| Compound ID |
Compound Name |
Compound Formula |
|
CP0371787
|
5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine; oxalic acid
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|
C14H23N3OS
|
3
|
| 1 |
EC50 = 16.22 nM
|
|
|
| 2 |
EC50 = 186.21 nM
|
|
|
| 3 |
EC50 = 6309.57 nM
|
|
|
|
CP0378654
|
1-[3-[4-[7-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]heptyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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|
C32H47N5O2S
|
5
|
| 1 |
EC50 = 18.62 nM
|
|
|
| 2 |
EC50 = 35.48 nM
|
|
|
| 3 |
IC50 = 144.54 nM
|
|
|
| 4 |
IC50 = 407.38 nM
|
|
|
| 5 |
IC50 = 1862.09 nM
|
|
|
|
CP0378653
|
1-[3-[4-[5-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]pentyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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|
C30H43N5O2S
|
5
|
| 1 |
EC50 = 30.9 nM
|
|
|
| 2 |
EC50 = 7079.46 nM
|
|
|
| 3 |
IC50 = 354.81 nM
|
|
|
| 4 |
IC50 = 446.68 nM
|
|
|
| 5 |
IC50 = 630.96 nM
|
|
|
|
CP0635477
|
(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride
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|
C6H15ClN2O2
|
2
|
| 1 |
EC50 = 44.67 nM
|
|
|
| 2 |
EC50 = 2238.72 nM
|
|
|
|
CP0116478
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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|
C24H30N2O
|
3
|
| 1 |
EC50 = 147.91 nM
|
|
|
| 2 |
IC50 = 1230.27 nM
|
|
|
| 3 |
IC50 = 8511.38 nM
|
|
|
|
CP0016175
|
(2-Carbamoyloxy-ethyl)-trimethyl-ammonium
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|
C6H15N2O2+
|
3
|
| 1 |
EC50 = 154.88 nM
|
|
|
| 2 |
EC50 = 2290.87 nM
|
|
|
| 3 |
EC50 = 6606.93 nM
|
|
|
|
CP0232092
|
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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|
C21H32N2O
|
5
|
| 1 |
EC50 = 275.42 nM
|
|
|
| 2 |
IC50 = 177.83 nM
|
|
|
| 3 |
IC50 = 2238.72 nM
|
|
|
| 4 |
IC50 = 7585.78 nM
|
|
|
| 5 |
IC50 = 47863.01 nM
|
|
|
|
CP0232093
|
1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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|
C22H27N3O
|
2
|
| 1 |
EC50 = 588.84 nM
|
|
|
| 2 |
IC50 = 12022.64 nM
|
|
|
|
CP0378647
|
1-[3-[4-(5-hydroxypentyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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|
C22H34N2O2
|
4
|
| 1 |
EC50 = 1995.26 nM
|
|
|
| 2 |
IC50 = 1621.81 nM
|
|
|
| 3 |
IC50 = 3311.31 nM
|
|
|
| 4 |
IC50 = 12302.69 nM
|
|
|
|
CP0378646
|
1-[3-[4-[9-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]nonyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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|
C34H51N5O2S
|
3
|
| 1 |
EC50 = 66069.34 nM
|
|
|
| 2 |
IC50 = 2454.71 nM
|
|
|
| 3 |
IC50 = 95499.26 nM
|
|
|
|
CP0175835
|
Isoptpo Hyoscine
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|
C17H21NO4
|
4
|
| 1 |
IC50 = 0.5754 nM
|
|
|
| 2 |
IC50 = 1.288 nM
|
|
|
| 3 |
IC50 = 3.802 nM
|
|
|
| 4 |
IC50 = 5.37 nM
|
|
|
|
CP0056034
|
11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
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|
C19H21N5O2
|
2
|
| 1 |
IC50 = 1.148 nM
|
|
|
| 2 |
IC50 = 1047.13 nM
|
|
|
|
CP0393625
|
1-[3-[4-(7-hydroxyheptyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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|
C24H38N2O2
|
3
|
| 1 |
IC50 = 588.84 nM
|
|
|
| 2 |
IC50 = 794.33 nM
|
|
|
| 3 |
IC50 = 1479.11 nM
|
|
|
|
CP0378645
|
1-[3-[4-(9-hydroxynonyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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|
C26H42N2O2
|
3
|
| 1 |
IC50 = 588.84 nM
|
|
|
| 2 |
IC50 = 812.83 nM
|
|
|
| 3 |
IC50 = 3630.78 nM
|
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|
