Brief Information of the Compound and Protein
Compound Name
N-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yl)-1-isopropyl-1H-indazole-3-carboxamide
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PubChem ID
SID: 15794776
Canonical SMILES
CC(C)n1nc(C(=O)N[C@H]2C[C@H]3CC[C@@H](C2)N3)c2ccccc21
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Compound Formula C18H24N4O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
>
Serotonin receptor
Uniprot ID
Q13639
Gene Name
HTR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 39.81 nM
   TI
   LI
   LO
   TS
2
Ki = 63.1 nM
   TI
   LI
   LO
   TS