Brief Information of the Compound and Protein
Compound Name
(1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl]-1-(4-fluorophenyl)ethan-1-ol
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PubChem ID
CID: 11281576
SID: 16368514
Canonical SMILES
C[C@](O)([C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)c1ccc(F)cc1
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Compound Formula C26H26F2N2O
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P06536
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000230 INS-1 832/13 Rattus norvegicus (Rat)  2
1
EC50 = 15.85 nM
   TI
   LI
   LO
   TS
2
IC50 = 5.012 nM
   TI
   LI
   LO
   TS