Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
    Show/Hide
 PubChem ID
CID: 137640201
Canonical SMILES
O=C1CCc2ccccc2N1CCCN1CCC(Cc2ccccc2)CC1
    Show/Hide
Compound Formula C24H30N2O
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08173
Gene Name
CHRM4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 724.44 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 147.91 nM
   TI
   LI
   LO
   TS
2
IC50 = 1230.27 nM
   TI
   LI
   LO
   TS
3
IC50 = 8511.38 nM
   TI
   LI
   LO
   TS