Brief Information of the Compound and Protein
Compound Name
3-[2-[4-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
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PubChem ID
CID: 141758865
Canonical SMILES
CCc1nc(N)nc2n(ccc12)-c1ccnc(c1)C#CC1(O)CCN(C)C1=O
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Compound Formula C20H20N6O2
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase unique family
Uniprot ID
Q99558
Gene Name
MAP3K14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 189.8 nM
   TI
   LI
   LO
   TS