC50 = 316.23 nM
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   TS
CP0536711
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H14FN5OS
 1
1
IC50 = 319 nM
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CP0438033
4-[3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-methylphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C20H17N5OS
 1
1
IC50 = 335 nM
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   TS
CP0521571
1-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]cyclobutan-1-ol
   Show/Hide
C17H15N5O
 1
1
IC50 = 388 nM
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CP0536767
3-[2-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
   Show/Hide
C19H17N5O2
 1
1
IC50 = 410 nM
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CP0564420
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-pyrazin-2-ylbut-3-yn-2-ol
   Show/Hide
C20H16N6O
 1
1
IC50 = 468 nM
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   TS
CP0416715
1-[2-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]ethynyl]cyclopentan-1-ol
   Show/Hide
C19H18N4O
 1
1
IC50 = 475 nM
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CP0562749
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2,4-difluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H13F2N5OS
 1
1
IC50 = 641 nM
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CP0426706
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-methylbut-3-yn-2-ol
   Show/Hide
C17H16N4O
 1
1
IC50 = 720 nM
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CP0473924
1-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]cycloheptan-1-ol
   Show/Hide
C20H21N5O
 1
1
IC50 = 748 nM
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CP0521572
1-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]cyclohexan-1-ol
   Show/Hide
C19H19N5O
 1
1
IC50 = 1570 nM
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CP0575802
4-[6-[2-(4-methylpyrimidin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C18H13N7
 1
1
IC50 = 1584.89 nM
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CP0576331
4-[6-[2-(4-ethenylpyridin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C20H14N6
 1
1
IC50 = 1584.89 nM
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CP0578521
4-[6-[2-(4-ethenylpyrimidin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C19H13N7
 1
1
IC50 = 1584.89 nM
   TI
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CP0543833
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-2-pyrazin-2-ylbut-3-yn-2-ol
   Show/Hide
C19H15N7O
 1
1
IC50 = 1640 nM
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CP0548747
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C20H17N5O2S
 1
1
IC50 = 1750 nM
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   TS
CP0426705
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C18H14N6OS
 1
1
IC50 = 1860 nM
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CP0479843
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-cyclohexylbut-3-yn-2-ol
   Show/Hide
C22H24N4O
 1
1
IC50 = 2030 nM
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CP0438034
3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[3-hydroxy-3-(1,3-thiazol-2-yl)but-1-ynyl]benzonitrile
   Show/Hide
C20H14N6OS
 1
1
IC50 = 2060 nM
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CP0533529
4-[3-(2-amino-5-chloropyrrolo[2,3-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H14ClN5OS
 1
1
IC50 = 2061 nM
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CP0459478
4-[3-(2-amino-6-methyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C20H17N5OS
 1
1
IC50 = 2204 nM
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CP0438036
(2S)-4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H14FN5OS
 1
1
IC50 = 2230 nM
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CP0564411
1-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-3-(1,3-thiazol-2-yl)pent-1-yn-3-ol
   Show/Hide
C19H16N6OS
 1
1
IC50 = 2290 nM
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CP0004106
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
   Show/Hide
C28H26N4O3
 1
1
IC50 = 2300 nM
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CP0533532
3-[2-[4-(6-aminopyrrolo[2,3-b]pyridin-1-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
   Show/Hide
C19H17N5O2
 1
1
IC50 = 2481 nM
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CP0543832
4-[3-(2-amino-4-methoxypyrrolo[2,3-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C20H17N5O2S
 1
1
IC50 = 2484 nM
   TI
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   TS
CP0905360
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclobutyl)methanone
   Show/Hide
C15H15Cl2N3O
 1
1
IC50 = 2900 nM
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   TS
CP0580187
4-[6-[2-(6-ethynylpyridin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C20H12N6
 1
1
IC50 = 3162.28 nM
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CP0864827
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclohexyl)methanone
   Show/Hide
C17H19Cl2N3O
 1
1
IC50 = 3300 nM
   TI
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   TS
CP0472094
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H15N5OS
 1
1
IC50 = 3837 nM
   TI
   LI
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   TS
CP0533531
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-2-hydroxy-2-methyl-1-pyrrolidin-1-ylbut-3-yn-1-one
   Show/Hide
C20H20N6O2
 1
1
IC50 = 6160 nM
   TI
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   TS
CP0568060
4-[6-[2-(6-ethynylpyrazin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C19H11N7
 1
1
IC50 = 6309.57 nM
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CP0580186
N-[3-[3-(2-aminopyrimidin-4-yl)benzimidazol-5-yl]prop-2-ynyl]prop-2-enamide
   Show/Hide
C17H14N6O
 1
1
IC50 = 6309.57 nM
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CP0530513
3-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-1-(1,3-thiazol-2-yl)prop-2-yn-1-ol
   Show/Hide
C18H13N5OS
 1
1
IC50 = 6380 nM
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CP0639989
1-(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)ethan-1-one
   Show/Hide
C12H11Cl2N3O
 1
1
IC50 = 8400 nM
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   TS
CP0416713
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-(6-methoxypyridin-2-yl)but-3-yn-2-ol
   Show/Hide
C22H19N5O2
 1
1
IC50 > 10000 nM
   TI
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   TS
CP0426704
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-[2-(dimethylamino)ethoxy]phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C23H24N6O2S
 1
1
IC50 > 10000 nM
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   TS
CP0426707
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-hydroxy-N,N,2-trimethylbut-3-ynamide
   Show/Hide
C19H19N5O2
 1
1
IC50 > 10000 nM
   TI
   LI
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   TS
CP0438350
4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-[3-hydroxy-3-(1,3-thiazol-2-yl)but-1-ynyl]-N,N-dimethylbenzamide
   Show/Hide
C22H20N6O2S
 1
1
IC50 > 10000 nM
   TI
   LI
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   TS
CP0438351
4-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]piperidin-4-ol
   Show/Hide
C18H18N6O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0536714
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-hydroxy-2-methyl-1-pyrrolidin-1-ylbut-3-yn-1-one
   Show/Hide
C21H21N5O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0542925
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-chlorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H14ClN5OS
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0554011
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-(methylamino)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C20H18N6OS
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0530512
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-2-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C19H14FN5OS
 1
1
IC50 = 10910 nM
   TI
   LI
   LO
   TS
CP0548748
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-methylphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C20H17N5OS
 1
1
IC50 = 11700 nM
   TI
   LI
   LO
   TS
CP0864828
1-(3-amino-4-bromo-5-methyl-1H-pyrazol-1-yl)ethan-1-one
   Show/Hide
C6H8BrN3O
 1
1
IC50 = 12500 nM
   TI
   LI
   LO
   TS
CP0579782
4-[6-[2-(2-ethenylpyridin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C20H14N6
 1
1
IC50 = 19952.62 nM
   TI
   LI
   LO
   TS
CP0915203
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(phenyl)methanone
   Show/Hide
C17H13Cl2N3O
 1
1
IC50 = 23000 nM
   TI
   LI
   LO
   TS
CP0876658
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclopropyl)methanone
   Show/Hide
C14H13Cl2N3O
 1
1
IC50 = 24300 nM
   TI
   LI
   LO
   TS
CP0574431
4-[6-[2-(5-ethynylpyrimidin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C19H11N7
 1
1
IC50 = 25118.86 nM
   TI
   LI
   LO
   TS
CP0426703
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-(2-methoxyethoxy)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
   Show/Hide
C22H21N5O3S
 1
1
IC50 = 25830 nM
   TI
   LI
   LO
   TS
CP0905359
1-(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)propan-1-one
   Show/Hide
C13H13Cl2N3O
 1
1
IC50 = 27400 nM
   TI
   LI
   LO
   TS
CP0579783
4-[6-[2-(2-ethynylpyridin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C20H12N6
 1
1
IC50 = 31622.78 nM
   TI
   LI
   LO
   TS
CP0911844
1-(5-amino-4-(3,4-dimethylphenyl)-3-methyl-1H-pyrazol-1-yl)ethan-1-one
   Show/Hide
C14H17N3O
 1
1
IC50 = 39600 nM
   TI
   LI
   LO
   TS
CP0579469
4-[6-[2-(2-ethenylpyrimidin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C19H13N7
 1
1
IC50 = 39810.72 nM
   TI
   LI
   LO
   TS
CP0580188
4-[6-[2-(2-ethynylpyrimidin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C19H11N7
 1
1
IC50 = 39810.72 nM
   TI
   LI
   LO
   TS
CP0893469
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclopentyl)methanone
   Show/Hide
C16H17Cl2N3O
 1
1
IC50 = 41000 nM
   TI
   LI
   LO
   TS
CP0500658
4-(ethoxymethylene)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
C12H11NO3
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0576333
4-[6-[2-(6-ethynylpyrimidin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C19H11N7
 1
1
IC50 = 50118.72 nM
   TI
   LI
   LO
   TS
CP0307611
4H-isoquinoline-1,3-dione
   Show/Hide
C9H7NO2
 1
1
IC50 = 51000 nM
   TI
   LI
   LO
   TS
CP0893471
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(pyridin-4-yl)methanone
   Show/Hide
C16H12Cl2N4O
 1
1
IC50 = 58200 nM
   TI
   LI
   LO
   TS
CP0869606
SID24808657
   Show/Hide
C10H10ClN3
 1
1
IC50 = 61100 nM
   TI
   LI
   LO
   TS
CP0576332
4-[6-[2-(5-ethynylpyridin-3-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C20H12N6
 1
1
IC50 = 63095.73 nM
   TI
   LI
   LO
   TS
CP0547305
4-[6-[2-(6-ethenylpyridin-3-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C20H14N6
 1
1
IC50 = 79432.82 nM
   TI
   LI
   LO
   TS
CP0571379
4-(6-ethylbenzimidazol-1-yl)pyrimidin-2-amine
   Show/Hide
C13H13N5
 1
1
IC50 = 79432.82 nM
   TI
   LI
   LO
   TS
CP0575603
4-[6-[2-(2-ethynylpyrimidin-5-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
   Show/Hide
C19H11N7
 1
1
IC50 = 79432.82 nM
   TI
   LI
   LO
   TS
CP0400398
2,7-naphthyridine-1,3,6,8-tetrone
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C8H8N2O4
 1
1
IC50 = 90000 nM
   TI
   LI
   LO
   TS
CP0058616
5-Hydroxy-2-methyl-[1,4]naphthoquinone
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C11H8O3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0398575
5,7-dichloroquinazoline-2,4(1H,3H)-dione
   Show/Hide
C8H4Cl2N2O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0500659
4-(thiophen-2-ylmethylene)isoquinoline-1,3(2H,4H)-dione
   Show/Hide
C14H9NO2S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0535128
1,2-dihydroisoquinolin-3(4H)-one
   Show/Hide
C9H9NO
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0357240
5-methyl-4-phenyl-1H-pyrazol-3-amine
   Show/Hide
C10H11N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0852538
1-(3-amino-4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-1-yl)ethan-1-one
   Show/Hide
C12H11Cl2N3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0852539
4-(3,4-dichlorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine
   Show/Hide
C11H11Cl2N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0852540
N-(4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-yl)-2,2,2-trifluoroacetamide
   Show/Hide
C12H8Cl2F3N3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0852541
4-(4-bromophenyl)-5-methyl-1H-pyrazol-3-amine
   Show/Hide
C10H10BrN3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0852542
N-(5-chloro-9H-pyrido[3,4-b]indol-7-yl)nicotinamide
   Show/Hide
C17H11ClN4O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0852543
1-(5-amino-4-(3,4-dichlorophenyl)-3-ethyl-1H-pyrazol-1-yl)ethan-1-one
   Show/Hide
C13H13Cl2N3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0852545
4-(benzo[d][1,3]dioxol-5-yl)-5-methyl-1H-pyrazol-3-amine
   Show/Hide
C11H11N3O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0852546
5-methyl-4-p-tolyl-1H-pyrazol-3-amine
   Show/Hide
C11H13N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0852547
1-(5-amino-3-methyl-4-(3-(trifluoromethyl)phenyl)-1H-pyrazol-1-yl)ethan-1-one
   Show/Hide
C13H12F3N3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0864824
1-(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)butan-1-one
   Show/Hide
C14H15Cl2N3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0864825
(5-amino-4-(4-chlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclopropyl)methanone
   Show/Hide
C14H14ClN3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0864826
5-methyl-4-(naphthalen-2-yl)-1H-pyrazol-3-amine
   Show/Hide
C14H13N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0864830
N-[4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-yl]pyridine-2-carboxamide
   Show/Hide
C16H12Cl2N4O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0864831
1-(5-amino-4-(4-chlorophenyl)-3-methyl-1H-pyrazol-1-yl)ethan-1-one
   Show/Hide
C12H12ClN3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0876657
4-(3,4-dichlorophenyl)-1,5-dimethyl-1H-pyrazol-3-amine
   Show/Hide
C11H11Cl2N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0876659
5-methyl-4-(3-methylphenyl)-1H-pyrazol-3-amine
   Show/Hide
C11H13N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0876660
1-(5-amino-4-bromo-3-methyl-1H-pyrazol-1-yl)ethan-1-one
   Show/Hide
C6H8BrN3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0880318
4-(3-chlorophenyl)-5-methyl-1H-pyrazol-3-amine
   Show/Hide
C10H10ClN3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0880319
5-methyl-4-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
   Show/Hide
C11H10F3N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0893470
(3-amino-4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-1-yl)(cyclobutyl)methanone
   Show/Hide
C15H15Cl2N3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0893477
tert-butyl 5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazole-1-carboxylate
   Show/Hide
C15H17Cl2N3O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0893478
5-amino-4-(3,4-dichlorophenyl)-N-ethyl-3-methyl-1H-pyrazole-1-carboxamide
   Show/Hide
C13H14Cl2N4O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0893479
4-(3-bromophenyl)-5-methyl-1H-pyrazol-3-amine
   Show/Hide
C10H10BrN3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0893480
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(pyridin-3-yl)methanone
   Show/Hide
C16H12Cl2N4O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0905361
(3-amino-4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-1-yl)(pyridin-3-yl)methanone
   Show/Hide
C16H12Cl2N4O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0905362
5-methyl-4-(3-(trifluoromethoxy)phenyl)-1H-pyrazol-3-amine
   Show/Hide
C11H10F3N3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0905363
4-(4-(benzyloxy)phenyl)-5-methyl-1H-pyrazol-3-amine
   Show/Hide
C17H17N3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0911845
1-(5-amino-4-(3-chlorophenyl)-3-methyl-1H-pyrazol-1-yl)ethan-1-one
   Show/Hide
C12H12ClN3O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0915202
4-(3,5-bis(trifluoromethyl)phenyl)-5-methyl-1H-pyrazol-3-amine
   Show/Hide
C12H9F6N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0915204
4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-amine
   Show/Hide
C10H9Cl2N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0915205
5-(3,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-amine
   Show/Hide
C10H9Cl2N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0945628
4-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3-amine
   Show/Hide
C12H15N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0580166
N-[3-[3-(2-aminopyrimidin-4-yl)benzimidazol-5-yl]propyl]acetamide
   Show/Hide
C16H18N6O
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0382724
3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)-N-[2-[2-[2-[2-[[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]propanamide
   Show/Hide
C49H54BF2N7O7
 1
1
Kd = 352 nM
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   TS
CP0382649
3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)-N-[2-[2-[2-[2-[[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-methylamino]ethoxy]ethoxy]ethoxy]ethyl]propanamide
   Show/Hide
C50H56BF2N7O7
 1
1
Kd = 445 nM
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   TS