Compound ID |
Compound Name |
Compound Formula |
CP0231830
|
4-[1-(2-amino-5-chloropyrimidin-4-yl)-2,3-dihydroindol-6-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H16ClN5OS
|
1
|
1 |
IC50 = 3.981 nM
|
|
|
CP0533534
|
3-[2-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-fluorophenyl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
Show/Hide
|
C19H16FN5O2
|
1
|
1 |
IC50 = 5.9 nM
|
|
|
CP0459477
|
(2R)-4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H14FN5OS
|
1
|
1 |
IC50 = 9.1 nM
|
|
|
CP0390947
|
6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl]phenyl]-4-methoxypyridine-2-carboxamide
Show/Hide
|
C20H19N3O4
|
1
|
1 |
IC50 = 10 nM
|
|
|
CP0536766
|
(2R)-4-[1-(2-amino-5-chloropyrimidin-4-yl)-2,3-dihydroindol-6-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H16ClN5OS
|
1
|
1 |
IC50 = 15.1 nM
|
|
|
CP0533530
|
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C18H14N6OS
|
1
|
1 |
IC50 = 22.4 nM
|
|
|
CP0472095
|
3-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpiperidin-2-one
Show/Hide
|
C19H18N6O2
|
1
|
1 |
IC50 = 25.7 nM
|
|
|
CP0459476
|
3-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
Show/Hide
|
C18H16N6O2
|
1
|
1 |
IC50 = 26.1 nM
|
|
|
CP0184914
|
4-[3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C20H22N4O3
|
2
|
1 |
IC50 = 39.81 nM
|
|
|
2 |
IC50 = 70 nM
|
|
|
CP0564419
|
3-[2-[4-(2-amino-4-methylpyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
Show/Hide
|
C19H18N6O2
|
1
|
1 |
IC50 = 85.2 nM
|
|
|
CP0536712
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H14FN5OS
|
1
|
1 |
IC50 = 85.5 nM
|
|
|
CP0521573
|
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-fluoropyridin-2-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C18H13FN6OS
|
1
|
1 |
IC50 = 87.3 nM
|
|
|
CP0548749
|
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-2-(5-methyl-1,2-oxazol-3-yl)but-3-yn-2-ol
Show/Hide
|
C19H16N6O2
|
1
|
1 |
IC50 = 120 nM
|
|
|
CP0548751
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-methoxyphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C20H17N5O2S
|
1
|
1 |
IC50 = 120 nM
|
|
|
CP0550872
|
3-[2-[4-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
Show/Hide
|
C20H20N6O2
|
1
|
1 |
IC50 = 189.8 nM
|
|
|
CP0579800
|
4-[6-[2-(4-ethynylpyrimidin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C19H11N7
|
1
|
1 |
IC50 = 199.53 nM
|
|
|
CP0416712
|
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H14FN5OS
|
1
|
1 |
IC50 = 204 nM
|
|
|
CP0543831
|
4-[3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H14FN5OS
|
1
|
1 |
IC50 = 215 nM
|
|
|
CP0467967
|
4-[3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-methoxyphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C20H17N5O2S
|
1
|
1 |
IC50 = 216 nM
|
|
|
CP0548750
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H15N5OS
|
1
|
1 |
IC50 = 218 nM
|
|
|
CP0533528
|
4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-[3-hydroxy-3-(1,3-thiazol-2-yl)but-1-ynyl]benzonitrile
Show/Hide
|
C20H14N6OS
|
1
|
1 |
IC50 = 219 nM
|
|
|
CP0564418
|
1-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]cyclopentan-1-ol
Show/Hide
|
C18H17N5O
|
1
|
1 |
IC50 = 234 nM
|
|
|
CP0547303
|
4-(6-ethynylbenzimidazol-1-yl)pyrimidin-2-amine
Show/Hide
|
C13H9N5
|
1
|
1 |
IC50 = 251.19 nM
|
|
|
CP0533533
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-methoxyphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C20H17N5O2S
|
1
|
1 |
IC50 = 290 nM
|
|
|
CP0540938
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-(5-methyl-1,2-oxazol-3-yl)but-3-yn-2-ol
Show/Hide
|
C20H17N5O2
|
1
|
1 |
IC50 = 290 nM
|
|
|
CP0557770
|
4-[3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H15N5OS
|
1
|
1 |
IC50 = 303 nM
|
|
|
CP0577157
|
4-[6-[2-(4-ethynylpyridin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C20H12N6
|
1
|
1 |
IC50 = 316.23 nM
|
|
|
CP0536711
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H14FN5OS
|
1
|
1 |
IC50 = 319 nM
|
|
|
CP0438033
|
4-[3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-methylphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C20H17N5OS
|
1
|
1 |
IC50 = 335 nM
|
|
|
CP0521571
|
1-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]cyclobutan-1-ol
Show/Hide
|
C17H15N5O
|
1
|
1 |
IC50 = 388 nM
|
|
|
CP0536767
|
3-[2-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
Show/Hide
|
C19H17N5O2
|
1
|
1 |
IC50 = 410 nM
|
|
|
CP0564420
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-pyrazin-2-ylbut-3-yn-2-ol
Show/Hide
|
C20H16N6O
|
1
|
1 |
IC50 = 468 nM
|
|
|
CP0416715
|
1-[2-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]ethynyl]cyclopentan-1-ol
Show/Hide
|
C19H18N4O
|
1
|
1 |
IC50 = 475 nM
|
|
|
CP0562749
|
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2,4-difluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H13F2N5OS
|
1
|
1 |
IC50 = 641 nM
|
|
|
CP0426706
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-methylbut-3-yn-2-ol
Show/Hide
|
C17H16N4O
|
1
|
1 |
IC50 = 720 nM
|
|
|
CP0473924
|
1-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]cycloheptan-1-ol
Show/Hide
|
C20H21N5O
|
1
|
1 |
IC50 = 748 nM
|
|
|
CP0521572
|
1-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]cyclohexan-1-ol
Show/Hide
|
C19H19N5O
|
1
|
1 |
IC50 = 1570 nM
|
|
|
CP0575802
|
4-[6-[2-(4-methylpyrimidin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C18H13N7
|
1
|
1 |
IC50 = 1584.89 nM
|
|
|
CP0576331
|
4-[6-[2-(4-ethenylpyridin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C20H14N6
|
1
|
1 |
IC50 = 1584.89 nM
|
|
|
CP0578521
|
4-[6-[2-(4-ethenylpyrimidin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C19H13N7
|
1
|
1 |
IC50 = 1584.89 nM
|
|
|
CP0543833
|
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-2-pyrazin-2-ylbut-3-yn-2-ol
Show/Hide
|
C19H15N7O
|
1
|
1 |
IC50 = 1640 nM
|
|
|
CP0548747
|
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C20H17N5O2S
|
1
|
1 |
IC50 = 1750 nM
|
|
|
CP0426705
|
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C18H14N6OS
|
1
|
1 |
IC50 = 1860 nM
|
|
|
CP0479843
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-cyclohexylbut-3-yn-2-ol
Show/Hide
|
C22H24N4O
|
1
|
1 |
IC50 = 2030 nM
|
|
|
CP0438034
|
3-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[3-hydroxy-3-(1,3-thiazol-2-yl)but-1-ynyl]benzonitrile
Show/Hide
|
C20H14N6OS
|
1
|
1 |
IC50 = 2060 nM
|
|
|
CP0533529
|
4-[3-(2-amino-5-chloropyrrolo[2,3-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H14ClN5OS
|
1
|
1 |
IC50 = 2061 nM
|
|
|
CP0459478
|
4-[3-(2-amino-6-methyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C20H17N5OS
|
1
|
1 |
IC50 = 2204 nM
|
|
|
CP0438036
|
(2S)-4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-4-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H14FN5OS
|
1
|
1 |
IC50 = 2230 nM
|
|
|
CP0564411
|
1-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-3-(1,3-thiazol-2-yl)pent-1-yn-3-ol
Show/Hide
|
C19H16N6OS
|
1
|
1 |
IC50 = 2290 nM
|
|
|
CP0004106
|
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
Show/Hide
|
C28H26N4O3
|
1
|
1 |
IC50 = 2300 nM
|
|
|
CP0533532
|
3-[2-[4-(6-aminopyrrolo[2,3-b]pyridin-1-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
Show/Hide
|
C19H17N5O2
|
1
|
1 |
IC50 = 2481 nM
|
|
|
CP0543832
|
4-[3-(2-amino-4-methoxypyrrolo[2,3-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C20H17N5O2S
|
1
|
1 |
IC50 = 2484 nM
|
|
|
CP0905360
|
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclobutyl)methanone
Show/Hide
|
C15H15Cl2N3O
|
1
|
1 |
IC50 = 2900 nM
|
|
|
CP0580187
|
4-[6-[2-(6-ethynylpyridin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C20H12N6
|
1
|
1 |
IC50 = 3162.28 nM
|
|
|
CP0864827
|
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclohexyl)methanone
Show/Hide
|
C17H19Cl2N3O
|
1
|
1 |
IC50 = 3300 nM
|
|
|
CP0472094
|
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H15N5OS
|
1
|
1 |
IC50 = 3837 nM
|
|
|
CP0533531
|
4-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]-2-hydroxy-2-methyl-1-pyrrolidin-1-ylbut-3-yn-1-one
Show/Hide
|
C20H20N6O2
|
1
|
1 |
IC50 = 6160 nM
|
|
|
CP0568060
|
4-[6-[2-(6-ethynylpyrazin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C19H11N7
|
1
|
1 |
IC50 = 6309.57 nM
|
|
|
CP0580186
|
N-[3-[3-(2-aminopyrimidin-4-yl)benzimidazol-5-yl]prop-2-ynyl]prop-2-enamide
Show/Hide
|
C17H14N6O
|
1
|
1 |
IC50 = 6309.57 nM
|
|
|
CP0530513
|
3-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-1-(1,3-thiazol-2-yl)prop-2-yn-1-ol
Show/Hide
|
C18H13N5OS
|
1
|
1 |
IC50 = 6380 nM
|
|
|
CP0639989
|
1-(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)ethan-1-one
Show/Hide
|
C12H11Cl2N3O
|
1
|
1 |
IC50 = 8400 nM
|
|
|
CP0416713
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-(6-methoxypyridin-2-yl)but-3-yn-2-ol
Show/Hide
|
C22H19N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0426704
|
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-[2-(dimethylamino)ethoxy]phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C23H24N6O2S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0426707
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-hydroxy-N,N,2-trimethylbut-3-ynamide
Show/Hide
|
C19H19N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0438350
|
4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-[3-hydroxy-3-(1,3-thiazol-2-yl)but-1-ynyl]-N,N-dimethylbenzamide
Show/Hide
|
C22H20N6O2S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0438351
|
4-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]piperidin-4-ol
Show/Hide
|
C18H18N6O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0536714
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl]-2-hydroxy-2-methyl-1-pyrrolidin-1-ylbut-3-yn-1-one
Show/Hide
|
C21H21N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0542925
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-chlorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H14ClN5OS
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0554011
|
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-(methylamino)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C20H18N6OS
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0530512
|
4-[3-(2-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-2-fluorophenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C19H14FN5OS
|
1
|
1 |
IC50 = 10910 nM
|
|
|
CP0548748
|
4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-methylphenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
|
C20H17N5OS
|
1
|
1 |
IC50 = 11700 nM
|
|
|
CP0864828
|
1-(3-amino-4-bromo-5-methyl-1H-pyrazol-1-yl)ethan-1-one
Show/Hide
|
C6H8BrN3O
|
1
|
1 |
IC50 = 12500 nM
|
|
|
CP0579782
|
4-[6-[2-(2-ethenylpyridin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C20H14N6
|
1
|
1 |
IC50 = 19952.62 nM
|
|
|
CP0915203
|
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(phenyl)methanone
Show/Hide
|
C17H13Cl2N3O
|
1
|
1 |
IC50 = 23000 nM
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CP0876658
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(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclopropyl)methanone
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C14H13Cl2N3O
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1
|
1 |
IC50 = 24300 nM
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CP0574431
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4-[6-[2-(5-ethynylpyrimidin-2-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
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C19H11N7
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1
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1 |
IC50 = 25118.86 nM
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CP0426703
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4-[5-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-2-(2-methoxyethoxy)phenyl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
Show/Hide
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C22H21N5O3S
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1
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1 |
IC50 = 25830 nM
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CP0905359
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1-(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)propan-1-one
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C13H13Cl2N3O
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1
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1 |
IC50 = 27400 nM
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CP0579783
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4-[6-[2-(2-ethynylpyridin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
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C20H12N6
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1
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1 |
IC50 = 31622.78 nM
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CP0911844
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1-(5-amino-4-(3,4-dimethylphenyl)-3-methyl-1H-pyrazol-1-yl)ethan-1-one
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C14H17N3O
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1
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1 |
IC50 = 39600 nM
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CP0579469
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4-[6-[2-(2-ethenylpyrimidin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
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C19H13N7
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1
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1 |
IC50 = 39810.72 nM
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CP0580188
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4-[6-[2-(2-ethynylpyrimidin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
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C19H11N7
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1
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1 |
IC50 = 39810.72 nM
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CP0893469
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(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclopentyl)methanone
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C16H17Cl2N3O
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1
|
1 |
IC50 = 41000 nM
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CP0500658
|
4-(ethoxymethylene)isoquinoline-1,3(2H,4H)-dione
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C12H11NO3
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1
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1 |
IC50 > 50000 nM
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CP0576333
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4-[6-[2-(6-ethynylpyrimidin-4-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
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C19H11N7
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1
|
1 |
IC50 = 50118.72 nM
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CP0307611
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4H-isoquinoline-1,3-dione
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C9H7NO2
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1
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1 |
IC50 = 51000 nM
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CP0893471
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(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(pyridin-4-yl)methanone
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C16H12Cl2N4O
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1
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1 |
IC50 = 58200 nM
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CP0869606
|
SID24808657
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C10H10ClN3
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1
|
1 |
IC50 = 61100 nM
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CP0576332
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4-[6-[2-(5-ethynylpyridin-3-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C20H12N6
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1
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1 |
IC50 = 63095.73 nM
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CP0547305
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4-[6-[2-(6-ethenylpyridin-3-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
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C20H14N6
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1
|
1 |
IC50 = 79432.82 nM
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CP0571379
|
4-(6-ethylbenzimidazol-1-yl)pyrimidin-2-amine
Show/Hide
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C13H13N5
|
1
|
1 |
IC50 = 79432.82 nM
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CP0575603
|
4-[6-[2-(2-ethynylpyrimidin-5-yl)ethynyl]benzimidazol-1-yl]pyrimidin-2-amine
Show/Hide
|
C19H11N7
|
1
|
1 |
IC50 = 79432.82 nM
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CP0400398
|
2,7-naphthyridine-1,3,6,8-tetrone
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C8H8N2O4
|
1
|
1 |
IC50 = 90000 nM
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|
|
CP0058616
|
5-Hydroxy-2-methyl-[1,4]naphthoquinone
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C11H8O3
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0398575
|
5,7-dichloroquinazoline-2,4(1H,3H)-dione
Show/Hide
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C8H4Cl2N2O2
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0500659
|
4-(thiophen-2-ylmethylene)isoquinoline-1,3(2H,4H)-dione
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|
C14H9NO2S
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0535128
|
1,2-dihydroisoquinolin-3(4H)-one
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C9H9NO
|
1
|
1 |
IC50 > 100000 nM
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|
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CP0357240
|
5-methyl-4-phenyl-1H-pyrazol-3-amine
Show/Hide
|
C10H11N3
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0852538
|
1-(3-amino-4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-1-yl)ethan-1-one
Show/Hide
|
C12H11Cl2N3O
|
1
|
1 |
IC50 > 100000 nM
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|
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CP0852539
|
4-(3,4-dichlorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine
Show/Hide
|
C11H11Cl2N3
|
1
|
1 |
IC50 > 100000 nM
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|
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CP0852540
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N-(4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-yl)-2,2,2-trifluoroacetamide
Show/Hide
|
C12H8Cl2F3N3O
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0852541
|
4-(4-bromophenyl)-5-methyl-1H-pyrazol-3-amine
Show/Hide
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C10H10BrN3
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0852542
|
N-(5-chloro-9H-pyrido[3,4-b]indol-7-yl)nicotinamide
Show/Hide
|
C17H11ClN4O
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0852543
|
1-(5-amino-4-(3,4-dichlorophenyl)-3-ethyl-1H-pyrazol-1-yl)ethan-1-one
Show/Hide
|
C13H13Cl2N3O
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0852545
|
4-(benzo[d][1,3]dioxol-5-yl)-5-methyl-1H-pyrazol-3-amine
Show/Hide
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C11H11N3O2
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1
|
1 |
IC50 > 100000 nM
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|
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CP0852546
|
5-methyl-4-p-tolyl-1H-pyrazol-3-amine
Show/Hide
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C11H13N3
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0852547
|
1-(5-amino-3-methyl-4-(3-(trifluoromethyl)phenyl)-1H-pyrazol-1-yl)ethan-1-one
Show/Hide
|
C13H12F3N3O
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0864824
|
1-(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)butan-1-one
Show/Hide
|
C14H15Cl2N3O
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0864825
|
(5-amino-4-(4-chlorophenyl)-3-methyl-1H-pyrazol-1-yl)(cyclopropyl)methanone
Show/Hide
|
C14H14ClN3O
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0864826
|
5-methyl-4-(naphthalen-2-yl)-1H-pyrazol-3-amine
Show/Hide
|
C14H13N3
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0864830
|
N-[4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-yl]pyridine-2-carboxamide
Show/Hide
|
C16H12Cl2N4O
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0864831
|
1-(5-amino-4-(4-chlorophenyl)-3-methyl-1H-pyrazol-1-yl)ethan-1-one
Show/Hide
|
C12H12ClN3O
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0876657
|
4-(3,4-dichlorophenyl)-1,5-dimethyl-1H-pyrazol-3-amine
Show/Hide
|
C11H11Cl2N3
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0876659
|
5-methyl-4-(3-methylphenyl)-1H-pyrazol-3-amine
Show/Hide
|
C11H13N3
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0876660
|
1-(5-amino-4-bromo-3-methyl-1H-pyrazol-1-yl)ethan-1-one
Show/Hide
|
C6H8BrN3O
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0880318
|
4-(3-chlorophenyl)-5-methyl-1H-pyrazol-3-amine
Show/Hide
|
C10H10ClN3
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0880319
|
5-methyl-4-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
Show/Hide
|
C11H10F3N3
|
1
|
1 |
IC50 > 100000 nM
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|
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CP0893470
|
(3-amino-4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-1-yl)(cyclobutyl)methanone
Show/Hide
|
C15H15Cl2N3O
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0893477
|
tert-butyl 5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazole-1-carboxylate
Show/Hide
|
C15H17Cl2N3O2
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0893478
|
5-amino-4-(3,4-dichlorophenyl)-N-ethyl-3-methyl-1H-pyrazole-1-carboxamide
Show/Hide
|
C13H14Cl2N4O
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0893479
|
4-(3-bromophenyl)-5-methyl-1H-pyrazol-3-amine
Show/Hide
|
C10H10BrN3
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0893480
|
(5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl)(pyridin-3-yl)methanone
Show/Hide
|
C16H12Cl2N4O
|
1
|
1 |
IC50 > 100000 nM
|
|
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CP0905361
|
(3-amino-4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-1-yl)(pyridin-3-yl)methanone
Show/Hide
|
C16H12Cl2N4O
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0905362
|
5-methyl-4-(3-(trifluoromethoxy)phenyl)-1H-pyrazol-3-amine
Show/Hide
|
C11H10F3N3O
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0905363
|
4-(4-(benzyloxy)phenyl)-5-methyl-1H-pyrazol-3-amine
Show/Hide
|
C17H17N3O
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0911845
|
1-(5-amino-4-(3-chlorophenyl)-3-methyl-1H-pyrazol-1-yl)ethan-1-one
Show/Hide
|
C12H12ClN3O
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0915202
|
4-(3,5-bis(trifluoromethyl)phenyl)-5-methyl-1H-pyrazol-3-amine
Show/Hide
|
C12H9F6N3
|
1
|
1 |
IC50 > 100000 nM
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|
|
CP0915204
|
4-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-amine
Show/Hide
|
C10H9Cl2N3
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0915205
|
5-(3,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-amine
Show/Hide
|
C10H9Cl2N3
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0945628
|
4-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3-amine
Show/Hide
|
C12H15N3
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0580166
|
N-[3-[3-(2-aminopyrimidin-4-yl)benzimidazol-5-yl]propyl]acetamide
Show/Hide
|
C16H18N6O
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0382724
|
3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)-N-[2-[2-[2-[2-[[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]propanamide
Show/Hide
|
C49H54BF2N7O7
|
1
|
1 |
Kd = 352 nM
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|
|
CP0382649
|
3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)-N-[2-[2-[2-[2-[[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-methylamino]ethoxy]ethoxy]ethoxy]ethyl]propanamide
Show/Hide
|
C50H56BF2N7O7
|
1
|
1 |
Kd = 445 nM
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