| Compound ID |
Compound Name |
Compound Formula |
|
CP0418485
|
2-[(4aR,5S)-4a-methyl-1-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]propan-2-ol
Show/Hide
|
C22H28N2O
|
2
|
| 1 |
EC50 = 0.3981 nM
|
|
|
| 2 |
IC50 = 63.1 nM
|
|
|
|
CP0542749
|
(R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-cyclopropylmethanol
Show/Hide
|
C22H25FN2O
|
2
|
| 1 |
EC50 = 0.5012 nM
|
|
|
| 2 |
IC50 = 1995.26 nM
|
|
|
|
CP0542748
|
(S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-naphthalen-2-ylmethanol
Show/Hide
|
C29H27FN2O
|
2
|
| 1 |
EC50 = 1.585 nM
|
|
|
| 2 |
IC50 = 31.62 nM
|
|
|
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CP0008077
|
(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
Show/Hide
|
C22H29FO5
|
4
|
| 1 |
EC50 = 1.995 nM
|
|
|
| 2 |
EC50 = 3.162 nM
|
|
|
| 3 |
IC50 = 1.259 nM
|
|
|
| 4 |
IC50 = 6.31 nM
|
|
|
|
CP0444612
|
(1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-phenylethanol
Show/Hide
|
C26H27FN2O
|
2
|
| 1 |
EC50 = 3.981 nM
|
|
|
| 2 |
IC50 = 7.943 nM
|
|
|
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CP0479625
|
(1R)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-thiophen-3-ylethanol
Show/Hide
|
C24H25FN2OS
|
2
|
| 1 |
EC50 = 3.981 nM
|
|
|
| 2 |
IC50 = 6.31 nM
|
|
|
|
CP0419138
|
(1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-(3,4-difluoro-5-methoxyphenyl)ethanol
Show/Hide
|
C27H27F3N2O2
|
2
|
| 1 |
EC50 = 6.31 nM
|
|
|
| 2 |
IC50 = 1.995 nM
|
|
|
|
CP0419132
|
(R)-(3,4-difluoro-5-methoxyphenyl)-[(5S)-1-(4-methoxyphenyl)-4,4a,5,6,7,8-hexahydrobenzo[f]indazol-5-yl]methanol
Show/Hide
|
C26H26F2N2O3
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
IC50 = 3.162 nM
|
|
|
|
CP0039831
|
(1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl]-1-(4-fluorophenyl)ethan-1-ol
Show/Hide
|
C26H26F2N2O
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
IC50 = 5.012 nM
|
|
|
|
CP0542750
|
(S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-phenylmethanol
Show/Hide
|
C25H25FN2O
|
2
|
| 1 |
EC50 = 25.12 nM
|
|
|
| 2 |
IC50 = 3981.07 nM
|
|
|
|
CP0569041
|
(1R)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]ethanol
Show/Hide
|
C20H23FN2O
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
IC50 = 0.3162 nM
|
|
|
|
CP0569042
|
[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]methanol
Show/Hide
|
C19H21FN2O
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
IC50 = 5.012 nM
|
|
|
|
CP0043410
|
(R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl](3,4-difluoro-5-methoxyphenyl)methanol
Show/Hide
|
C26H25F3N2O2
|
2
|
| 1 |
EC50 = 63.1 nM
|
|
|
| 2 |
IC50 = 15.85 nM
|
|
|
|
CP0273275
|
2-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl]propan-2-ol
Show/Hide
|
C21H25FN2O
|
2
|
| 1 |
EC50 = 63.1 nM
|
|
|
| 2 |
IC50 = 39.81 nM
|
|
|
|
CP0297207
|
(1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl]ethan-1-ol
Show/Hide
|
C20H23FN2O
|
4
|
| 1 |
EC50 = 63.1 nM
|
|
|
| 2 |
EC50 = 2511.89 nM
|
|
|
| 3 |
IC50 = 6.31 nM
|
|
|
| 4 |
IC50 = 63.1 nM
|
|
|
|
CP0101543
|
(R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl](phenyl)methanol
Show/Hide
|
C25H25FN2O
|
4
|
| 1 |
EC50 = 63.1 nM
|
|
|
| 2 |
EC50 = 100 nM
|
|
|
| 3 |
IC50 = 19.95 nM
|
|
|
| 4 |
IC50 = 39.81 nM
|
|
|
|
CP0043529
|
(R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl](4-fluorophenyl)methanol
Show/Hide
|
C25H24F2N2O
|
2
|
| 1 |
EC50 = 79.43 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
|
CP0419142
|
2-[(4aR,5S)-1-(4-methoxyphenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]propan-2-ol
Show/Hide
|
C22H28N2O2
|
2
|
| 1 |
EC50 = 79.43 nM
|
|
|
| 2 |
IC50 = 2511.89 nM
|
|
|
|
CP0038098
|
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
Show/Hide
|
C21H30O5
|
4
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
EC50 = 2511.89 nM
|
|
|
| 3 |
IC50 = 25.12 nM
|
|
|
| 4 |
IC50 = 316.23 nM
|
|
|
|
CP0419139
|
(R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl](thiophen-3-yl)methanol
Show/Hide
|
C23H23FN2OS
|
2
|
| 1 |
EC50 = 125.89 nM
|
|
|
| 2 |
IC50 = 5.012 nM
|
|
|
|
CP0534386
|
(1R)-1-[(4aR,5S)-1-(4-methoxyphenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-(4-fluorophenyl)ethanol
Show/Hide
|
C27H29FN2O2
|
2
|
| 1 |
EC50 = 125.89 nM
|
|
|
| 2 |
IC50 = 251.19 nM
|
|
|
|
CP0494242
|
(1S)-1-[(4aR,5S)-1-(4-methoxyphenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]ethanol
Show/Hide
|
C21H26N2O2
|
2
|
| 1 |
EC50 = 251.19 nM
|
|
|
| 2 |
IC50 = 0.1585 nM
|
|
|
|
CP0544223
|
(R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(2,3,4,5,6-pentafluorophenyl)methanol
Show/Hide
|
C25H20F6N2O
|
2
|
| 1 |
EC50 = 251.19 nM
|
|
|
| 2 |
IC50 = 31.62 nM
|
|
|
|
CP0419137
|
(1R)-1-[(4aR,5S)-4a-methyl-1-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-(4-fluorophenyl)ethanol
Show/Hide
|
C27H29FN2O
|
2
|
| 1 |
EC50 = 316.23 nM
|
|
|
| 2 |
IC50 = 630.96 nM
|
|
|
|
CP0544640
|
(R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-naphthalen-2-ylmethanol
Show/Hide
|
C29H27FN2O
|
2
|
| 1 |
EC50 = 630.96 nM
|
|
|
| 2 |
IC50 = 398.11 nM
|
|
|
|
CP0215797
|
(1R)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl]-2,2-dimethylpropan-1-ol
Show/Hide
|
C23H29FN2O
|
2
|
| 1 |
EC50 = 794.33 nM
|
|
|
| 2 |
IC50 = 0.2512 nM
|
|
|
|
CP0544222
|
(S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-cyclopropylmethanol
Show/Hide
|
C22H25FN2O
|
2
|
| 1 |
EC50 = 1000 nM
|
|
|
| 2 |
IC50 = 31.62 nM
|
|
|
|
CP0451143
|
(1R)-1-[(4aR,5S)-4a-methyl-1-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-phenylethanol
Show/Hide
|
C27H30N2O
|
2
|
| 1 |
EC50 = 1258.93 nM
|
|
|
| 2 |
IC50 = 31.62 nM
|
|
|
|
CP0451116
|
(1S)-1-[(4aR,5S)-4a-methyl-1-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]ethanol
Show/Hide
|
C21H26N2O
|
2
|
| 1 |
EC50 = 1584.89 nM
|
|
|
| 2 |
IC50 = 0.1995 nM
|
|
|
|
CP0548123
|
(1R)-1-[(4aR,5S)-4a-methyl-1-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-thiophen-3-ylethanol
Show/Hide
|
C25H28N2OS
|
2
|
| 1 |
EC50 = 1584.89 nM
|
|
|
| 2 |
IC50 = 100 nM
|
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|
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CP0542746
|
(1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-2-methylpropan-1-ol
Show/Hide
|
C22H27FN2O
|
2
|
| 1 |
EC50 = 1584.89 nM
|
|
|
| 2 |
IC50 = 0.631 nM
|
|
|
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CP0542747
|
(1R)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-2-methylpropan-1-ol
Show/Hide
|
C22H27FN2O
|
2
|
| 1 |
EC50 = 1584.89 nM
|
|
|
| 2 |
IC50 = 158.49 nM
|
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|
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CP0444609
|
(1R)-1-(3,4-difluoro-5-methoxyphenyl)-1-[(5S)-1-(4-methylphenyl)-4,4a,5,6,7,8-hexahydrobenzo[f]indazol-5-yl]ethanol
Show/Hide
|
C27H28F2N2O2
|
2
|
| 1 |
EC50 = 1995.26 nM
|
|
|
| 2 |
IC50 = 7.943 nM
|
|
|
|
CP0562629
|
(S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(2,3,4,5,6-pentafluorophenyl)methanol
Show/Hide
|
C25H20F6N2O
|
2
|
| 1 |
EC50 = 1995.26 nM
|
|
|
| 2 |
IC50 = 25.12 nM
|
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|
|
CP0444613
|
(3S)-3-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-3-hydroxypropanenitrile
Show/Hide
|
C21H22FN3O
|
2
|
| 1 |
EC50 = 2511.89 nM
|
|
|
| 2 |
IC50 = 1584.89 nM
|
|
|
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CP0544224
|
(1R)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]propan-1-ol
Show/Hide
|
C21H25FN2O
|
2
|
| 1 |
EC50 = 2511.89 nM
|
|
|
| 2 |
IC50 = 15.85 nM
|
|
|
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CP0542744
|
(S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-cyclopentylmethanol
Show/Hide
|
C24H29FN2O
|
2
|
| 1 |
EC50 = 3162.28 nM
|
|
|
| 2 |
IC50 = 398.11 nM
|
|
|
|
CP0419153
|
(1R)-1-[(4aR,5S)-1-(4-methoxyphenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-phenylethanol
Show/Hide
|
C27H30N2O2
|
2
|
| 1 |
EC50 = 5011.87 nM
|
|
|
| 2 |
IC50 = 501.19 nM
|
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|
|
CP0419141
|
(R)-[(4aR,5S)-4a-methyl-1-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-thiophen-3-ylmethanol
Show/Hide
|
C24H26N2OS
|
2
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
IC50 = 39.81 nM
|
|
|
|
CP0419172
|
(1R)-1-[(4aR,5S)-1-(4-methoxyphenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-(3,4-difluoro-5-methoxyphenyl)ethanol
Show/Hide
|
C28H30F2N2O3
|
2
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
IC50 = 1258.93 nM
|
|
|
|
CP0444611
|
(1R)-1-[(4aR,5S)-1-(4-methoxyphenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-thiophen-3-ylethanol
Show/Hide
|
C25H28N2O2S
|
2
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
IC50 = 1584.89 nM
|
|
|
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CP0451115
|
(R)-[(4aR,5S)-1-(4-methoxyphenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-phenylmethanol
Show/Hide
|
C26H28N2O2
|
2
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
IC50 = 1258.93 nM
|
|
|
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CP0451118
|
(R)-[(4aR,5S)-4a-methyl-1-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-phenylmethanol
Show/Hide
|
C26H28N2O
|
2
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
IC50 = 398.11 nM
|
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|
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CP0487470
|
(R)-[(4aR,5S)-1-(4-methoxyphenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-thiophen-3-ylmethanol
Show/Hide
|
C24H26N2O2S
|
2
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
IC50 = 501.19 nM
|
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|
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CP0562628
|
(1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]propan-1-ol
Show/Hide
|
C21H25FN2O
|
2
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
IC50 = 19.95 nM
|
|
|
|
CP0534036
|
(R)-[(4aR,5S)-1-(4-methoxyphenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(4-fluorophenyl)methanol
Show/Hide
|
C26H27FN2O2
|
2
|
| 1 |
EC50 = 15848.93 nM
|
|
|
| 2 |
IC50 = 79.43 nM
|
|
|
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CP0451125
|
(R)-[(4aR,5S)-4a-methyl-1-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(4-fluorophenyl)methanol
Show/Hide
|
C26H27FN2O
|
2
|
| 1 |
EC50 = 31622.78 nM
|
|
|
| 2 |
IC50 = 251.19 nM
|
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|
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CP0451104
|
(R)-[(4aR,5S)-4a-methyl-1-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(3,4-difluoro-5-methoxyphenyl)methanol
Show/Hide
|
C27H28F2N2O2
|
2
|
| 1 |
EC50 = 100000 nM
|
|
|
| 2 |
IC50 = 158.49 nM
|
|
|
