Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(Z)-2-butenedioic acid;1-[[(Z)-(5-methoxy-3-indolylidene)methyl]amino]-2-pentylguanidine
    Show/Hide
 PubChem ID
CID: 135409453
SID: 14776171
Canonical SMILES
CCCCCN=C(N)NN=Cc1c[nH]c2ccc(OC)cc12
    Show/Hide
Compound Formula C16H23N5O
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
Q13639
Gene Name
HTR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
2
EC50 = 2.512 nM
   TI
   LI
   LO
   TS
3
Ki = 3.981 nM
   TI
   LI
   LO
   TS
4
Ki = 31 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 15.85 nM
2 Ki = 3.981 nM