Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride
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 PubChem ID
CID: 53627818
SID: 15120660
Canonical SMILES
C[N+](C)(C)CCOC(N)=O.[Cl-]
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Compound Formula C6H15ClN2O2
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08173
Gene Name
CHRM4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
2
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  5
1
EC50 = 60000 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
3
Ki = 24 nM
   TI
   LI
   LO
   TS
4
Ki = 2600 nM
   TI
   LI
   LO
   TS
5
Ki = 6309.57 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 44.67 nM
   TI
   LI
   LO
   TS
2
EC50 = 2238.72 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
ED50 = 100 nM
   TI
   LI
   LO
   TS
CL000278 RBL-2H3
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
EC50 = 290 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 75 nM
2 IC50 = 7200 nM
3 Ki = 7600 nM