General Information of the Cell Line
Cell Line ID
CL000020
Cell Line Name
Neuro-2a
Synonyms
NEURO-2A
Neuro 2a
Neuro2a
Neuro2A
N-2a
N2a
N2A
Nb2a
NB2a
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0470
Tissue Information
Peripheral nervous system
Disease
Mouse neuroblastoma (NCIt: C21993)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT03206, Beta-secretase 1
Compound ID Compound Name Compound Formula
CP0188117
N-[3-[(3R)-5-amino-3-methyl-2,6-dihydro-1,4-oxazin-3-yl]-4-fluorophenyl]-5-methoxypyrazine-2-carboxamide
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C17H18FN5O3
 1
1
IC50 = 4.3 nM
   TI
   LI
   LO
   TS
CP0202840
N-[3-[(3R)-5-amino-3-methyl-2,6-dihydro-1,4-oxazin-3-yl]-4-fluorophenyl]-5-chloropyridine-2-carboxamide
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C17H16ClFN4O2
 1
1
IC50 = 4.5 nM
   TI
   LI
   LO
   TS
CP0204164
N-[3-[(3R)-5-amino-3-methyl-2,6-dihydro-1,4-oxazin-3-yl]phenyl]-5-chloropyridine-2-carboxamide
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C17H17ClN4O2
 1
1
IC50 = 7.4 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0416898
1-(3-phenylmethoxypyridin-2-yl)-3-(2-piperazin-1-ylethyl)urea
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C19H25N5O2  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Peripheral nervous system)
Cell Line Name Organism Disease
ScN2a Mus musculus (Mouse) Mouse neuroblastoma
N18TG2 Mus musculus (Mouse) Mouse neuroblastoma
N1E-115 Mus musculus (Mouse) Mouse neuroblastoma
ScN2a-cl3 Mus musculus (Mouse) Mouse neuroblastoma
S16 Rattus norvegicus (Rat) -