Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT01366 , D(3) dopamine receptor
Gene Name DRD3
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P19020
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT01366
 
Compound ID Compound Name Compound Formula
CP0339664
CHEBI:64217
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C21H26ClN3O2
 1
1
Ki = 0.16 nM
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CP0439590
N-[(3S)-1-(9-bicyclo[3.3.1]nonanyl)pyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide
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C22H32ClN3O2
 1
1
Ki = 0.24 nM
   TI
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CP0430313
4-Amino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide
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C19H22ClN3O2
 1
1
Ki = 0.58 nM
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CP0401203
5-Chloro-N-((S)-1-cycloheptyl-pyrrolidin-3-yl)-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide
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C23H32ClN3O3
 1
1
Ki = 1.5 nM
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CP0453461
N-[(3S)-1-(2-adamantyl)pyrrolidin-3-yl]-5-chloro-4-(cyclopropanecarbonylamino)-2-methoxybenzamide
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C26H34ClN3O3
 1
1
Ki = 1.7 nM
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CP0418846
4-Amino-N-((R)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide
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C19H22ClN3O2
 1
1
Ki = 1.9 nM
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CP0455425
N-[(3S)-1-(9-bicyclo[3.3.1]nonanyl)pyrrolidin-3-yl]-5-chloro-4-(cyclopropanecarbonylamino)-2-methoxybenzamide
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C25H34ClN3O3
 1
1
Ki = 2.2 nM
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CP0420757
5-Chloro-N-((S)-1-cyclohexylmethyl-pyrrolidin-3-yl)-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide
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C23H32ClN3O3
 1
1
Ki = 3.7 nM
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CP0402468
5-Chloro-N-((S)-1-cyclohexyl-pyrrolidin-3-yl)-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide
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C22H30ClN3O3
 1
1
Ki = 4.4 nM
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CP0494189
4-Acryloylamino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide
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C22H24ClN3O3
 1
1
Ki = 4.7 nM
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CP0436775
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-[(2,2,2-trifluoroacetyl)amino]benzamide
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C21H21ClF3N3O3
 1
1
Ki = 5.1 nM
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CP0509166
N-propyl-N-(2-thiophen-2-ylethyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C21H26N2S
 1
1
Ki = 5.5 nM
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CP0420813
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(propanoylamino)benzamide
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C22H26ClN3O3
 1
1
Ki = 5.9 nM
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CP0008601
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
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C21H23ClFNO2
 1
1
Ki = 6.4 nM
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CP0392682
N-[3-(2-methoxyphenyl)propyl]-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C25H32N2O
 1
1
Ki = 10 nM
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CP0264289
2-Dipropylamino-indan-5-ol
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C15H23NO
 1
1
Ki = 14 nM
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CP0432399
(5,6-Dimethoxy-indan-2-yl)-propyl-(2-thiophen-3-yl-ethyl)-amine
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C20H27NO2S
 1
1
Ki = 14 nM
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CP0480937
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(2-methylpropanoylamino)benzamide
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C23H28ClN3O3
 1
1
Ki = 15 nM
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CP0378469
(8R)-N-(2-methylpropyl)-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C19H28N2
 1
1
Ki = 18 nM
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CP0467378
N-(2-phenylethyl)-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C23H28N2
 1
1
Ki = 18 nM
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CP0374866
(8R)-8-[3-phenylpropyl(propyl)amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C25H30N2O
 1
1
Ki = 19 nM
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CP0419374
N-[3-(3-chlorophenoxy)propyl]-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C24H29ClN2O
 1
1
Ki = 20 nM
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CP0045414
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclopropanecarbonylamino)-2-methoxybenzamide
   Show/Hide
C23H26ClN3O3
 1
1
Ki = 21 nM
   TI
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CP0216619
(8S)-N,N-dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C18H26N2
 1
1
Ki = 22 nM
   TI
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CP0440199
N-[2-(4-bromophenyl)ethyl]-5,6-dimethoxy-N-propyl-2,3-dihydro-1H-inden-2-amine
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C22H28BrNO2
 1
1
Ki = 22 nM
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CP0402279
(5,6-Dimethoxy-indan-2-yl)-(3-phenyl-propyl)-propyl-amine
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C23H31NO2
 1
1
Ki = 23 nM
   TI
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CP0378588
4,4-Dimethyl-1-{4-[propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amino]-butyl}-piperidine-2,6-dione
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C26H37N3O2
 1
1
Ki = 29 nM
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CP0502453
(5,6-Dimethoxy-indan-2-yl)-[2-(3,4-dimethoxy-phenyl)-ethyl]-propyl-amine
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C24H33NO4
 1
1
Ki = 29 nM
   TI
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CP0056626
(8R)-N,N-dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C18H26N2
 1
1
Ki = 30 nM
   TI
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CP0464581
(5,6-Dimethoxy-indan-2-yl)-[2-(3-fluoro-phenyl)-ethyl]-propyl-amine
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C22H28FNO2
 1
1
Ki = 30 nM
   TI
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CP0089986
STEPHOLIDINE
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C19H21NO4
 1
1
Ki = 30 nM
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CP0288601
(5,6-Dimethoxy-indan-2-yl)-dipropyl-amine
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C17H27NO2
 1
1
Ki = 31 nM
   TI
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CP0453746
(5,6-Dimethoxy-indan-2-yl)-phenethyl-propyl-amine
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C22H29NO2
 1
1
Ki = 32 nM
   TI
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CP0472164
5-Chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-N-((S)-1-phenethyl-pyrrolidin-3-yl)-benzamide
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C24H28ClN3O3
 1
1
Ki = 33 nM
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CP0444095
(5,6-Dimethoxy-indan-2-yl)-propyl-[2-(4-trifluoromethyl-phenyl)-ethyl]-amine
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C23H28F3NO2
 1
1
Ki = 34 nM
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CP0496697
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclobutanecarbonylamino)-2-methoxybenzamide
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C24H28ClN3O3
 1
1
Ki = 36 nM
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CP0258010
(+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
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C18H26N2
 1
1
Ki = 37 nM
   TI
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CP0381060
(5,6-Dimethoxy-indan-2-yl)-[2-(4-methoxy-phenyl)-ethyl]-propyl-amine
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C23H31NO3
 1
1
Ki = 39 nM
   TI
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CP0378553
8-[(3-Phenyl-propyl)-propyl-amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C25H30N2O
 1
1
Ki = 42 nM
   TI
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CP0231107
(R)-2-Dipropylamino-indan-4-ol
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C15H23NO
 1
1
Ki = 42 nM
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CP0383519
4-{2-[(5,6-Dimethoxy-indan-2-yl)-propyl-amino]-ethyl}-benzamide
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C23H30N2O3
 1
1
Ki = 42 nM
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CP0428133
Benzyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
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C22H26N2
 1
1
Ki = 43 nM
   TI
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CP0192898
(4-Methoxy-indan-2-yl)-dipropyl-amine
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C16H25NO
 1
1
Ki = 45 nM
   TI
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CP0406263
N-[2-(3-aminophenyl)ethyl]-5,6-dimethoxy-N-propyl-2,3-dihydro-1H-inden-2-amine
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C22H30N2O2
 1
1
Ki = 45 nM
   TI
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CP0424195
8-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C22H26N2OS
 1
1
Ki = 48 nM
   TI
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CP0381324
N-(cyclopropylmethyl)-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C19H26N2
 1
1
Ki = 50 nM
   TI
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CP0276816
(R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C19H26N2O
 1
1
Ki = 51 nM
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CP0453454
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclopentanecarbonylamino)-2-methoxybenzamide
   Show/Hide
C25H30ClN3O3
 1
1
Ki = 55 nM
   TI
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CP0405581
N-[(3R)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclopropanecarbonylamino)-2-methoxybenzamide
   Show/Hide
C23H26ClN3O3
 1
1
Ki = 60 nM
   TI
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CP0497437
8-Dipropylamino-4-fluoro-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C19H25FN2O
 1
1
Ki = 65 nM
   TI
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CP0409491
(5,6-Dimethoxy-indan-2-yl)-ethyl-propyl-amine
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C16H25NO2
 1
1
Ki = 65 nM
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CP0052478
(+/-)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C19H26N2O
 1
1
Ki = 70 nM
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CP0428161
Allyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
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C18H24N2
 1
1
Ki = 77 nM
   TI
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CP0501734
(5,6-Dimethoxy-indan-2-yl)-propyl-(2-thiophen-2-yl-ethyl)-amine
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C20H27NO2S
 1
1
Ki = 78 nM
   TI
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CP0392154
8-(Phenethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C24H28N2O
 1
1
Ki = 81 nM
   TI
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CP0378377
8-{[3-(2-Methoxy-phenyl)-propyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C26H32N2O2
 1
1
Ki = 84 nM
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CP0444093
(5-Methoxy-indan-2-yl)-dipropyl-amine
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C16H25NO
 1
1
Ki = 84 nM
   TI
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CP0416467
(8R)-8-[2-methylpropyl(propyl)amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
   Show/Hide
C20H28N2O
 1
1
Ki = 100 nM
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CP0401594
N-[(3R)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclobutanecarbonylamino)-2-methoxybenzamide
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C24H28ClN3O3
 1
1
Ki = 100 nM
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CP0405371
N-methyl-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C16H22N2
 1
1
Ki = 113 nM
   TI
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CP0382288
N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C15H20N2
 1
1
Ki = 115 nM
   TI
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CP0401280
8-(Benzyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C23H26N2O
 1
1
Ki = 115 nM
   TI
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CP0425117
8-(Allyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C19H24N2O
 1
1
Ki = 130 nM
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CP0216553
N,N-dipropyl-1-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
   Show/Hide
C20H27F3N2
 1
1
Ki = 134 nM
   TI
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CP0434274
(5,6-Dimethoxy-indan-2-yl)-propyl-(2-pyridin-3-yl-ethyl)-amine
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C21H28N2O2
 1
1
Ki = 134 nM
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CP0505503
4-{2-[(5,6-Dimethoxy-indan-2-yl)-propyl-amino]-ethyl}-thiazol-2-ylamine
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C19H27N3O2S
 1
1
Ki = 136 nM
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CP0498130
N-[(3R)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclopentanecarbonylamino)-2-methoxybenzamide
   Show/Hide
C25H30ClN3O3
 1
1
Ki = 150 nM
   TI
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CP0380900
(8R)-8-[4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)butyl-propylamino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C27H37N3O3
 1
1
Ki = 154 nM
   TI
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CP0384025
(6-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine
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C13H18FN
 1
1
Ki = 156 nM
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CP0448144
8-{[3-(3-Chloro-phenoxy)-propyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
   Show/Hide
C25H29ClN2O2
 1
1
Ki = 159 nM
   TI
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CP0428818
8-(Cyclopropylmethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
   Show/Hide
C20H26N2O
 1
1
Ki = 164 nM
   TI
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CP0037328
(6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium
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C17H17NO2
 1
1
Ki = 170 nM
   TI
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CP0427220
N,N-dibutyl-5,6-dimethoxy-2,3-dihydro-1H-inden-2-amine
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C19H31NO2
 1
1
Ki = 180 nM
   TI
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CP0432290
(3-Phenyl-propyl)-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-ylmethyl)-amine
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C22H26N2
 1
1
Ki = 199 nM
   TI
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CP0376374
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclohexanecarbonylamino)-2-methoxybenzamide
   Show/Hide
C26H32ClN3O3
 1
1
Ki = 200 nM
   TI
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CP0489974
4-Benzoylamino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide
   Show/Hide
C26H26ClN3O3
 1
1
Ki = 200 nM
   TI
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CP0025667
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
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C18H19ClN4
 1
1
Ki = 230 nM
   TI
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CP0380845
8-(Methyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
   Show/Hide
C17H22N2O
 1
1
Ki = 258 nM
   TI
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CP0509509
(8R)-8-(dimethylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
   Show/Hide
C15H18N2O
 1
1
Ki = 265 nM
   TI
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CP0064163
(8R)-N,N-dimethyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C14H18N2
 1
1
Ki = 270 nM
   TI
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CP0469225
(5,6-Dimethoxy-indan-2-yl)-(3-fluoro-propyl)-propyl-amine
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C17H26FNO2
 1
1
Ki = 342 nM
   TI
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CP0448199
(5,6-Dimethoxy-indan-2-yl)-propyl-thiophen-3-ylmethyl-amine
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C19H25NO2S
 1
1
Ki = 374 nM
   TI
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   TS
CP0271827
(+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
   Show/Hide
C14H18N2
 1
1
Ki = 383 nM
   TI
   LI
   LO
   TS
CP0376302
8-{[4-(4,4-Dimethyl-2,6-dioxo-piperidin-1-yl)-butyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C27H37N3O3
 1
1
Ki = 450 nM
   TI
   LI
   LO
   TS
CP0497101
8-Dipropylamino-4-fluoro-3-methyl-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C20H27FN2O
 1
1
Ki = 572 nM
   TI
   LI
   LO
   TS
CP0854701
1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Dimesylate Monohydrate
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C22H30BrN3O7S2
 1
1
Ki = 616 nM
   TI
   LI
   LO
   TS
CP0221880
(S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C19H26N2O
 1
1
Ki = 751 nM
   TI
   LI
   LO
   TS
CP0437569
(8S)-8-[4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)butyl-propylamino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde;hydrate
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C27H37N3O3
 1
1
Ki = 1270 nM
   TI
   LI
   LO
   TS
CP0376022
5-Chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-N-(S)-pyrrolidin-3-yl-benzamide
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C16H20ClN3O3
 1
1
Ki = 3000 nM
   TI
   LI
   LO
   TS