Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-2-methylpropan-1-ol
    Show/Hide
 PubChem ID
CID: 168288595
Canonical SMILES
CC(C)[C@@H](O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1
    Show/Hide
Compound Formula C22H27FN2O
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P06536
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000230 INS-1 832/13
 Cell Line Info 
Rattus norvegicus (Rat)  2
1
EC50 = 1584.89 nM
   TI
   LI
   LO
   TS
2
IC50 = 158.49 nM
   TI
   LI
   LO
   TS