Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethyleneoxy)-1H-indole-3-carboxamide
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 PubChem ID
CID: 177336
SID: 14901873
Canonical SMILES
CCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1
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Compound Formula C22H31N3O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
Q13639
Gene Name
HTR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
Ki = 0.05248 nM
   TI
   LI
   LO
   TS
2
Ki = 0.1 nM
   TI
   LI
   LO
   TS
3
Ki = 0.1585 nM
   TI
   LI
   LO
   TS
4
Ki = 0.3981 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.631 nM
2 Ki = 0.2512 nM
3 Ki = 0.5012 nM
4 Ki = 1.585 nM