Brief Information of the Compound and Protein
Compound Name
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(1-methylimidazol-4-yl)sulfonyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]oxan-3-amine
    Show/Hide
PubChem ID
CID: 127035243
Canonical SMILES
Cn1cnc(c1)S(=O)(=O)n1cc2CN(Cc2n1)[C@H]1CO[C@@H]([C@@H](N)C1)c1cc(F)ccc1F
    Show/Hide
Compound Formula C20H22F2N6O3S
Compound Structure
Protein Name
Dipeptidyl peptidase 8
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S9B subfamily
Uniprot ID
Q6V1X1
Gene Name
DPP8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 41000 nM
   TI
   LI
   LO
   TS