| Compound ID |
Compound Name |
Compound Formula |
|
CP0421231
|
N-[[1-[4-[[3-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamoylamino]-2-(trifluoromethyl)phenyl]piperidin-4-yl]methyl]propanamide
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|
C34H36F3N5O5
|
2
|
| 1 |
EC50 < 100 nM
|
|
|
| 2 |
GI50 = 4 nM
|
|
|
|
CP0035428
|
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
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|
C29H27F3N6O
|
2
|
| 1 |
GI50 = 2.2 nM
|
|
|
| 2 |
GI50 = 9.6 nM
|
|
|
|
CP0002211
|
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
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|
C22H27FN4O2
|
1
|
| 1 |
GI50 = 5 nM
|
|
|
|
CP0002778
|
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
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|
C29H31N7O
|
3
|
| 1 |
GI50 = 10 nM
|
|
|
| 2 |
GI50 = 27 nM
|
|
|
| 3 |
GI50 >= 30000 nM
|
|
|
|
CP0096180
|
1-[5-tert-butyl-2-(3-nitrophenyl)pyrazol-3-yl]-3-[4-(quinazolin-4-ylamino)phenyl]urea
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|
C28H26N8O3
|
2
|
| 1 |
GI50 = 10.8 nM
|
|
|
| 2 |
GI50 = 23.6 nM
|
|
|
|
CP0240254
|
1-[4-[(6-aminoquinazolin-4-yl)amino]phenyl]-3-[4-chloro-3-(trifluoromethyl)phenyl]urea
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|
C22H16ClF3N6O
|
2
|
| 1 |
GI50 = 11.8 nM
|
|
|
| 2 |
GI50 = 121 nM
|
|
|
|
CP0059308
|
1-[2-(3-aminophenyl)-5-tert-butylpyrazol-3-yl]-3-[4-(quinazolin-4-ylamino)phenyl]urea
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|
C28H28N8O
|
2
|
| 1 |
GI50 = 17.2 nM
|
|
|
| 2 |
GI50 = 27.7 nM
|
|
|
|
CP0180491
|
1-[2-(3-aminophenyl)-5-tert-butylpyrazol-3-yl]-3-[4-[(6-aminoquinazolin-4-yl)amino]phenyl]urea
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|
C28H29N9O
|
2
|
| 1 |
GI50 = 105 nM
|
|
|
| 2 |
GI50 = 110 nM
|
|
|
|
CP0490017
|
1,4-Hybrid, 5
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|
C31H33N9O2
|
2
|
| 1 |
GI50 = 208 nM
|
|
|
| 2 |
GI50 = 324 nM
|
|
|
|
CP0368036
|
N-[4-[4-[[2-(3-aminophenyl)-5-tert-butylpyrazol-3-yl]carbamoylamino]anilino]quinazolin-6-yl]-3-(4-methylpiperazin-1-yl)propanamide
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|
C36H43N11O2
|
2
|
| 1 |
GI50 = 385 nM
|
|
|
| 2 |
GI50 = 402 nM
|
|
|
