Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1,4-Hybrid, 5
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 PubChem ID
CID: 70701950
Canonical SMILES
CCC(=O)Nc1ccc2ncnc(Nc3ccc(NC(=O)Nc4cc(nn4-c4cccc(N)c4)C(C)(C)C)cc3)c2c1
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Compound Formula C31H33N9O2
Compound Structure
Protein Name
 Protein Info 
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000122 GIST-T1
 Cell Line Info 
Homo sapiens (Human)  2
1
GI50 = 208 nM
   TI
   LI
   LO
   TS
2
GI50 = 324 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.6 nM
2 IC50 = 22.1 nM