| Compound ID |
Compound Name |
Compound Formula |
|
CP0420411
|
THC, 11-OH-delta 8
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|
C25H38O3
|
1
|
| 1 |
EC50 = 0.73 nM
|
|
|
|
CP0546704
|
[4-(3-carbamoylphenyl)phenyl] N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]carbamate
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|
C27H28Cl2N4O3
|
1
|
| 1 |
EC50 = 0.9 nM
|
|
|
|
CP0862246
|
[4-(3-Carbamoylphenyl)phenyl]N-[4-[4-(2-Methoxyphenyl)-piperazin-1-yl]butyl]carbamate Hydrochloride
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|
C29H35ClN4O4
|
1
|
| 1 |
EC50 = 0.9 nM
|
|
|
|
CP0420406
|
[4-(3-carbamoylphenyl)phenyl] N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C28H30Cl2N4O3
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0437064
|
[3-(3-carbamoylphenyl)phenyl] N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]carbamate
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|
C27H28Cl2N4O3
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0510298
|
[(6aR,10aR)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,8,10a-tetrahydrobenzo[c]chromen-9-yl]methanol
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|
C25H38O2
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0511758
|
(3-methoxy-4-phenylphenyl) N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C28H31Cl2N3O3
|
1
|
| 1 |
EC50 = 1.66 nM
|
|
|
|
CP0036921
|
3-HYDROXYTYRAMINE HYDROCHLORIDE
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|
C8H11NO2
|
3
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
EC50 = 2.9 nM
|
|
|
| 3 |
EC50 = 6.4 nM
|
|
|
|
CP0463999
|
[3-(3-carbamoylphenyl)phenyl] N-[3-(4-phenylpiperazin-1-yl)propyl]carbamate
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|
C27H30N4O3
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0006107
|
CAS_85760-74-3
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|
C13H21N3
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0418423
|
(6-chloro-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0408057
|
[4-(3-carbamoylphenyl)phenyl] N-[4-(4-phenylpiperazin-1-yl)butyl]carbamate
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|
C28H32N4O3
|
1
|
| 1 |
EC50 = 3.6 nM
|
|
|
|
CP0408059
|
(3-fluoro-4-phenylphenyl) N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C27H28Cl2FN3O2
|
1
|
| 1 |
EC50 = 3.7 nM
|
|
|
|
CP0477672
|
[3-(3-carbamoylphenyl)phenyl] N-[4-(4-phenylpiperazin-1-yl)butyl]carbamate
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|
C28H32N4O3
|
1
|
| 1 |
EC50 = 3.7 nM
|
|
|
|
CP0546706
|
[4-(3-carbamoylphenyl)-3-methoxyphenyl] N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]carbamate
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|
C30H36N4O5
|
1
|
| 1 |
EC50 = 3.9 nM
|
|
|
|
CP0546705
|
[4-(3-carbamoylphenyl)phenyl] N-[4-[4-(2-methylphenyl)piperazin-1-yl]butyl]carbamate
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|
C29H34N4O3
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0412102
|
(6-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C21H24N4O2
|
1
|
| 1 |
EC50 = 4.3 nM
|
|
|
|
CP0463998
|
[4-(3-carbamoylphenyl)-3-methoxyphenyl] N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C29H32Cl2N4O4
|
1
|
| 1 |
EC50 = 4.4 nM
|
|
|
|
CP0439996
|
(4-chloro-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 4.4 nM
|
|
|
|
CP0421088
|
[4-[2-(5-chloropyridin-3-yl)oxyethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
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|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0127400
|
(-)-Pramipexole
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|
C10H17N3S
|
2
|
| 1 |
EC50 = 5.4 nM
|
|
|
| 2 |
Ki = 2.78 nM
|
|
|
|
CP0847329
|
Phenyl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C21H25Cl2N3O2
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
|
CP0472959
|
(6-methoxy-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 6.4 nM
|
|
|
|
CP0420412
|
[3-(3-carbamoylphenyl)phenyl] N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C28H30Cl2N4O3
|
1
|
| 1 |
EC50 = 6.5 nM
|
|
|
|
CP0848421
|
4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butylcarbamoyloxy]naphthalene-1-carboxylic acid hydrochloride
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|
C26H28Cl3N3O4
|
1
|
| 1 |
EC50 = 6.6 nM
|
|
|
|
CP0847327
|
(4-carbamoyl-1-naphthyl)-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
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|
C26H29Cl3N4O3
|
1
|
| 1 |
EC50 = 6.8 nM
|
|
|
|
CP0885396
|
1H-indol-4-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C23H26Cl2N4O2
|
1
|
| 1 |
EC50 = 6.9 nM
|
|
|
|
CP0437065
|
[4-(3-carbamoylphenyl)-3-fluorophenyl] N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]carbamate
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|
C28H27Cl2FN4O3
|
1
|
| 1 |
EC50 = 6.9 nM
|
|
|
|
CP0434180
|
(4-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 6.9 nM
|
|
|
|
CP0421087
|
1H-indol-2-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C20H22N4O2
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0904712
|
1-naphthyl N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]carbamate
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|
C24H25Cl2N3O2
|
1
|
| 1 |
EC50 = 7.4 nM
|
|
|
|
CP0437066
|
[4-(3-carbamoylphenyl)phenyl] N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]carbamate
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|
C28H32N4O4
|
1
|
| 1 |
EC50 = 7.4 nM
|
|
|
|
CP0847330
|
1H-benzimidazol-4-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
Show/Hide
|
C22H26Cl3N5O2
|
1
|
| 1 |
EC50 = 7.5 nM
|
|
|
|
CP0434162
|
1H-indol-2-yl-[4-(2-phenoxyethyl)piperazin-1-yl]methanone
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|
C21H23N3O2
|
1
|
| 1 |
EC50 = 9.2 nM
|
|
|
|
CP0129619
|
N-[3-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]-3-hydroxycyclobutyl]naphthalene-2-carboxamide
Show/Hide
|
C27H34N4O2S
|
1
|
| 1 |
EC50 = 9.3 nM
|
|
|
|
CP0434181
|
(1-methylindol-3-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C21H24N4O2
|
1
|
| 1 |
EC50 = 9.5 nM
|
|
|
|
CP0045801
|
(10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
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|
C21H30O2
|
1
|
| 1 |
EC50 = 10.2 nM
|
|
|
|
CP0885395
|
1-naphthyl N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]carbamate
Show/Hide
|
C25H29N3O3
|
1
|
| 1 |
EC50 = 10.5 nM
|
|
|
|
CP0463992
|
[4-(3-carbamoylphenyl)phenyl] N-[4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]carbamate
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|
C29H31F3N4O3
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0848419
|
(4-hydroxy-1-naphthyl)-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
Show/Hide
|
C25H28Cl3N3O3
|
1
|
| 1 |
EC50 = 11.2 nM
|
|
|
|
CP0885397
|
Benzothiophen-4-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
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|
C23H26Cl3N3O2S
|
1
|
| 1 |
EC50 = 11.4 nM
|
|
|
|
CP0464005
|
9H-carbazol-2-yl N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]carbamate
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|
C28H32N4O3
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0434161
|
(5-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0421085
|
1-benzothiophen-2-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H21N3O2S
|
1
|
| 1 |
EC50 = 13.3 nM
|
|
|
|
CP0382956
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 13.5 nM
|
|
|
|
CP0408056
|
[3-(3-carbamoylphenyl)phenyl] N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C29H34N4O4
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0862245
|
(4-Phenylphenyl)N-[3-[4-(2-Methoxyphenyl)piperazin-1-yl]-propyl]carbamate Hydrochloride
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|
C27H32ClN3O3
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0848403
|
2,3-dihydro-1,4-benzodioxin-5-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
Show/Hide
|
C23H28Cl3N3O4
|
1
|
| 1 |
EC50 = 14.1 nM
|
|
|
|
CP0847328
|
1-naphthyl N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C26H31N3O3
|
1
|
| 1 |
EC50 = 14.4 nM
|
|
|
|
CP0463995
|
(4-phenylphenyl) N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]carbamate
Show/Hide
|
C26H27Cl2N3O2
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0472960
|
(4-methoxyphenyl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0711830
|
(4-Phenylphenyl)N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]carbamate Hydrochloride
Show/Hide
|
C27H30Cl3N3O2
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0437063
|
[4-(3-carbamoylphenyl)-3-fluorophenyl] N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C28H29Cl2FN4O3
|
1
|
| 1 |
EC50 = 18.6 nM
|
|
|
|
CP0420413
|
[3-(3-carbamoylphenyl)phenyl] N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]carbamate
Show/Hide
|
C28H32N4O4
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0848420
|
1-naphthyl N-[3-[4-(o-tolyl)piperazin-1-yl]propyl]carbamate hydrochloride
Show/Hide
|
C25H30ClN3O2
|
1
|
| 1 |
EC50 = 19.2 nM
|
|
|
|
CP0885398
|
Tetralin-1-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C25H31Cl2N3O2
|
1
|
| 1 |
EC50 = 20.6 nM
|
|
|
|
CP0137322
|
1H-indol-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O3
|
2
|
| 1 |
EC50 = 21 nM
|
|
|
| 2 |
EC50 = 38 nM
|
|
|
|
CP0904711
|
1-naphthyl N-[4-[4-(o-tolyl)piperazin-1-yl]butyl]carbamate hydrochloride
Show/Hide
|
C26H32ClN3O2
|
1
|
| 1 |
EC50 = 21.7 nM
|
|
|
|
CP0891460
|
(4-methoxy-1-naphthyl)-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
Show/Hide
|
C26H30Cl3N3O3
|
1
|
| 1 |
EC50 = 25.4 nM
|
|
|
|
CP0412156
|
(7-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 25.7 nM
|
|
|
|
CP0439997
|
[4-[2-(4-chlorophenoxy)propyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C22H24ClN3O2
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0412251
|
1H-benzimidazol-2-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0437975
|
(7-chloro-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0491760
|
1H-indol-2-yl-[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O3
|
1
|
| 1 |
EC50 = 33.8 nM
|
|
|
|
CP0420409
|
(3-methoxy-4-phenylphenyl) N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C29H35N3O4
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0439995
|
(1-methylindol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 37.6 nM
|
|
|
|
CP0891459
|
(4-fluoro-1-naphthyl)-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
Show/Hide
|
C25H27Cl3FN3O2
|
1
|
| 1 |
EC50 = 37.7 nM
|
|
|
|
CP0408058
|
[4-(3-carbamoylphenyl)phenyl] N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]carbamate
Show/Hide
|
C28H28Cl2N4O3
|
1
|
| 1 |
EC50 = 37.8 nM
|
|
|
|
CP0443819
|
[4-[2-(2-chloro-4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C22H24ClN3O3
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0434144
|
1-benzofuran-2-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H21N3O3
|
1
|
| 1 |
EC50 = 42 nM
|
|
|
|
CP0418431
|
1H-indazol-3-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0434177
|
[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0951983
|
1-naphthyl N-[3-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]carbamate
Show/Hide
|
C25H26F3N3O2
|
1
|
| 1 |
EC50 = 57.8 nM
|
|
|
|
CP0434179
|
(5-methoxy-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 59 nM
|
|
|
|
CP0422653
|
1H-indol-2-yl-[4-[2-(1H-indol-5-yloxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
EC50 = 60.9 nM
|
|
|
|
CP0412250
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrolo[3,2-c]pyridin-2-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0897138
|
Tetralin-5-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C25H31Cl2N3O2
|
1
|
| 1 |
EC50 = 76.5 nM
|
|
|
|
CP0412249
|
(3-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0382983
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrolo[2,3-c]pyridin-2-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 81 nM
|
|
|
|
CP0412108
|
1H-indol-2-yl-[4-[2-(4-methoxyphenoxy)propyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 = 82 nM
|
|
|
|
CP0382979
|
[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C21H26N2O4
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0434182
|
(5-chloro-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0418425
|
[4-[2-(4-bromophenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C21H22BrN3O2
|
1
|
| 1 |
EC50 = 105 nM
|
|
|
|
CP0421086
|
[4-[2-(4-chlorophenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C21H22ClN3O2
|
1
|
| 1 |
EC50 = 114 nM
|
|
|
|
CP0463489
|
[4-[2-(4-chloro-3-methylphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C22H24ClN3O2
|
1
|
| 1 |
EC50 = 114 nM
|
|
|
|
CP0422654
|
(4-methoxyphenyl)-[4-(2-phenoxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H24N2O3
|
1
|
| 1 |
EC50 = 115 nM
|
|
|
|
CP0472958
|
(4-methoxy-2-methylphenyl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H25N3O3
|
1
|
| 1 |
EC50 = 116 nM
|
|
|
|
CP0463486
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrol-2-yl)methanone
Show/Hide
|
C16H20N4O2
|
1
|
| 1 |
EC50 = 118 nM
|
|
|
|
CP0437062
|
9H-carbazol-2-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C27H28Cl2N4O2
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0418424
|
[4-[2-(4-fluorophenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C21H22FN3O2
|
1
|
| 1 |
EC50 = 126 nM
|
|
|
|
CP0569769
|
(4-phenylphenyl) N-[4-[4-(2-methylphenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C28H33N3O2
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0418430
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(6-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0510296
|
9H-carbazol-2-yl N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]carbamate
Show/Hide
|
C26H26Cl2N4O2
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0422652
|
1H-indol-2-yl-[4-[2-(4-methylphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
EC50 = 151 nM
|
|
|
|
CP0382982
|
(6-methoxy-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
EC50 = 155 nM
|
|
|
|
CP0382958
|
(4-chloro-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24ClN3O3
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0434173
|
[4-[2-(4-methoxyphenoxy)propyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O4
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0001212
|
1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
Show/Hide
|
C23H29N5OS
|
2
|
| 1 |
EC50 = 166.7 nM
|
|
|
| 2 |
IC50 = 8.7 nM
|
|
|
|
CP0472954
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 167 nM
|
|
|
|
CP0412154
|
1H-benzimidazol-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 192 nM
|
|
|
|
CP0472979
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrolo[3,2-b]pyridin-2-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0418429
|
1H-indol-5-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O3
|
1
|
| 1 |
EC50 = 208 nM
|
|
|
|
CP0418416
|
1H-indol-3-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O3
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0472957
|
(6-chloro-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24ClN3O3
|
1
|
| 1 |
EC50 = 225 nM
|
|
|
|
CP0862247
|
[3-(3-Carbamoylphenyl)phenyl]N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]carbamate Hydrochloride
Show/Hide
|
C27H30Cl3N3O2
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0422664
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(4-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 = 266 nM
|
|
|
|
CP0434155
|
[4-[2-(2-methoxyphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C21H26N2O4
|
1
|
| 1 |
EC50 = 278 nM
|
|
|
|
CP0434157
|
[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[3,2-c]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0434159
|
(5-methoxy-1H-indol-2-yl)-[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
EC50 = 284 nM
|
|
|
|
CP0412093
|
1H-benzimidazol-2-yl-[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 285 nM
|
|
|
|
CP0412157
|
[4-[2-(1,3-benzodioxol-5-yloxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C22H23N3O4
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0412099
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1-methylindol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0422660
|
[4-[2-(1,3-benzodioxol-5-yloxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C21H24N2O5
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0869065
|
(4-Phenylphenyl)N-[4-[4-(2-Methoxyphenyl)piperazin-1-yl]-butyl]carbamate Hydrochloride
Show/Hide
|
C28H34ClN3O3
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0412090
|
(4-methoxy-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
EC50 = 411 nM
|
|
|
|
CP0412155
|
1-benzofuran-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24N2O4
|
1
|
| 1 |
EC50 = 430 nM
|
|
|
|
CP0472956
|
1H-indol-2-yl-[4-(2-pyridin-4-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
EC50 = 472 nM
|
|
|
|
CP0439994
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(7-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 = 473 nM
|
|
|
|
CP0434156
|
[4-[2-(4-methoxyphenoxy)ethyl]-2-methylpiperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O4
|
1
|
| 1 |
EC50 = 510 nM
|
|
|
|
CP0434200
|
(5-methoxy-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
|
CP0382981
|
(4-ethylphenyl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0412158
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C20H24N2O3
|
1
|
| 1 |
EC50 = 548 nM
|
|
|
|
CP0418417
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(3-methoxyphenyl)methanone
Show/Hide
|
C21H26N2O4
|
1
|
| 1 |
EC50 = 550 nM
|
|
|
|
CP0422656
|
(7-chloro-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24ClN3O3
|
1
|
| 1 |
EC50 = 563 nM
|
|
|
|
CP0470714
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[3,2-c]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 576 nM
|
|
|
|
CP0463488
|
[4-[2-(3,4-dimethylphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
EC50 = 610 nM
|
|
|
|
CP0460936
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(5-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 = 611 nM
|
|
|
|
CP0434164
|
1H-indol-2-yl-[4-[2-(4-methylsulfanylphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O2S
|
1
|
| 1 |
EC50 = 630 nM
|
|
|
|
CP0565517
|
(6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,8,10a-tetrahydrobenzo[c]chromene
Show/Hide
|
C22H32O
|
1
|
| 1 |
EC50 = 667 nM
|
|
|
|
CP0382963
|
MLS001173843
Show/Hide
|
C21H26N2O4
|
1
|
| 1 |
EC50 = 710 nM
|
|
|
|
CP0463487
|
[4-[2-(3,4-dimethoxyphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
EC50 = 710 nM
|
|
|
|
CP0402333
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[2,3-c]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 810 nM
|
|
|
|
CP0384679
|
N-(3-methylphenyl)-3-(4-pyridin-2-ylpiperidin-1-yl)propanamide
Show/Hide
|
C20H25N3O
|
2
|
| 1 |
EC50 = 970 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0556582
|
(7-methoxy-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
EC50 = 980 nM
|
|
|
|
CP0412107
|
[4-[2-(3-chloro-4-methylphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C22H24ClN3O2
|
1
|
| 1 |
EC50 = 997 nM
|
|
|
|
CP0415799
|
[4-[2-(4-chlorophenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C20H23ClN2O3
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0420408
|
(4-phenylphenyl) N-[4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]carbamate
Show/Hide
|
C28H30F3N3O2
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0479729
|
1H-indol-2-yl-[4-[2-(4-nitrophenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C21H22N4O4
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0382957
|
[4-[2-(4-ethylphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0384372
|
N-(3-methylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propanamide
Show/Hide
|
C19H24N4O
|
2
|
| 1 |
EC50 = 1601 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0421090
|
1H-indol-2-yl-[4-[2-(4-methoxy-N-methylanilino)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0472980
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(3-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0460935
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(5-methoxypyridin-2-yl)methanone
Show/Hide
|
C20H25N3O4
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0434171
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(2-methoxyphenyl)methanone
Show/Hide
|
C21H26N2O4
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0382985
|
[4-[2-(4-ethylphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0384370
|
N-(3-ethylphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C19H24N4O
|
2
|
| 1 |
EC50 = 2755 nM
|
|
|
| 2 |
IC50 = 88205 nM
|
|
|
|
CP0472955
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[3,2-b]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0384381
|
N-pyridin-3-yl-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C16H19N5O
|
1
|
| 1 |
EC50 = 2802 nM
|
|
|
|
CP0422651
|
(5-chloro-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24ClN3O3
|
1
|
| 1 |
EC50 = 2900 nM
|
|
|
|
CP0412091
|
1-benzothiophen-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24N2O3S
|
1
|
| 1 |
EC50 = 3300 nM
|
|
|
|
CP0437980
|
1H-indol-2-yl-[4-(2-pyridin-2-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
EC50 = 3500 nM
|
|
|
|
CP0412252
|
1H-indol-2-yl-[4-[2-[4-(trifluoromethoxy)phenoxy]ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H22F3N3O3
|
1
|
| 1 |
EC50 = 3800 nM
|
|
|
|
CP0491767
|
[4-[2-(4-methoxyphenoxy)ethyl]-3-methylpiperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O4
|
1
|
| 1 |
EC50 = 4400 nM
|
|
|
|
CP0384667
|
N-(3-methylphenyl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C17H21N5O
|
2
|
| 1 |
EC50 = 5581 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0384672
|
N-(3-methylphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C18H22N4O
|
2
|
| 1 |
EC50 = 6354 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0382960
|
[4-[1-(4-methoxyphenoxy)propan-2-yl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O4
|
1
|
| 1 |
EC50 = 9300 nM
|
|
|
|
CP0402377
|
1-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]ethanone
Show/Hide
|
C15H22N2O3
|
1
|
| 1 |
EC50 = 9700 nM
|
|
|
|
CP0422650
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-pyridin-4-ylmethanone
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
EC50 = 22000 nM
|
|
|
|
CP0418422
|
cyclohexyl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C20H30N2O3
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0384374
|
2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-yl)-N-(m-tolyl)acetamide
Show/Hide
|
C19H23N3O
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0382961
|
[4-[2-(4-ethoxyphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0379280
|
2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C28H30N4O4S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0008601
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
Show/Hide
|
C21H23ClFNO2
|
4
|
| 1 |
IC50 = 0.25 nM
|
|
|
| 2 |
Ki = 0.96 nM
|
|
|
| 3 |
Ki = 2.2 nM
|
|
|
| 4 |
Ki = 6.4 nM
|
|
|
|
CP0163132
|
(+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol
Show/Hide
|
C25H31NO
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0224658
|
8-chloro-7-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H26ClFN2O4
|
1
|
| 1 |
IC50 = 24.8 nM
|
|
|
|
CP0003459
|
3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H37N5OS
|
1
|
| 1 |
IC50 = 41.4 nM
|
|
|
|
CP0040671
|
8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C23H26FN3O2
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0089932
|
N-[4-[4-(3-methylphenyl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C24H29N3O2
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0398640
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-2-sulfonamide
Show/Hide
|
C24H29N3O2S
|
1
|
| 1 |
IC50 = 248 nM
|
|
|
|
CP0057840
|
US8748608, 34
Show/Hide
|
C23H26Cl2N4O2
|
1
|
| 1 |
IC50 = 495 nM
|
|
|
|
CP0042262
|
N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
Show/Hide
|
C15H23N3O4S
|
2
|
| 1 |
IC50 = 560 nM
|
|
|
| 2 |
Kd = 39.81 nM
|
|
|
|
CP0207472
|
N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-pyridin-2-ylbenzamide
Show/Hide
|
C27H31FN4O2
|
1
|
| 1 |
IC50 = 699 nM
|
|
|
|
CP0417851
|
N-benzyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C28H29N3O2S
|
1
|
| 1 |
IC50 = 943 nM
|
|
|
|
CP0416325
|
N-ethyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C23H27N3O2S
|
1
|
| 1 |
IC50 = 1171 nM
|
|
|
|
CP0398637
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-1-sulfonamide
Show/Hide
|
C24H29N3O2S
|
1
|
| 1 |
IC50 = 1195 nM
|
|
|
|
CP0258057
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
|
C23H25Cl2FN4O
|
1
|
| 1 |
IC50 = 1220 nM
|
|
|
|
CP0207473
|
N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methoxy-1-benzofuran-2-carboxamide
Show/Hide
|
C25H30FN3O4
|
1
|
| 1 |
IC50 = 1240 nM
|
|
|
|
CP0416326
|
N-(cyclopropylmethyl)-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H29N3O2S
|
1
|
| 1 |
IC50 = 1426 nM
|
|
|
|
CP0419036
|
N,N-dimethyl-2-(3-naphthalen-1-ylsulfonylpyrrolo[2,3-b]pyridin-1-yl)ethanamine
Show/Hide
|
C21H21N3O2S
|
1
|
| 1 |
IC50 = 1558 nM
|
|
|
|
CP0377208
|
N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C21H23N3O2S
|
1
|
| 1 |
IC50 = 2102 nM
|
|
|
|
CP0377202
|
N-methyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C22H25N3O2S
|
1
|
| 1 |
IC50 = 2416 nM
|
|
|
|
CP0487098
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propylnaphthalene-2-sulfonamide
Show/Hide
|
C24H29N3O2S
|
1
|
| 1 |
IC50 = 2508 nM
|
|
|
|
CP0417858
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylbenzenesulfonamide
Show/Hide
|
C20H27N3O2S
|
1
|
| 1 |
IC50 = 2893 nM
|
|
|
|
CP0273714
|
N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methoxy-1H-indole-2-carboxamide
Show/Hide
|
C25H31FN4O3
|
1
|
| 1 |
IC50 = 2990 nM
|
|
|
|
CP0294038
|
N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C24H28FN3O2S
|
1
|
| 1 |
IC50 = 3210 nM
|
|
|
|
CP0038047
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C23H24Cl2FN3OS
|
1
|
| 1 |
IC50 = 3770 nM
|
|
|
|
CP0384369
|
2-(4-phenylpiperidin-1-yl)-N-(m-tolyl)acetamide
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0384371
|
N-(3-methylphenyl)-3-(4-pyrimidin-2-ylpiperazin-1-yl)propanamide
Show/Hide
|
C18H23N5O
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0380100
|
2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)-N,N-dimethylethanamine
Show/Hide
|
C17H18FN3O2S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0405688
|
2-[3-(3-chlorophenyl)sulfonylpyrrolo[2,3-b]pyridin-1-yl]-N,N-dimethylethanamine
Show/Hide
|
C17H18ClN3O2S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0424416
|
2-[3-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-yl]ethylamine
Show/Hide
|
C15H15N3O2S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0439248
|
2-{3-[(3-Chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine
Show/Hide
|
C15H14ClN3O2S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0392694
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]quinazolin-4-amine
Show/Hide
|
C26H33N5
|
1
|
| 1 |
Ki = 0.02 nM
|
|
|
|
CP0179022
|
2-[4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]-1,3-oxazole
Show/Hide
|
C28H28F3N5OS
|
1
|
| 1 |
Ki = 0.06761 nM
|
|
|
|
CP0375682
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
|
C25H39N3O
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0398326
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C26H28F3N5OS
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0380643
|
2-[3-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]-1,3-oxazole
Show/Hide
|
C28H28F3N5OS
|
1
|
| 1 |
Ki = 0.182 nM
|
|
|
|
CP0414727
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[3-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7S
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0507029
|
1-[4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]ethanone
Show/Hide
|
C27H29F3N4OS
|
1
|
| 1 |
Ki = 0.2089 nM
|
|
|
|
CP0384669
|
(4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
|
C15H21NO2
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0511219
|
4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
|
C15H21NO2
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0507041
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzonitrile
Show/Hide
|
C26H26F3N5S
|
1
|
| 1 |
Ki = 0.263 nM
|
|
|
|
CP0410018
|
(2R,3S)-5-[3-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C25H33F3N4S
|
1
|
| 1 |
Ki = 0.2754 nM
|
|
|
|
CP0414387
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[3-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7OS
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0445670
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzenesulfonamide
Show/Hide
|
C25H28F3N5O2S2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0214556
|
5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxamide
Show/Hide
|
C25H27F3N6OS
|
1
|
| 1 |
Ki = 0.3388 nM
|
|
|
|
CP0468311
|
5-[5-[3-[1-(3,5-dichlorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26Cl2N6OS
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0055058
|
3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol
Show/Hide
|
C23H26N2O
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0398324
|
5-[5-[3-[(2R,3R)-2-[2-fluoro-4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
|
| 1 |
Ki = 0.4169 nM
|
|
|
|
CP0445694
|
5-[5-[3-[(2S,3S)-2-(3,5-dichlorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25Cl2N5OS
|
1
|
| 1 |
Ki = 0.4169 nM
|
|
|
|
CP0300572
|
3-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C26H28F3N5OS
|
1
|
| 1 |
Ki = 0.4677 nM
|
|
|
|
CP0413983
|
(2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C16H25NO
|
1
|
| 1 |
Ki = 0.54 nM
|
|
|
|
CP0791662
|
6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C17H27NO
|
1
|
| 1 |
Ki = 0.54 nM
|
|
|
|
CP0476087
|
4-methyl-5-[4-methyl-5-[3-[(2R,3R)-2-[2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 0.5495 nM
|
|
|
|
CP0044536
|
(2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C16H25NO
|
1
|
| 1 |
Ki = 0.57 nM
|
|
|
|
CP0510743
|
(2R,3S)-5-[3-[(4-methyl-5-thiophen-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N4S2
|
1
|
| 1 |
Ki = 0.5754 nM
|
|
|
|
CP0401866
|
(2R,3S)-5-[3-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N4S2
|
1
|
| 1 |
Ki = 0.6026 nM
|
|
|
|
CP0103545
|
(-)-5-hydroxy-2-(dipropylamino)tetralin
Show/Hide
|
C16H25NO
|
1
|
| 1 |
Ki = 0.66 nM
|
|
|
|
CP0406988
|
7-Propylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 0.66 nM
|
|
|
|
CP0405626
|
7-(Ethyl-methyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 0.71 nM
|
|
|
|
CP0439589
|
7-(Methyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki = 0.74 nM
|
|
|
|
CP0437030
|
6-Propylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0442595
|
7-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C19H25NOS
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0414386
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[2-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7OS
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0380527
|
(2R,3S)-5-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0404236
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C23H31N3OS
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0386381
|
5-[5-[3-[(2R,3R)-2-(2,4-difluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25F2N5OS
|
1
|
| 1 |
Ki = 0.8128 nM
|
|
|
|
CP0419780
|
2-[4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]acetamide
Show/Hide
|
C27H30F3N5OS
|
1
|
| 1 |
Ki = 0.8511 nM
|
|
|
|
CP0380541
|
6-N,6-N-dipropyl-5,6,7,8-tetrahydroquinoline-2,6-diamine
Show/Hide
|
C15H25N3
|
1
|
| 1 |
Ki = 0.87 nM
|
|
|
|
CP0465118
|
5-[5-[3-[(2S,3R)-2-(4-fluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26FN5OS
|
1
|
| 1 |
Ki = 0.912 nM
|
|
|
|
CP0396191
|
5-[5-[3-[(2R,3S)-2-(3,5-dichlorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25Cl2N5OS
|
1
|
| 1 |
Ki = 0.9772 nM
|
|
|
|
CP0468309
|
4-methyl-5-[4-methyl-5-[3-[1-[2-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H27F3N6O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0514940
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-(2,4,6-trifluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C22H24F3N7S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0551286
|
(2R,3S)-5-[3-[(4-methyl-5-pyrimidin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N6S
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1
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| 1 |
Ki = 1.023 nM
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CP0445692
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5-[5-[3-[(2S,3S)-2-[4-fluoro-2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C23H25F4N5OS
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1
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| 1 |
Ki = 1.047 nM
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CP0507038
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(2R,3S)-5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C24H26F3N5S
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1
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| 1 |
Ki = 1.096 nM
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CP0391260
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(4aS,10bR)-4-propyl-3,4a,5,10b-tetrahydro-1H-chromeno[3,4-d][1,3]oxazin-9-ol
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C14H19NO3
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1
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| 1 |
Ki = 1.1 nM
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CP0476096
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(2S,3S)-2-[2-fluoro-4-(trifluoromethyl)phenyl]-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-5-azaspiro[2.4]heptane
Show/Hide
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C24H25F4N5S
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1
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| 1 |
Ki = 1.175 nM
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CP0518055
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5-[3-[(4-methyl-5-pyrimidin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H26F3N7S
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1
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| 1 |
Ki = 1.259 nM
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CP0419781
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(2R,3S)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N6S
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1
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| 1 |
Ki = 1.259 nM
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CP0420595
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6-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxamide
Show/Hide
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C26H29F3N6OS
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1
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| 1 |
Ki = 1.259 nM
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CP0396198
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(2S,3S)-2-(2,4-difluorophenyl)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F2N5S
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1
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| 1 |
Ki = 1.288 nM
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CP0396192
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2-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
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C22H24F3N5S2
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1
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| 1 |
Ki = 1.38 nM
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CP0419778
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(2R,3S)-5-[3-[[5-(furan-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N4OS
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1
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| 1 |
Ki = 1.38 nM
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CP0413018
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6-N,6-N-dipropyl-6,7-dihydro-5H-cyclopenta[f][1,3]benzothiazole-2,6-diamine
Show/Hide
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C16H23N3S
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1
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| 1 |
Ki = 1.4 nM
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CP0428555
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7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
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C12H17NO
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1
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| 1 |
Ki = 1.41 nM
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CP0510730
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5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Show/Hide
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C25H25F3N6S
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1
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| 1 |
Ki = 1.445 nM
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CP0401205
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(trans)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol
Show/Hide
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C14H19NO2S
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1
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| 1 |
Ki = 1.56 nM
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CP0368307
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5-[5-[3-[1-[2-fluoro-4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C23H26F4N6OS
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1
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| 1 |
Ki = 1.585 nM
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CP0404648
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5-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C24H27F3N6S
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1
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| 1 |
Ki = 1.585 nM
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CP0380480
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(2R,3S)-5-[3-[[4-methyl-5-(oxan-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C24H31F3N4OS
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1
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| 1 |
Ki = 1.66 nM
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CP0396193
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(2R,3S)-5-[3-[[5-(furan-3-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N4OS
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1
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| 1 |
Ki = 1.66 nM
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CP0473908
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1-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridin-2-one
Show/Hide
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C25H28F3N5OS
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1
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| 1 |
Ki = 1.738 nM
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CP0476095
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(2R,3S)-5-[3-[[4-methyl-5-(2-methylpyrazol-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H27F3N6S
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1
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| 1 |
Ki = 1.738 nM
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CP0448444
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6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
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C19H25NOS
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1
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| 1 |
Ki = 1.82 nM
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CP0476098
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(2R,3S)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C24H26F3N5S
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1
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| 1 |
Ki = 1.82 nM
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CP0453529
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6-N,6-N-dipropyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
Show/Hide
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C13H23N3S
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1
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| 1 |
Ki = 1.9 nM
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CP0494825
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7-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
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C21H27NO
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1
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| 1 |
Ki = 1.98 nM
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CP0066235
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4-methyl-5-[4-methyl-5-[3-(1-phenyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl)propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C22H28N6OS
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1
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| 1 |
Ki = 1.995 nM
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CP0404645
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1-(4-fluorophenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C22H26FN7S
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1
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| 1 |
Ki = 1.995 nM
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CP0404649
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2-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
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C22H25F3N6S2
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1
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| 1 |
Ki = 1.995 nM
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CP0404657
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5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C24H27F3N6S
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1
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| 1 |
Ki = 1.995 nM
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CP0414436
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3-[5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]benzonitrile
Show/Hide
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C23H26N8S
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1
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| 1 |
Ki = 1.995 nM
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CP0396199
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(2R,3S)-2-(4-fluorophenyl)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H26FN5S
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1
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| 1 |
Ki = 1.995 nM
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CP0476093
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(2R,3S)-5-[3-[[4-methyl-5-(1-methylpyrazol-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H27F3N6S
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1
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| 1 |
Ki = 2.399 nM
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CP0414725
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1-(2,6-difluorophenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C22H25F2N7S
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1
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| 1 |
Ki = 2.512 nM
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CP0420012
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3-methyl-5-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,2-oxazole
Show/Hide
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C23H27F3N6OS
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1
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| 1 |
Ki = 2.512 nM
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CP0468310
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5-[5-[3-[1-(2,6-difluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C22H26F2N6OS
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1
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| 1 |
Ki = 2.512 nM
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CP0396200
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(2R,3S)-5-[3-[[5-(2-methoxypyridin-3-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C25H28F3N5OS
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1
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| 1 |
Ki = 2.57 nM
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CP0073517
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6-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-3-ylamine
Show/Hide
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C20H21N3
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1
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| 1 |
Ki = 2.6 nM
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CP0419779
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3-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,2-oxazole
Show/Hide
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C23H26F3N5OS
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1
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| 1 |
Ki = 2.692 nM
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CP0398323
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N-[4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]cyclohexyl]acetamide
Show/Hide
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C27H36F3N5OS
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1
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| 1 |
Ki = 2.754 nM
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CP0476091
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4-[4-methyl-5-[3-[(2S,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]thiadiazole
Show/Hide
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C21H23F3N6S2
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1
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| 1 |
Ki = 2.754 nM
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CP0412072
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(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol
Show/Hide
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C14H19NO2S
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1
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| 1 |
Ki = 2.87 nM
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CP0921606
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5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]-1,3-benzothiazol-2-amine
Show/Hide
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C22H28N4O2S
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1
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| 1 |
Ki = 3.02 nM
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CP0404638
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1-(4-fluoro-3-methoxyphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H28FN7OS
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1
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| 1 |
Ki = 3.162 nM
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CP0414437
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5-[3-[[4-methyl-5-(1-methylpyrazol-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H28F3N7S
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1
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| 1 |
Ki = 3.162 nM
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CP0414719
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5-[5-[3-[1-(3-fluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C22H27FN6OS
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1
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| 1 |
Ki = 3.162 nM
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CP0468306
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5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C24H27F3N6S
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1
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| 1 |
Ki = 3.162 nM
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CP0398325
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4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]thiadiazole
Show/Hide
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C21H23F3N6S2
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1
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| 1 |
Ki = 3.162 nM
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CP0380640
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(2R,3S)-5-[3-[[4-methyl-5-(8-oxabicyclo[3.2.1]octan-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C26H33F3N4OS
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1
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| 1 |
Ki = 3.236 nM
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CP0211490
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(2R,3S)-5-[3-[[5-(2,6-dimethylpyridin-3-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C26H30F3N5S
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1
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| 1 |
Ki = 3.311 nM
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CP0420656
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(2R,3S)-5-[3-[[4-methyl-5-(2-methylpyridin-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C25H28F3N5S
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1
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| 1 |
Ki = 3.311 nM
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CP0374327
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(R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
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C21H27NO
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1
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| 1 |
Ki = 3.37 nM
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CP0405425
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(cis)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO2S
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1
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| 1 |
Ki = 3.58 nM
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CP0476094
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4-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
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C23H26F3N5S2
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1
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| 1 |
Ki = 3.631 nM
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CP0430512
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N-[4-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C23H30N4
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1
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| 1 |
Ki = 3.7 nM
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CP0077362
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N-[2-(3-chloro-4-methylphenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
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C18H22ClNO2
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1
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| 1 |
Ki = 3.9 nM
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CP0443497
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1-[2-fluoro-6-(trifluoromethyl)phenyl]-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H25F4N7S
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1
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| 1 |
Ki = 3.981 nM
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CP0443498
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1-(3-methylphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H29N7S
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1
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| 1 |
Ki = 3.981 nM
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CP0455671
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5-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1H-pyridin-2-one
Show/Hide
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C24H27F3N6OS
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1
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| 1 |
Ki = 3.981 nM
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CP0565597
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(2R,3S)-5-[3-[(4-methyl-5-pyridazin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N6S
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1
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| 1 |
Ki = 3.981 nM
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CP0343133
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(S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
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C19H25NOS
|
2
|
| 1 |
Ki = 3.99 nM
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| 2 |
Ki = 4 nM
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CP0409085
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((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
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C18H29NO
|
2
|
| 1 |
Ki = 4 nM
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| 2 |
Ki = 4.2 nM
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CP0398322
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4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-3H-pyridin-2-one
Show/Hide
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C24H26F3N5OS
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1
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| 1 |
Ki = 4.571 nM
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CP0466921
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N-[4-[2-(4-pyridin-3-ylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C21H30N6
|
1
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| 1 |
Ki = 4.7 nM
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CP0479938
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N,N-dipropyl-5,6,7,8-tetrahydroquinolin-6-amine
Show/Hide
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C15H24N2
|
1
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| 1 |
Ki = 4.97 nM
|
|
|
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CP0503336
|
(4-{2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine
Show/Hide
|
C22H29Cl2N5
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0443257
|
5-[5-[3-[1-(2,4-dichlorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26Cl2N6OS
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
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CP0447868
|
5-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[2-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C24H27F3N6S
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
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CP0448071
|
1-(3-fluorophenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C22H26FN7S
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0518051
|
5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[2-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C24H27F3N6S
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0162288
|
7-Amino-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C10H13NO
|
1
|
| 1 |
Ki = 5.12 nM
|
|
|
|
CP0507046
|
(2S,3S)-5-[3-[(4-methyl-5-pyrimidin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N6S
|
1
|
| 1 |
Ki = 5.129 nM
|
|
|
|
CP0237860
|
4-methyl-5-[4-methyl-5-[3-[(2S,3R)-2-phenyl-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H27N5OS
|
1
|
| 1 |
Ki = 5.495 nM
|
|
|
|
CP0462048
|
1-(benzenesulfonyl)-6-(4-propylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0398327
|
1-methyl-4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridin-2-one
Show/Hide
|
C25H28F3N5OS
|
1
|
| 1 |
Ki = 5.888 nM
|
|
|
|
CP0380642
|
5-[5-[3-[(2S,3R)-2-[2-fluoro-4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
|
| 1 |
Ki = 6.166 nM
|
|
|
|
CP0200768
|
N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide
Show/Hide
|
C28H30N4O
|
2
|
| 1 |
Ki = 6.31 nM
|
|
|
| 2 |
Ki = 6.457 nM
|
|
|
|
CP0420015
|
2-[5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]benzonitrile
Show/Hide
|
C23H26N8S
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0275169
|
4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine
Show/Hide
|
C20H20N2
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0398329
|
5-[5-[3-[(2S,3R)-2-[4-fluoro-2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
|
| 1 |
Ki = 6.761 nM
|
|
|
|
CP0211927
|
5-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-2-ylamine
Show/Hide
|
C20H21N3
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0507030
|
(2R,3S)-5-[3-[[4-methyl-5-[2-(trifluoromethyl)pyridin-3-yl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C25H25F6N5S
|
1
|
| 1 |
Ki = 7.079 nM
|
|
|
|
CP0462407
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]piperidine-1-carboxamide
Show/Hide
|
C25H33F3N6OS
|
1
|
| 1 |
Ki = 7.413 nM
|
|
|
|
CP0396201
|
(2S,3S)-5-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 7.762 nM
|
|
|
|
CP0404652
|
1-(3-methoxyphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H29N7OS
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0404653
|
1-(4-methylphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H29N7S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0448069
|
4-[5-[3-[1-(4-fluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-1-methylpyridin-2-one
Show/Hide
|
C24H29FN6OS
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0476097
|
(2S,3S)-5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0921607
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]-1,3-benzothiazole
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 8.511 nM
|
|
|
|
CP0399463
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]piperidin-2-one
Show/Hide
|
C24H30F3N5OS
|
1
|
| 1 |
Ki = 8.71 nM
|
|
|
|
CP0516086
|
4-[5-[3-[1-(4-fluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-1H-pyridin-2-one
Show/Hide
|
C23H27FN6OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0396194
|
2-[4-methyl-5-[3-[(2S,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
|
C22H24F3N5S2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0396197
|
(2S,3S)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N6S
|
1
|
| 1 |
Ki = 10.72 nM
|
|
|
|
CP0460840
|
(4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine
Show/Hide
|
C23H33N5O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0418912
|
7-N,7-N-dipropyl-7,8-dihydro-6H-cyclopenta[g][1,3]benzothiazole-2,7-diamine
Show/Hide
|
C16H23N3S
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0399464
|
1-methyl-4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]piperidin-2-one
Show/Hide
|
C25H32F3N5OS
|
1
|
| 1 |
Ki = 11.48 nM
|
|
|
|
CP0467609
|
2-Phenyl-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
|
C21H25NO2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0465127
|
4-methyl-5-[4-methyl-5-[3-[(2R,3R)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 12.3 nM
|
|
|
|
CP0404651
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7OS
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0404655
|
4-methyl-5-[4-methyl-5-[3-[1-[4-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H27F3N6O2S
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0404661
|
1-(2-fluorophenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C22H26FN7S
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0414385
|
5-[3-[(4-methyl-5-pyridazin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7S
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0414720
|
4-methyl-5-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C24H29F3N6OS
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0373187
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C22H31N5
|
1
|
| 1 |
Ki = 13.7 nM
|
|
|
|
CP0396195
|
2-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C26H28F3N5OS
|
1
|
| 1 |
Ki = 15.14 nM
|
|
|
|
CP0465130
|
4-methyl-5-[4-methyl-5-[3-[(2S,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
|
C23H26F3N5S2
|
1
|
| 1 |
Ki = 15.14 nM
|
|
|
|
CP0404644
|
1-(2-methoxyphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H29N7OS
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0462047
|
1-(benzenesulfonyl)-6-(4-ethylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C20H25N3O2S
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0507045
|
(2R,3S)-5-[3-[(4-methyl-5-pyridazin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N6S
|
1
|
| 1 |
Ki = 16.6 nM
|
|
|
|
CP0050117
|
N-[2-(2-chlorophenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C17H20ClNO2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0395466
|
(3-Phenoxy-propyl)-(3-phenyl-propyl)-amine
Show/Hide
|
C18H23NO
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0446525
|
1-(benzenesulfonyl)-4-(4-propylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0395221
|
[3-[(3S)-1-(2-phenylethyl)piperidin-3-yl]phenyl] trifluoromethanesulfonate
Show/Hide
|
C20H22F3NO3S
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0445693
|
1-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]-3-[(2S,3R)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propan-2-ol
Show/Hide
|
C23H26F3N5O2S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0476086
|
5-[5-[3-[(2S,3R)-2-(2,4-difluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25F2N5OS
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0507039
|
(2S,3S)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0216424
|
3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine
Show/Hide
|
C20H20N2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0510741
|
4-methyl-5-[4-methyl-5-[2-[(2R,3R)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]ethylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H24F3N5OS
|
1
|
| 1 |
Ki = 22.39 nM
|
|
|
|
CP0430456
|
N-methyl-N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C23H33N5
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0410831
|
1-(benzenesulfonyl)-5-(4-propylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0414435
|
1-[4-fluoro-2-(trifluoromethyl)phenyl]-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H25F4N7S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0877515
|
6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine
Show/Hide
|
C21H29Cl2N5S
|
1
|
| 1 |
Ki = 25.7 nM
|
|
|
|
CP0338014
|
AJ 76
Show/Hide
|
C15H23NO
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0392723
|
N-[4-[2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C21H30N6
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0446528
|
1-(benzenesulfonyl)-6-(1-propylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C22H28N2O2S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0465124
|
4-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 26.3 nM
|
|
|
|
CP0459059
|
2-(benzenesulfonyl)-4-(4-propylpiperazin-1-yl)-1,3-dihydroisoindole
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0448483
|
N,N-dipropyl-4,5,6,7-tetrahydro-1-benzothiophen-6-amine
Show/Hide
|
C14H23NS
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0902275
|
6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
|
C21H28Cl2N4S
|
1
|
| 1 |
Ki = 28.18 nM
|
|
|
|
CP0519603
|
5-[5-[3-[(2R,3R)-2-(4-fluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26FN5OS
|
1
|
| 1 |
Ki = 28.84 nM
|
|
|
|
CP0395430
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C22H31N5
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0494751
|
9-Oxo-1-propyl-2,3,4a,9,10,10a-hexahydro-1H-4-oxa-9lambda*4*-thia-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO3S
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0396203
|
(2R,3S)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-phenyl-5-azaspiro[2.4]heptane
Show/Hide
|
C23H27N5S
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1
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| 1 |
Ki = 29.51 nM
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CP0059618
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N-[2-(4-chlorophenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
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C17H20ClNO2
|
1
|
| 1 |
Ki = 31 nM
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CP0404659
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1-(4-methoxyphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H29N7OS
|
1
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| 1 |
Ki = 31.62 nM
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CP0468307
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6-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-4-[4-(trifluoromethyl)phenyl]-2,3,4a,5,7,7a-hexahydropyrrolo[3,4-b][1,4]oxazine
Show/Hide
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C23H27F3N6O2S
|
1
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| 1 |
Ki = 31.62 nM
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CP0503028
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N-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
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C23H30F3N5
|
1
|
| 1 |
Ki = 32 nM
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CP0505971
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(4-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine
Show/Hide
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C23H33N5O
|
1
|
| 1 |
Ki = 32 nM
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CP0396202
|
(2S,3S)-5-[3-[(4-methyl-5-pyridazin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N6S
|
1
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| 1 |
Ki = 35.48 nM
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CP0482852
|
3-[(S)-1-(3-Phenyl-propyl)-piperidin-3-yl]-benzonitrile
Show/Hide
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C21H24N2
|
1
|
| 1 |
Ki = 36 nM
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CP0413089
|
N,N-dipropyl-4,5,6,7-tetrahydro-1H-indazol-5-amine
Show/Hide
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C13H23N3
|
1
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| 1 |
Ki = 36 nM
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CP0468740
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6-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxylic acid
Show/Hide
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C26H28F3N5O2S
|
1
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| 1 |
Ki = 36.31 nM
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CP0420260
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4-methyl-5-[4-methyl-5-[3-[6-[4-(trifluoromethyl)phenyl]-3,6-diazabicyclo[3.2.0]heptan-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C22H25F3N6OS
|
1
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| 1 |
Ki = 39.81 nM
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CP0430235
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N-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
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C21H28N4
|
1
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| 1 |
Ki = 40 nM
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CP0404640
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N,N-dipropyl-4,5,6,7-tetrahydro-1-benzothiophen-5-amine
Show/Hide
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C14H23NS
|
1
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| 1 |
Ki = 40 nM
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CP0420797
|
[(5S,6R)-6-(dipropylamino)-5-methyl-5,6,7,8-tetrahydronaphthalen-1-yl] trifluoromethanesulfonate
Show/Hide
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C18H26F3NO3S
|
1
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| 1 |
Ki = 40 nM
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CP0465123
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4-methyl-5-[4-methyl-5-[3-[(2R,3R)-2-phenyl-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C22H27N5OS
|
1
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| 1 |
Ki = 41.69 nM
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CP0380641
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4-methyl-5-[4-methyl-5-[4-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]butylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C24H28F3N5OS
|
1
|
| 1 |
Ki = 45.71 nM
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CP0404510
|
(4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine
Show/Hide
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C22H30FN5
|
1
|
| 1 |
Ki = 48 nM
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CP0462058
|
1-(benzenesulfonyl)-5-(4-ethylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
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C20H25N3O2S
|
1
|
| 1 |
Ki = 48 nM
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CP0269448
|
N-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]-4-methylbenzamide
Show/Hide
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C19H22ClN3O
|
1
|
| 1 |
Ki = 49 nM
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CP0404650
|
5-[3-[(4-methyl-5-pyrimidin-5-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H26F3N7S
|
1
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| 1 |
Ki = 50.12 nM
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CP0447885
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5-[3-[(4-methyl-5-pyridazin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H26F3N7S
|
1
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| 1 |
Ki = 50.12 nM
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CP0039002
|
1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one(Azaperone)
Show/Hide
|
C19H22FN3O
|
1
|
| 1 |
Ki = 53 nM
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CP0398029
|
N-[4-[3-(4-phenylpiperazin-1-yl)propyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
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C23H33N5
|
1
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| 1 |
Ki = 54 nM
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CP0454453
|
3-[(S)-1-(2-Ethyl-thiophen-3-yl)-piperidin-3-yl]-benzonitrile
Show/Hide
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C18H20N2S
|
1
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| 1 |
Ki = 56 nM
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CP0454875
|
(3-Phenylsulfanyl-propyl)-(2-p-tolyloxy-ethyl)-amine
Show/Hide
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C18H23NOS
|
1
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| 1 |
Ki = 56 nM
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CP0448509
|
(7S)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
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C16H25NO
|
1
|
| 1 |
Ki = 58 nM
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CP0440416
|
3-((S)-1-Phenethyl-piperidin-3-yl)-benzonitrile
Show/Hide
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C20H22N2
|
1
|
| 1 |
Ki = 59 nM
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CP0393312
|
3-Benzyl-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H19NO3
|
1
|
| 1 |
Ki = 60 nM
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CP0431124
|
N-propyl-N-(4,5,6,7-tetrahydro-1-benzothiophen-6-ylmethyl)propan-1-amine
Show/Hide
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C15H25NS
|
1
|
| 1 |
Ki = 60 nM
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CP0398241
|
(3-propyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-6-yl) trifluoromethanesulfonate
Show/Hide
|
C16H20F3NO3S
|
1
|
| 1 |
Ki = 61 nM
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CP0269449
|
4-Chloro-N-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
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C18H19Cl2N3O
|
1
|
| 1 |
Ki = 66 nM
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CP0146487
|
(2-Phenoxy-ethyl)-(3-p-tolyloxy-propyl)-amine
Show/Hide
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C18H23NO2
|
1
|
| 1 |
Ki = 66 nM
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CP0478351
|
(3-prop-2-enyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-6-yl) trifluoromethanesulfonate
Show/Hide
|
C16H18F3NO3S
|
1
|
| 1 |
Ki = 67 nM
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CP0448607
|
(-)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester
Show/Hide
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C15H20F3NO3S
|
1
|
| 1 |
Ki = 68 nM
|
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CP0482470
|
1-(benzenesulfonyl)-6-(4-methylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C19H23N3O2S
|
1
|
| 1 |
Ki = 68 nM
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CP0462080
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1-(benzenesulfonyl)-4-(4-ethylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
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C20H25N3O2S
|
1
|
| 1 |
Ki = 72 nM
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CP0059512
|
N-[2-(3,4-dimethylphenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
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C19H25NO2
|
1
|
| 1 |
Ki = 73 nM
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CP0469321
|
2-(benzenesulfonyl)-4-(4-ethylpiperazin-1-yl)-1,3-dihydroisoindole
Show/Hide
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C20H25N3O2S
|
1
|
| 1 |
Ki = 73 nM
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CP0465122
|
5-[5-[3-[(2R,3R)-2-[4-fluoro-2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
|
| 1 |
Ki = 75.86 nM
|
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CP0401215
|
(R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C16H25NO
|
1
|
| 1 |
Ki = 76 nM
|
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CP0403814
|
(S)-1-Propyl-3-(3-thiophen-3-yl-phenyl)-piperidine
Show/Hide
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C18H23NS
|
1
|
| 1 |
Ki = 78 nM
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CP0449207
|
3-((S)-1-Propyl-piperidin-3-yl)-benzaldehyde
Show/Hide
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C15H21NO
|
1
|
| 1 |
Ki = 83 nM
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CP0504193
|
4-(2-Thiophen-2-yl-ethyl)-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
|
C18H21NO2S
|
1
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| 1 |
Ki = 83 nM
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CP0448598
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(S)-1-Propyl-3-(3-propyl-phenyl)-piperidine
Show/Hide
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C17H27N
|
1
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| 1 |
Ki = 86 nM
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CP0486407
|
N-[4-[(4-phenylpiperazin-1-yl)methyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
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C21H29N5
|
1
|
| 1 |
Ki = 89 nM
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CP0465125
|
5-[5-[3-[(2R,3S)-2-[4-fluoro-2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
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| 1 |
Ki = 89.13 nM
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CP0403905
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[3-[(3S)-1-propylpiperidin-3-yl]phenyl] 4-methylbenzenesulfonate
Show/Hide
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C21H27NO3S
|
1
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| 1 |
Ki = 92 nM
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CP0454510
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N-[2-(4-chlorophenoxy)ethyl]-3-phenylsulfanylpropan-1-amine
Show/Hide
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C17H20ClNOS
|
1
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| 1 |
Ki = 95 nM
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CP0473942
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1-(benzenesulfonyl)-6-(1-ethylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
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C21H26N2O2S
|
1
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| 1 |
Ki = 95 nM
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CP0476090
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4-methyl-5-[4-methyl-5-[2-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]ethylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H24F3N5OS
|
1
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| 1 |
Ki = 95.5 nM
|
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CP0507044
|
(2S,3S)-5-[3-[(4-methyl-5-pyridazin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N6S
|
1
|
| 1 |
Ki = 97.72 nM
|
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CP0159469
|
N-[2-(4-chlorophenoxy)ethyl]-3-(4-fluorophenoxy)propan-1-amine
Show/Hide
|
C17H19ClFNO2
|
1
|
| 1 |
Ki = 98 nM
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CP0446521
|
2-(benzenesulfonyl)-5-(4-propylpiperazin-1-yl)-1,3-dihydroisoindole
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 103 nM
|
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CP0373104
|
3-((S)-1-sec-Butyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C16H22N2
|
1
|
| 1 |
Ki = 105 nM
|
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CP0526746
|
N,N-bis(2-thiophen-3-ylethyl)propan-1-amine
Show/Hide
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C15H21NS2
|
1
|
| 1 |
Ki = 108 nM
|
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CP0459047
|
1-(benzenesulfonyl)-5-(4-methylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C19H23N3O2S
|
1
|
| 1 |
Ki = 108 nM
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CP0404069
|
((R)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-(2-thiophen-2-yl-ethyl)-amine
Show/Hide
|
C20H27NOS
|
1
|
| 1 |
Ki = 113 nM
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CP0460133
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N-(2-thiophen-2-ylethyl)-N-(2-thiophen-3-ylethyl)propan-1-amine
Show/Hide
|
C15H21NS2
|
1
|
| 1 |
Ki = 117 nM
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CP0410834
|
1-(benzenesulfonyl)-6-(1-methylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C20H24N2O2S
|
1
|
| 1 |
Ki = 121 nM
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CP0526678
|
(S)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-ol
Show/Hide
|
C19H24FN3O
|
1
|
| 1 |
Ki = 125 nM
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CP0404660
|
1-(2-methylphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H29N7S
|
1
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| 1 |
Ki = 125.89 nM
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CP0468308
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4-[5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]benzonitrile
Show/Hide
|
C23H26N8S
|
1
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| 1 |
Ki = 125.89 nM
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CP0465128
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4-methyl-5-[4-methyl-5-[3-[(2S,3R)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 128.82 nM
|
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CP0082770
|
(-)-3-(1-Propyl-piperidin-3-yl)-phenol
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki = 132 nM
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CP0410829
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1-(benzenesulfonyl)-5-piperazin-1-yl-2,3-dihydroindole
Show/Hide
|
C18H21N3O2S
|
1
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| 1 |
Ki = 133 nM
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CP0375804
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(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki = 136 nM
|
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CP0059535
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(2-Phenoxy-ethyl)-(3-phenoxy-propyl)-amine
Show/Hide
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C17H21NO2
|
1
|
| 1 |
Ki = 136 nM
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CP0454451
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(S)-3-(3-Methylsulfanyl-phenyl)-1-propyl-piperidine
Show/Hide
|
C15H23NS
|
1
|
| 1 |
Ki = 139 nM
|
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CP0405312
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((S)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-(2-thiophen-2-yl-ethyl)-amine
Show/Hide
|
C20H27NOS
|
1
|
| 1 |
Ki = 154 nM
|
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CP0402371
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(2-Methoxy-5,6,7,8-tetrahydro-quinolin-6-yl)-dipropyl-amine
Show/Hide
|
C16H26N2O
|
1
|
| 1 |
Ki = 158 nM
|
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CP0390672
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2-(benzenesulfonyl)-4-(4-methylpiperazin-1-yl)-1,3-dihydroisoindole
Show/Hide
|
C19H23N3O2S
|
1
|
| 1 |
Ki = 160 nM
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CP0902273
|
6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
|
C21H30N4OS
|
1
|
| 1 |
Ki = 165.96 nM
|
|
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CP0178983
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(3-Phenoxy-propyl)-(2-p-tolyloxy-ethyl)-amine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
Ki = 169 nM
|
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|
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CP0420370
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N,N-dimethyl-3-[(3S)-1-propylpiperidin-3-yl]benzenesulfonamide
Show/Hide
|
C16H26N2O2S
|
1
|
| 1 |
Ki = 170 nM
|
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CP0439610
|
(S)-3-(3-Bromo-phenyl)-1-propyl-piperidine
Show/Hide
|
C14H20BrN
|
1
|
| 1 |
Ki = 171 nM
|
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|
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CP0494145
|
[(5S,6R)-5-methyl-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-yl] trifluoromethanesulfonate
Show/Hide
|
C15H20F3NO3S
|
1
|
| 1 |
Ki = 171 nM
|
|
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CP0459054
|
1-(benzenesulfonyl)-6-(4-cyclobutylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 173 nM
|
|
|
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CP0467676
|
1-(benzenesulfonyl)-4-(4-methylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C19H23N3O2S
|
1
|
| 1 |
Ki = 173 nM
|
|
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CP0215268
|
N-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-4-methylbenzamide
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 174 nM
|
|
|
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CP0110876
|
N-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]benzamide
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
Ki = 177 nM
|
|
|
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CP0159467
|
N-[2-(4-chlorophenoxy)ethyl]-3-(4-methylphenoxy)propan-1-amine
Show/Hide
|
C18H22ClNO2
|
1
|
| 1 |
Ki = 177 nM
|
|
|
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CP0141761
|
(2-p-Tolyloxy-ethyl)-(3-m-tolyloxy-propyl)-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 192 nM
|
|
|
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CP0410833
|
1-(benzenesulfonyl)-5-(4-cyclobutylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 208 nM
|
|
|
|
CP0461007
|
N-[4-[2-(4-pyrazin-2-ylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C20H29N7
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0409110
|
(5-Cyclopentyloxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-(2-thiophen-2-yl-ethyl)-amine
Show/Hide
|
C24H33NOS
|
1
|
| 1 |
Ki = 211 nM
|
|
|
|
CP0459057
|
2-(benzenesulfonyl)-4-(1-propylpiperidin-4-yl)-1,3-dihydroisoindole
Show/Hide
|
C22H28N2O2S
|
1
|
| 1 |
Ki = 212 nM
|
|
|
|
CP0409290
|
(R)-1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol
Show/Hide
|
C20H25NO3
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
1
|
| 1 |
Ki = 222 nM
|
|
|
|
CP0410827
|
1-(benzenesulfonyl)-5-(1-propylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C22H28N2O2S
|
1
|
| 1 |
Ki = 227 nM
|
|
|
|
CP0059517
|
3-(4-fluorophenoxy)-N-[2-(4-methylphenoxy)ethyl]propan-1-amine
Show/Hide
|
C18H22FNO2
|
1
|
| 1 |
Ki = 232 nM
|
|
|
|
CP0146505
|
(2-p-Tolyloxy-ethyl)-(3-p-tolyloxy-propyl)-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 235 nM
|
|
|
|
CP0077361
|
4-[2-(3-Phenoxy-propylamino)-ethoxy]-phenol
Show/Hide
|
C17H21NO3
|
1
|
| 1 |
Ki = 236 nM
|
|
|
|
CP0964096
|
6-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
|
C20H28N4OS
|
1
|
| 1 |
Ki = 239.88 nM
|
|
|
|
CP0441462
|
6-Propyl-4,5a,6,7,8,9a-hexahydro-5H-9-oxa-3-thia-6-aza-cyclopenta[a]naphthalene
Show/Hide
|
C13H19NOS
|
1
|
| 1 |
Ki = 240 nM
|
|
|
|
CP0405530
|
N-propyl-N-(4,5,6,7-tetrahydro-1-benzothiophen-5-ylmethyl)propan-1-amine
Show/Hide
|
C15H25NS
|
1
|
| 1 |
Ki = 247 nM
|
|
|
|
CP0449181
|
3-((S)-1-Propyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C15H20N2
|
1
|
| 1 |
Ki = 249 nM
|
|
|
|
CP0424568
|
(5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid methyl ester
Show/Hide
|
C16H23NO2
|
1
|
| 1 |
Ki = 253 nM
|
|
|
|
CP0902274
|
5-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3a,4,6,7,8,8a-hexahydrothiazolo[5,4-c]azepine
Show/Hide
|
C21H30N4OS
|
1
|
| 1 |
Ki = 257.04 nM
|
|
|
|
CP0447814
|
((S)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
|
C17H27NO
|
1
|
| 1 |
Ki = 266 nM
|
|
|
|
CP0448764
|
3-((S)-1-Isopropyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C15H20N2
|
1
|
| 1 |
Ki = 268 nM
|
|
|
|
CP0110881
|
4-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 268 nM
|
|
|
|
CP0899498
|
6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
|
C22H32N4OS
|
1
|
| 1 |
Ki = 309.03 nM
|
|
|
|
CP0429011
|
3-(4-Chloro-benzyl)-8-hydroxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C19H16ClNO3
|
1
|
| 1 |
Ki = 317 nM
|
|
|
|
CP0462051
|
1-(benzenesulfonyl)-5-(1-ethylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C21H26N2O2S
|
1
|
| 1 |
Ki = 321 nM
|
|
|
|
CP0502546
|
(S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol
Show/Hide
|
C21H25ClFNO2
|
1
|
| 1 |
Ki = 330 nM
|
|
|
|
CP0410821
|
1-(benzenesulfonyl)-6-piperazin-1-yl-2,3-dihydroindole
Show/Hide
|
C18H21N3O2S
|
1
|
| 1 |
Ki = 330 nM
|
|
|
|
CP0460417
|
[4-[(3S)-1-propylpiperidin-3-yl]-2-(trifluoromethylsulfonyloxy)phenyl] trifluoromethanesulfonate
Show/Hide
|
C16H19F6NO6S2
|
1
|
| 1 |
Ki = 338 nM
|
|
|
|
CP0405628
|
3-Benzyl-8-methyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H19NO2
|
1
|
| 1 |
Ki = 338 nM
|
|
|
|
CP0403548
|
(S)-3-(3-Ethynyl-phenyl)-1-propyl-piperidine
Show/Hide
|
C16H21N
|
1
|
| 1 |
Ki = 339 nM
|
|
|
|
CP0348498
|
6-Amino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C10H13NO
|
1
|
| 1 |
Ki = 343 nM
|
|
|
|
CP0269451
|
N-[2-(4-nitrophenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C17H20N2O4
|
1
|
| 1 |
Ki = 345 nM
|
|
|
|
CP0374180
|
(3-Phenoxy-propyl)-(3-p-tolyl-propyl)-amine
Show/Hide
|
C19H25NO
|
1
|
| 1 |
Ki = 347 nM
|
|
|
|
CP0456715
|
(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-amine
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 361 nM
|
|
|
|
CP0446529
|
1-(benzenesulfonyl)-6-(1-cyclobutylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C23H28N2O2S
|
1
|
| 1 |
Ki = 362 nM
|
|
|
|
CP0374678
|
3-Chloro-N-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C18H19Cl2N3O
|
1
|
| 1 |
Ki = 364 nM
|
|
|
|
CP0409707
|
(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
|
C17H27NO
|
1
|
| 1 |
Ki = 366 nM
|
|
|
|
CP0098943
|
N-[2-(4-methoxyphenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C18H23NO3
|
1
|
| 1 |
Ki = 369 nM
|
|
|
|
CP0505664
|
(R)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-ol
Show/Hide
|
C19H24FN3O
|
1
|
| 1 |
Ki = 374 nM
|
|
|
|
CP0178951
|
N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-4-methylbenzamide
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
Ki = 377 nM
|
|
|
|
CP0059513
|
(2-p-Tolyloxy-ethyl)-(3-o-tolyloxy-propyl)-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 381 nM
|
|
|
|
CP0462050
|
1-(benzenesulfonyl)-4-(1-propylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C22H28N2O2S
|
1
|
| 1 |
Ki = 383 nM
|
|
|
|
CP0415471
|
1-(benzenesulfonyl)-5-(1-methylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C20H24N2O2S
|
1
|
| 1 |
Ki = 401 nM
|
|
|
|
CP0442593
|
(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-methyl-amine
Show/Hide
|
C12H17NO
|
1
|
| 1 |
Ki = 409 nM
|
|
|
|
CP0040248
|
7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-one
Show/Hide
|
C18H18N2O2
|
1
|
| 1 |
Ki = 424 nM
|
|
|
|
CP0921608
|
N-[4-(4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-6-yl)butyl]adamantane-1-carboxamide
Show/Hide
|
C22H33N3OS
|
1
|
| 1 |
Ki = 446.68 nM
|
|
|
|
CP0410826
|
1-(benzenesulfonyl)-4-(4-cyclobutylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 449 nM
|
|
|
|
CP0420854
|
(S)-1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol
Show/Hide
|
C20H25NO3
|
1
|
| 1 |
Ki = 457 nM
|
|
|
|
CP0178940
|
N-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]-3-methylbenzamide
Show/Hide
|
C19H22ClN3O
|
1
|
| 1 |
Ki = 464 nM
|
|
|
|
CP0422922
|
8-Methoxy-3-(4-methyl-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C21H21NO3
|
1
|
| 1 |
Ki = 491 nM
|
|
|
|
CP0483810
|
N-ethyl-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 501 nM
|
|
|
|
CP0410822
|
2-(benzenesulfonyl)-4-piperazin-1-yl-1,3-dihydroisoindole
Show/Hide
|
C18H21N3O2S
|
1
|
| 1 |
Ki = 505 nM
|
|
|
|
CP0397448
|
2-[3-[(3S)-1-propylpiperidin-3-yl]phenyl]acetonitrile
Show/Hide
|
C16H22N2
|
1
|
| 1 |
Ki = 509 nM
|
|
|
|
CP0380569
|
8-N,8-N-dipropyl-8,9-dihydro-7H-pyrano[2,3-g][1,3]benzothiazole-2,8-diamine
Show/Hide
|
C16H23N3OS
|
1
|
| 1 |
Ki = 510 nM
|
|
|
|
CP0404021
|
3-((S)-1-Ethyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C14H18N2
|
1
|
| 1 |
Ki = 514 nM
|
|
|
|
CP0528497
|
1-(benzenesulfonyl)-6-piperidin-4-yl-2,3-dihydroindole
Show/Hide
|
C19H22N2O2S
|
1
|
| 1 |
Ki = 517 nM
|
|
|
|
CP0454452
|
3-((S)-1-Cyclopropylmethyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C16H20N2
|
1
|
| 1 |
Ki = 522 nM
|
|
|
|
CP0482523
|
2-(benzenesulfonyl)-4-(4-cyclobutylpiperazin-1-yl)-1,3-dihydroisoindole
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 525 nM
|
|
|
|
CP0221754
|
(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
|
C17H27NO
|
1
|
| 1 |
Ki = 529 nM
|
|
|
|
CP0375013
|
1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol
Show/Hide
|
C20H25NO3
|
1
|
| 1 |
Ki = 537 nM
|
|
|
|
CP0448817
|
3-(4-Fluoro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H18FNO3
|
1
|
| 1 |
Ki = 548 nM
|
|
|
|
CP0482522
|
2-(benzenesulfonyl)-4-(1-ethylpiperidin-4-yl)-1,3-dihydroisoindole
Show/Hide
|
C21H26N2O2S
|
1
|
| 1 |
Ki = 562 nM
|
|
|
|
CP0383244
|
(S)-1-Propyl-3-m-tolyl-piperidine
Show/Hide
|
C15H23N
|
1
|
| 1 |
Ki = 573 nM
|
|
|
|
CP0505972
|
CHEMBL349980
Show/Hide
|
C20H29N7
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0432916
|
8-Methoxy-3-phenethyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C21H21NO3
|
1
|
| 1 |
Ki = 591 nM
|
|
|
|
CP0462049
|
1-(benzenesulfonyl)-4-(1-ethylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C21H26N2O2S
|
1
|
| 1 |
Ki = 591 nM
|
|
|
|
CP0269450
|
4-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H19ClN4O
|
1
|
| 1 |
Ki = 600 nM
|
|
|
|
CP0405129
|
Butyl-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine
Show/Hide
|
C15H23NO
|
1
|
| 1 |
Ki = 603 nM
|
|
|
|
CP0409239
|
1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole
Show/Hide
|
C19H17ClN2O2S
|
1
|
| 1 |
Ki = 627 nM
|
|
|
|
CP0443640
|
(S)-3-Piperidin-3-yl-benzonitrile
Show/Hide
|
C12H14N2
|
1
|
| 1 |
Ki = 631 nM
|
|
|
|
CP0419743
|
((R)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
|
C17H27NO
|
1
|
| 1 |
Ki = 648 nM
|
|
|
|
CP0451585
|
3-((S)-1-Allyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C15H18N2
|
1
|
| 1 |
Ki = 658 nM
|
|
|
|
CP0275794
|
5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine
Show/Hide
|
C11H15NO
|
1
|
| 1 |
Ki = 683 nM
|
|
|
|
CP0446519
|
2-(benzenesulfonyl)-5-(4-ethylpiperazin-1-yl)-1,3-dihydroisoindole
Show/Hide
|
C20H25N3O2S
|
1
|
| 1 |
Ki = 688 nM
|
|
|
|
CP0482524
|
2-(benzenesulfonyl)-5-(1-propylpiperidin-4-yl)-1,3-dihydroisoindole
Show/Hide
|
C22H28N2O2S
|
1
|
| 1 |
Ki = 712 nM
|
|
|
|
CP0376224
|
1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole
Show/Hide
|
C19H17FN2O2S
|
1
|
| 1 |
Ki = 741 nM
|
|
|
|
CP0395196
|
(S)-3-Phenyl-1-propyl-piperidine
Show/Hide
|
C14H21N
|
1
|
| 1 |
Ki = 777 nM
|
|
|
|
CP0418838
|
N-[4-[2-(dipropylamino)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C18H32N4
|
1
|
| 1 |
Ki = 800 nM
|
|
|
|
CP0447817
|
N,N-diethyl-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C15H23NO
|
1
|
| 1 |
Ki = 857 nM
|
|
|
|
CP0860616
|
3-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide
Show/Hide
|
C20H22ClN3O2S
|
1
|
| 1 |
Ki = 930 nM
|
|
|
|
CP0375155
|
8-Methoxy-3-(4-trifluoromethyl-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C21H18F3NO3
|
1
|
| 1 |
Ki = 966 nM
|
|
|
|
CP0377270
|
[3-[(3S)-1-propylpiperidin-3-yl]phenyl] methanesulfonate
Show/Hide
|
C15H23NO3S
|
1
|
| 1 |
Ki = 978 nM
|
|
|
|
CP0535152
|
[4-[(3S)-1-propylpiperidin-3-yl]phenyl] trifluoromethanesulfonate
Show/Hide
|
C15H20F3NO3S
|
1
|
| 1 |
Ki = 1136 nM
|
|
|
|
CP0503037
|
(R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol
Show/Hide
|
C21H25ClFNO2
|
1
|
| 1 |
Ki = 1296 nM
|
|
|
|
CP0415028
|
3-Benzyl-7,8-dimethoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C21H21NO4
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0308847
|
(S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidine
Show/Hide
|
C15H23NO2S
|
1
|
| 1 |
Ki = 1305 nM
|
|
|
|
CP0401217
|
((R)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki = 1372 nM
|
|
|
|
CP0467385
|
7-N,7-N-dipropyl-7,8-dihydro-6H-pyrano[2,3-e][1,3]benzothiazole-2,7-diamine
Show/Hide
|
C16H23N3OS
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0459368
|
(S)-1-Propyl-3-[3-(2,2,2-trifluoro-ethoxy)-phenyl]-piperidine
Show/Hide
|
C16H22F3NO
|
1
|
| 1 |
Ki = 1414 nM
|
|
|
|
CP0178952
|
3-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 1450 nM
|
|
|
|
CP0403569
|
[3-[(3S)-1-propylpiperidin-3-yl]phenyl]methanol
Show/Hide
|
C15H23NO
|
1
|
| 1 |
Ki = 1461 nM
|
|
|
|
CP0416596
|
4-Phenethyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
|
C20H23NO2
|
1
|
| 1 |
Ki = 1566 nM
|
|
|
|
CP0462035
|
1-(benzenesulfonyl)-5-(1-cyclobutylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C23H28N2O2S
|
1
|
| 1 |
Ki = 1672 nM
|
|
|
|
CP0077364
|
3-(4-bromophenoxy)-N-[2-(4-methylphenoxy)ethyl]propan-1-amine
Show/Hide
|
C18H22BrNO2
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0451515
|
3-((S)-1-Methyl-piperidin-3-yl)-benzonitrile
Show/Hide
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C13H16N2
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1
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| 1 |
Ki = 1759 nM
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CP0377339
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1-[3-((S)-1-Propyl-piperidin-3-yl)-phenyl]-ethanone
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C16H23NO
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1
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| 1 |
Ki = 2150 nM
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CP0439261
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3-(4-Fluoro-benzyl)-8-methyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
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C20H18FNO2
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1
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| 1 |
Ki = 2210 nM
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CP0297070
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7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine
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C11H15NO
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1
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| 1 |
Ki = 2220 nM
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CP0040962
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3-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide
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C19H19ClN4O
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1
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| 1 |
Ki = 2270 nM
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CP0374756
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N-[4-[2-(4-pyridin-4-ylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
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C21H30N6
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1
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| 1 |
Ki = 2300 nM
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CP0311650
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N-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]benzamide
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C19H23N3O2
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1
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| 1 |
Ki = 2470 nM
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CP0076889
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N-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-3-methylbenzamide
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C20H25N3O2
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1
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| 1 |
Ki = 2480 nM
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CP0405629
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3-(2-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
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C20H18ClNO3
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1
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| 1 |
Ki = 2620 nM
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CP0449041
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3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
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C20H18ClNO3
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1
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| 1 |
Ki = 2630 nM
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CP0409709
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3-(4-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
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C20H18ClNO3
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1
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| 1 |
Ki = 2780 nM
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CP0159532
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N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide
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C20H22N4O
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1
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| 1 |
Ki = 2810 nM
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CP0465298
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4,5a,6,7,8,9a-Hexahydro-5H-9-oxa-3-thia-6-aza-cyclopenta[a]naphthalene
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C10H13NOS
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1
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| 1 |
Ki = 3000 nM
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CP0508599
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(+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol
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C14H19NO2S
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1
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| 1 |
Ki = 3003 nM
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CP0405625
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((S)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine
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C14H21NO
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1
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| 1 |
Ki = 3055 nM
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CP0899499
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6-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
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C19H28N6S
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1
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| 1 |
Ki = 3090.3 nM
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CP0398227
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[2-[(3S)-1-propylpiperidin-3-yl]phenyl] trifluoromethanesulfonate
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C15H20F3NO3S
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1
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| 1 |
Ki = 3113 nM
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CP0958935
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6-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine
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C19H29N7S
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1
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| 1 |
Ki = 3801.89 nM
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CP0962520
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6-[4-(4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-6-yl)butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
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C18H26N4S2
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1
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| 1 |
Ki = 3801.89 nM
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CP0405332
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(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol
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C14H19NO3
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1
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| 1 |
Ki > 10000 nM
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CP0453517
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(cis)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol
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C14H19NO3
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1
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| 1 |
Ki > 10000 nM
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CP0431710
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6-N-propyl-6,7-dihydro-5H-cyclopenta[f][1,3]benzothiazole-2,6-diamine
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C13H17N3S
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1
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| 1 |
Ki > 10000 nM
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CP0877516
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phenyl-[4-[2-(4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-6-yl)ethyl]piperazin-1-yl]methanone
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C20H26N4OS
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1
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| 1 |
Ki = 12302.69 nM
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CP0448943
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3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-6-carbonitrile
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C16H18N2
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1
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| 1 |
Ki > 455 nM
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CP0873359
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2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide
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C20H22ClN3O2S
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1
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| 1 |
Ki > 1000 nM
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CP0422896
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3-((S)-1-Propyl-piperidin-3-yl)-benzamide
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C15H22N2O
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1
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| 1 |
Ki > 1285 nM
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CP0440419
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3-((S)-1-Propyl-piperidin-3-yl)-benzoic acid methyl ester
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C16H23NO2
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1
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| 1 |
Ki > 1285 nM
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CP0451272
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3-((S)-1-Prop-2-ynyl-piperidin-3-yl)-benzonitrile
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C15H16N2
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1
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| 1 |
Ki > 1362 nM
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CP0433176
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3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-6-carboxylic acid amide
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C16H20N2O
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1
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| 1 |
Ki > 1500 nM
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CP0470701
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(+)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester
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C15H20F3NO3S
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1
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| 1 |
Ki > 1623 nM
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CP0266526
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(R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol
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C18H22F2N4O
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1
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| 1 |
Ki > 2000 nM
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CP0310814
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(S)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol
Show/Hide
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C18H22F2N4O
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1
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| 1 |
Ki > 2000 nM
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CP0460496
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C,C,C-Trifluoro-N-[3-((S)-1-propyl-piperidin-3-yl)-phenyl]-methanesulfonamide
Show/Hide
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C15H21F3N2O2S
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1
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| 1 |
Ki > 2000 nM
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CP0141757
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N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]benzamide
Show/Hide
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C19H20N4O
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1
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| 1 |
Ki > 3000 nM
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CP0406449
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3-(4-Chloro-benzyl)-8,9-dimethoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
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C21H20ClNO4
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1
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| 1 |
Ki > 3000 nM
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CP0424524
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8-Methoxy-3-(4-nitro-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
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C20H18N2O5
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1
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| 1 |
Ki > 3000 nM
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CP0777252
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2-Iodo-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide
Show/Hide
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C20H22IN3O2S
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1
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| 1 |
Ki > 5000 nM
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CP0853639
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2-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide
Show/Hide
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C19H20ClN3O2S
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1
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| 1 |
Ki > 5000 nM
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