General Information of the Compound
| Compound ID |
CP0565304
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| Compound Name |
10-[[4-(hydroxycarbamoyl)phenyl]methyl]-N-pyridin-2-ylphenothiazine-2-carboxamide
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| Formula |
C26H20N4O3S
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| Molecular Weight |
468.538
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| Canonical SMILES |
ONC(=O)c1ccc(CN2c3ccccc3Sc3ccc(cc23)C(=O)Nc2ccccn2)cc1
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| InChI |
InChI=1S/C26H20N4O3S/c31-25(28-24-7-3-4-14-27-24)19-12-13-23-21(15-19)30(20-5-1-2-6-22(20)34-23)16-17-8-10-18(11-9-17)26(32)29-33/h1-15,33H,16H2,(H,29,32)(H,27,28,31)
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| InChIKey |
XIGDWHNBRJVSHI-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00994, Histone deacetylase 4
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01807, Histone deacetylase 7
Protein ID: PT01946, Histone deacetylase 9