| Compound ID |
Compound Name |
Compound Formula |
|
CP0716731
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(phenylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
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|
C22H22F2N4O3S
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
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CP0385821
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-[3-(trifluoromethyl)phenyl]sulfonyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]oxan-3-amine
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|
C23H21F5N4O3S
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
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CP0158125
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(1-methylimidazol-4-yl)sulfonyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]oxan-3-amine
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|
C20H22F2N6O3S
|
1
|
| 1 |
IC50 = 41000 nM
|
|
|
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CP0731719
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(3-(phenylsulfonyl)pyrrolo[3,4-c]pyrazol-5(1H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
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|
C22H22F2N4O3S
|
1
|
| 1 |
IC50 = 41000 nM
|
|
|
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CP0946601
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(1-(1-methyl-1H-imidazol-4-ylsulfonyl)pyrrolo[3,4-c]pyrazol-5(1H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
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|
C20H22F2N6O3S
|
1
|
| 1 |
IC50 = 44000 nM
|
|
|
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CP0124388
|
N-[5-[(3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)oxan-3-yl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]pyridine-4-carboxamide
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|
C22H22F2N6O2
|
1
|
| 1 |
IC50 = 47000 nM
|
|
|
|
CP0472462
|
N-[5-[(3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)oxan-3-yl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]-1,3-thiazole-2-carboxamide
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|
C20H20F2N6O2S
|
1
|
| 1 |
IC50 = 55000 nM
|
|
|
|
CP0850422
|
(2R,3S,5R)-5-(2-(cyclopentylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)-2-(2,5-difluorophenyl)tetrahydro-2H-pyran-3-amine
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|
C21H26F2N4O3S
|
1
|
| 1 |
IC50 = 60000 nM
|
|
|
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CP0880934
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(3-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(1H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
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|
C17H20F2N4O3S
|
1
|
| 1 |
IC50 = 60000 nM
|
|
|
|
CP0716732
|
N-(5-((3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)tetrahydro-2H-pyran-3-yl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-1H-imidazole-4-sulfonamide
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|
C19H21F2N7O3S
|
1
|
| 1 |
IC50 = 62000 nM
|
|
|
|
CP0314285
|
N-[5-[(3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)oxan-3-yl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]ethanesulfonamide
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|
C18H23F2N5O3S
|
1
|
| 1 |
IC50 = 89000 nM
|
|
|
|
CP0472609
|
N-[5-[(3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)oxan-3-yl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]cyclopropanesulfonamide
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|
C19H23F2N5O3S
|
1
|
| 1 |
IC50 = 91000 nM
|
|
|
|
CP0059208
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-5-yl)oxan-3-amine
Show/Hide
|
C16H18F2N4O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0064959
|
N-[5-[(3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)oxan-3-yl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]-1-pyridin-4-ylmethanesulfonamide
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|
C22H24F2N6O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0064961
|
MK-3102
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|
C17H20F2N4O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0124386
|
N-[5-[(3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)oxan-3-yl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]cyclopropanecarboxamide
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|
C20H23F2N5O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0170545
|
N-[5-[(3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)oxan-3-yl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]propanamide
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|
C19H23F2N5O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0231807
|
N-[5-[(3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)oxan-3-yl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]methanesulfonamide
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|
C17H21F2N5O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0472383
|
N-[5-[(3R,5S,6R)-5-amino-6-(2,5-difluorophenyl)oxan-3-yl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]-2,2,2-trifluoroethanesulfonamide
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|
C18H20F5N5O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0688614
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(ethylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
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|
C18H22F2N4O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0690535
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(isopropylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
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|
C19H24F2N4O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0716729
|
US8592371, 3
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|
C21H26F2N4O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0751589
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(propylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
Show/Hide
|
C19H24F2N4O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0767642
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(3-(isopropylsulfonyl)pyrrolo[3,4-c]pyrazol-5(1H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
Show/Hide
|
C19H24F2N4O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0804285
|
(2R,3S,5R)-5-(1-(cyclopropylsulfonyl)pyrrolo[3,4-c]pyrazol-5(1H,4H,6H)-yl)-2-(2,5-difluorophenyl)tetrahydro-2H-pyran-3-amine
Show/Hide
|
C19H22F2N4O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0834742
|
(2R,3S,5R)-5-(2-(cyclopropylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)-2-(2,5-difluorophenyl)tetrahydro-2H-pyran-3-amine
Show/Hide
|
C19H22F2N4O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
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CP0839518
|
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(trifluoromethylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
Show/Hide
|
C17H17F5N4O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
