| Compound ID |
Compound Name |
Compound Formula |
|
CP0148502
|
4-[[4-[[4-[(3R)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol
Show/Hide
|
C23H32N2O6
|
7
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
EC50 = 0.26 nM
|
|
|
| 3 |
EC50 = 0.36 nM
|
|
|
| 4 |
EC50 = 0.47 nM
|
|
|
| 5 |
Ki = 0.15 nM
|
|
|
| 6 |
Ki = 0.36 nM
|
|
|
| 7 |
Ki = 0.46 nM
|
|
|
|
CP0376851
|
6-fluoro-N-[[1-[(4-hydroxyoxan-4-yl)methyl]piperidin-4-yl]methyl]-2-oxo-3-propan-2-ylbenzimidazole-1-carboxamide
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|
C23H33FN4O4
|
7
|
| 1 |
EC50 = 0.38 nM
|
|
|
| 2 |
EC50 = 0.9 nM
|
|
|
| 3 |
EC50 = 0.98 nM
|
|
|
| 4 |
EC50 = 1.2 nM
|
|
|
| 5 |
Ki = 1.7 nM
|
|
|
| 6 |
Ki = 4.4 nM
|
|
|
| 7 |
Ki = 5.5 nM
|
|
|
|
CP0169714
|
N-[(1S,5R)-8-[(2S)-2-hydroxy-3-(4-methylsulfonylpiperazin-1-yl)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C28H41N5O5S
|
3
|
| 1 |
EC50 = 0.3981 nM
|
|
|
| 2 |
EC50 = 1.995 nM
|
|
|
| 3 |
Ki = 12.59 nM
|
|
|
|
CP0858256
|
N-((1R,3r,5S)-8-(7-((R)-2-carbamoylpyrrolidin-1-yl)heptyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C32H47N5O3
|
2
|
| 1 |
EC50 = 0.3981 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0451460
|
N-[(1R,5S)-8-[(2S)-2-hydroxy-3-(4-methylsulfonylpiperazin-1-yl)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C26H40N6O4S
|
2
|
| 1 |
EC50 = 0.3981 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0476514
|
4-[[4-[[4-[(1R,3R)-3-hydroxycyclopentyl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol
Show/Hide
|
C24H34N2O6
|
2
|
| 1 |
EC50 = 0.4 nM
|
|
|
| 2 |
Ki = 0.5 nM
|
|
|
|
CP0388074
|
N-[(1S,5R)-8-[7-[4-(methanesulfonamidomethyl)piperidin-1-yl]heptyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C34H53N5O4S
|
2
|
| 1 |
EC50 = 0.631 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0418132
|
N-[(1S,5R)-8-[5-[2-(1H-indol-3-yl)ethyl-methylamino]pentyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C36H47N5O2
|
2
|
| 1 |
EC50 = 0.631 nM
|
|
|
| 2 |
Ki = 3.162 nM
|
|
|
|
CP0452915
|
N-[(1S,5R)-8-[7-[methyl-[3-[methyl(methylsulfonyl)amino]propyl]amino]heptyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C33H53N5O4S
|
2
|
| 1 |
EC50 = 0.631 nM
|
|
|
| 2 |
Ki = 5.012 nM
|
|
|
|
CP0484739
|
N-[(1R,5S)-8-[2-hydroxy-3-[4-(methanesulfonamidomethyl)piperidin-1-yl]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C28H44N6O4S
|
2
|
| 1 |
EC50 = 0.631 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0372483
|
4-amino-5-chloro-N-[1-[8-[2-(1H-indol-3-yl)ethyl-methylamino]octyl]piperidin-4-yl]-2-methoxybenzamide
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|
C32H46ClN5O2
|
2
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
Ki = 1.259 nM
|
|
|
|
CP0474529
|
2-oxo-N-[(1S,5R)-8-[3-(4-phenylpiperazin-1-yl)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C33H43N5O2
|
2
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0485352
|
2-oxo-N-[(1S,5R)-8-(7-piperidin-1-ylheptyl)-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C32H48N4O2
|
2
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0851979
|
N-((1R,3r,5S)-8-(2-hydroxy-3-(4-(methylsulfonyl)piperazin-1-yl)propyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C28H41N5O5S
|
2
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
Ki = 19.95 nM
|
|
|
|
CP0439902
|
N-[(1R,5S)-8-[(2R)-2-hydroxy-3-(4-methylsulfonylpiperazin-1-yl)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C26H40N6O4S
|
2
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0451458
|
N-[(1R,5S)-8-[2-hydroxy-3-(4-methylsulfonylpiperazin-1-yl)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C26H40N6O4S
|
2
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0462200
|
N-[(1R,5S)-8-[6-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]hexyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C30H47N5O2
|
2
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
Ki = 0.7943 nM
|
|
|
|
CP0395625
|
6-fluoro-N-[[1-[(4-hydroxyoxan-4-yl)methyl]piperidin-4-yl]methyl]-3,3-dimethyl-2-oxoindole-1-carboxamide
Show/Hide
|
C23H32FN3O4
|
7
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
EC50 = 0.9 nM
|
|
|
| 3 |
EC50 = 1.2 nM
|
|
|
| 4 |
EC50 = 1.3 nM
|
|
|
| 5 |
Ki = 2.7 nM
|
|
|
| 6 |
Ki = 4.6 nM
|
|
|
| 7 |
Ki = 6.8 nM
|
|
|
|
CP0397412
|
3-[(1-butylpiperidin-4-yl)methoxy]-4-cyclobutyloxy-1,2-benzoxazole
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|
C21H30N2O3
|
2
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
Ki = 0.27 nM
|
|
|
|
CP0462903
|
4-[[4-[[4-(2-methylpropoxy)-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol
Show/Hide
|
C23H34N2O5
|
2
|
| 1 |
EC50 = 0.98 nM
|
|
|
| 2 |
Ki = 0.36 nM
|
|
|
|
CP0439285
|
N-[(1S,5R)-8-[3-[4-(methanesulfonamidomethyl)piperidin-1-yl]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C30H45N5O4S
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 5.012 nM
|
|
|
|
CP0471994
|
N-[(1S,5R)-8-[8-[2-(1H-indol-3-yl)ethyl-methylamino]octyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C39H53N5O2
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 3.162 nM
|
|
|
|
CP0852003
|
1-isopropyl-2-oxo-N-((1R,3r,5S)-8-(5-(piperidin-1-yl)pentyl)-8-azabicyclo[3.2.1]octan-3-yl)-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C30H44N4O2
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 5.012 nM
|
|
|
|
CP0043343
|
(Z)-2-butenedioic acid;1-[[(Z)-(5-methoxy-3-indolylidene)methyl]amino]-2-pentylguanidine
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|
C16H23N5O
|
4
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
EC50 = 2.512 nM
|
|
|
| 3 |
Ki = 3.981 nM
|
|
|
| 4 |
Ki = 31 nM
|
|
|
|
CP0476513
|
3-[(1-butylpiperidin-4-yl)methoxy]-4-(cyclobutylmethoxy)-1,2-benzoxazole
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|
C22H32N2O3
|
2
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
Ki = 0.97 nM
|
|
|
|
CP0376852
|
3-[(1-butylpiperidin-4-yl)methoxy]-4-cyclopentyloxy-1,2-benzoxazole
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|
C22H32N2O3
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
Ki = 0.74 nM
|
|
|
|
CP0397413
|
3-[(1-butylpiperidin-4-yl)methoxy]-4-(2-methylpropoxy)-1,2-benzoxazole
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|
C21H32N2O3
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
Ki = 0.29 nM
|
|
|
|
CP0398300
|
N-[(1S,5R)-8-[(2R)-2-hydroxy-3-(4-methylsulfonylpiperazin-1-yl)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C28H41N5O5S
|
2
|
| 1 |
EC50 = 1.259 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0485232
|
4-amino-5-chloro-N-[1-[5-[2-(1H-indol-3-yl)ethyl-methylamino]pentyl]piperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C29H40ClN5O2
|
2
|
| 1 |
EC50 = 1.259 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
|
CP0858655
|
N-((1R,3r,5S)-8-(2-((2-(1H-indol-3-yl)ethyl)(methyl)amino)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C33H41N5O2
|
2
|
| 1 |
EC50 = 1.259 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0859226
|
1-isopropyl-N-((1R,3r,5S)-8-(5-(4-(methylsulfonyl)piperazin-1-yl)pentyl)-8-azabicyclo[3.2.1]octan-3-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C30H45N5O4S
|
2
|
| 1 |
EC50 = 1.259 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0896410
|
1-isopropyl-2-oxo-N-((1R,3r,5S)-8-(8-(piperidin-1-yl)octyl)-8-azabicyclo[3.2.1]octan-3-yl)-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C33H50N4O2
|
2
|
| 1 |
EC50 = 1.259 nM
|
|
|
| 2 |
Ki = 3.162 nM
|
|
|
|
CP0452914
|
N-[(1S,5R)-8-[3-(4-methylsulfonylpiperazin-1-yl)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C28H41N5O4S
|
2
|
| 1 |
EC50 = 1.585 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0459322
|
N-[(1R,5S)-8-[6-[4-(methanesulfonamidomethyl)piperidin-1-yl]hexyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C31H50N6O3S
|
2
|
| 1 |
EC50 = 1.585 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
|
CP0453462
|
4-[[4-[[4-(2-hydroxy-2-methylpropoxy)-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol
Show/Hide
|
C23H34N2O6
|
2
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
Ki = 3.6 nM
|
|
|
|
CP0396580
|
4-[[4-[[4-(oxan-4-yloxy)-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol
Show/Hide
|
C24H34N2O6
|
2
|
| 1 |
EC50 = 1.9 nM
|
|
|
| 2 |
Ki = 4.5 nM
|
|
|
|
CP0851994
|
1-isopropyl-2-oxo-N-((1R,3r,5S)-8-(3-(piperidin-1-yl)propyl)-8-azabicyclo[3.2.1]octan-3-yl)-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C28H40N4O2
|
2
|
| 1 |
EC50 = 1.995 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0451462
|
N-[(1R,5S)-8-(2-hydroxy-3-piperidin-1-ylpropyl)-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C26H39N5O2
|
2
|
| 1 |
EC50 = 1.995 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0388073
|
ethyl 4-[3-[(1S,5R)-3-[(2-oxo-1-propan-2-ylquinoline-3-carbonyl)amino]-8-azabicyclo[3.2.1]octan-8-yl]propyl]piperazine-1-carboxylate
Show/Hide
|
C30H43N5O4
|
2
|
| 1 |
EC50 = 2.512 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0398298
|
N-[(1S,5R)-8-(7-morpholin-4-ylheptyl)-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C31H46N4O3
|
2
|
| 1 |
EC50 = 2.512 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0491201
|
N-[(1S,5R)-8-[7-(4-methylsulfonylpiperazin-1-yl)heptyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C32H49N5O4S
|
2
|
| 1 |
EC50 = 2.512 nM
|
|
|
| 2 |
Ki = 10 nM
|
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|
|
CP0879818
|
1-isopropyl-N-((1R,3r,5S)-8-(3-morpholinopropyl)-8-azabicyclo[3.2.1]octan-3-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C27H38N4O3
|
2
|
| 1 |
EC50 = 2.512 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
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|
|
CP0156475
|
N-[(1R,5S)-8-[2-(4-acetylpiperazin-1-yl)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C26H38N6O2
|
3
|
| 1 |
EC50 = 2.512 nM
|
|
|
| 2 |
EC50 = 10 nM
|
|
|
| 3 |
Ki = 10 nM
|
|
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|
CP0467409
|
N-[(1R,5S)-8-[2-hydroxy-3-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C27H41N5O3
|
2
|
| 1 |
EC50 = 2.512 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0476038
|
N-[(1R,5S)-8-(6-piperidin-1-ylhexyl)-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C29H45N5O
|
2
|
| 1 |
EC50 = 2.512 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0404767
|
4-amino-5-chloro-N-[1-[8-(1,3-dioxoisoindol-2-yl)octyl]piperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C29H37ClN4O4
|
2
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0473769
|
ethyl 4-[7-[(1S,5R)-3-[(2-oxo-1-propan-2-ylquinoline-3-carbonyl)amino]-8-azabicyclo[3.2.1]octan-8-yl]heptyl]piperazine-1-carboxylate
Show/Hide
|
C34H51N5O4
|
2
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0480366
|
4-amino-5-chloro-2-methoxy-N-[1-(8-piperidin-1-yloctyl)piperidin-4-yl]benzamide
Show/Hide
|
C26H43ClN4O2
|
2
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Ki = 3.162 nM
|
|
|
|
CP0864092
|
1-isopropyl-N-((1R,3r,5S)-8-(8-(4-(methylsulfonyl)piperazin-1-yl)octyl)-8-azabicyclo[3.2.1]octan-3-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C33H51N5O4S
|
2
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0858255
|
N-((1R,3R,5S)-8-(3-((R)-2-carbamoylpyrrolidin-1-yl)propyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C28H39N5O3
|
2
|
| 1 |
EC50 = 3.981 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0467408
|
N-[(1R,5S)-8-[2-(4-methylsulfonylpiperazin-1-yl)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C25H38N6O3S
|
2
|
| 1 |
EC50 = 3.981 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0461621
|
4-amino-5-chloro-N-[1-[5-(1,3-dioxoisoindol-2-yl)pentyl]piperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C26H31ClN4O4
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
Ki = 19.95 nM
|
|
|
|
CP0471993
|
4-amino-5-chloro-2-methoxy-N-[1-(5-piperidin-1-ylpentyl)piperidin-4-yl]benzamide
Show/Hide
|
C23H37ClN4O2
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0482071
|
N-[(1R,5S)-8-[2-hydroxy-3-[methyl(propan-2-yl)amino]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C25H39N5O2
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0489757
|
N-[(1R,5S)-8-[6-[methyl(propan-2-yl)amino]hexyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C28H45N5O
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0140192
|
TD-5108
Show/Hide
|
C25H36N4O5S
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
Ki = 19.95 nM
|
|
|
|
CP0509720
|
N-[(1S,5R)-8-[3-(carbamoylamino)-2-hydroxypropyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C24H33N5O4
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0453463
|
3-[(1-butylpiperidin-4-yl)methoxy]-4-(2,2-dimethylpropoxy)-1,2-benzoxazole
Show/Hide
|
C22H34N2O3
|
2
|
| 1 |
EC50 = 6.3 nM
|
|
|
| 2 |
Ki = 5.2 nM
|
|
|
|
CP0852875
|
2-((1R,3r,5S)-3-(1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamido)-8-azabicyclo[3.2.1]octan-8-yl)ethanesulfonic acid
Show/Hide
|
C22H29N3O5S
|
2
|
| 1 |
EC50 = 6.31 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
|
CP0879817
|
1-isopropyl-N-((1R,3r,5S)-8-(2-(4-(methylsulfonyl)piperazin-1-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C27H39N5O4S
|
2
|
| 1 |
EC50 = 6.31 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0438967
|
N-[(1S,5R)-8-(3-acetamido-2-hydroxypropyl)-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C25H34N4O4
|
2
|
| 1 |
EC50 = 6.31 nM
|
|
|
| 2 |
Ki = 31.62 nM
|
|
|
|
CP0402645
|
2-oxo-N-(2-piperazin-1-ylethyl)-3-propan-2-ylbenzimidazole-1-carboxamide
Show/Hide
|
C17H25N5O2
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
Ki = 125.89 nM
|
|
|
|
CP0454266
|
2-oxo-N-[(1S,5R)-8-[7-(4-phenylpiperazin-1-yl)heptyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C37H51N5O2
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0436596
|
N-[(1S,5R)-8-[2-hydroxy-3-(methanesulfonamido)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C24H34N4O5S
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
Ki = 19.95 nM
|
|
|
|
CP0430820
|
N-[(1S,5R)-8-[3-[methyl-[3-[methyl(methylsulfonyl)amino]propyl]amino]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C29H45N5O4S
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
Ki = 199.53 nM
|
|
|
|
CP0904379
|
1-isopropyl-2-oxo-N-((1R,3r,5S)-8-(2-(piperidin-1-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C27H38N4O2
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0428779
|
methyl N-[2-hydroxy-3-[(1S,5R)-3-[(2-oxo-1-propan-2-ylquinoline-3-carbonyl)amino]-8-azabicyclo[3.2.1]octan-8-yl]propyl]-N-methylcarbamate
Show/Hide
|
C26H36N4O5
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0888613
|
rac-N-((1R,5S)-8-(2-hydroxy-3-(N-methylmethylsulfonamido)propyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C25H36N4O5S
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
Ki = 19.95 nM
|
|
|
|
CP0388107
|
4-amino-5-chloro-2-methoxy-N-[1-[5-(4-methylsulfonylpiperazin-1-yl)pentyl]piperidin-4-yl]benzamide
Show/Hide
|
C23H38ClN5O4S
|
2
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0857591
|
1-Isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic Acid{(1S,3R,5R)-8-Azabicyclo[3.2.1]oct-3-yl}amide
Show/Hide
|
C20H25N3O2
|
2
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
Ki = 251.19 nM
|
|
|
|
CP0902982
|
5-((1R,3r,5S)-3-(1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamido)-8-azabicyclo[3.2.1]octan-8-yl)pentane-1-sulfonic acid
Show/Hide
|
C25H35N3O5S
|
2
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
Ki = 1584.89 nM
|
|
|
|
CP0451457
|
N-[(1R,5S)-8-[6-(4-methylsulfonylpiperazin-1-yl)hexyl]-8-azabicyclo[3.2.1]octan-3-yl]-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C29H46N6O3S
|
2
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0416867
|
N-[(1S,5R)-8-[3-[acetyl(methyl)amino]-2-hydroxypropyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C26H36N4O4
|
2
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0436600
|
N-[(1S,5R)-8-[2-hydroxy-3-(methylcarbamoylamino)propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C25H35N5O4
|
2
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
Ki = 25.12 nM
|
|
|
|
CP0404765
|
2-oxo-N-(piperidin-4-ylmethyl)-3-propan-2-ylbenzimidazole-1-carboxamide
Show/Hide
|
C17H24N4O2
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0439631
|
4-amino-5-chloro-N-[1-(5-hydroxypentyl)piperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C18H28ClN3O3
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0439633
|
4-amino-5-chloro-N-[1-[2-[2-(1H-indol-3-yl)ethyl-methylamino]ethyl]piperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C26H34ClN5O2
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0474547
|
4-amino-5-chloro-N-[1-(8-hydroxyoctyl)piperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C21H34ClN3O3
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0879816
|
N-((1R,3r,5S)-8-(8-hydroxyoctyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C28H41N3O3
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0888510
|
N-[(1S,3R,5R)-3-Isopropyl-2-oxo-2,3-dihydrobenzoimidazole-1-carboxylic Acid(8-Azabicyclo[3.2.1]oct-3-yl)amide
Show/Hide
|
C18H24N4O2
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 316.23 nM
|
|
|
|
CP0439284
|
4-amino-5-chloro-2-methoxy-N-[1-[2-(4-methylsulfonylpiperazin-1-yl)ethyl]piperidin-4-yl]benzamide
Show/Hide
|
C20H32ClN5O4S
|
2
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
Ki = 125.89 nM
|
|
|
|
CP0903017
|
8-((1R,3r,5S)-3-(1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamido)-8-azabicyclo[3.2.1]octan-8-yl)octane-1-sulfonic acid
Show/Hide
|
C28H41N3O5S
|
2
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0163218
|
4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C23H29ClFN3O4
|
3
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
EC50 = 79.43 nM
|
|
|
| 3 |
Ki = 100 nM
|
|
|
|
CP0436599
|
N-[(1S,5R)-8-[3-[dimethylcarbamoyl(methyl)amino]-2-hydroxypropyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C27H39N5O4
|
2
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0508571
|
N-[(1S,5R)-8-[3-[carbamoyl(methyl)amino]-2-hydroxypropyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C25H35N5O4
|
2
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0454277
|
4-amino-5-chloro-2-methoxy-N-(1-pentylpiperidin-4-yl)benzamide
Show/Hide
|
C18H28ClN3O2
|
2
|
| 1 |
EC50 = 25.12 nM
|
|
|
| 2 |
Ki = 100 nM
|
|
|
|
CP0852000
|
N-((1R,3r,5S)-8-(5-hydroxypentyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C25H35N3O3
|
2
|
| 1 |
EC50 = 25.12 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0859320
|
N-((1R,3r,5S)-8-(5-(1,3-dioxoisoindolin-2-yl)pentyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C33H38N4O4
|
2
|
| 1 |
EC50 = 25.12 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0424531
|
N-[(1S,5R)-8-[(2S)-2-hydroxy-3-[methyl(methylsulfonyl)amino]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C25H36N4O5S
|
2
|
| 1 |
EC50 = 25.12 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0874063
|
N-((1R,3r,5S)-8-(2-hydroxyethyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C22H29N3O3
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
Ki = 125.89 nM
|
|
|
|
CP0880013
|
N-((1R,3r,5S)-8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C22H29N3O2
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
Ki = 125.89 nM
|
|
|
|
CP0508570
|
N-[(1S,5R)-8-[2-hydroxy-3-[methyl(methylcarbamoyl)amino]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C26H37N5O4
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
Ki = 100 nM
|
|
|
|
CP0387576
|
4-amino-5-chloro-2-methoxy-N-[1-[8-(4-methylsulfonylpiperazin-1-yl)octyl]piperidin-4-yl]benzamide
Show/Hide
|
C26H44ClN5O4S
|
2
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0404766
|
4-amino-5-chloro-2-methoxy-N-(1-octylpiperidin-4-yl)benzamide
Show/Hide
|
C21H34ClN3O2
|
2
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0851998
|
1-isopropyl-2-oxo-N-((1R,3r,5S)-8-pentyl-8-azabicyclo[3.2.1]octan-3-yl)-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C25H35N3O2
|
2
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0879819
|
N-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-1H-indazole-3-carboxamide
Show/Hide
|
C18H24N4O
|
2
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0896409
|
1-isopropyl-N-((1R,3r,5S)-8-octyl-8-azabicyclo[3.2.1]octan-3-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C28H41N3O2
|
2
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0874064
|
N-((1R,3r,5S)-8-(8-(1,3-dioxoisoindolin-2-yl)octyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C36H44N4O4
|
2
|
| 1 |
EC50 = 50.12 nM
|
|
|
| 2 |
Ki = 31.62 nM
|
|
|
|
CP0474549
|
4-amino-5-chloro-N-[1-(2-hydroxyethyl)piperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C15H22ClN3O3
|
2
|
| 1 |
EC50 = 63.1 nM
|
|
|
| 2 |
Ki = 199.53 nM
|
|
|
|
CP0404779
|
4-amino-5-chloro-N-(1-ethylpiperidin-4-yl)-2-methoxybenzamide
Show/Hide
|
C15H22ClN3O2
|
2
|
| 1 |
EC50 = 79.43 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
|
CP0858654
|
N-((1R,3r,5S)-8-(2-(1,3-dioxoisoindolin-2-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
Show/Hide
|
C30H32N4O4
|
2
|
| 1 |
EC50 = 79.43 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
|
CP0389737
|
2-oxo-N-(piperidin-4-ylmethyl)-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C19H25N3O2
|
2
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
Ki = 794.33 nM
|
|
|
|
CP0439639
|
4-amino-5-chloro-2-methoxy-N-[1-(2-piperidin-1-ylethyl)piperidin-4-yl]benzamide
Show/Hide
|
C20H31ClN4O2
|
2
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
Ki = 251.19 nM
|
|
|
|
CP0859809
|
4-amino-N-((1R,3r,5S)-8-azabicyclo[3.2.1]octan-3-yl)-5-chloro-2-methoxybenzamide
Show/Hide
|
C15H20ClN3O2
|
2
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
Ki = 158.49 nM
|
|
|
|
CP0471502
|
2-oxo-N-piperidin-4-yl-1-propan-2-ylquinoline-3-carboxamide
Show/Hide
|
C18H23N3O2
|
2
|
| 1 |
EC50 = 158.49 nM
|
|
|
| 2 |
Ki = 3162.28 nM
|
|
|
|
CP0462609
|
N-piperidin-4-yl-1-propan-2-ylindazole-3-carboxamide
Show/Hide
|
C16H22N4O
|
2
|
| 1 |
EC50 = 199.53 nM
|
|
|
| 2 |
Ki = 398.11 nM
|
|
|
|
CP0410548
|
2-oxo-N-piperidin-4-yl-3-propan-2-ylbenzimidazole-1-carboxamide
Show/Hide
|
C16H22N4O2
|
2
|
| 1 |
EC50 = 316.23 nM
|
|
|
| 2 |
Ki = 1584.89 nM
|
|
|
|
CP0372545
|
4-amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C14H20ClN3O2
|
2
|
| 1 |
EC50 = 398.11 nM
|
|
|
| 2 |
Ki = 316.23 nM
|
|
|
|
CP0404782
|
5-[4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]piperidin-1-yl]pentane-1-sulfonic acid
Show/Hide
|
C18H28ClN3O5S
|
2
|
| 1 |
EC50 = 398.11 nM
|
|
|
| 2 |
Ki = 6309.57 nM
|
|
|
|
CP0485228
|
4-amino-5-chloro-2-methoxy-N-piperidin-4-ylbenzamide
Show/Hide
|
C13H18ClN3O2
|
2
|
| 1 |
EC50 = 398.11 nM
|
|
|
| 2 |
Ki = 1584.89 nM
|
|
|
|
CP0430822
|
4-amino-5-chloro-2-methoxy-N-(2-piperazin-1-ylethyl)benzamide
Show/Hide
|
C14H21ClN4O2
|
2
|
| 1 |
EC50 = 501.19 nM
|
|
|
| 2 |
Ki = 1258.93 nM
|
|
|
|
CP0388111
|
4-amino-5-chloro-N-[1-[2-(1,3-dioxoisoindol-2-yl)ethyl]piperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C23H25ClN4O4
|
2
|
| 1 |
EC50 = 630.96 nM
|
|
|
| 2 |
Ki = 7943.28 nM
|
|
|
|
CP0372482
|
8-[4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]piperidin-1-yl]octane-1-sulfonic acid
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C21H34ClN3O5S
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2
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| 1 |
EC50 = 1000 nM
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| 2 |
Ki = 15848.93 nM
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CP0389738
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2-[4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]piperidin-1-yl]ethanesulfonic acid
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C15H22ClN3O5S
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2
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| 1 |
EC50 = 1584.89 nM
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| 2 |
Ki = 25118.86 nM
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CP0857593
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5-Methoxy-1H-indole-3-carboxylic Acid(8-Aza-bicyclo[3.2.1]-oct-3-yl)-amide
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C17H21N3O2
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2
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| 1 |
EC50 = 2511.89 nM
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| 2 |
Ki = 3162.28 nM
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CP0491202
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5-methoxy-N-(piperidin-4-ylmethyl)-1H-indole-3-carboxamide
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C16H21N3O2
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2
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| 1 |
EC50 = 6309.57 nM
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| 2 |
Ki = 3981.07 nM
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CP0904407
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[N-methyl-3H]-GR113808
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C19H27N3O4S
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1
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| 1 |
Kd = 15.81 nM
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CP0123097
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3H-GR113808
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C19H27N3O4S
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3
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| 1 |
Ki = 0.03981 nM
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| 2 |
Ki = 0.07413 nM
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| 3 |
Ki = 0.2512 nM
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CP0527150
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benzyl 4-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]butanoate
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C29H35N3O4
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1
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| 1 |
Ki = 0.04266 nM
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CP0845983
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4'-((4-(((3,4-Dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonyl)oxy)methyl)piperidin-1-yl)methyl)[1,1'-biphenyl]-2-carboxylic acid methanesulfonate
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C33H36N2O8S
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1
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| 1 |
Ki = 0.05012 nM
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CP0386316
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N-[[1-[[4-(2-methylpropylsulfonylamino)phenyl]methyl]piperidin-4-yl]methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide
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C29H38N4O4S
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1
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| 1 |
Ki = 0.05012 nM
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CP0120660
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N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethyleneoxy)-1H-indole-3-carboxamide
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C22H31N3O2
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4
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| 1 |
Ki = 0.05248 nM
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| 2 |
Ki = 0.1 nM
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| 3 |
Ki = 0.1585 nM
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| 4 |
Ki = 0.3981 nM
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CP0382610
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tert-butyl 6-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]hexanoate
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C28H41N3O4
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1
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| 1 |
Ki = 0.0537 nM
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CP0845984
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Methyl 4'-((4-((3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamido)-methyl)piperidin-1-yl)methyl)[1,1'-biphenyl]-2-carboxylate
Show/Hide
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C33H35N3O4
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1
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| 1 |
Ki = 0.0631 nM
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CP0468254
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2,2-dimethylpropanoyloxymethyl 6-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]hexanoate
Show/Hide
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C30H43N3O6
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1
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| 1 |
Ki = 0.06457 nM
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CP0746540
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1-Isopropyl-N-[[1-(2-phenylethyl)-4-piperidinyl]methyl]-1H-indazole-3-carboxamide hydrochloride
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C25H33ClN4O
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1
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| 1 |
Ki = 0.07943 nM
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CP0379075
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[1-(2,3-dihydroxypropyl)piperidin-4-yl]methyl 3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxylate
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C21H28N2O5
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1
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| 1 |
Ki = 0.07943 nM
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CP0778942
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1-Isopropyl-N-[[1-(2-pyridin-2-ylethyl)-4-piperidinyl]methyl]-1Hindazole-3-carboxamide hydrochloride
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C24H32ClN5O
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1
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| 1 |
Ki = 0.1 nM
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CP0382609
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ethyl 4-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]butanoate
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C24H33N3O4
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1
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| 1 |
Ki = 0.1023 nM
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CP0046582
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methyl 6-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]hexanoate
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C25H35N3O4
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1
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| 1 |
Ki = 0.1072 nM
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CP0501975
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benzyl 6-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]hexanoate
Show/Hide
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C31H39N3O4
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1
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| 1 |
Ki = 0.1413 nM
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CP0852268
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N-[[1-(2-Cyclohexylethyl)-4-piperidinyl]methyl]-1-isopropyl-1Hindazole-3-carboxamide hydrochloride
Show/Hide
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C25H39ClN4O
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1
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| 1 |
Ki = 0.1585 nM
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CP0411772
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methyl 10-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]decanoate
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C29H43N3O4
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1
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| 1 |
Ki = 0.195 nM
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CP0778940
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N-[[1-[2-(4-Aminophenyl)ethyl]-4-piperidinyl]methyl]-1-isopropyl-1H-indazole-3-carboxamide dihydrochloride
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C25H35Cl2N5O
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1
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| 1 |
Ki = 0.1995 nM
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CP0481979
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N-[[1-[[4-(2-methylpropylsulfonylamino)phenyl]methyl]piperidin-4-yl]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide
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C26H35N3O5S
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1
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| 1 |
Ki = 0.1995 nM
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CP0489429
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N-[[1-[[4-(cyclohexylsulfonylamino)phenyl]methyl]piperidin-4-yl]methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide
Show/Hide
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C31H40N4O4S
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1
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| 1 |
Ki = 0.1995 nM
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CP0489430
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N-[[1-[[4-(methanesulfonamido)phenyl]methyl]piperidin-4-yl]methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide
Show/Hide
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C26H32N4O4S
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1
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| 1 |
Ki = 0.1995 nM
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CP0510285
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N-[[1-[[4-(methanesulfonamido)phenyl]methyl]piperidin-4-yl]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide
Show/Hide
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C23H29N3O5S
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1
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| 1 |
Ki = 0.1995 nM
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CP0411770
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tert-butyl 4-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]butanoate
Show/Hide
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C26H37N3O4
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1
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| 1 |
Ki = 0.2344 nM
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CP0895862
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1-Isopropyl-N-[[1-[2-(4-hydroxyphenyl)ethyl]-4-piperidinyl]-methyl]-1H-indazole-3-carboxamide hydrochloride
Show/Hide
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C25H33ClN4O2
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1
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| 1 |
Ki = 0.2512 nM
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CP0398053
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N-[[1-[[4-(butylsulfonylamino)phenyl]methyl]piperidin-4-yl]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide
Show/Hide
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C26H35N3O5S
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1
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| 1 |
Ki = 0.2512 nM
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CP0652596
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1-Isopropyl-N-[[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl]-1H-indazole-3-carboxamide hydrochloride
Show/Hide
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C20H32ClN5O3S
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1
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| 1 |
Ki = 0.3162 nM
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CP0399481
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2-[4-[[4-(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonyloxymethyl)piperidin-1-yl]methyl]phenyl]propanoic acid
Show/Hide
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C28H32N2O5
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1
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| 1 |
Ki = 0.3162 nM
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CP0498900
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2,2-dimethylpropanoyloxymethyl 4-[[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]methyl]benzoate
Show/Hide
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C32H39N3O6
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1
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| 1 |
Ki = 0.3388 nM
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CP0501976
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methyl 12-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]dodecanoate
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C31H47N3O4
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1
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| 1 |
Ki = 0.3388 nM
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CP0690769
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1-Isopropyl-N-[[1-[2-morpholin-4-ylethyl]-4-piperidinyl]methyl]-1H-indazole-3-carboxamide dihydrochloride
Show/Hide
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C23H37Cl2N5O2
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1
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| 1 |
Ki = 0.3981 nM
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CP0877527
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1-Isopropyl-N-[[1-[3-(methylamino)-3-oxo-1-propyl]-4-piperidinyl]methyl]-1H-indazole-3-carboxamide hydrochloride
Show/Hide
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C21H32ClN5O2
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1
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| 1 |
Ki = 0.5012 nM
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CP0924842
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1-Isopropyl-N-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-indazole-3-carboxamide hydrochloride
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C24H31ClN4O
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1
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| 1 |
Ki = 0.631 nM
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CP0901781
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4'-((4-((3,4-Dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamido)methyl)piperidin-1-yl)methyl)[1,1'-biphenyl]-2-carboxylic acid
Show/Hide
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C32H33N3O4
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1
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| 1 |
Ki = 0.631 nM
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CP0382608
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tert-butyl 2-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]acetate
Show/Hide
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C24H33N3O4
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1
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| 1 |
Ki = 0.7586 nM
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CP0046312
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4-[2-[4-[[(1-propan-2-ylindazole-3-carbonyl)amino]methyl]piperidin-1-yl]ethyl]benzoic acid
Show/Hide
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C26H32N4O3
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1
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| 1 |
Ki = 0.7943 nM
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CP0716507
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N-[[1-[3-(Dimethylamino)propyl]-4-piperidinyl]methyl]-1-isopropyl-1H-indazole-3-carboxamide maleate
Show/Hide
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C26H39N5O5
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1
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| 1 |
Ki = 0.7943 nM
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CP0382604
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4-[4-(1H-indole-3-carbonyloxymethyl)piperidin-1-yl]butanoic acid
Show/Hide
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C19H24N2O4
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1
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| 1 |
Ki = 0.8128 nM
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CP0481952
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N-[[1-[[4-(butylsulfonylamino)phenyl]methyl]piperidin-4-yl]methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide
Show/Hide
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C29H38N4O4S
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1
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| 1 |
Ki = 1 nM
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CP0501973
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3-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]propanoic acid
Show/Hide
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C21H27N3O4
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1
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| 1 |
Ki = 1.122 nM
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CP0411769
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N-[[1-(2-diethoxyphosphorylethyl)piperidin-4-yl]methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide
Show/Hide
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C24H36N3O5P
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1
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| 1 |
Ki = 1.259 nM
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CP0917665
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1-Isopropyl-N-[[1-[2-(4-nitrophenyl)ethyl]-4-piperidinyl]methyl]-1H-indazole-3-carboxamide oxalate
Show/Hide
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C27H33N5O7
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1
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| 1 |
Ki = 1.259 nM
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CP0386315
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N-[[1-[[4-(cyclohexylsulfonylamino)phenyl]methyl]piperidin-4-yl]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide
Show/Hide
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C28H37N3O5S
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1
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| 1 |
Ki = 1.259 nM
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CP0398052
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3-[[4-(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonyloxymethyl)piperidin-1-yl]methyl]cyclopentane-1-carboxylic acid
Show/Hide
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C25H32N2O5
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1
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| 1 |
Ki = 1.259 nM
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CP0519163
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3-[[4-(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonyloxymethyl)piperidin-1-yl]methyl]cyclohexane-1-carboxylic acid
Show/Hide
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C26H34N2O5
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1
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| 1 |
Ki = 1.259 nM
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CP0405351
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(1-butylpiperidin-4-yl)methyl 8-amino-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate
Show/Hide
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C19H28N2O4
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1
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| 1 |
Ki = 1.4 nM
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CP0046583
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6-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]hexanoic acid
Show/Hide
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C24H33N3O4
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1
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| 1 |
Ki = 1.549 nM
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CP0383749
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5-[[4-(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonyloxymethyl)piperidin-1-yl]methyl]tricyclo[2.2.1.02,6]heptane-3-carboxylic acid
Show/Hide
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C27H32N2O5
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1
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| 1 |
Ki = 1.585 nM
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CP0382607
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4-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]butanoic acid
Show/Hide
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C22H29N3O4
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1
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| 1 |
Ki = 1.995 nM
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CP0046273
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2-methyl-4-[[1-(2-phenylethyl)piperidin-4-yl]methoxy]pyrrolo[3,4-c]quinoline
Show/Hide
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C26H29N3O
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1
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| 1 |
Ki = 1.995 nM
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CP0046314
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4-[2-[4-[(2-methylpyrrolo[3,4-c]quinolin-4-yl)oxymethyl]piperidin-1-yl]ethyl]benzoic acid
Show/Hide
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C27H29N3O3
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1
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| 1 |
Ki = 1.995 nM
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CP0338298
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N-[4-[2-[4-[(2-methylpyrrolo[3,4-c]quinolin-4-yl)oxymethyl]piperidin-1-yl]ethyl]phenyl]acetamide
Show/Hide
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C28H32N4O2
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1
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| 1 |
Ki = 1.995 nM
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CP0043647
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(1-Butylpiperidin-4-yl)methyl 7-chloro-8-(methylamino)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate
Show/Hide
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C20H29ClN2O4
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1
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| 1 |
Ki = 2 nM
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CP0382605
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5-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]pentanoic acid
Show/Hide
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C23H31N3O4
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1
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| 1 |
Ki = 2.042 nM
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CP0043648
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(1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate
Show/Hide
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C19H27FN2O4
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1
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| 1 |
Ki = 2.1 nM
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CP0056169
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(1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-dihydrobenzo-[b][1,4]dioxine-5-carboxylate
Show/Hide
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C19H27IN2O4
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1
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| 1 |
Ki = 2.2 nM
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CP0036636
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(1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxybenzoate
Show/Hide
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C18H28N2O3
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1
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| 1 |
Ki = 2.4 nM
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CP0478574
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12-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]dodecanoic acid
Show/Hide
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C30H45N3O4
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1
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| 1 |
Ki = 2.455 nM
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CP0768837
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2-Methyl-4-[[1-(2-morpholin-4-ylethyl)-4-piperidinyl]methoxy]-2H-pyrrolo[3,4-c]quinoline hydrochloride
Show/Hide
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C24H33ClN4O2
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1
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| 1 |
Ki = 2.512 nM
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CP0845986
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(1-((2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl)methyl)piperidin-4-yl)methyl 3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxylate
Show/Hide
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C32H32N6O3
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1
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| 1 |
Ki = 2.512 nM
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CP0501974
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2-[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]acetic acid
Show/Hide
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C20H25N3O4
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1
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| 1 |
Ki = 2.818 nM
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CP0845987
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N-((1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)piperidin-4-yl)methyl)-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide
Show/Hide
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C32H33N7O2
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1
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| 1 |
Ki = 3.981 nM
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CP0427643
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(1-Butylpiperidin-4-yl)methyl 7-bromo-8-(methylamino)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate
Show/Hide
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C20H29BrN2O4
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1
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| 1 |
Ki = 4.5 nM
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CP0411768
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4-[[4-[(3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carbonylamino)methyl]piperidin-1-yl]methyl]benzoic acid
Show/Hide
|
C26H29N3O4
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1
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| 1 |
Ki = 5.012 nM
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CP0811793
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4-[[1-[2-(4-Aminophenyl)ethyl]-4-piperidinyl]methoxy]-2-methyl-2H-pyrrolo[3,4-c]quinoline hydrochloride
Show/Hide
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C26H31ClN4O
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1
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| 1 |
Ki = 5.012 nM
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CP0405352
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(1-Butylpiperidin-4-yl)methyl 8-amino-7-methyl-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate
Show/Hide
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C20H30N2O4
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1
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| 1 |
Ki = 6.3 nM
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CP0405353
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(1-Butylpiperidin-4-yl)methyl 7-iodo-8-(methylamino)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate
Show/Hide
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C20H29IN2O4
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1
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| 1 |
Ki = 7.4 nM
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CP0427656
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(1-Butylpiperidin-4-yl)methyl 8-Amino-7-nitro-2,3-dihydrobenzo-[b][1,4]dioxine-5-carboxylate
Show/Hide
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C19H27N3O6
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1
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| 1 |
Ki = 7.8 nM
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CP0431494
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N-(piperidin-4-ylmethyl)-1-propan-2-ylindazole-3-carboxamide
Show/Hide
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C17H24N4O
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1
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| 1 |
Ki = 7.943 nM
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CP0524042
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4-[(1-butylpiperidin-4-yl)methoxy]-2-methylpyrrolo[3,4-c]quinoline
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C22H29N3O
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1
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| 1 |
Ki = 7.943 nM
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CP0427638
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(1-Butylpiperidin-4-yl)methyl 8-(methylamino)-2,3-dihydrobenzo-[b][1,4]dioxine-5-carboxylate
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C20H30N2O4
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1
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| 1 |
Ki = 9.1 nM
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CP0336202
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[4-[2-[4-[(2-methylpyrrolo[3,4-c]quinolin-4-yl)oxymethyl]piperidin-1-yl]ethyl]phenyl]methanol
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C27H31N3O2
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1
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| 1 |
Ki = 10 nM
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CP0427642
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(1-Butylpiperidin-4-yl)methyl 4-Amino-3-(2-fluoroethoxy)-benzoate
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C19H29FN2O3
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1
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| 1 |
Ki = 11 nM
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CP0439497
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(1-Pentylpiperidin-4-yl)methyl 4-Amino-3-methoxybenzoate
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C19H30N2O3
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1
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| 1 |
Ki = 12 nM
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CP0417294
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(1-Propylpiperidin-4-yl)methyl 4-Amino-3-methoxybenzoate
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C17H26N2O3
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1
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| 1 |
Ki = 17 nM
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CP0439469
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(1-Butylpiperidin-4-yl)methyl 4-Amino-3-(fluoromethoxy)-benzoate
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C18H27FN2O3
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1
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| 1 |
Ki = 17 nM
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CP0159501
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4-[[1-[2-[4-(methoxymethyl)phenyl]ethyl]piperidin-4-yl]methoxy]-2-methylpyrrolo[3,4-c]quinoline
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C28H33N3O2
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1
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| 1 |
Ki = 19.95 nM
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CP0500281
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N-[[1-methyl-1-(2-phenylethyl)piperidin-1-ium-4-yl]methyl]-1-propan-2-ylindazole-3-carboxamide;iodide
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C26H35IN4O
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1
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| 1 |
Ki = 31.62 nM
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CP0417278
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(1-Butylpiperidin-4-yl)methyl 8-amino-7-cyano-2,3-dihydrobenzo-[b][1,4]dioxine-5-carboxylate
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C20H27N3O4
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1
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| 1 |
Ki = 33 nM
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CP0417280
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(1-Butylpiperidin-4-yl)methyl 7-cyano-8-(methylamino)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate
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C21H29N3O4
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1
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| 1 |
Ki = 37 nM
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CP0405354
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(1-Butylpiperidin-4-yl)methyl 4-Amino-2-methoxybenzoate
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C18H28N2O3
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1
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| 1 |
Ki = 50 nM
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CP0514710
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methyl N-[2-hydroxy-3-[(1S,5R)-3-[(2-oxo-1-propan-2-ylquinoline-3-carbonyl)amino]-8-azabicyclo[3.2.1]octan-8-yl]propyl]carbamate
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C25H34N4O5
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1
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| 1 |
Ki = 50.12 nM
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CP0512373
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N-[(1S,5R)-8-[3-(dimethylcarbamoylamino)-2-hydroxypropyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide
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C26H37N5O4
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1
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| 1 |
Ki = 100 nM
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CP0411767
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ethyl 4-[4-[(1H-indole-3-carbonylamino)methyl]piperidin-1-yl]butanoate
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C21H29N3O3
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1
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| 1 |
Ki = 107.15 nM
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CP0922293
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2-Isopropyl-4-[[1-(2-phenylethyl)-4-piperidinyl]methoxy]-2Hpyrrolo[3,4-c]quinoline hydrochloride
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C28H34ClN3O
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1
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| 1 |
Ki = 125.89 nM
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CP0445897
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2-[2-[4-[(2-methylpyrrolo[3,4-c]quinolin-4-yl)oxymethyl]piperidin-1-yl]ethyl]benzoic acid
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C27H29N3O3
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1
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| 1 |
Ki = 199.53 nM
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CP0372524
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5-methoxy-N-(2-piperazin-1-ylethyl)-1H-indole-3-carboxamide
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C16H22N4O2
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1
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| 1 |
Ki = 316.23 nM
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CP0523286
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2-methyl-4-(piperidin-4-ylmethoxy)pyrrolo[3,4-c]quinoline
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C18H21N3O
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1
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| 1 |
Ki = 398.11 nM
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CP0001238
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14C-5-hydroxy tryptamine creatinine disulfate
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C10H12N2O
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1
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| 1 |
Ki = 500 nM
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CP0511163
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N-[[1-[[4-(cyclohexylsulfonylamino)phenyl]methyl]piperidin-4-yl]methyl]-1H-indole-3-carboxamide
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C28H36N4O3S
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1
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| 1 |
Ki = 501.19 nM
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CP0511162
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N-[[1-[[4-(benzylsulfonylamino)phenyl]methyl]piperidin-4-yl]methyl]-1H-indole-3-carboxamide
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C29H32N4O3S
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1
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| 1 |
Ki = 1000 nM
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CP0845072
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(cyclo[(6-bromo-8-entryptophan)arginine])
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C17H19BrN6O2
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1
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| 1 |
Ki = 1910 nM
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CP0439630
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5-methoxy-N-piperidin-4-yl-1H-indole-3-carboxamide
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C15H19N3O2
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1
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| 1 |
Ki = 3162.28 nM
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CP0382603
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4-[4-[(1H-indole-3-carbonylamino)methyl]piperidin-1-yl]butanoic acid
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C19H25N3O3
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1
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| 1 |
Ki = 3630.78 nM
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CP0417279
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4-Amino-N-((1-butylpiperidin-4-yl)methyl)-3-methoxybenzamide
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C18H29N3O2
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1
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| 1 |
Ki = 8664 nM
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CP0372923
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2-[3-[(2S,5S)-5-[(6-bromo-1H-indol-3-yl)methyl]-3,6-dioxopiperazin-2-yl]propyl]guanidine
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C17H21BrN6O2
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1
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| 1 |
Ki > 10000 nM
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CP0391901
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3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
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C13H14ClN3
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1
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| 1 |
Ki > 10000 nM
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CP0391904
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3-(4-methylphenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
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C14H17N3
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1
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| 1 |
Ki > 10000 nM
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CP0391906
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3-(4-fluorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
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C13H14FN3
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1
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| 1 |
Ki > 10000 nM
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CP0391907
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3-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
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C13H13ClN2O
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1
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| 1 |
Ki > 10000 nM
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CP0391908
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3-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
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C13H13FN2O
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1
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| 1 |
Ki > 10000 nM
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CP0456120
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3-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
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C14H16N2O
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1
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| 1 |
Ki > 10000 nM
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