Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
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 PubChem ID
CID: 5355
SID: 14802423
Canonical SMILES
CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O
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Compound Formula C15H23N3O4S
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 8 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 560 nM
   TI
   LI
   LO
   TS
2
Kd = 39.81 nM
   TI
   LI
   LO
   TS
CL000153 CHOP
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 66.22 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 120 nM