General Information of the Compound
| Compound ID |
CP0338847
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| Compound Name |
2-methoxy-6-[(E)-[(6-methoxy-2-methylquinolin-4-yl)hydrazinylidene]methyl]phenol
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| Structure |
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| Formula |
C19H19N3O3
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| Molecular Weight |
337.379
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| Canonical SMILES |
COc1ccc2nc(C)cc(N\N=C\c3cccc(OC)c3O)c2c1
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| InChI |
InChI=1S/C19H19N3O3/c1-12-9-17(15-10-14(24-2)7-8-16(15)21-12)22-20-11-13-5-4-6-18(25-3)19(13)23/h4-11,23H,1-3H3,(H,21,22)/b20-11+
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| InChIKey |
AULQYWKIJVZYFH-RGVLZGJSSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT06124, Paired box protein Pax-8
Protein ID: PT02130, Ribosyldihydronicotinamide dehydrogenase [quinone]
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000084 | SK-OV-3 | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 2100 nM
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TI
LI
LO
TS
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