General Information of the Compound
| Compound ID |
CP0012152
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| Compound Name |
N-tert-butyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]imidazo[1,2-a]pyridin-3-amine
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| Formula |
C20H18F3N5O
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| Molecular Weight |
401.392
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| Canonical SMILES |
CC(C)(C)Nc1c(nc2ccccn12)-c1ccc(cc1)-c1noc(n1)C(F)(F)F
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| InChI |
InChI=1S/C20H18F3N5O/c1-19(2,3)26-17-15(24-14-6-4-5-11-28(14)17)12-7-9-13(10-8-12)16-25-18(29-27-16)20(21,22)23/h4-11,26H,1-3H3
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| InChIKey |
QCKNTQLUQMEQRQ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT00835, Histone deacetylase 2
Protein ID: PT00994, Histone deacetylase 4
Protein ID: PT00996, Histone deacetylase 5
Protein ID: PT01807, Histone deacetylase 7
Protein ID: PT01946, Histone deacetylase 9