General Information of the Compound
| Compound ID |
CP0568061
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| Compound Name |
N-(5-bromopyridin-2-yl)-10-[[4-(hydroxycarbamoyl)phenyl]methyl]phenothiazine-2-carboxamide
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| Formula |
C26H19BrN4O3S
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| Molecular Weight |
547.434
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| Canonical SMILES |
ONC(=O)c1ccc(CN2c3ccccc3Sc3ccc(cc23)C(=O)Nc2ccc(Br)cn2)cc1
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| InChI |
InChI=1S/C26H19BrN4O3S/c27-19-10-12-24(28-14-19)29-25(32)18-9-11-23-21(13-18)31(20-3-1-2-4-22(20)35-23)15-16-5-7-17(8-6-16)26(33)30-34/h1-14,34H,15H2,(H,30,33)(H,28,29,32)
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| InChIKey |
IJBHQQMTDZNJTA-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00994, Histone deacetylase 4
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01807, Histone deacetylase 7
Protein ID: PT01946, Histone deacetylase 9