Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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 PubChem ID
CID: 10236758
SID: 15238656
Canonical SMILES
CCCCC1CCN(CCCN2C(=O)CCc3ccccc23)CC1
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Compound Formula C21H32N2O
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08173
Gene Name
CHRM4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 208.93 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 275.42 nM
   TI
   LI
   LO
   TS
2
IC50 = 177.83 nM
   TI
   LI
   LO
   TS
3
IC50 = 2238.72 nM
   TI
   LI
   LO
   TS
4
IC50 = 7585.78 nM
   TI
   LI
   LO
   TS
5
IC50 = 47863.01 nM
   TI
   LI
   LO
   TS