General Information of the Compound
Compound ID
CP0383519
Compound Name
4-{2-[(5,6-Dimethoxy-indan-2-yl)-propyl-amino]-ethyl}-benzamide
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Structure
Formula
C23H30N2O3
Molecular Weight
382.504
Canonical SMILES
CCCN(CCc1ccc(cc1)C(N)=O)C1Cc2cc(OC)c(OC)cc2C1
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InChI
InChI=1S/C23H30N2O3/c1-4-10-25(11-9-16-5-7-17(8-6-16)23(24)26)20-12-18-14-21(27-2)22(28-3)15-19(18)13-20/h5-8,14-15,20H,4,9-13H2,1-3H3,(H2,24,26)
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InChIKey
POOHFULDFIUDII-UHFFFAOYSA-N
Physicochemical Property
logP
3.2246
Rotatable Bonds
9
Heavy Atom Count
28
Polar Areas
64.79
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11728676
SID: 16834399
ChEMBL ID
CHEMBL142956
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00957, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 123 nM
   TI
   LI
   LO
   TS
Protein ID: PT01366, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 42 nM
   TI
   LI
   LO
   TS