Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine; oxalic acid
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 PubChem ID
CID: 60809
SID: 15222271
Canonical SMILES
CCCCCCOc1nsnc1C1=CCCN(C)C1
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Compound Formula C14H23N3OS
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08173
Gene Name
CHRM4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 25.12 nM
   TI
   LI
   LO
   TS
2
Ki = 39.81 nM
   TI
   LI
   LO
   TS
CL000051 BHK-21
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  2
1
EC50 = 6.2 nM
   TI
   LI
   LO
   TS
2
Ki = 72 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 229 nM
   TI
   LI
   LO
   TS
2
Ki = 11.22 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 16.22 nM
   TI
   LI
   LO
   TS
2
EC50 = 186.21 nM
   TI
   LI
   LO
   TS
3
EC50 = 6309.57 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 6 nM
   TI
   LI
   LO
   TS
2
EC50 = 18 nM
   TI
   LI
   LO
   TS