Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_40796-97-2
    Show/Hide
 PubChem ID
SID: 12012948
Canonical SMILES
CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1cc(Cl)cc(Cl)c1
    Show/Hide
Compound Formula C15H17Cl2NO2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 3A
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
5HT3 receptor
Uniprot ID
P46098
Gene Name
HTR3A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6.9 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
2
Ki = 2.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.9 nM
2 IC50 = 6.7 nM
3 IC50 = 9.4 nM
4 IC50 = 10 nM
5 Ki = 3.9 nM
6 Ki = 4.7 nM
7 Ki = 6.6 nM