Brief Information of the Compound and Protein
Compound Name
3-[2-[4-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)pyridin-2-yl]ethynyl]-3-hydroxy-1-methylpyrrolidin-2-one
    Show/Hide
PubChem ID
CID: 141758940
Canonical SMILES
CN1CCC(O)(C#Cc2cc(ccn2)-n2ccc3cnc(N)nc23)C1=O
    Show/Hide
Compound Formula C18H16N6O2
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase unique family
Uniprot ID
Q99558
Gene Name
MAP3K14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 26.1 nM
   TI
   LI
   LO
   TS