Brief Information of the Compound and Protein
Compound Name
N-[3-[(3R)-5-amino-3-methyl-2,6-dihydro-1,4-oxazin-3-yl]-4-fluorophenyl]-5-methoxypyrazine-2-carboxamide
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PubChem ID
CID: 122195837
Canonical SMILES
COc1cnc(cn1)C(=O)Nc1ccc(F)c(c1)[C@]1(C)COCC(N)=N1
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Compound Formula C17H18FN5O3
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
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Protease
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Aspartic protease
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Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56818
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000020 Neuro-2a Mus musculus (Mouse)  1
1
IC50 = 4.3 nM
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