Brief Information of the Compound and Protein
Compound Name
(2R)-4-[1-(2-amino-5-chloropyrimidin-4-yl)-2,3-dihydroindol-6-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol
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PubChem ID
CID: 57525824
Canonical SMILES
C[C@@](O)(C#Cc1ccc2CCN(c2c1)c1nc(N)ncc1Cl)c1nccs1
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Compound Formula C19H16ClN5OS
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase unique family
Uniprot ID
Q99558
Gene Name
MAP3K14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 15.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.2 nM