| Compound ID |
Compound Name |
Compound Formula |
|
CP0056636
|
10-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-fluoro-1,2,10-triazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
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|
C17H19FN4O
|
1
|
| 1 |
EC50 = 178 nM
|
|
|
|
CP0056637
|
10-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-chloro-1,2,10-triazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
Show/Hide
|
C17H19ClN4O
|
1
|
| 1 |
EC50 = 178 nM
|
|
|
|
CP0056638
|
10-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1,3,10-triazatricyclo[6.4.1.04,13]trideca-4,6,8(13)-triene-2,9-dione
Show/Hide
|
C17H20N4O2
|
1
|
| 1 |
EC50 = 178 nM
|
|
|
|
CP0120281
|
10-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-methoxy-1,2,10-triazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
EC50 = 178 nM
|
|
|
|
CP0120282
|
10-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1,2,10-triazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
Show/Hide
|
C17H20N4O
|
1
|
| 1 |
EC50 = 178 nM
|
|
|
|
CP0157937
|
10-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
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|
C18H21N3O
|
1
|
| 1 |
EC50 = 178 nM
|
|
|
|
CP0281107
|
4-amino-5-chloro-2-methoxy-N-(3-methoxypiperidin-4-yl)benzamide
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|
C14H20ClN3O3
|
2
|
| 1 |
EC50 = 2300 nM
|
|
|
| 2 |
IC50 = 1600 nM
|
|
|
|
CP0151545
|
4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-2-(3-methoxyphenyl)cyclohexyl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
Show/Hide
|
C28H38ClN3O5
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 159 nM
|
|
|
|
CP0384747
|
(3R)-5'-chlorospiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
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|
C15H16ClN3O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0463847
|
(3R)-N-pyrrolo[1,2-a]pyrazin-1-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H19N5O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0549706
|
(3R)-6'-chlorospiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
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|
C15H16ClN3O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0569425
|
(3R)-7'-methylspiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
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|
C16H19N3O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0388562
|
(3R)-N-(3-chloropyrazolo[1,5-a]pyrimidin-5-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H17ClN6O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0398635
|
(3R)-N-(3-methylpyrrolo[1,2-a]pyrazin-1-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C17H21N5O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0415426
|
N-(1,3-benzothiazol-2-yl)spiro[1-azabicyclo[3.2.1]octane-6,5'-4H-1,3-oxazole]-2'-amine
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|
C16H18N4OS
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0404086
|
(3R)-5'-methylspiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C16H19N3O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0451446
|
(3R)-N-quinolin-2-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C18H20N4O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0053464
|
3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)butyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one
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|
C25H32N6O
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0536869
|
(3R)-7'-chlorospiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C15H16ClN3O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0022161
|
CAS_40796-97-2
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|
C15H17Cl2NO2
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
Ki = 2.5 nM
|
|
|
|
CP0465199
|
N-(4-phenyl-1,3-thiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C18H20N4OS
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0404312
|
(3R)-5'-(trifluoromethyl)spiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C16H16F3N3O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0530704
|
(3R)-6'-methoxyspiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C16H19N3O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0549708
|
(3R)-8'-chlorospiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C15H16ClN3O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0451437
|
N-(4-methoxy-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C17H20N4O2S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0404087
|
(3R)-6'-methylspiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C16H19N3O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0022281
|
(3R)-N-pyridin-2-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0002604
|
(3R)-spiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0475483
|
3-Amino-8-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
IC50 = 15.6 nM
|
|
|
|
CP0451436
|
N-pyridin-2-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0482413
|
(3R)-7'-(trifluoromethyl)spiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C16H16F3N3O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0181346
|
4-amino-5-chloro-N-((3R,4S)-1-(((1S,2S)-2-hydroxy-2-(3-hydroxyphenyl)cyclohexyl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
Show/Hide
|
C27H36ClN3O5
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0566226
|
N-(5-methoxy-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C17H20N4O2S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0451973
|
N-(1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H18N4OS
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0458720
|
(3R)-N-(1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H18N4OS
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0472689
|
7-Acetyl-3-amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5, 6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C28H33N7O2S
|
1
|
| 1 |
IC50 = 22.1 nM
|
|
|
|
CP0428010
|
2-[4-(4-Quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8-tetrahydro-3Hquinazolin-4-one
Show/Hide
|
C25H31N5O
|
1
|
| 1 |
IC50 = 24.6 nM
|
|
|
|
CP0446575
|
N-(1,3-thiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C12H16N4OS
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0479074
|
3-Amino-5,6-dimethyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H30N6OS
|
1
|
| 1 |
IC50 = 26.7 nM
|
|
|
|
CP0562933
|
(3R)-N-pyrrolo[2,1-f][1,2,4]triazin-4-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H18N6O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0451433
|
N-(1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.1]heptane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H16N4OS
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0454497
|
3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7, 8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C26H30N6OS2
|
1
|
| 1 |
IC50 = 41.4 nM
|
|
|
|
CP0482414
|
(3R)-5',6'-dibromospiro[1-azabicyclo[2.2.2]octane-3,2'-3H-imidazo[2,1-b][1,3]oxazole]
Show/Hide
|
C11H13Br2N3O
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0497743
|
2-[3-(4-Quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C26H29N5OS2
|
1
|
| 1 |
IC50 = 44.2 nM
|
|
|
|
CP0528014
|
3-Amino-6-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
IC50 = 45.6 nM
|
|
|
|
CP0354715
|
3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3H-quinazolin-4-one
Show/Hide
|
C25H28N6O
|
1
|
| 1 |
IC50 = 45.7 nM
|
|
|
|
CP0472688
|
3-Amino-6-hydroxy-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
|
C25H32N6O2
|
1
|
| 1 |
IC50 = 46.5 nM
|
|
|
|
CP0493375
|
3-Amino-6-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5, 6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
|
C26H34N6O
|
1
|
| 1 |
IC50 = 48.3 nM
|
|
|
|
CP0406049
|
3-Amino-5,6-dimethyl-2-[3-(4-quinolin-2-ylpiperazin-1-yl)-propylthio]-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C24H28N6OS2
|
1
|
| 1 |
IC50 = 48.4 nM
|
|
|
|
CP0414318
|
(3R)-N-thieno[3,2-d]pyrimidin-4-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H17N5OS
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0526306
|
3-Amino-5,6-dimethyl-2-[3-[4-(4-methylquinolin-2-yl)piperazin-1-yl]propylthio]-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H30N6OS2
|
1
|
| 1 |
IC50 = 50.5 nM
|
|
|
|
CP0497744
|
3-Amino-5-fluoro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
Show/Hide
|
C25H27FN6O
|
1
|
| 1 |
IC50 = 50.6 nM
|
|
|
|
CP0493343
|
3-Amino-2-[4-[4-(3-hydroxyquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
|
C25H32N6O2
|
1
|
| 1 |
IC50 = 52.6 nM
|
|
|
|
CP0446031
|
(3R)-N-furo[3,2-c]pyridin-4-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H18N4O2
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0479068
|
3-Amino-2-[4-[4-(7-hydroxyquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
|
C25H32N6O2
|
1
|
| 1 |
IC50 = 55.2 nM
|
|
|
|
CP0406048
|
3-Amino-2-[4-[4-(4-methylquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
|
C26H34N6O
|
1
|
| 1 |
IC50 = 59.1 nM
|
|
|
|
CP0454496
|
3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3Hpyrido[3,2-d]pyrimidin-4-one
Show/Hide
|
C23H25N7OS
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0404085
|
5',6'-dibromospiro[1-azabicyclo[2.2.2]octane-3,2'-3H-imidazo[2,1-b][1,3]oxazole]
Show/Hide
|
C11H13Br2N3O
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0493374
|
3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7-trihydro-3H-cyclopenta[d]pyrimidin-4-one
Show/Hide
|
C24H30N6O
|
1
|
| 1 |
IC50 = 62.1 nM
|
|
|
|
CP0475500
|
3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
|
C24H30N6OS
|
1
|
| 1 |
IC50 = 63.8 nM
|
|
|
|
CP0524112
|
3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3Hpyrido[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H25N7OS
|
1
|
| 1 |
IC50 = 64.8 nM
|
|
|
|
CP0497747
|
3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3H-quinazolin-4-one
Show/Hide
|
C24H26N6OS
|
1
|
| 1 |
IC50 = 69.9 nM
|
|
|
|
CP0475482
|
7-Acetyl-3-amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyridin-4-one
Show/Hide
|
C27H31N7O2S2
|
1
|
| 1 |
IC50 = 77.6 nM
|
|
|
|
CP0497769
|
3-Amino-8-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
Show/Hide
|
C25H27ClN6O
|
1
|
| 1 |
IC50 = 83.1 nM
|
|
|
|
CP0497766
|
3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8,9-pentahydro-3H-cyclohepta[d]pyrimidin-4-one
Show/Hide
|
C26H34N6O
|
1
|
| 1 |
IC50 = 84.8 nM
|
|
|
|
CP0401035
|
(3R)-N-(4-phenylpyridin-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0475499
|
3-Amino-2-[2-(4-quinolin-2-ylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
|
C22H26N6O
|
1
|
| 1 |
IC50 = 86.6 nM
|
|
|
|
CP0521979
|
3-Amino-2-[3-(4-benzothiazol-2-ylpiperazin-1-yl)propylthio]-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C22H26N6OS3
|
1
|
| 1 |
IC50 = 87.6 nM
|
|
|
|
CP0527689
|
3-Amino-7-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
|
C26H34N6O
|
1
|
| 1 |
IC50 = 97.9 nM
|
|
|
|
CP0523786
|
3-Amino-6-fluoro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
Show/Hide
|
C25H27FN6O
|
1
|
| 1 |
IC50 = 99.4 nM
|
|
|
|
CP0526309
|
3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7, 8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyridin-4-one
Show/Hide
|
C25H29N7OS2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0532773
|
N-(7-chloropyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,4'-5H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H17ClN6O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0541549
|
(3R,4R)-N-pyrrolo[2,1-f][1,2,4]triazin-4-ylspiro[1-azabicyclo[2.2.1]heptane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C14H16N6O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0446621
|
N-phenylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0414319
|
(3R)-N-imidazo[1,2-b]pyridazin-6-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H18N6O
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0508081
|
(3R)-N-(7-fluoropyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H17FN6O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0039517
|
4-amino-5-chloro-N-((3R,4S)-1-(((1R,2R)-2-hydroxy-2-(3-hydroxyphenyl)cyclohexyl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
Show/Hide
|
C27H36ClN3O5
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0003085
|
(3R)-N-isoquinolin-3-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C18H20N4O
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0446622
|
(3R,4R)-N-(1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.1]heptane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H16N4OS
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0569426
|
(3R)-6'-(trifluoromethyl)spiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C16H16F3N3O
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0398634
|
(3R)-N-thieno[2,3-d]pyrimidin-4-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H17N5OS
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0071258
|
4-amino-5-chloro-N-((3R,4S)-1-(((1R,2R)-2-hydroxy-2-(3-methoxyphenyl)cyclohexyl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
Show/Hide
|
C28H38ClN3O5
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0415429
|
(5R)-N-(1,3-benzothiazol-2-yl)spiro[1-azabicyclo[3.2.1]octane-6,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H18N4OS
|
1
|
| 1 |
IC50 = 950 nM
|
|
|
|
CP0095685
|
4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-2-(3-hydroxyphenyl)cyclohexyl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
Show/Hide
|
C27H36ClN3O5
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0166661
|
4-amino-5-chloro-N-((3S,4R)-1-(((1R,2R)-2-hydroxy-2-(3-hydroxyphenyl)cyclohexyl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
Show/Hide
|
C27H36ClN3O5
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0432227
|
(3R)-N-isoquinolin-1-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C18H20N4O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0087146
|
4-amino-5-chloro-N-((3R,4S)-1-(((1S,2S)-2-hydroxy-2-(3-methoxyphenyl)cyclohexyl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
Show/Hide
|
C28H38ClN3O5
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0508091
|
(3R)-N-(6-bromopyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H17BrN6O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0455068
|
N-pyridin-3-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0095682
|
4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-hydroxyphenyl)cyclohexyl)methyl)(methyl)amino)ethyl)-2-methoxybenzamide
Show/Hide
|
C24H32ClN3O4
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0071257
|
4-amino-5-chloro-N-((3S,4R)-1-(((1R,2R)-2-hydroxy-2-(3-methoxyphenyl)cyclohexyl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide
Show/Hide
|
C28H38ClN3O5
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0647728
|
rac-cis-4-amino-5-chloro-N-(2-(((2-hydroxy-2-(3-hydroxyphenyl)cyclohexyl)methyl)(methyl)amino)ethyl)-2-methoxybenzamide
Show/Hide
|
C24H32ClN3O4
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0281106
|
4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hydroxyphenyl)cyclohexyl)methyl)(methyl)amino)ethyl)-2-methoxybenzamide
Show/Hide
|
C24H32ClN3O4
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0039516
|
4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-methoxyphenyl)cyclohexyl)methyl)(methyl)amino)ethyl)-2-methoxybenzamide
Show/Hide
|
C25H34ClN3O4
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0446619
|
N-(6-methyl-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C17H20N4OS
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0508089
|
(3R)-N-(3-methylimidazo[4,5-c]pyridin-6-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H20N6O
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0517624
|
(3R)-N-(1-methylimidazo[4,5-c]pyridin-6-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H20N6O
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0226668
|
4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-methoxyphenyl)cyclohexyl)methyl)(methyl)amino)ethyl)-2-methoxybenzamide
Show/Hide
|
C25H34ClN3O4
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0408939
|
(3R)-N-(5-bromopyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H17BrN6O
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0066095
|
1-(2'-fluorobiphenyl-4-yl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C22H28FN3O
|
1
|
| 1 |
IC50 = 5700 nM
|
|
|
|
CP0288507
|
1-(4'-fluorobiphenyl-4-yl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C22H28FN3O
|
1
|
| 1 |
IC50 = 5800 nM
|
|
|
|
CP0446573
|
(3S)-N-(1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H18N4OS
|
1
|
| 1 |
IC50 = 7300 nM
|
|
|
|
CP0269306
|
1-(2'-methoxybiphenyl-4-yl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
IC50 = 7800 nM
|
|
|
|
CP0135912
|
1-(biphenyl-4-yl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C22H29N3O
|
1
|
| 1 |
IC50 = 7900 nM
|
|
|
|
CP0531146
|
N-(6-chloro-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H17ClN4OS
|
1
|
| 1 |
IC50 = 8100 nM
|
|
|
|
CP0005884
|
(3R)-N-(6-methoxy-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C17H20N4O2S
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0389076
|
(3S)-5',6'-dibromospiro[1-azabicyclo[2.2.2]octane-3,2'-3H-imidazo[2,1-b][1,3]oxazole]
Show/Hide
|
C11H13Br2N3O
|
1
|
| 1 |
IC50 = 9700 nM
|
|
|
|
CP0384752
|
(3R)-5'-(4-methoxyphenyl)spiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C22H23N3O2
|
1
|
| 1 |
IC50 = 10400 nM
|
|
|
|
CP0446620
|
2-(spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-ylamino)-1,3-benzothiazol-6-ol
Show/Hide
|
C16H18N4O2S
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0463848
|
(3R)-N-(6-bromopyrrolo[1,2-a]pyrazin-1-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H18BrN5O
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0482401
|
(3S)-spiro[1-azabicyclo[2.2.2]octane-3,2'-1H-[1,3]oxazolo[3,2-a]benzimidazole]
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0510737
|
N-(6-ethoxy-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C18H22N4O2S
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0468086
|
4-[[(3R)-spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-yl]amino]pyrrolo[2,1-f][1,2,4]triazine-7-carbonitrile
Show/Hide
|
C16H17N7O
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
|
CP0446574
|
N-(6-methoxy-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C17H20N4O2S
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
|
CP0520694
|
N-(5-phenyl-1,3-thiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C18H20N4OS
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0465158
|
(3R)-N-(5-phenylpyridin-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
IC50 = 22000 nM
|
|
|
|
CP0510735
|
N-(5,6-dimethoxy-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C18H22N4O3S
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0446109
|
(3R)-N-(5,7-dibromopyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H16Br2N6O
|
1
|
| 1 |
IC50 = 28000 nM
|
|
|
|
CP0388575
|
(3R)-N-(7-chloropyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H17ClN6O
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
|
CP0035594
|
1-(6-(2-fluorophenyl)pyridin-3-yl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C21H27FN4O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0035744
|
1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl)urea
Show/Hide
|
C21H27FN4O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0066093
|
1-(2,2'-bipyridin-5-yl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C20H27N5O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0135706
|
1-(6'-fluoro-2,3'-bipyridin-5-yl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C20H26FN5O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0135708
|
1-(4-(6-fluoropyridin-3-yl)phenyl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C21H27FN4O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0135915
|
1-(6-(2-methoxyphenyl)pyridin-3-yl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C22H30N4O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0269304
|
1-(6-phenylpyridin-3-yl)-3-(4-(piperidin-1-yl)butyl)urea
Show/Hide
|
C21H28N4O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0269311
|
1-(4-Piperidin-1-ylbutyl)-3-(4-pyridin-2-ylphenyl)urea
Show/Hide
|
C21H28N4O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0003419
|
N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]-5-(1,4-oxazepan-4-yl)pentanamide
Show/Hide
|
C20H28N4O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0003699
|
5-(4-acetyl-1,4-diazepan-1-yl)-N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]-2-methylpentanamide
Show/Hide
|
C23H33N5O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0004176
|
5-(azepan-1-yl)-N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]pentanamide
Show/Hide
|
C21H30N4O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0008064
|
N-[5-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-piperidin-1-ylpentanamide
Show/Hide
|
C19H25FN4O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0009928
|
N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]-5-piperidin-1-ylpentanamide
Show/Hide
|
C20H28N4O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0009929
|
N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]-5-morpholin-4-ylpentanamide
Show/Hide
|
C19H26N4O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0010006
|
N-[5-(2-methoxyphenyl)-1H-pyrazol-3-yl]-5-piperidin-1-ylpentanamide
Show/Hide
|
C20H28N4O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0011420
|
5-(4-acetyl-1,4-diazepan-1-yl)-N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]pentanamide
Show/Hide
|
C22H31N5O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0012399
|
N-[5-(4-bromophenyl)-1H-pyrazol-3-yl]-5-piperidin-1-ylpentanamide
Show/Hide
|
C19H25BrN4O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0003287
|
N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutanamide
Show/Hide
|
C19H26N4O2
|
1
|
| 1 |
IC50 > 31622.78 nM
|
|
|
|
CP0006365
|
4-(azepan-1-yl)-N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]butanamide
Show/Hide
|
C20H28N4O2
|
1
|
| 1 |
IC50 > 31622.78 nM
|
|
|
|
CP0408941
|
(3R)-N-(7-bromopyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C15H17BrN6O
|
1
|
| 1 |
IC50 = 34000 nM
|
|
|
|
CP0451435
|
N-(1,3-benzothiazol-5-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C16H18N4OS
|
1
|
| 1 |
IC50 = 41000 nM
|
|
|
|
CP0510738
|
N-(6-methoxy-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,4'-5H-1,3-oxazole]-2'-amine
Show/Hide
|
C17H20N4O2S
|
1
|
| 1 |
IC50 = 47000 nM
|
|
|
|
CP0465198
|
N-pyridin-4-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
IC50 = 58000 nM
|
|
|
|
CP0432226
|
N-(7-chloropyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,6'-4,5-dihydro-1,3-oxazine]-2'-amine
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C16H19ClN6O
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1
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| 1 |
IC50 = 61000 nM
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CP0415428
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N-(6-methoxy-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,6'-4,5-dihydro-1,3-oxazine]-2'-amine
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C18H22N4O2S
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1
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| 1 |
IC50 = 64000 nM
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CP0508090
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(3R)-N-(7-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
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C16H20N6O
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1
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| 1 |
IC50 = 71000 nM
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CP0377475
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(3R)-N-(7-methylpyrrolo[2,3-d]pyrimidin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
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C16H20N6O
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1
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| 1 |
IC50 = 86000 nM
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CP0504421
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(3S)-N-(7-chloropyrrolo[2,1-f][1,2,4]triazin-4-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
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C15H17ClN6O
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1
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| 1 |
IC50 = 87000 nM
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CP0415427
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(3S)-N-(6-methoxy-1,3-benzothiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
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C17H20N4O2S
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1
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| 1 |
IC50 > 97000 nM
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CP0000589
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Alcuronium
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C44H50N4O2+2
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2
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| 1 |
IC50 > 100000 nM
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| 2 |
Ki > 100000 nM
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CP0633393
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[(20-{[dimethyl(prop-2-en-1-yl)azaniumyl]methyl}-3,13-diazapentacyclo[11.7.0.0^{3,11}.0^{4,9}.0^{14,19}]icosa-1(20),4,6,8,10,14(19),15,17-octaen-10-yl)methyl]dimethylprop-2-en-1-ylazanium dibromide
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C30H38Br2N4
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2
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| 1 |
IC50 > 100000 nM
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| 2 |
Ki > 100000 nM
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CP0633395
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(1S,9R,18R,19S,21R,22R,23R,25R,32S,34R,35R,36S)-15,31-dibenzyl-24-phenyl-10,26-dioxa-8,15,24,31-tetraazaundecacyclo[29.5.2.0^{1,32}.0^{2,7}.0^{8,36}.0^{9,22}.0^{13,21}.0^{15,19}.0^{18,23}.0^{25,35}.0^{29,34}]octatriaconta-2,4,6,12,28-pentaene-15,31-diium dibromide
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C52H56Br2N4O2
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2
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| 1 |
IC50 = 100000 nM
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| 2 |
Ki = 100000 nM
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CP0633631
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(1S,9R,18R,19S,21R,22R,23R,25R,32S,34R,35R,36S)-24-phenyl-15,31-bis(prop-2-en-1-yl)-10,26-dioxa-8,15,24,31-tetraazaundecacyclo[29.5.2.0^{1,32}.0^{2,7}.0^{8,36}.0^{9,22}.0^{13,21}.0^{15,19}.0^{18,23}.0^{25,35}.0^{29,34}]octatriaconta-2,4,6,12,28-pentaene-15,31-diium dibromide
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C44H52Br2N4O2
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2
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| 1 |
IC50 = 100000 nM
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| 2 |
Ki = 100000 nM
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CP0633633
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(1S,9R,18R,19S,21R,22R,23R,25R,32S,34R,35R,36S)-15,31-bis[(4-nitrophenyl)methyl]-24-phenyl-10,26-dioxa-8,15,24,31-tetraazaundecacyclo[29.5.2.0^{1,32}.0^{2,7}.0^{8,36}.0^{9,22}.0^{13,21}.0^{15,19}.0^{18,23}.0^{25,35}.0^{29,34}]octatriaconta-2,4,6,12,28-pentaene-15,31-diium dibromide
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C52H54Br2N6O6
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1
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| 1 |
IC50 > 100000 nM
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CP0633634
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(1S,9R,18R,19S,21R,22R,23R,25R,32S,34R,35R,36S)-15,31-bis[2-(acetyloxy)ethyl]-24-phenyl-10,26-dioxa-8,15,24,31-tetraazaundecacyclo[29.5.2.0^{1,32}.0^{2,7}.0^{8,36}.0^{9,22}.0^{13,21}.0^{15,19}.0^{18,23}.0^{25,35}.0^{29,34}]octatriaconta-2,4,6,12,28-pentaene-15,31-diium dibromide
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C46H56Br2N4O6
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2
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| 1 |
IC50 > 100000 nM
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| 2 |
Ki > 100000 nM
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CP0633635
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toxiferine
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C40H46Cl2N4O2
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2
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| 1 |
IC50 > 100000 nM
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| 2 |
Ki > 100000 nM
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CP0633848
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(1S,9R,18R,19S,21R,22R,23R,25R,32S,34R,35R,36S)-15,31-bis[(2E)-but-2-en-1-yl]-24-phenyl-10,26-dioxa-8,15,24,31-tetraazaundecacyclo[29.5.2.0^{1,32}.0^{2,7}.0^{8,36}.0^{9,22}.0^{13,21}.0^{15,19}.0^{18,23}.0^{25,35}.0^{29,34}]octatriaconta-2,4,6,12,28-pentaene-15,31-diium dibromide
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C46H56Br2N4O2
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1
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| 1 |
IC50 = 100000 nM
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CP0633850
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trimethyl({20-[(trimethylazaniumyl)methyl]-3,13-diazapentacyclo[11.7.0.0^{3,11}.0^{4,9}.0^{14,19}]icosa-1(20),4,6,8,10,14(19),15,17-octaen-10-yl}methyl)azanium diiodide
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C26H34I2N4
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2
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| 1 |
IC50 > 100000 nM
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| 2 |
Ki > 100000 nM
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CP0451430
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(E)-N-(6-methoxy-1,3-benzothiazol-2-yl)-3-methylspiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-imine
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C18H22N4O2S
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1
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| 1 |
IC50 > 100000 nM
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CP0379594
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3-Amino-7-nitro-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3H-quinazolin-4-one
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C24H25N7O3S
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1
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| 1 |
IC50 > 100 nM
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CP0386016
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3-Amino-5,6-dimethyl-2-[3-(4-pyridin-2-ylpiperazin-1-yl)propylthio]-3H-thieno[2,3-d]pyrimidin-4-one
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C20H26N6OS2
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1
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| 1 |
IC50 > 100 nM
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CP0454499
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3-Amino-6-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
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C25H27ClN6O
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1
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| 1 |
IC50 > 100 nM
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CP0454512
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3-Amino-5-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
Show/Hide
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C26H30N6O
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1
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| 1 |
IC50 > 100 nM
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CP0454513
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3-Amino-2-[4-[4-(3-methylquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
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C26H34N6O
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1
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| 1 |
IC50 > 100 nM
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CP0468972
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3-Amino-5-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
Show/Hide
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C25H27ClN6O
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1
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| 1 |
IC50 > 100 nM
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CP0468974
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3-Amino-2-[2-(4-quinolin-2-ylpiperazin-1-yl)ethyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
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C23H28N6O
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1
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| 1 |
IC50 > 100 nM
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CP0475498
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3-Amino-2-[4-[4-(2,3-dihydro-1H-cyclopenta[c]quinolin-4-yl)-piperazin-1-yl]butyl]-5,6,7,8-tequinazolintrahydro-3H--4-one
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C28H36N6O
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1
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| 1 |
IC50 > 100 nM
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CP0493344
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3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
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C24H30N6O
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1
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| 1 |
IC50 > 100 nM
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CP0493377
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3-Amino-7-fluoro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
Show/Hide
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C25H27FN6O
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1
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| 1 |
IC50 > 100 nM
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CP0493380
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3-Amino-2-[4-[4-(6-hydroxyquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
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C25H32N6O2
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1
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| 1 |
IC50 > 100 nM
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CP0502278
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3-Amino-7-chloro-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3Hquinazolin-4-one
Show/Hide
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C25H27ClN6O
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1
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| 1 |
IC50 > 100 nM
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CP0502280
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5-Amino-2-[5-(4-quinolin-2-ylpiperazin-1-yl)pentyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
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C26H34N6O
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1
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| 1 |
IC50 > 100 nM
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CP0521978
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3-Amino-2-[4-[4-(3,4-dimethylquinolin-2-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
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C27H36N6O
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1
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| 1 |
IC50 > 100 nM
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CP0523785
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5,6-Dimethyl-2-[3-(4-quinolin-2-yl-piperazin-1-yl)propylthio]-3H-thieno[2,3-d]pyrimidin-4-one
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C24H27N5OS2
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1
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| 1 |
IC50 > 100 nM
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CP0524111
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3-Amino-5,6-dimethyl-2-[3-[4-(5,6,7,8-tetrahydroquinolin-2-yl)-piperazin-1-yl]propylthio]-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
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C24H32N6OS2
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1
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| 1 |
IC50 > 100 nM
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CP0526307
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3-Amino-5,6-dimethyl-2-[3-(4-phenanthridin-6-ylpiperazin-1-yl)-propylthio]-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
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C28H30N6OS2
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1
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| 1 |
IC50 > 100 nM
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CP0527690
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3-Amino-2-[4-[4-(7,8,9,10-tetrahydrophenanthridin-6-yl)piperazin-1-yl]butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
Show/Hide
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C29H38N6O
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1
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| 1 |
IC50 > 100 nM
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CP0531865
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3-Amino-5,6-dimethyl-2-[3-[4-(3-phenylquinoxalin-2-yl)piperazin-1-yl]propylthio]-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
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C29H31N7OS2
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1
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| 1 |
IC50 > 100 nM
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CP0047123
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1,4-diazabicyclo[3.2.2]nonane-(4-bromo)-phenyl carbamate
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C14H17BrN2O2
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1
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| 1 |
IC50 > 3160 nM
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CP0473866
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naphthalen-2-yl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
Show/Hide
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C18H20N2O2
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1
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| 1 |
IC50 > 3160 nM
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CP0006016
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2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
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C13H17N5
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1
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| 1 |
Ki = 0.05129 nM
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CP0463875
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4-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
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C18H24N4O2
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1
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| 1 |
Ki = 0.17 nM
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CP0376399
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1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-7-(phenylmethoxy)-1Hindazole-3-carboxamide
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C25H30N4O2
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1
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| 1 |
Ki = 0.23 nM
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CP0397545
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2-(4-Methyl-piperazin-1-yl)-quinoline
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C14H17N3
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1
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| 1 |
Ki = 0.4571 nM
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CP0450378
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7-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
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C18H24N4O2
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1
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| 1 |
Ki = 0.67 nM
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CP0868562
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endo-5,5-difluoro-3-(4-methoxyphenyl)-7,9-dimethyl-8-(3-(6-(3-(3-(9-methyl-9-azabicyclo[3.3.1]nonan-3-ylcarbamoyl)-1H-indazol-1-yl)propylamino)-6-oxohexylamino)-3-oxopropyl)-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide
Show/Hide
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C47H59BF2N8O4
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1
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| 1 |
Ki = 0.9 nM
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CP0859104
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2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-(3-(4-(3-((endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-ylcarbamoyl)-1H-indazol-1-yl)butyl)thioureido)benzoic acid
Show/Hide
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C42H42N6O6S
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1
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| 1 |
Ki = 1.1 nM
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CP0430973
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6-chloro-N-methyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
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C14H18ClN5
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1
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| 1 |
Ki = 1.122 nM
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CP0860109
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1-(3-(5-(dimethylamino)naphthalene-1-sulfonamido)propyl)-N-((endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide
Show/Hide
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C32H40N6O3S
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1
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| 1 |
Ki = 1.2 nM
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CP0401982
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2-(4-methylpiperazin-1-yl)quinazoline
Show/Hide
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C13H16N4
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1
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| 1 |
Ki = 1.349 nM
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CP0447969
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2-(4-methylpiperazin-1-yl)quinolin-4-amine
Show/Hide
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C14H18N4
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1
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| 1 |
Ki = 1.445 nM
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CP0002793
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(BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide
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C18H24N4O
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1
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| 1 |
Ki = 1.45 nM
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CP0484307
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6-chloro-2-[(1-methylpiperidin-4-ylidene)methyl]-1H-benzimidazole
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C14H16ClN3
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1
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| 1 |
Ki = 1.585 nM
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CP0868526
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endo-2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-5-(3-(3-(3-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)carbamoyl)-1H-indazol-1-yl)propyl)thioureido)benzoic acid
Show/Hide
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C41H40N6O6S
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1
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| 1 |
Ki = 1.6 nM
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CP0875095
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5,5-difluoro-1,3,7,9-tetramethyl-10-(3-((4-(3-(((endo)-9-methyl-9azabicyclo[3.3.1]nonan-3-yl)carbamoyl)-1H-indazol-1-yl)butanoyl)oxy)propyl)-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide
Show/Hide
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C37H47BF2N6O3
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1
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| 1 |
Ki = 1.6 nM
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CP0453549
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3-(4-methylpiperazin-1-yl)isoquinoline
Show/Hide
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C14H17N3
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1
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| 1 |
Ki = 1.622 nM
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CP0917386
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1-(3-Aminopropyl)-N-[(3-endo)-9-methyl-9-azabicyclo-[3.3.1]-non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
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C20H29N5O
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1
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| 1 |
Ki = 1.89 nM
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CP0917542
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endo-7-(2-(7-(diethylamino)-2-oxo-2H-chromene-3-carboxamido)ethoxy)-1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide
Show/Hide
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C34H42N6O5
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1
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| 1 |
Ki = 1.9 nM
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CP0401911
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N-[(4-aminophenyl)methyl]-6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
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C20H23ClN6
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1
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| 1 |
Ki = 2.692 nM
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CP0874899
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5,5-difluoro-7,9-dimethyl-3-(2-(3-(3-((1S,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-ylcarbamoyl)-1H-indazol-1-yl)propylamino)-2-oxoethylamino)-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide
Show/Hide
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C33H41BF2N8O2
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1
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| 1 |
Ki = 2.8 nM
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CP0000082
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CAS_68647
Show/Hide
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C18H19N3O
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1
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| 1 |
Ki = 2.8 nM
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CP0336633
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6-chloro-N-(furan-3-ylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
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C18H20ClN5O
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1
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| 1 |
Ki = 2.818 nM
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CP0412881
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N-methyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
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C14H19N5
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1
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| 1 |
Ki = 2.951 nM
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CP0381178
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2-(4-Methyl-piperazin-1-yl)-quinoxaline
Show/Hide
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C13H16N4
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1
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| 1 |
Ki = 4.677 nM
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CP0479502
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N-methyl-3-(4-methylpiperazin-1-yl)isoquinolin-1-amine
Show/Hide
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C15H20N4
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1
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| 1 |
Ki = 5.888 nM
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CP0479504
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6-chloro-N,N-dimethyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
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C15H20ClN5
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1
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| 1 |
Ki = 6.607 nM
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CP0376397
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5-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
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C18H24N4O2
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1
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| 1 |
Ki = 7.3 nM
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CP0915048
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endo-1-(4-(7-(Diethylamino)-2-oxo-2H-chromene-3-carboxamido)butyl)-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide
Show/Hide
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C35H44N6O4
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1
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| 1 |
Ki = 7.3 nM
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CP0689934
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1-[2-(2-Chloro-4-methyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
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C17H20Cl2N2S
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1
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| 1 |
Ki = 7.3 nM
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CP0479505
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6-chloro-2-(4-methylpiperazin-1-yl)quinazoline
Show/Hide
|
C13H15ClN4
|
1
|
| 1 |
Ki = 7.413 nM
|
|
|
|
CP0875094
|
N-((endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1-(3-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)propyl)-1H-indazole-3-carboxamide
Show/Hide
|
C26H30N8O4
|
1
|
| 1 |
Ki = 8.7 nM
|
|
|
|
CP0891181
|
1-[2-(2-Chloro-4-methoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H20Cl2N2OS
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0429211
|
6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C13H16ClN5
|
1
|
| 1 |
Ki = 12.02 nM
|
|
|
|
CP0450853
|
3-(4-methylpiperazin-1-yl)-1H-quinoxalin-2-one
Show/Hide
|
C13H16N4O
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0457032
|
N-methyl-2-(4-methylpiperazin-1-yl)quinolin-4-amine
Show/Hide
|
C15H20N4
|
1
|
| 1 |
Ki = 13.49 nM
|
|
|
|
CP0499287
|
N-benzyl-6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C20H22ClN5
|
1
|
| 1 |
Ki = 13.8 nM
|
|
|
|
CP0376371
|
2-[[6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-yl]amino]ethanol
Show/Hide
|
C15H20ClN5O
|
1
|
| 1 |
Ki = 14.79 nM
|
|
|
|
CP0911543
|
1-[2-(2-Methoxy-4-methyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2OS
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0497910
|
6-chloro-N-methyl-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Show/Hide
|
C15H20ClN5
|
1
|
| 1 |
Ki = 18.2 nM
|
|
|
|
CP0658701
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2S
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0689935
|
1-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C16H17Cl3N2S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0450375
|
4-Methoxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
|
C19H26N4O2
|
1
|
| 1 |
Ki = 26.3 nM
|
|
|
|
CP0930877
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-[1,4]diazepane Hydrochloride
Show/Hide
|
C19H25ClN2S
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0722890
|
1-[2-(2,3-Dimethyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2S
|
1
|
| 1 |
Ki = 29 nM
|
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CP0862690
|
1-[2-(2-Methyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H21ClN2S
|
1
|
| 1 |
Ki = 32 nM
|
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|
|
CP0904235
|
1-[2-(2,4-Dimethoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2O2S
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0689936
|
1-[2-(3,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2S
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0718265
|
1-[2-(4-Chloro-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
|
C16H18Cl2N2S
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0848958
|
1-[2-(4-Methoxy-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0895089
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-4-methyl-phenyl]-piperazine Hydrochloride
Show/Hide
|
C19H25ClN2S
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0413712
|
AMI-098
Show/Hide
|
C13H16N4O
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
|
CP0848955
|
1-[2-(2-Methoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0852401
|
1-[2-(4-Fluoro-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
|
C16H18ClFN2S
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0658702
|
1-(2-p-Tolylsulfanyl-phenyl)-piperazine hydrochloride
Show/Hide
|
C17H21ClN2S
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0415289
|
1-Methyl-N-[(3-endo)-9-(phenylmethyl)-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
|
C24H28N4O
|
1
|
| 1 |
Ki = 59.3 nM
|
|
|
|
CP0882249
|
1-[2-(3-Methoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H21ClN2OS
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0891182
|
1-(2-Phenylsulfanyl-phenyl)-piperazine hydrochloride
Show/Hide
|
C16H19ClN2S
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0912456
|
1-[2-(3-Methyl-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C17H21ClN2S
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0717003
|
1-[2-(2,3-Dichloro-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C16H17Cl3N2S
|
1
|
| 1 |
Ki = 67 nM
|
|
|
|
CP0524323
|
7-Methoxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
|
C19H26N4O2
|
1
|
| 1 |
Ki = 71.1 nM
|
|
|
|
CP0488525
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-(2-phenylethyl)quinazolin-4-amine
Show/Hide
|
C21H24ClN5
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0881043
|
1-[2-(2,3-Dimethoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2O2S
|
1
|
| 1 |
Ki = 80 nM
|
|
|
|
CP0881044
|
1-[2-(3,4-Dimethoxy-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2O2S
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0912453
|
1-[2-(3,4-Dichloro-phenylsulfanyl)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C16H17Cl3N2S
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0899691
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-4-methyl-piperazine Hydrochloride
Show/Hide
|
C19H25ClN2S
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0852399
|
1-[2-(4-Trifluoromethyl-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
|
C17H18ClF3N2S
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0875089
|
endo-1-(2-(2-(2-(7-(Diethylamino)-2-oxo-2H-chromene-3-carboxamido)ethoxy)ethoxy)ethyl)-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide
Show/Hide
|
C37H48N6O6
|
1
|
| 1 |
Ki = 142 nM
|
|
|
|
CP0912420
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-5-methyl-phenyl]-piperazine Hydrochloride
Show/Hide
|
C19H25ClN2S
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0921330
|
endo-7-(3-(7-(Diethylamino)-2-oxo-2H-chromene-3-carboxamido)propoxy)-1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide
Show/Hide
|
C35H44N6O5
|
1
|
| 1 |
Ki = 157 nM
|
|
|
|
CP0866034
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-6-methyl-phenyl]-piperazine Hydrochloride
Show/Hide
|
C19H25ClN2S
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0381149
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-propan-2-ylquinazolin-4-amine
Show/Hide
|
C16H22ClN5
|
1
|
| 1 |
Ki = 165.96 nM
|
|
|
|
CP0667134
|
1-[2-(4-Methoxy-phenylsulfanyl)-5-methyl-phenyl]-piperazine hydrochloride
Show/Hide
|
C18H23ClN2OS
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0918112
|
1-(3-(7-(Diethylamino)-2-oxo-2H-chromene-3-carboxamido)propyl)-N-((3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide
Show/Hide
|
C34H42N6O4
|
1
|
| 1 |
Ki = 199 nM
|
|
|
|
CP0479501
|
2-(4-methylpiperazin-1-yl)quinolin-5-amine
Show/Hide
|
C14H18N4
|
1
|
| 1 |
Ki = 204.17 nM
|
|
|
|
CP0922091
|
2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-(3-(2-(2-(2-(1-methyl-3-((endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-ylcarbamoyl)-1H-indazol-7-yloxy)ethoxy)ethoxy)ethyl)thioureido)benzoic acid
Show/Hide
|
C45H48N6O9S
|
1
|
| 1 |
Ki = 208 nM
|
|
|
|
CP0544240
|
3-(4-methylpiperazin-1-yl)isoquinolin-1-amine
Show/Hide
|
C14H18N4
|
1
|
| 1 |
Ki = 218.78 nM
|
|
|
|
CP0384434
|
6-Methoxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
|
C19H26N4O2
|
1
|
| 1 |
Ki = 237 nM
|
|
|
|
CP0412519
|
6-chloro-2-(4-methylpiperazin-1-yl)quinoline
Show/Hide
|
C14H16ClN3
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0914964
|
1-(5-Methyl-2-p-tolylsulfanyl-phenyl)-piperazine hydrochloride
Show/Hide
|
C18H23ClN2S
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0870586
|
1-[2-(2,4-Dimethyl-phenoxy)-phenyl]-piperazine Hydrochloride
Show/Hide
|
C18H23ClN2O
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0450376
|
6-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
|
C18H24N4O2
|
1
|
| 1 |
Ki = 279 nM
|
|
|
|
CP0391907
|
3-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C13H13ClN2O
|
1
|
| 1 |
Ki = 303 nM
|
|
|
|
CP0852397
|
1-(5-Methyl-2-phenylsulfanyl-phenyl)-piperazine hydrochloride
Show/Hide
|
C17H21ClN2S
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0485068
|
4-((naphthalen-2-yloxy)methyl)piperidine
Show/Hide
|
C16H19NO
|
1
|
| 1 |
Ki = 311 nM
|
|
|
|
CP0497909
|
2-(4-methylpiperazin-1-yl)quinolin-8-amine
Show/Hide
|
C14H18N4
|
1
|
| 1 |
Ki = 331.13 nM
|
|
|
|
CP0463876
|
1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-4-(phenylmethoxy)-1Hindazole-3-carboxamide
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
Ki = 375 nM
|
|
|
|
CP0399682
|
7-(piperidin-4-ylmethoxy)-2-naphthonitrile
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
Ki = 404 nM
|
|
|
|
CP0453976
|
3-(4-methylpiperazin-1-yl)quinoline
Show/Hide
|
C14H17N3
|
1
|
| 1 |
Ki = 407.38 nM
|
|
|
|
CP0456120
|
3-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
Ki = 420 nM
|
|
|
|
CP0852396
|
1-[2-(4-Fluoro-phenylsulfanyl)-5-methyl-phenyl]-piperazine hydrochloride
Show/Hide
|
C17H20ClFN2S
|
1
|
| 1 |
Ki = 440 nM
|
|
|
|
CP0852398
|
1-[2-(4-tert-Butyl-phenylsulfanyl)-phenyl]-piperazine hydrochloride
Show/Hide
|
C20H27ClN2S
|
1
|
| 1 |
Ki = 450 nM
|
|
|
|
CP0412883
|
6-chloro-2-[3-(dimethylamino)azetidin-1-yl]-N-methylquinazolin-4-amine
Show/Hide
|
C14H18ClN5
|
1
|
| 1 |
Ki = 467.74 nM
|
|
|
|
CP0882250
|
1-[2-(4-Chloro-phenylsulfanyl)-5-methyl-phenyl]-piperazine hydrochloride
Show/Hide
|
C17H20Cl2N2S
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0479503
|
1-methyl-4-naphthalen-2-ylpiperazine
Show/Hide
|
C15H18N2
|
1
|
| 1 |
Ki = 537.03 nM
|
|
|
|
CP0401983
|
6-chloro-2-(4-methylpiperazin-1-yl)-3H-quinazolin-4-one
Show/Hide
|
C13H15ClN4O
|
1
|
| 1 |
Ki = 575.44 nM
|
|
|
|
CP0870587
|
1-[2-(2,4-Dimethyl-phenylsulfanyl)-3-methyl-phenyl]-piperazine
Show/Hide
|
C19H25ClN2S
|
1
|
| 1 |
Ki = 670 nM
|
|
|
|
CP0391908
|
3-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
Show/Hide
|
C13H13FN2O
|
1
|
| 1 |
Ki = 703 nM
|
|
|
|
CP0450377
|
1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-6-(phenylmethoxy)-1Hindazole-3-carboxamide
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
Ki = 749 nM
|
|
|
|
CP0452486
|
2-(3-phenylpropyl)guanidine
Show/Hide
|
C10H15N3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0460151
|
3-(4-chlorophenyl)pyrrolidine
Show/Hide
|
C10H12ClN
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0494232
|
acridin-3-amine
Show/Hide
|
C13H10N2
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0259827
|
4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
Show/Hide
|
C15H19N5
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0502535
|
5-(cyclohexylmethyl)-1H-imidazole
Show/Hide
|
C10H16N2
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0917541
|
endo-7-(2-(2-(2-(7-(Diethylamino)-2-oxo-2H-chromene-3-carboxamido)ethoxy)ethoxy)ethoxy)-1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide
Show/Hide
|
C38H50N6O7
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0401987
|
2-[(3S)-3-aminopyrrolidin-1-yl]-6-chloro-N-methylquinazolin-4-amine
Show/Hide
|
C13H16ClN5
|
1
|
| 1 |
Ki = 2344.23 nM
|
|
|
|
CP0030044
|
(+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene
Show/Hide
|
C17H19N3
|
1
|
| 1 |
Ki = 2900 nM
|
|
|
|
CP0376398
|
1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-5-(phenylmethoxy)-1Hindazole-3-carboxamide
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
Ki = 3029 nM
|
|
|
|
CP0412882
|
2-(1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl)-6-chloro-N-methylquinazolin-4-amine
Show/Hide
|
C16H20ClN5
|
1
|
| 1 |
Ki = 3548.13 nM
|
|
|
|
CP0463877
|
5-Methoxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Show/Hide
|
C19H26N4O2
|
1
|
| 1 |
Ki = 5306 nM
|
|
|
|
CP0868563
|
endo-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-(3-(2-(2-(2-(3-((9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)carbamoyl)-1H-indazol-1-yl)ethoxy)ethoxy)ethyl)thioureido)benzoic acid
Show/Hide
|
C44H46N6O8S
|
1
|
| 1 |
Ki = 6300 nM
|
|
|
|
CP0384765
|
(+/-)-4-(2-methoxy-1-(naphthalen-2-yloxy)ethyl)piperidine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0372923
|
2-[3-[(2S,5S)-5-[(6-bromo-1H-indol-3-yl)methyl]-3,6-dioxopiperazin-2-yl]propyl]guanidine
Show/Hide
|
C17H21BrN6O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0845072
|
(cyclo[(6-bromo-8-entryptophan)arginine])
Show/Hide
|
C17H19BrN6O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0042717
|
(buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
Show/Hide
|
C21H31N5O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391901
|
3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C13H14ClN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391904
|
3-(4-methylphenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C14H17N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391906
|
3-(4-fluorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
Show/Hide
|
C13H14FN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0479569
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6-chloro-4-N-methyl-2-N-[2-(1-methylpyrrolidin-3-yl)ethyl]quinazoline-2,4-diamine
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C16H22ClN5
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1
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| 1 |
Ki = 11748.98 nM
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CP0376370
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6-chloro-N-(cyclohexylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
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C20H28ClN5
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1
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| 1 |
Ki = 16595.87 nM
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CP0006941
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(14-dimethylaminomethyl-6H,13H-pyrazino[1,2-a;4,5-a']diindol-7-ylmethyl)-dimethyl-amine
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C24H28N4
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1
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| 1 |
Ki > 100000 nM
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CP0633846
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{[20-({dimethyl[(4-nitrophenyl)methyl]azaniumyl}methyl)-3,13-diazapentacyclo[11.7.0.0^{3,11}.0^{4,9}.0^{14,19}]icosa-1(20),4,6,8,10,14(19),15,17-octaen-10-yl]methyl}dimethyl[(4-nitrophenyl)methyl]azanium dibromide
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C38H40Br2N6O4
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1
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| 1 |
Ki > 100000 nM
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CP0633847
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(1S,11S,13S,17R,18R,20R,27S,29R,30R,31S,35E)-14,26-bis[(3,4-dimethoxyphenyl)methyl]-35-(2-hydroxyethylidene)-19-phenyl-21-oxa-8,14,19,26-tetraazadecacyclo[24.5.2.2^{11,14}.0^{1,27}.0^{2,7}.0^{8,31}.0^{10,18}.0^{13,17}.0^{20,30}.0^{24,29}]pentatriaconta-2,4,6,9,23-pentaene-14,26-diium dichloride
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C56H64Cl2N4O6
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1
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| 1 |
Ki = 100000 nM
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CP0633851
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(1S,11S,13S,18R,20R,27S,29R,30R,31S,35E)-35-(2-hydroxyethylidene)-14,26-bis[(4-nitrophenyl)methyl]-19-phenyl-21-oxa-8,14,19,26-tetraazadecacyclo[24.5.2.2^{11,14}.0^{1,27}.0^{2,7}.0^{8,31}.0^{10,18}.0^{13,17}.0^{20,30}.0^{24,29}]pentatriaconta-2,4,6,9,23-pentaene-14,26-diium dibromide
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C52H54Br2N6O6
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1
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| 1 |
Ki = 100000 nM
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