Brief Information of the Compound and Protein
Compound Name
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(phenylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine
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PubChem ID
CID: 127035244
Canonical SMILES
N[C@H]1C[C@@H](N2Cc3cn(S(=O)(=O)c4ccccc4)nc3C2)CO[C@@H]1c1cc(F)ccc1F
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Compound Formula C22H22F2N4O3S
Compound Structure
Protein Name
Dipeptidyl peptidase 8
Protein Classification
Enzyme
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Protease
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Serine protease
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Serine protease SC clan
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Serine protease S9B subfamily
Uniprot ID
Q6V1X1
Gene Name
DPP8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 25000 nM
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