Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[4-[[2-(3-aminophenyl)-5-tert-butylpyrazol-3-yl]carbamoylamino]anilino]quinazolin-6-yl]-3-(4-methylpiperazin-1-yl)propanamide
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 PubChem ID
CID: 60202315
Canonical SMILES
CN1CCN(CCC(=O)Nc2ccc3ncnc(Nc4ccc(NC(=O)Nc5cc(nn5-c5cccc(N)c5)C(C)(C)C)cc4)c3c2)CC1
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Compound Formula C36H43N11O2
Compound Structure
Protein Name
 Protein Info 
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000122 GIST-T1
 Cell Line Info 
Homo sapiens (Human)  2
1
GI50 = 385 nM
   TI
   LI
   LO
   TS
2
GI50 = 402 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.5 nM
2 IC50 = 6.9 nM