Brief Information of the Cell Line and Protein
Cell Line ID: CL000013 , Sf9
Synonyms
SF9
sf9
SF-9
Sf-9
sf-9
Sf 9
Spodoptera frugiperda clone 9
Sf clone 9
IPLB-Sf-9AE
IPLB-SF-9AE
IPLB-SF-9
IPLB-Sf-9
IPLB-Sf9
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0549
Protein ID: PT01946 , Histone deacetylase 9
Gene Name HDAC9
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q9UKV0
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000013  Protein ID: PT01946
 
Compound ID Compound Name Compound Formula
CP0008777
JNJ-26481585
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C21H26N6O2
 1
1
IC50 = 6.7 nM
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CP0014274
N-(1-benzylpyrrolidin-3-yl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide
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C21H19F3N4O2
 1
1
IC50 = 48 nM
   TI
   LI
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   TS
CP0514799
4-[(2-chlorophenothiazin-10-yl)methyl]-N-hydroxybenzamide
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C20H15ClN2O2S
 1
1
IC50 = 350 nM
   TI
   LI
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   TS
CP0311861
4-[(2-fluoroacridin-9-yl)amino]-N-hydroxybenzamide
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C20H14FN3O2
 1
1
IC50 = 520 nM
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CP0003676
N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide
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C23H24N8O4S
 2
1
IC50 = 554 nM
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2
IC50 = 639 nM
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CP0014957
4-(acridin-9-ylamino)-N-hydroxybenzamide
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C20H15N3O2
 1
1
IC50 = 570 nM
   TI
   LI
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   TS
CP0317632
10-[[4-(hydroxycarbamoyl)phenyl]methyl]phenothiazine-2-carboxamide
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C21H17N3O3S
 1
1
IC50 = 590 nM
   TI
   LI
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   TS
CP0540403
N-hydroxy-4-[(2-methylsulfanyl-5-oxophenothiazin-10-yl)methyl]benzamide
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C21H18N2O3S2
 1
1
IC50 = 720 nM
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   TS
CP0565304
10-[[4-(hydroxycarbamoyl)phenyl]methyl]-N-pyridin-2-ylphenothiazine-2-carboxamide
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C26H20N4O3S
 1
1
IC50 = 730 nM
   TI
   LI
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   TS
CP0013013
N-tert-butyl-2-[3-[6-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-1H-benzimidazol-2-yl]phenyl]imidazo[1,2-a]pyridin-3-amine
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C27H22F3N7O
 1
1
IC50 = 818 nM
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CP0568061
N-(5-bromopyridin-2-yl)-10-[[4-(hydroxycarbamoyl)phenyl]methyl]phenothiazine-2-carboxamide
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C26H19BrN4O3S
 1
1
IC50 = 850 nM
   TI
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   TS
CP0003580
Faridak
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C21H23N3O2
 3
1
IC50 = 887.8 nM
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2
IC50 = 2680 nM
   TI
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3
IC50 > 20000 nM
   TI
   LI
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   TS
CP0548340
10-[[4-(hydroxycarbamoyl)phenyl]methyl]-N-(5-methylpyridin-2-yl)phenothiazine-2-carboxamide
   Show/Hide
C27H22N4O3S
 1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
CP0344801
N-hydroxy-4-[(2-phenylmethoxyacridin-9-yl)amino]benzamide
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C27H21N3O3
 1
1
IC50 = 1250 nM
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   TS
CP0013085
N-hydroxy-7-[2-[3-(hydroxymethyl)phenyl]-6-morpholin-4-ylpurin-9-yl]heptanamide
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C23H30N6O4
 1
1
IC50 = 1282 nM
   TI
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CP0003577
N-(2-amino-4-fluorophenyl)-3-[3-(tert-butylamino)imidazo[1,2-a]pyridin-2-yl]benzamide
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C24H24FN5O
 1
1
IC50 = 1300 nM
   TI
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CP0557703
4-[(2-chloro-5-oxophenothiazin-10-yl)methyl]-N-hydroxybenzamide
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C20H15ClN2O3S
 1
1
IC50 = 1960 nM
   TI
   LI
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   TS
CP0012152
N-tert-butyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]imidazo[1,2-a]pyridin-3-amine
   Show/Hide
C20H18F3N5O
 1
1
IC50 = 2311 nM
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CP0548395
N-hydroxy-4-[[2-(trifluoromethyl)phenothiazin-10-yl]methyl]benzamide
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C21H15F3N2O2S
 1
1
IC50 = 2580 nM
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CP0514803
N-hydroxy-4-[(2-methylsulfanylphenothiazin-10-yl)methyl]benzamide
   Show/Hide
C21H18N2O2S2
 1
1
IC50 = 3260 nM
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CP0514798
N-hydroxy-4-[[5-oxo-2-(trifluoromethyl)phenothiazin-10-yl]methyl]benzamide
   Show/Hide
C21H15F3N2O3S
 1
1
IC50 = 3820 nM
   TI
   LI
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CP0548341
10-[[4-(hydroxycarbamoyl)phenyl]methyl]-5-oxophenothiazine-2-carboxamide
   Show/Hide
C21H17N3O4S
 1
1
IC50 = 4200 nM
   TI
   LI
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CP0514800
N-hydroxy-4-[[2-[(E)-N-hydroxy-C-methylcarbonimidoyl]phenothiazin-10-yl]methyl]benzamide
   Show/Hide
C22H19N3O3S
 1
1
IC50 = 4340 nM
   TI
   LI
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   TS
CP0311798
N-hydroxy-4-[(1,2,3-trimethoxyacridin-9-yl)amino]benzamide
   Show/Hide
C23H21N3O5
 1
1
IC50 = 4950 nM
   TI
   LI
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CP0013440
4-[(2-bromoacridin-9-yl)amino]-N-hydroxybenzamide
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C20H14BrN3O2
 1
1
IC50 = 5510 nM
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CP0528389
2-[4-(acridin-9-ylamino)phenyl]-N-hydroxyacetamide
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C21H17N3O2
 1
1
IC50 = 6420 nM
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CP0554587
N-hydroxy-4-[(2-methoxy-5-oxophenothiazin-10-yl)methyl]benzamide
   Show/Hide
C21H18N2O4S
 1
1
IC50 = 6560 nM
   TI
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   TS
CP0514802
10-[[4-[(E)-3-(hydroxyamino)-3-oxoprop-1-enyl]phenyl]methyl]phenothiazine-2-carboxamide
   Show/Hide
C23H19N3O3S
 1
1
IC50 = 8270 nM
   TI
   LI
   LO
   TS
CP0001837
N'-hydroxy-N-[3-[4-(5,6,7-trimethoxyindol-1-yl)butoxy]phenyl]octanediamide
   Show/Hide
C29H39N3O7
 1
1
IC50 > 10000 nM
   TI
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   LO
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CP0001838
N-[4-[2-(5,6-dimethoxyindol-1-yl)ethoxy]phenyl]-N'-hydroxyoctanediamide
   Show/Hide
C26H33N3O6
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0003832
N'-hydroxy-N-phenyloctanediamide
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C14H20N2O3
 3
1
IC50 > 10000 nM
   TI
   LI
   LO
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2
IC50 = 15830 nM
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3
IC50 = 32260 nM
   TI
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CP0010901
N'-hydroxy-N-[3-[2-(5,6,7-trimethoxyindol-1-yl)ethoxy]phenyl]octanediamide
   Show/Hide
C27H35N3O7
 1
1
IC50 > 10000 nM
   TI
   LI
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   TS
CP0013329
N'-hydroxy-N-[4-[2-(5-methoxyindol-1-yl)ethoxy]phenyl]octanediamide
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C25H31N3O5
 1
1
IC50 > 10000 nM
   TI
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CP0007860
7-[2-(6-aminopyridin-3-yl)-6-morpholin-4-ylpurin-9-yl]-N-hydroxyheptanamide
   Show/Hide
C21H28N8O3
 1
1
IC50 > 10000 nM
   TI
   LI
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   TS
CP0013233
7-[2-(2-aminopyrimidin-5-yl)-4-morpholin-4-ylpyrrolo[2,3-d]pyrimidin-7-yl]-N-hydroxyheptanamide
   Show/Hide
C21H28N8O3
 1
1
IC50 > 10000 nM
   TI
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CP0013235
(E)-3-[2-butyl-1-[2-(diethylamino)ethyl]benzimidazol-5-yl]-N-hydroxyprop-2-enamide
   Show/Hide
C20H32Cl2N4O2
 1
1
IC50 > 10000 nM
   TI
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CP0478984
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-hydroxy-4-oxochromen-7-yl]oxy-N-hydroxyhexanamide;hydrochloride
   Show/Hide
C25H31ClN2O7
 1
1
IC50 > 10000 nM
   TI
   LI
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   TS
CP0013240
N-tert-butyl-2-[3-[6-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-1H-benzimidazol-2-yl]phenyl]imidazo[1,2-a]pyrazin-3-amine
   Show/Hide
C26H21F3N8O
 1
1
IC50 > 10000 nM
   TI
   LI
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   TS
CP0014885
N'-hydroxy-2-(3-imidazo[1,2-a]pyridin-2-ylphenyl)-3H-benzimidazole-5-carboximidamide
   Show/Hide
C21H16N6O
 1
1
IC50 > 10000 nM
   TI
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CP0012571
(4Z,7S,10S)-7-(4-aminobutyl)-4-ethylidene-10-[(E)-4-(heptyldisulfanyl)but-1-enyl]-9-oxa-16-thia-3,6,13,18-tetrazabicyclo[13.2.1]octadeca-1(17),15(18)-diene-2,5,8,12-tetrone
   Show/Hide
C29H45N5O5S3
 1
1
IC50 > 10000 nM
   TI
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CP0015005
S-[(E)-4-[(4Z,7S,10S)-4-ethylidene-2,5,8,12-tetraoxo-7-propan-2-yl-9-oxa-16-thia-3,6,13,18-tetrazabicyclo[13.2.1]octadeca-1(17),15(18)-dien-10-yl]but-3-enyl] octanethioate
   Show/Hide
C29H42N4O6S2
 1
1
IC50 > 10000 nM
   TI
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CP0528390
3-(acridin-9-ylamino)-N-hydroxybenzamide
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C20H15N3O2
 1
1
IC50 = 12180 nM
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CP0514885
N-hydroxy-4-(quinolin-4-ylamino)benzamide
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C16H13N3O2
 1
1
IC50 = 13230 nM
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CP0444962
5-cyclopropyl-N-[(1S)-1-[4-(hydroxycarbamoyl)phenyl]ethyl]-2-(5-phenyl-1,3-thiazol-2-yl)-1,3-thiazole-4-carboxamide
   Show/Hide
C25H22N4O3S2
 1
1
IC50 > 20000 nM
   TI
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CP0514801
N-hydroxy-4-[(5-oxophenothiazin-10-yl)methyl]benzamide
   Show/Hide
C20H16N2O3S
 1
1
IC50 = 27570 nM
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   TS
CP0165687
3-[4-(acridin-9-ylamino)phenyl]-N-hydroxypropanamide
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C22H19N3O2
 1
1
IC50 = 28960 nM
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CP0563662
N-hydroxy-4-[(2-methoxyphenothiazin-10-yl)methyl]benzamide
   Show/Hide
C21H18N2O3S
 1
1
IC50 = 29700 nM
   TI
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   TS
CP0564220
N-hydroxy-4-[[2-(trifluoromethoxy)acridin-9-yl]amino]benzamide
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C21H14F3N3O3
 1
1
IC50 = 31100 nM
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CP0447502
(1R,5S)-N-[2-amino-5-(4-fluorophenyl)phenyl]-8-oxabicyclo[3.2.1]octane-3-carboxamide
   Show/Hide
C20H21FN2O2
 1
1
IC50 > 33330 nM
   TI
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   TS
CP0543376
N-hydroxy-4-(phenothiazin-10-ylmethyl)benzamide
   Show/Hide
C20H16N2O2S
 1
1
IC50 = 36470 nM
   TI
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CP0311797
N-hydroxy-4-(1,2,3,4-tetrahydroacridin-9-ylamino)benzamide
   Show/Hide
C20H19N3O2
 1
1
IC50 > 40000 nM
   TI
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CP0552771
4-[(7-chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino]-N-hydroxybenzamide
   Show/Hide
C20H15ClN4O3
 1
1
IC50 > 40000 nM
   TI
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CP0514804
N-hydroxy-4-[[2-[(E)-N-hydroxy-C-methylcarbonimidoyl]-5-oxophenothiazin-10-yl]methyl]benzamide
   Show/Hide
C22H19N3O4S
 1
1
IC50 > 40000 nM
   TI
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   TS
CP0004262
N-hydroxy-2-[methyl-[(9-methyl-6-morpholin-4-yl-2-pyridin-4-ylpurin-8-yl)methyl]amino]pyrimidine-5-carboxamide
   Show/Hide
C22H24N10O3
 1
1
IC50 > 1000 nM
   TI
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   TS
CP0004673
N-hydroxy-2-[[2-(4-methoxyphenyl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl-methylamino]pyrimidine-5-carboxamide
   Show/Hide
C24H27N9O4
 1
1
IC50 > 1000 nM
   TI
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   TS
CP0005544
2-[[2-(4-aminophenyl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl-methylamino]-N-hydroxypyrimidine-5-carboxamide
   Show/Hide
C23H26N10O3
 1
1
IC50 > 1000 nM
   TI
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   TS
CP0005903
N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl-methylamino]pyrimidine-5-carboxamide
   Show/Hide
C23H26N10O4
 1
1
IC50 > 1000 nM
   TI
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   TS
CP0010223
2-[[2-(2-aminopyrimidin-5-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl-methylamino]-N-hydroxypyrimidine-5-carboxamide
   Show/Hide
C21H24N12O3
 1
1
IC50 > 1000 nM
   TI
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CP0004988
pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
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C21H20N4O3
 1
1
IC50 > 1000 nM
   TI
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CP0005479
CHEBI:46024
   Show/Hide
C17H22N2O3
 1
1
IC50 > 1000 nM
   TI
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   TS
CP0417643
4-tert-butyl-N-[4-(hydroxycarbamoyl)phenyl]benzamide
   Show/Hide
C18H20N2O3
 1
1
IC50 > 1000 nM
   TI
   LI
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   TS
CP0421417
2,3,4,5,6-pentafluoro-N-[[4-(hydroxycarbamoyl)phenyl]methyl]benzamide
   Show/Hide
C15H9F5N2O3
 1
1
IC50 > 1000 nM
   TI
   LI
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   TS
CP0542777
4-[[cyclopropyl-(2,3,4,5-tetrafluorophenyl)sulfonylamino]methyl]-N-hydroxybenzamide
   Show/Hide
C17H14F4N2O4S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0545520
N-hydroxy-4-[[propan-2-yl-(2,3,4,5-tetrafluorophenyl)sulfonylamino]methyl]benzamide
   Show/Hide
C17H16F4N2O4S
 1
1
IC50 > 5000 nM
   TI
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   TS